成果/Result
- Palladium nanoparticles supported on functional ionic liquid modified magnetic nanoparticles as recyclable catalyst for room temperature Suzuki reaction被引量：93收藏
- 作者：Wang, Jiayi Xu, Beiling Sun, Haiyang Song, Gonghua
- 机构：E China Univ Sci & Technol
- 来源：TETRAHEDRON LETTERS 2013
- 关键词：Magnetic nanoparticles Suzuki reaction Ionic liquid Palladium
- New tricks for human farnesyltransferase inhibitor: cancer and beyond被引量：59收藏
- 作者：Wang, Jingyuan Yao, Xue Huang, Jin
- 机构：East China Univ Sci & Technol
- 来源：MEDCHEMCOMM 2017
- A copper-catalyzed cascade borylation/Petasis reaction for synthesis of regioselective 2H-chromenes under catalytic amine conditions被引量：39收藏
- 作者：Yang, Xiaoning Wu, Shuyan Wang, Jiayi Peng, Yanqing Song, Gonghua
- 机构： Shanghai Key Laboratory of Chemical Biology
- 来源：Organic Chemistry Frontiers 2025
- 关键词：Amines - Catalysis - Copper - Methyl ester - Regioselectivity - Scaffolds - Sustainable chemistry - Synthesis (chemical)
- Reusable Pd nanoparticles immobilized on functional ionic liquid co-polymerized with styrene for Suzuki reactions in water-ethanol solution被引量：37收藏
- 作者：Wang, Jiayi Song, Gonghua Peng, Yanqing
- 机构：E China Univ Sci & Technol
- 来源：TETRAHEDRON LETTERS 2011
- 关键词：Suzuki reaction Ionic liquid Co-polymer Palladium
- Moracin C, A Phenolic Compound Isolated from Artocarpus heterophyllus, Suppresses Lipopolysaccharide-Activated Inflammatory Responses in Murine Raw264.7 Macrophages被引量：34收藏
- 作者：Yao, Xue Wu, Dang Dong, Ningning Ouyang, Ping Pu, Jiaqian Hu, Qian Wang, Jingyuan Lu, Weiqiang Huang, Jin
- 机构：East China Univ Sci & Technol;East China Normal Univ;East China Normal Univ
- 来源：INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2016
- 关键词：inflammation MAPKs Moracin C NF-kappa B phenols
- Room temperature multicomponent synthesis of diverse propargylamines using magnetic CuFe2O4 nanoparticle as an efficient and reusable catalyst被引量：34收藏
- 作者：Zhang, Jia-Yu Huang, Xi Shen, Qiao-Ying Wang, Jia-Yi Song, Gong-Hua
- 机构：East China Univ Sci Technol
- 来源：CHINESE CHEMICAL LETTERS 2018
- 关键词：Multicomponent reaction Magnetic catalyst Recycle Copper ferrite Propargylamine
- Catalyst-free chemoselective conjugate addition and reduction of α,β-unsaturated carbonyl compounds via a controllable boration/protodeboronation cascade pathway被引量：32收藏
- 作者：Huang, Xi Hu, Junjie Wu, Mengying Wang, Jiayi Peng, Yanqing Song, Gonghua
- 机构：East China Univ Sci & Technol
- 来源：GREEN CHEMISTRY 2018
- Amino Acid-derived Protic Ionic Liquids: Physicochemical Properties and Behaviour as Amphiphile Self-assembly Media被引量：31收藏
- 作者：Wang, Jiayi Greaves, Tamar L. Kennedy, Danielle F. Weerawardena, Asoka Song, Gonghua Drummond, Calum J.
- 机构：CMSE;E China Univ Sci & Technol
- 来源：AUSTRALIAN JOURNAL OF CHEMISTRY 2011
- 关键词：Amino acids - Dyes - Ionic liquids - Nitrates - Self assembly - Cationic surfactants - Esters - Carboxylation - Glass transition - Positive ions
- Myricetin is a novel inhibitor of human inosine 5′-monophosphate dehydrogenase with anti-leukemia activity被引量：27收藏
- 作者：Pan, Huiling Hu, Qian Wang, Jingyuan Liu, Zehui Wu, Dang Lu, Weiqiang Huang, Jin
- 机构：East China Univ Sci & Technol;East China Normal Univ;East China Normal Univ
- 来源：BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 2016
- 关键词：Inosine 5 '-monophosphate dehydrogenase Myricetin Leukemia Guanine nucleotide Anti-cancer
- Drug Repurposing for Newly Emerged Diseases via Network-based Inference on a Gene-disease-drug Network被引量：27收藏
- 作者：Qin, Li Wang, Jiye Wu, Zengrui Li, Weihua Liu, Guixia Tang, Yun
- 机构：East China Univ Sci & Technol
- 来源：MOLECULAR INFORMATICS 2022
- 关键词：Drug repurposing Disease-drug associations Network-based inference
- 3-Butyl-1-methylimidazolinium borohydride ([bmim][BH4])-a novel reducing agent for the selective reduction of carbon-carbon double bonds in activated conjugated alkenes被引量：26收藏
- 作者：Wang, Jiayi Song, Gonghua Peng, Yanqing Zhu, Yidong
- 机构：E China Univ Sci & Technol
- 来源：TETRAHEDRON LETTERS 2008
- 关键词：Reduction Double bond Ionic reducing reagent Selective
- Metal-free multicomponent coupling reaction of aliphatic amines, formaldehyde, organoboronic acids, and propiolic acids for the synthesis of diverse propargylamines被引量：22收藏
- 作者：Wang, Jiayi Shen, Qiaoying Zhang, Jiayu Song, Gonghua
- 机构：E China Univ Sci & Technol
- 来源：TETRAHEDRON LETTERS 2015
- 关键词：Multicomponent reaction Metal-free Propargylamines Petasis-borono Mannich reaction Decarboxylative coupling
- Synthesis of tertiary propargylamines via a rationally designed multicomponent reaction of primary amines, formaldehyde, arylboronic acids and alkynes被引量：20收藏
- 作者：Wang, Jiayi Shen, Qiaoying Li, Pinzhen Peng, Yanqing Song, Gonghua
- 机构：E China Univ Sci & Technol;Shanghai Res Inst Chem Ind
- 来源：ORGANIC & BIOMOLECULAR CHEMISTRY 2014
- 关键词：Amines - Hydrocarbons
- Coptisine, a natural alkaloid from Coptidis Rhizoma, inhibits plasmodium falciparum dihydroorotate dehydrogenase被引量：20收藏
- 作者：Lang, Li Hu, Qian Wang, Jingyuan Liu, Zehui Huang, Jin Lu, Weiqiang Huang, Ying
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;Guangdong Inst Drug Control
- 来源：CHEMICAL BIOLOGY & DRUG DESIGN 2018
- 关键词：coptisine dihydroorotate dehydrogenase plasmodium falciparum pyrimidine biosynthesis traditional Chinese medicine
- Microwave-Assisted Ligand-Free Nickel-Catalyzed β-Boration of α,β-Unsaturated Carbonyl Compounds with Bis(pinacolato)diboron被引量：19收藏
- 作者：Huang, Xi Wang, Mingming Wu, Mengying Wang, Jiayi Peng, Yanqing Song, Gonghua
- 机构：East China Univ Sci & Technol
- 来源：CHEMISTRYSELECT 2017
- 关键词：bis(pinacolato)diboron ligand-free nickel catalyst alpha,beta-unsaturated carbonyl compounds beta-boration
- Ligand-Free Nickel-Catalysed 1,4-Addition of Arylboronic Acids to α,β-Unsaturated Carbonyl Compounds被引量：18收藏
- 作者：Chen, Wen Sun, Lu Huang, Xi Wang, Jiayi Peng, Yanqing Song, Gonghua
- 机构：E China Univ Sci & Technol
- 来源：ADVANCED SYNTHESIS & CATALYSIS 2015
- 关键词：1,4-addition arylboronic acids ligand-free conditions nickel alpha,beta-unsaturated carbonyl compounds
- Concise synthesis of aromatic tertiary amines via a double Petasis-borono Mannich reaction of aromatic amines, formaldehyde, and organoboronic acids被引量：18收藏
- 作者：Wang, Jiayi Li, Pinzhen Shen, Qiaoying Song, Gonghua
- 机构：E China Univ Sci & Technol
- 来源：TETRAHEDRON LETTERS 2014
- 关键词：Petasis-borono Mannich reaction Organoboronic acids Aromatic amines Formaldehyde Multi-component reaction
- IDL-PPBopt: A Strategy for Prediction and Optimization of Human Plasma Protein Binding of Compounds via an Interpretable Deep Learning Method被引量：16收藏
- 作者：Lou, Chaofeng Yang, Hongbin Wang, Jiye Huang, Mengting Li, Weihua Liu, Guixia Lee, Philip W. Tang, Yun
- 机构：East China Univ Sci & Technol
- 来源：JOURNAL OF CHEMICAL INFORMATION AND MODELING 2022
- 关键词：Biochemistry - Deep learning - Learning algorithms - Learning systems - Mean square error - Pharmacokinetics - Proteins - Statistical tests
- Synthesis and nematicidal activity of piperazinedione derivatives based on the natural product Barettin被引量：15收藏
- 作者：Sun, Haiyang Li, Hui Wang, Jiayi Song, Gonghua
- 机构：East China Univ Sci & Technol
- 来源：CHINESE CHEMICAL LETTERS 2018
- 关键词：5-HT Barettin Nature product Nematicidal activity Piperazinedione derivatives
- A simple and efficient synthesis of fused morpholine pyrrolidines/piperdines with potential insecticidal activities被引量：15收藏
- 作者：Wang, Jiayi Xu, Beiling Si, Shanyu Li, Hui Song, Gonghua
- 机构：E China Univ Sci & Technol
- 来源：MOLECULAR DIVERSITY 2014
- 关键词：Multicomponent Petasis-borono Mannich reaction Fused morpholines Insecticidal activity MCR
- Direct olefination of benzaldehydes into 1,3-diarylpropenes via a copper-catalyzed heterodomino Knoevenagel- decarboxylation-Csp3-H activation sequence被引量：14收藏
- 作者：Zhao, Yaping Sun, Lu Zeng, Tieqiang Wang, Jiayi Peng, Yanqing Song, Gonghua
- 机构：E China Univ Sci & Technol
- 来源：ORGANIC & BIOMOLECULAR CHEMISTRY 2014
- 关键词：Copper - Carboxylation - Catalysis
- Development of a Multi-Target Strategy for the Treatment of Vitiligo via Machine Learning and Network Analysis Methods被引量：14收藏
- 作者：Wang, Jiye Luo, Lin Ding, Qiong Wu, Zengrui Peng, Yayuan Li, Jie Wang, Xiaoqin Li, Weihua Liu, Guixia Zhang, Bo Tang, Yun
- 机构：East China Univ Sci & Technol;Shihezi Univ;Chengdu Univ
- 来源：FRONTIERS IN PHARMACOLOGY 2021
- 关键词：kaempferide machine learning melanogenesis multi-target strategy network analysis vitiligo
- Polymerized functional ionic liquid supported Pd nanoparticle catalyst for reductive homocoupling of aryl halides被引量：13收藏
- 作者：Wang, Jiayi Li, Yuan Li, Pinzhen Song, Gonghua
- 机构：E China Univ Sci & Technol
- 来源：MONATSHEFTE FUR CHEMIE 2013
- 关键词：Heterogeneous catalysis Polymerization Reductive homocoupling Aryl halides Palladium
- Catalyst-free chemoselective α-sulfenylation/β-thiolation for α,β-unsaturated carbonyl compounds被引量：13收藏
- 作者：Huang, Xi Li, Juan Li, Xiang Wang, Jiayi Peng, Yanqing Song, Gonghua
- 机构：East China Univ Sci & Technol
- 来源：RSC ADVANCES 2019
- 关键词：Transition metals - Carbonyl compounds - Chemical reactions - Unsaturated compounds - Catalysts
- MPSM-DTI: prediction of drug-target interaction via machine learning based on the chemical structure and protein sequence被引量：13收藏
- 作者：Peng, Yayuan Wang, Jiye Wu, Zengrui Zheng, Lulu Wang, Biting Liu, Guixia Li, Weihua Tang, Yun
- 机构：East China Univ Sci & Technol
- 来源：DIGITAL DISCOVERY 2022
- Pathway-Based Drug Repurposing with DPNetinfer: A Method to Predict Drug-Pathway Associations via Network-Based Approaches被引量：12收藏
- 作者：Wang, Jiye Wu, Zengrui Peng, Yayuan Li, Weihua Liu, Guixia Tang, Yun
- 机构：East China Univ Sci & Technol
- 来源：JOURNAL OF CHEMICAL INFORMATION AND MODELING 2021
- 关键词：Computational methods - Diseases
- Ground cover vegetation promotes biological control and yield in pear orchards被引量：11收藏
- 作者：Ji, Xiang-Yun Wang, Jin-Yan Dainese, Matteo Zhang, Hao Chen, Yi-Juan Cavalieri, Andrea Jiang, Jie-Xian Wan, Nian-Feng
- 机构：East China Univ Sci & Technol;EURAC Res;Univ Copenhagen;East China Univ Sci & Technol
- 来源：JOURNAL OF APPLIED ENTOMOLOGY 2022
- 关键词：agricultural biodiversity biological control ecological intensification ecosystem services invertebrate herbivore natural enemy pesticide reduction
- Plant defense metabolites influence the interaction between an insect herbivore and an entomovirus被引量：11收藏
- 作者：Wang, Jin-Yan Fan, Neng-Neng Yuan, Yuan Bass, Chris Siemann, Evan Ji, Xiang-Yun Jiang, Jie-Xian Wan, Nian-Feng
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Univ Exeter;Rice Univ
- 来源：CURRENT BIOLOGY 2024
- 关键词：Highlights Plant secondary metabolites (PSMs) affect caterpillars' plant phenolics
- Discovery of Natural Products Targeting NQO1 via an Approach Combining Network-Based Inference and Identification of Privileged Substructures被引量：10收藏
- 作者：Wu, Zengrui Wang, Qiaohui Yang, Hongbin Wang, Jiye Li, Weihua Liu, Guixia Yang, Yi Zhao, Yuzheng Tang, Yun
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Chinese Acad Sci
- 来源：JOURNAL OF CHEMICAL INFORMATION AND MODELING 2021
- 关键词：Neurodegenerative diseases - Quinone
- Copper-Catalyzed Three-Component Reactions of α-Ketoaldehyde, 1,3-Dicarbonyl Compound, and Organic Boronic Acid in Water: A Route to 1,4-Diketones被引量：10收藏
- 作者：Xia, Qi Li, Xiang Fu, Xi Zhou, Yaxuan Peng, Yanqing Wang, Jiayi Song, Gonghua
- 机构：East China Univ Sci & Technol
- 来源：JOURNAL OF ORGANIC CHEMISTRY 2021
- 关键词：Catalysis - Copper
