成果/Result
- Ultrasensitive sensors reveal the spatiotemporal landscape of lactate metabolism in physiology and disease被引量：106收藏
- 作者：Li, Xi Zhang, Yinan Xu, Lingya Wang, Aoxue Zou, Yejun Li, Ting Huang, Li Chen, Weicai Liu, Shuning Jiang, Kun Zhang, Xiuze Wang, Dongmei Zhang, Lijuan Zhang, Zhuo Zhang, Zeyi Chen, Xianjun Jia, Wei Zhao, Aihua Yan, Xinfeng Zhou, Haimeng Zhu, Linyong Ma, Xinran Ju, Zhenyu Jia, Weiping Wang, Congrong Loscalzo, Joseph Yang, Yi Zhao, Yuzheng
- 机构：East China Univ Sci & Technol;Chinese Acad Med Sci;Chinese Acad Sci;Shanghai Jiao Tong Univ Affiliated Peoples Hosp 6;East China Normal Univ
- 来源：CELL METABOLISM 2023
- Illuminating NAD+ Metabolism in Live Cells and In Vivo Using a Genetically Encoded Fluorescent Sensor被引量：95收藏
- 作者：Zou, Yejun Wang, Aoxue Huang, Li Zhu, Xudong Hu, Qingxun Zhang, Yinan Chen, Xianjun Li, Fengwen Wang, Qiaohui Wang, Hu Liu, Renmei Zuo, Fangting Li, Ting Yao, Jing Qian, Yajin Shi, Mei Yue, Xiao Chen, Weicai Zhang, Zhuo Wang, Congrong Zhou, Yong Zhu, Linyong Ju, Zhenyu Loscalzo, Joseph Yang, Yi Zhao, Yuzheng
- 机构：East China Univ Sci & Technol;Chinese Acad Sci;East China Univ Sci & Technol;Hangzhou Normal Univ;Shanghai Jiao Tong Univ
- 来源：DEVELOPMENTAL CELL 2020
- Analysis of redox landscapes and dynamics in living cells and in vivo using genetically encoded fluorescent sensors被引量：83收藏
- 作者：Zou, Yejun Wang, Aoxue Shi, Mei Chen, Xianjun Liu, Renmei Li, Ting Zhang, Chenxia Zhang, Zhuo Zhu, Linyong Ju, Zhenyu Loscalzo, Joseph Yang, Yi Zhao, Yuzheng
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;Jinan Univ;Harvard Med Sch
- 来源：NATURE PROTOCOLS 2018
- Synergistic protective effect of picroside II and NGF on PC12 cells against oxidative stress induced by H2O2被引量：42收藏
- 作者：Liu, Jian-Wen Yu, You-Jun Zheng, Pei-yong Zhang, Xiao-dong Li, Ting Cao, Yan Guo, Ming-chuan
- 机构：E China Univ Sci & Technol;Shanghai Tradit Chinese Med Univ
- 来源：PHARMACOLOGICAL REPORTS 2007
- 关键词：hydrogen peroxide nerve growth factor PC12 cells picroside II reactive oxygen species
- Synthetic dual-input mammalian genetic circuits enable tunable and stringent transcription control by chemical and light被引量：36收藏
- 作者：Chen, Xianjun Li, Ting Wang, Xue Du, Zengmin Liu, Renmei Yang, Yi
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol;E China Univ Sci & Technol;E China Univ Sci & Technol
- 来源：NUCLEIC ACIDS RESEARCH 2016
- A synthetic BRET-based optogenetic device for pulsatile transgene expression enabling glucose homeostasis in mice被引量：34收藏
- 作者：Li, Ting Chen, Xianjun Qian, Yajie Shao, Jiawei Li, Xie Liu, Shuning Zhu, Linyong Zhao, Yuzheng Ye, Haifeng Yang, Yi
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Chinese Acad Sci;East China Normal Univ;East China Normal Univ
- 来源：NATURE COMMUNICATIONS 2021
- The neuroprotective effect of picroside II from Hu-Huang-Lian against oxidative stress被引量：33收藏
- 作者：Li, Ting Liu, Jian-Wen Zhang, Xiao-Dong Guo, Ming-Chuan Ji, Guang
- 机构：E China Univ Sci & Technol;Shanghai Univ TCM
- 来源：AMERICAN JOURNAL OF CHINESE MEDICINE 2007
- 关键词：neuroprotection oxidative stress pricroside II Hu-Huang-Lian aluminium glutamate
- Antidiabetic activity of lipophilic (-)-epigallocatechin-3-gallate derivative under its role of α-glucosidase inhibition被引量：33收藏
- 作者：Li, Ting Liu, Jianwen Zhang, Xiaodong Ji, Guang
- 机构：E China Univ Sci & Technol;Shanghai Univ Tradit Chinese Med
- 来源：BIOMEDICINE & PHARMACOTHERAPY 2007
- 关键词：alpha-glucosidase inhibitor blood glucose postprandial hyperglycemia
- Comprehensive multiscale analysis of lactate metabolic dynamics in vitro and in vivo using highly responsive biosensors被引量：27收藏
- 作者：Wang, Aoxue Zou, Yejun Liu, Shuning Zhang, Xiuze Li, Ting Zhang, Lijuan Wang, Ruwen Xia, Yale Li, Xie Zhang, Zhuo Liu, Tiemin Ju, Zhenyu Wang, Ru Loscalzo, Joseph Yang, Yi Zhao, Yuzheng
- 机构：East China Univ Sci & Technol;Chinese Acad Med Sci;Shanghai Univ Sport;Fudan Univ;Jinan Univ
- 来源：NATURE PROTOCOLS 2024
- Lighting up arginine metabolism reveals itsfunctional diversity in physiology and pathology被引量：21收藏
- 作者：Li, Rui Li, Yan Jiang, Kun Zhang, Lijuan Li, Ting Zhao, Aihua Zhang, Zhuo Xia, Yale Ge, Kun Chen, Yaqiong Wang, Chengnuo Tang, Weitao Liu, Shuning Lin, Xiaoxi Song, Yuqin Mei, Jie Xiao, Chun Wang, Aoxue Zou, Yejun Li, Xie Chen, Xianjun Ju, Zhenyu Jia, Wei Loscalzo, Joseph Sun, Yu Fang, Wei Yang, Yi Zhao, Yuzheng
- 机构：East China Univ Sci & Technol;Chinese Acad Med Sci;Univ Chinese Acad Sci;Shanghai Jiao Tong Univ;Shanghai Jiao Tong Univ
- 来源：CELL METABOLISM 2025
- Thermo-responsive gold nanorod vesicles for combined NIR-II photothermal therapy and chemotherapy of solid tumors被引量：19收藏
- 作者：Xing, Wenqian Li, Ting Yang, Guangze Wu, Shuqin Pang, Bailu Xu, Yufang Qian, Xuhong Zhu, Weiping
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：ACTA BIOMATERIALIA 2025
- 关键词：Gold nanorod vesicle Upper critical solution temperature Near-infrared-II Photothermal therapy Controlled-release
- A Single-Component Optogenetic Gal4-UAS System Allows Stringent Control of Gene Expression in Zebrafish and Drosophila被引量：15收藏
- 作者：Qian, Yajie Li, Ting Zhou, Siyu Chen, Xianjun Yang, Yi
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：ACS SYNTHETIC BIOLOGY 2023
- 关键词：optogenetics single-component gene expression Gal4-UAS
- A light-switchable bidirectional expression module allowing simultaneous regulation of multiple genes被引量：10收藏
- 作者：Chen, Xianjun Li, Ting Wang, Xue Yang, Yi
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol;E China Univ Sci & Technol
- 来源：BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 2015
- 关键词：Bidirectional Gene expression Light Simultaneous regulation
- Insights into the synergistic mechanism of target resistance: A case study of N. lugens RDL-GABA receptors and fipronil被引量：7收藏
- 作者：Li, Ting Zhou, Cong Zheng, Nan Yang, Hongbin Kuang, Guanglin Shao, Xusheng Li, Zhong Cheng, Jiagao
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：BIOPHYSICAL CHEMISTRY 2020
- 关键词：Resistance RDL-GABA receptor Fipronil Molecular dynamics simulation Homology modelling
- Live-cell imaging reveals redox metabolic reprogramming during zygotic genome activation被引量：6收藏
- 作者：Sun, Hao Zhang, Zhuo Li, Tianda Li, Ting Chen, Weicai Pan, Tianshi Fang, Sen Liu, Chao Zhang, Ying Wang, Leyun Feng, Guihai Li, Wei Zhou, Qi Zhao, Yuzheng
- 机构：Chinese Acad Sci;Chinese Acad Sci;Beijing Inst Stem Cell & Regenerat Med;Univ Chinese Acad Sci;East China Univ Sci & Technol
- 来源：JOURNAL OF CELLULAR PHYSIOLOGY 2023
- 关键词：biosensor dynamic imaging embryo development metabolite detection single cell
- Transferrin-targeting pH-responsive and biodegradable mesoporous silica nanohybrid for nitric oxide-sensitized chemotherapy of cancer被引量：6收藏
- 作者：Li, Ting Cheng, Di Xu, Xiu Wang, Bin Xing, Wenqian Xu, Yufang Qian, Xuhong Yang, Youjun Zhu, Weiping
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：COLLOIDS AND SURFACES B-BIOINTERFACES 2025
- 关键词：PH-responsive Biodegradable mesoporous organosilica Nitric oxide sensitization Drug-resistant inhibition
- A Catalyst and Base Free Approach to Polycyclic Aromatic Compounds via Intramolecular [2+2] and retro-[2+2] Cycloadditions被引量：5收藏
- 作者：Lu, Aoyun Li, Tao Wang, Jiayi Song, Gonghua
- 机构：East China Univ Sci & Technol
- 来源：ASIAN JOURNAL OF ORGANIC CHEMISTRY 2021
- 关键词：polycyclic aromatic compounds catalyst-free microwave [2+2] cycloaddition retro-[2+2] cycloaddition
- NADPHnet: a novel strategy to predict compounds for regulation of NADPH metabolism via network-based methods被引量：4收藏
- 作者：Pan, Fei Wang, Cheng-nuo Yu, Zhuo-hang Wu, Zeng-rui Wang, Ze Lou, Shang Li, Wei-hua Liu, Gui-xia Li, Ting Zhao, Yu-zheng Tang, Yun
- 机构：East China Univ Sci & Technol
- 来源：ACTA PHARMACOLOGICA SINICA 2024
- 关键词：NADPH metabolism network-based inference natural product computational prediction
- Structural diversity derivatization and studies on the nematicidal activity of tropane derivatives被引量：1收藏
- 作者：Lu, Aoyun Zheng, Yiting Li, Tao Wang, Jiayi Song, Gonghua
- 机构：East China Univ Sci & Technol
- 来源：PHYTOCHEMISTRY LETTERS 2024
- 关键词：Nematicidal activity Tropane Lead optimization Bioisosteric replacement
- Combined heat and exercise stress disrupt gut microbiota and promote microbial translocation被引量：0收藏
- 作者：Min, Leizi Ablitip, Alimjan Wang, Qingyuan Li, Ting Di, Qian Ma, Xindong Fang, Wen
- 机构：East China Univ Sci & Technol;Tsinghua Univ;East China Univ Sci & Technol;Tsinghua Univ;Tsinghua Univ
- 来源：FRONTIERS IN MICROBIOLOGY 2026
- 关键词：bacterial translocation exertional heat stroke gut microbiota heat stress intestinal barrier
