成果/Result
- The potential and challenge of microalgae as promising future food sources被引量：139收藏
- 作者：Chen, Cheng Tang, Tao Shi, Qianwen Zhou, Zuodong Fan, Jianhua
- 机构：East China Univ Sci & Technol;Chinese Acad Sci;East China Univ Sci & Technol;East China Univ Sci & Technol;Shihezi Univ
- 来源：TRENDS IN FOOD SCIENCE & TECHNOLOGY 2022
- 关键词：Microalgae Biomass Food Safety Production
- Efficient accumulation of high-value bioactive substances by carbon to nitrogen ratio regulation in marine microalgae Porphyridium purpureum被引量：89收藏
- 作者：Li, Shaohua Ji, Liang Chen, Cheng Zhao, Shuxin Sun, Meng Gao, Zhengquan Wu, Haizhen Fan, Jianhua
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Shandong Univ Technol
- 来源：BIORESOURCE TECHNOLOGY 2020
- 关键词：Porphyridium purpureum C/N ratio Phycoerythrin Exopolysaccharides Fatty acids
- Advances in the production of bioactive substances from marine unicellular microalgae Porphyridium spp.被引量：78收藏
- 作者：Li, Shaohua Ji, Liang Shi, Qianwen Wu, Haizhen Fan, Jianhua
- 机构：East China Univ Sci & Technol;Hainan Univ;East China Univ Sci & Technol
- 来源：BIORESOURCE TECHNOLOGY 2019
- 关键词：Red algae Cultivation Metabolic regulation Application Bioactive compounds
- Bioremediation of phenolic pollutants by algae-current status and challenges被引量：60收藏
- 作者：Wu, Ping Zhang, Zhaofei Luo, Yeling Bai, Yunpeng Fan, Jianhua
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：BIORESOURCE TECHNOLOGY 2022
- 关键词：Algae Phenolic pollutants Removal mechanisms Industrial value
- Phycobiliproteins from algae: Current updates in sustainable production and applications in food and health被引量：58收藏
- 作者：Ji, Liang Qiu, Sheng Wang, Zhiheng Zhao, Chenni Tang, Bo Gao, Zhengquan Fan, Jianhua
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Shihezi Univ;Nantong Focusee Biotechnol Co Ltd;Binzhou Med Univ
- 来源：FOOD RESEARCH INTERNATIONAL 2023
- 关键词：Phycoerythrin Phycocyanin Allophycocyanin Algae Food Biomedicine
- Evaluation of Microalgae as Immunostimulants and Recombinant Vaccines for Diseases Prevention and Control in Aquaculture被引量：58收藏
- 作者：Ma, Ke Bao, Qiuwen Wu, Yue Chen, Siwei Zhao, Shuxin Wu, Haizhen Fan, Jianhua
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY 2020
- 关键词：aquaculture industry microalgae immunostimulant oral vaccine polymicrobial infections
- Dietary supplementation with microalgae enhances the zebrafish growth performance by modulating immune status and gut microbiota被引量：50收藏
- 作者：Ma, Ke Chen, Siwei Wu, Yue Ma, Yiting Qiao, Haochen Fan, Jianhua Wu, Haizhen
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 2022
- 关键词：Microalgae Zebrafish Growth performance Immune status Gut microbiota
- Characterization of Anthocyanins in Perilla frutescens var. acuta Extract by Advanced UPLC-ESI-IT-TOF-MSn Method and Their Anticancer Bioactivity被引量：41收藏
- 作者：He, Yan-Kang Yao, You-Yuan Chang, Ya-Ning
- 机构：E China Univ Sci & Technol
- 来源：MOLECULES 2015
- 关键词：Perilla frutescens var acuta anthocyanins ESI-IT-TOF-MSn Hela cells apoptosis
- The Novel Transcriptional Regulator LmbU Promotes Lincomycin Biosynthesis through Regulating Expression of Its Target Genes in Streptomyces lincolnensis被引量：40收藏
- 作者：Hou, Bingbing Lin, Yanwei Wu, Haizhen Guo, Meijin Petkovic, Hrvoje Tao, Liyuan Zhu, Xiaoyu Ye, Jiang Zhang, Huizhan
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Univ Ljubljana
- 来源：JOURNAL OF BACTERIOLOGY 2018
- 关键词：LmbU LmbU homologues Streptomyces cluster-situated regulator lincomycin regulatory protein
- Flocculation of Chlamydomonas reinhardtii with Different Phenotypic Traits by Metal Cations and High pH被引量：31收藏
- 作者：Fan, Jianhua Zheng, Lvhong Bai, Yunpeng Saroussi, Shai Grossman, Arthur R.
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Carnegie Inst Sci
- 来源：FRONTIERS IN PLANT SCIENCE 2017
- 关键词：flocculation cell wall deficient Chlamydomonas multivalent metal ions microalgae pH algal biotechnology
- AdpAlin, a Pleiotropic Transcriptional Regulator, Is Involved in the Cascade Regulation of Lincomycin Biosynthesis in Streptomyces lincolnensis被引量：29收藏
- 作者：Kang, Yajing Wang, Yingying Hou, Bingbing Wang, Ruida Ye, Jiang Zhu, Xiaoyu Wu, Haizhen Zhang, Huizhan
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：FRONTIERS IN MICROBIOLOGY 2019
- 关键词：AdpA lincomycin Streptomyces lincolnensis transcriptional regulator cascade regulation
- MAPKpathway-related tyrosine phosphatases regulate development, secondary metabolism and pathogenicity in fungusAspergillus flavus被引量：29收藏
- 作者：Yang, Guang Cao, Xiaohong Ma, Genli Qin, Ling Wu, Yuanzhen Lin, Jian Ye, Peng Yuan, Jun Wang, Shihua
- 机构：Fujian Agr & Forestry Univ;Fujian Agr & Forestry Univ;East China Univ Sci & Technol
- 来源：ENVIRONMENTAL MICROBIOLOGY 2020
- Transgenic eukaryotic microalgae as green factories: providing new ideas for the production of biologically active substances被引量：27收藏
- 作者：Shi, Qianwen Chen, Cheng Zhang, Wei Wu, Ping Sun, Meng Wu, Hui Wu, Haizhen Fu, Pengcheng Fan, Jianhua
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Hainan Univ
- 来源：JOURNAL OF APPLIED PHYCOLOGY 2021
- 关键词：Eukaryotic microalgae Genetic engineering Metabolism Biopharmaceuticals production Therapeutic proteins
- Global regulator BldA regulates morphological differentiation and lincomycin production in Streptomyces lincolnensis被引量：26收藏
- 作者：Hou, Bingbing Tao, Liyuan Zhu, Xiaoyu Wu, Wei Guo, Meijin Ye, Jiang Wu, Haizhen Zhang, Huizhan
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 2018
- 关键词：S. lincolnensis bldA Leucine codon Morphological differentiation Lincomycin production Regulatory pathway
- Physiological and transcriptome analysis elucidates the metabolic mechanism of versatile Porphyridium purpureum under nitrogen deprivation for exopolysaccharides accumulation被引量：26收藏
- 作者：Ji, Liang Li, Shaohua Chen, Cheng Jin, Haojie Wu, Haizhen Fan, Jianhua
- 机构：East China Univ Sci & Technol;Beijing Forestry Univ;East China Univ Sci & Technol
- 来源：BIORESOURCES AND BIOPROCESSING 2021
- 关键词：Porphyridium purpureum Nitrogen deprivation Transcriptome analysis Exopolysaccharides Polyunsaturated fatty acids Phycoerythrin
- Effective Therapeutic Drug Delivery by GALA3, an Endosomal Escape Peptide with Reduced Hydrophobicity被引量：25收藏
- 作者：Li, Chen Cao, Xue-Wei Zhao, Jian Wang, Fu-Jun
- 机构：East China Univ Sci & Technol;Zhejiang Fonow Med Co Ltd;Shanghai R&D Ctr Standardizat Chinese Med;Shanghai Univ Tradit Chinese Med;East China Univ Sci & Technol
- 来源：JOURNAL OF MEMBRANE BIOLOGY 2020
- 关键词：Endosomal escape HBP GALA3 BLF1
- Efficient degradation of sulfadiazine by photosynthetic cyanobacteria Synechocystis sp. PCC 6803 coupling with recombinant laccase strategy被引量：23收藏
- 作者：Wu, Ping Hu, Tianyouzi Sun, Liyun Fan, Jianhua
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;Shihezi Univ;130 Meilong Rd
- 来源：CHEMICAL ENGINEERING JOURNAL 2023
- 关键词：Synechocystis Sulfadiazine Bioremediation Laccase Microalgae
- Recombinant expression and purification of a MAP30-cell penetrating peptide fusion protein with higher anti-tumor bioactivity被引量：23收藏
- 作者：Lv, Qiang Yang, Xu-Zhong Fu, Long-Yun Lu, Yv-Ting Lu, Yan-Hua Zhao, Jian Wang, Fu-Jun
- 机构：E China Univ Sci & Technol;Zhejiang Reachall Pharmaceut Co Ltd;Shanghai Univ Chinese Tradit Med
- 来源：PROTEIN EXPRESSION AND PURIFICATION 2015
- 关键词：Recombinant Momordica Antiviral Protein 30 Kd (rMAP30) Ribosome inactivating protein Cell Penetrating Peptide Ni-NTA purification Anti-tumor activity
- Circadian rhythm promotes the biomass and amylose hyperaccumulation by mixotrophic cultivation of marine microalga Platymonas helgolandica被引量：21收藏
- 作者：Shi, Qianwen Chen, Cheng He, Tingwei Fan, Jianhua
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;Shihezi Univ
- 来源：BIOTECHNOLOGY FOR BIOFUELS AND BIOPRODUCTS 2022
- 关键词：Microalgae Starch Circadian rhythm Mixotrophy Amylose
- Towards green biomanufacturing of high-value recombinant proteins using promising cell factory: Chlamydomonas reinhardtii chloroplast被引量：21收藏
- 作者：Ma, Ke Deng, Lei Wu, Haizhen Fan, Jianhua
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Shihezi Univ
- 来源：BIORESOURCES AND BIOPROCESSING 2022
- 关键词：Chlamydomonas reinhardtii Chloroplast Synthetic biology Green factory Selectable marker Protein expression
- Complete genome sequence of high-yield strain S. lincolnensis B48 and identification of crucial mutations contributing to lincomycin overproduction被引量：19收藏
- 作者：Wang, Ruida Kong, Fanjing Wu, Haizhen Hou, Bingbing Kang, Yajing Cao, Yuan Duan, Shiwei Ye, Jiang Zhang, Huizhan
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Ningbo Univ
- 来源：SYNTHETIC AND SYSTEMS BIOTECHNOLOGY 2020
- 关键词：Lincomycin Comparative genomics Regulation Overproduction
- Discovery of 16-Demethylrifamycins by Removing the Predominant Polyketide Biosynthesis Pathway in Micromonospora sp. Strain TP-A0468被引量：17收藏
- 作者：Zhou, Qiang Luo, Guang-Cai Zhang, Huizhan Tang, Gang-Li
- 机构：East China Univ Sci & Technol;Chinese Acad Sci
- 来源：APPLIED AND ENVIRONMENTAL MICROBIOLOGY 2019
- 关键词：ansamycins cross talk genome mining metabolic flux redirection rifamycin
- Assessment of light distribution model for marine red microalga Porphyridium purpureum for sustainable production in photobioreactor被引量：17收藏
- 作者：Li, Shaohua Huang, Jianke Ji, Liang Chen, Cheng Wu, Ping Zhang, Wei Tan, Gaoyi Wu, Haizhen Fan, Jianhua
- 机构：East China Univ Sci & Technol;Hohai Univ;Hunan Inst Engn;East China Univ Sci & Technol
- 来源：ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS 2021
- 关键词：Red algae Biomass productivity Sustainability production Light distribution model Volume-averaged light intensity
- Freeze-thaw-assisted aqueous two-phase system as a green and low-cost option for analytical grade B-phycoerythrin production from unicellular microalgae Porphyridium purpureum被引量：17收藏
- 作者：Ji, Liang Liu, Yueling Luo, Jianquan Fan, Jianhua
- 机构：East China Univ Sci & Technol;Chinese Acad Sci;East China Univ Sci & Technol;Shihezi Univ;130 Meilong Rd
- 来源：ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS 2022
- 关键词：Microalgae Porphyridium purpureum Phycoerythrin Freeze-thaw Aqueous two-phase system
- Developmental regulator RamRsl controls both morphological development and lincomycin biosynthesis in Streptomyces lincolnensis被引量：16收藏
- 作者：Wang, Ruida Cao, Yuan Kong, Fanjing Hou, Bingbing Zhao, Jiaqi Kang, Yajing Ye, Jiang Wu, Haizhen Zhang, Huizhan
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：JOURNAL OF APPLIED MICROBIOLOGY 2022
- 关键词：lincomycin biosynthesis morphology RamR Streptomyces lincolnensis transcriptional regulation
- Comparative transcriptome analyses of oleaginous Botryococcus braunii race A reveal significant differences in gene expression upon cobalt enrichment被引量：16收藏
- 作者：Cheng, Pengfei Zhou, Chengxu Wang, Yan Xu, Zhihui Xu, Jilin Zhou, Dongqing Zhang, Yinghui Wu, Haizhen Zhang, Xuezhi Liu, Tianzhong Tang, Ming Yang, Qiyong Yan, Xiaojun Fan, Jianhua
- 机构：Ningbo Univ;East China Univ Sci & Technol;East China Univ Sci & Technol;Chinese Acad Sci;Chinese Acad Sci
- 来源：BIOTECHNOLOGY FOR BIOFUELS 2018
- 关键词：Botryococcus braunii Cobalt treatment Physiological response Transcriptome Regulation mechanism
- Improved breast cancer cell-specific intracellular drug delivery and therapeutic efficacy by coupling decoration with cell penetrating peptide and SP90 peptide被引量：15收藏
- 作者：Fan, Li-Qiang Du, Guo-Xiu Li, Peng-Fei Li, Ming-Wei Sun, Yao Zhao, Li-Ming
- 机构：East China Univ Sci & Technol
- 来源：BIOMEDICINE & PHARMACOTHERAPY 2016
- 关键词：Cell-penetrating peptide Homing peptide Targeted drug delivery Breast cancer therapy VPR
- AflQ1-Q2 represses lincomycin biosynthesis via multiple cascades in Streptomyces lincolnensis被引量：15收藏
- 作者：Wang, Ruida Zhou, Tianyu Kong, Fanjing Hou, Bingbing Ye, Jiang Wu, Haizhen Zhang, Huizhan
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 2023
- 关键词：AflQ1-Q2 Streptomyces lincolnensis Two-component system Lincomycin biosynthesis Transcriptional regulation Aspartate metabolism
- Tandem Multimer Expression and Preparation of Hypoglycemic Peptide MC6 from Momordica charantia in Escherichia coli被引量：14收藏
- 作者：Wang, Fu-Jun Song, Huai-Lei Wang, Xiao-Meng Zhang, Wen-Ji Wang, Bi-Lian Zhao, Jian Hu, Zhi-Bi
- 机构：E China Univ Sci & Technol;Shanghai Univ Chinese Tradit Med;Shanghai Jiao Tong Univ
- 来源：APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY 2012
- 关键词：Momordica charantia Hypoglycemic peptide MC6 Multimer Isocaudamer
- Enhancing tumor-specific intracellular delivering efficiency of cell-penetrating peptide by fusion with a peptide targeting to EGFR被引量：13收藏
- 作者：Long The Nguyen Yang, Xu-Zhong Du, Xuan Wang, Jia-Wei Zhang, Rui Zhao, Jian Wang, Fu-Jun Dong, Yang Li, Peng-Fei
- 机构：E China Univ Sci & Technol;Zhejiang Reachall Pharmaceut Co Ltd;Shanghai Univ Tradit Chinese Med
- 来源：AMINO ACIDS 2015
- 关键词：Cell-penetrating peptide Tumor-homing peptide Targeted drug delivery Growth factor
