成果/Result
- Characteristics and mechanisms of resorption in lumbar disc herniation被引量：106收藏
- 作者：Yu, Pengfei Mao, Feng Chen, Jingyun Ma, Xiaoying Dai, Yuxiang Liu, Guanhong Dai, Feng Liu, Jingtao
- 机构：Nanjing Univ Chinese Med;Kunshan Integrated TCM & Western Med Hosp;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：ARTHRITIS RESEARCH & THERAPY 2022
- 关键词：Lumbar disc herniation Autoimmune response Inflammation Macrophages Angiogenesis
- ABA-responsive transcription factor bZIP1 is involved in modulating biosynthesis of phenolic acids and tanshinones in Salvia miltiorrhiza被引量：96收藏
- 作者：Deng, Changping Shi, Min Fu, Rong Zhang, Yi Wang, Qiang Zhou, Yang Wang, Yao Ma, Xingyuan Kai, Guoyin
- 机构：Zhejiang Chinese Med Univ;East China Univ Sci & Technol;Shanghai Normal Univ
- 来源：JOURNAL OF EXPERIMENTAL BOTANY 2020
- 关键词：Biosynthesis phenolic acids Salvia miltiorrhiza tanshinones transcriptional regulation transcription factor
- SmMYB2 promotes salvianolic acid biosynthesis in the medicinal herb Salvia miltiorrhiza被引量：94收藏
- 作者：Deng, Changping Wang, Yao Huang, Fenfen Lu, Sunjie Zhao, Limei Ma, Xingyuan Kai, Guoyin
- 机构：Zhejiang Chinese Med Univ;East China Univ Sci & Technol;Shanghai Normal Univ
- 来源：JOURNAL OF INTEGRATIVE PLANT BIOLOGY 2020
- 关键词：anthocyanin rosmarinic acid salvianolic acid B Salvia miltiorrhiza SmMYB2
- Rhodamine 6G conjugated-quantum dots used for highly sensitive and selective ratiometric fluorescence sensor of glutathione被引量：62收藏
- 作者：Gui, Rijun An, Xueqin Su, Hongjuan Shen, Weiguo Zhu, Linyong Ma, Xingyuan Chen, Zhiyun Wang, Xiaoyong
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol;E China Univ Sci & Technol
- 来源：TALANTA 2012
- 关键词：Quantum dots Fluorescence Glutathione Ratiometric sensor
- Functionalization of single-walled carbon nanotubes enables efficient intracellular delivery of siRNA targeting MDM2 to inhibit breast cancer cells growth被引量：61收藏
- 作者：Chen, Hailong Ma, Xingyuan Li, Zhi Shi, Qiaoyun Zheng, Wenyun Liu, Yang Wang, Ping
- 机构：E China Univ Sci & Technol;Natl Univ Singapore;E China Univ Sci & Technol
- 来源：BIOMEDICINE & PHARMACOTHERAPY 2012
- 关键词：Functionalized SWNTs Delivery of siRNA MDM2 Breast cancer cells
- Development of Novel Lignin-Based Targeted Polymeric Nanoparticle Platform for Efficient Delivery of Anticancer Drugs被引量：51收藏
- 作者：Liu, Kefeng Zheng, Dan Lei, Hantian Liu, Jing Lei, Jiandu Wang, Luying Ma, Xingyuan
- 机构：Beijing Forestry Univ;East China Univ Sci & Technol
- 来源：ACS BIOMATERIALS SCIENCE & ENGINEERING 2018
- 关键词：polymeric nanoparticle drug delivery lignin renewable biopolymer self-assembly hydroxyl camptothecin
- Biodegradation of benzene homologues in contaminated sediment of the East China Sea被引量：43收藏
- 作者：Li, Hui Zhang, Qian Wang, Xiao-Li Ma, Xing-Yuan Lin, Kuang-Fei Liu, Yong-Di Gu, Ji-Dong Lu, Shu-Guang Shi, Lei Lu, Qiang Shen, Ting-Ting
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol;Univ Hong Kong
- 来源：BIORESOURCE TECHNOLOGY 2012
- 关键词：BTEX Biodegradation Bacterial community Metabolic pathway Compatible solutes
- Effects of over-expression of glycerol dehydrogenase and 1,3-propanediol oxidoreductase on bioconversion of glycerol into 1,3-propandediol by Klebsiella pneumoniae under micro-aerobic conditions被引量：42收藏
- 作者：Zhao, Li Zheng, Yu Ma, Xingyuan Wei, Dongzhi
- 机构：E China Univ Sci & Technol
- 来源：BIOPROCESS AND BIOSYSTEMS ENGINEERING 2009
- 关键词：1,3-Propanediol 1,3-Propanediol oxidoreductase Glycerol dehydrogenase Klebsiella pneumoniae Micro-aerobic conditions
- Mutant library construction in directed molecular evolution被引量：40收藏
- 作者：Wang, Tian-Wen Zhu, Hu Ma, Xing-Yuan Zhang, Ting Ma, Yu-Shu Wei, Dong-Zhi
- 机构：E China Univ Sci & Technol
- 来源：MOLECULAR BIOTECHNOLOGY 2006
- 关键词：directed molecular evolution error-prone PCR oligonucleotide-based mutagenesis DNA shuffling mutator strain somatic hypermutation
- MiR-212-3p inhibits LPS-induced inflammatory response through targeting HMGB1 in murine macrophages被引量：39收藏
- 作者：Chen, Weiwei Ma, Xiaoying Zhang, Peng Li, Qifeng Liang, Xin Liu, Jianwen
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Shanghai Jiao Tong Univ
- 来源：EXPERIMENTAL CELL RESEARCH 2017
- 关键词：MiR-212-3p HMGB1 Inflammatory response MAPKs
- PEGylated-PLGA Nanoparticles Coated with pH-Responsive Tannic Acid-Fe(III) Complexes for Reduced Premature Doxorubicin Release and Enhanced Targeting in Breast Cancer被引量：38收藏
- 作者：Hu, Fabiao Zhang, Ruihuan Guo, Wei Yan, Ting He, Xiujuan Hu, Fengzhi Ren, Fuzheng Ma, Xingyuan Lei, Jiandu Zheng, Wenyun
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Beijing Forestry Univ
- 来源：MOLECULAR PHARMACEUTICS 2021
- 关键词：TPLGA NPs premature release effect inhibition chemotherapy drug delivery tumor tissue targeting
- IL-8/CXCR2 mediates tropism of human bone marrow-derived mesenchymal stem cells toward CD133+/CD44+Colon cancer stem cells被引量：36收藏
- 作者：Ma, Xiaoying Chen, Jingyun Liu, Jiajun Xu, Baixue Liang, Xinyu Yang, Xiaotong Feng, Yun Liang, Xin Liu, Jianwen
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Shanghai Jiao Tong Univ
- 来源：JOURNAL OF CELLULAR PHYSIOLOGY 2021
- 关键词：colon cancer stem cell CXCR2 inhibitor IL-8 peptide inhibitor mesenchymal stem cell stemness tropism
- CqToll participates in antiviral response against white spot syndrome virus via induction of anti-lipopolysaccharide factor in red claw crayfish Cherax quadricarinatus被引量：32收藏
- 作者：Li, Yan-yao Chen, Xiao-xiao Lin, Feng-yu Chen, Qiu-fan Ma, Xing-yuan Liu, Hai-peng
- 机构：Xiamen Univ;East China Univ Sci & Technol
- 来源：DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY 2017
- 关键词：Toll receptor Cherax quadricarinatus White spot syndrome virus Anti-lipopolysacchride factor
- Inhibition of airway remodeling and inflammation by isoforskolin in PDGF-induced rat ASMCs and OVA-induced rat asthma model被引量：29收藏
- 作者：Liang, Xin Wang, Jingjing Chen, Weiwei Ma, Xiaoying Wang, Yaqin Nagao, Norio Weng, Weiyu Huang, Jianming Liu, Jianwen
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Fudan Univ;Prefectural Univ Hiroshima
- 来源：BIOMEDICINE & PHARMACOTHERAPY 2017
- 关键词：Isoforskolin Airway remodeling Airway inflammation TGF-beta 1 IL-10/IL-1 beta
- Feature article: Mesenchymal stem cells maintain the stemness of colon cancer stem cells via interleukin-8/mitogen-activated protein kinase signaling pathway被引量：28收藏
- 作者：Ma, Xiaoying Liu, Jiajun Yang, Xiaotong Fang, Kai Zheng, Peiyong Liang, Xin Liu, Jianwen
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Shanghai Univ Tradit Chinese Med
- 来源：EXPERIMENTAL BIOLOGY AND MEDICINE 2020
- 关键词：Mesenchymal stem cell colon cancer stem cell stemness interleukin-8 mitogen-activated protein kinase
- Screening of an anti-inflammatory peptide from Hydrophis cyanocinctus and analysis of its activities and mechanism in DSS-induced acute colitis被引量：27收藏
- 作者：Zheng, Zengjie Jiang, Hailong Huang, Yan Wang, Jie Qiu, Lei Hu, Zhenlin Ma, Xingyuan Lu, Yiming
- 机构：E China Univ Sci & Technol;Second Mil Med Univ
- 来源：SCIENTIFIC REPORTS 2016
- Cannabidiol Effectively Promoted Cell Death in Bladder Cancer and the Improved Intravesical Adhesion Drugs Delivery Strategy Could Be Better Used for Treatment被引量：24收藏
- 作者：Chen, Shanshan Deng, Changping Zheng, Wenyun Li, Shihui Liu, Yuping Zhang, Tong Zhang, Chen Fu, Yunhui Miao, Hui Ren, Fuzheng Ma, Xingyuan
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：PHARMACEUTICS 2021
- 关键词：cannabidiol (CBD) bladder cancer (BC) RNA sequencing PI3K Akt chitosan CBD-loaded PLGA
- The effect and mechanism of erianin on the reversal of oxaliplatin resistance in human colon cancer cells被引量：23收藏
- 作者：Su, Chang Liu, Shaoqun Ma, Xiaoying Liu, Jiajun Liu, Jianwen Lei, Ming Cao, Yiou
- 机构：Fudan Univ;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：CELL BIOLOGY INTERNATIONAL 2021
- 关键词：colon cancer drug resistance erianin oxaliplatin P-gp STAT3
- A novel liposome-polymer hybrid nanoparticles delivering a multi-epitope self-replication DNA vaccine and its preliminary immune evaluation in experimental animals被引量：23收藏
- 作者：Zhao, Zhangting Ma, Xingyuan Zhang, Ruihuan Hu, Fabiao Zhang, Tong Liu, Yuping Han, Myong Hun You, Fang Yang, Yi Zheng, Wenyun
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;KIM IL SUNG Univ;Natl Univ Singapore;SinGENE Biotech Pte Ltd
- 来源：NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE 2021
- 关键词：DNA vaccine Liposome-polymer hybrid nanoparticles Delivery Immune evaluation Infectious diseases
- High-level expression, purification and pro-apoptosis activity of HIV-TAT-survivin (T34A) mutant to cancer cells in vitro被引量：23收藏
- 作者：Ma, Xingyuan Zheng, Wenyun Wei, Dongzhi Ma, Yushu Wang, Tianwen Wang, Jinzhi Liu, Qinghai Yang, Shengli
- 机构：E China Univ Sci & Technol;Shenyang Pharmaceut Univ;Chinese Acad Sci
- 来源：JOURNAL OF BIOTECHNOLOGY 2006
- 关键词：TAT-survivin (T34A) mutant high-level expression and purification pro-apoptosis
- miR-139-5p reverses stemness maintenance and metastasis of colon cancer stem-like cells by targeting E2-2被引量：23收藏
- 作者：Ma, Xiaoying Liu, Jiajun Li, Jiyu Li, Yueqi Van Minh Le Li, Shaoyu Liang, Xin Li, Lingshuang Liu, Jianwen
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Tongji Univ;Natl Inst Med Mat;Xinjiang Med Univ
- 来源：JOURNAL OF CELLULAR PHYSIOLOGY 2019
- 关键词：CD133+/CD44+ colon cancer EMT metastasis stemness
- Hsa_circ_0087352 promotes the inflammatory response of macrophages in abdominal aortic aneurysm by adsorbing hsa-miR-149-5p被引量：22收藏
- 作者：Ma, Xiaoying Xu, Jinfang Lu, Qingsheng Feng, Xiang Liu, Jiajun Cui, Chaoyi Song, Chao
- 机构：Shanghai Changhai Hosp;East China Univ Sci & Technol;East China Univ Sci & Technol;Second Mil Med Univ;Shanghai Jiao Tong Univ
- 来源：INTERNATIONAL IMMUNOPHARMACOLOGY 2022
- 关键词：Abdominal aortic aneurysm Circular RNA Macrophage Inflammation ERK/NF/kappa B
- RETRACTED: Effect of hCMSCs and liraglutide combination in ALI through cAMP/PKAc/β-catenin signaling pathway (Retracted article. See vol. 14, 2023)被引量：22收藏
- 作者：Feng, Yun Wang, Linlin Ma, Xiaoying Yang, Xiaotong Don, Ocholi Chen, Xiaoyan Qu, Jieming Song, Yuanlin
- 机构：Fudan Univ;Shanghai Jiao Tong Univ;Shanghai Jiao Tong Univ;Shanghai Resp Res Inst;East China Univ Sci & Technol
- 来源：STEM CELL RESEARCH & THERAPY 2020
- 关键词：ALI ARDS Mesenchymal stem cells Liraglutide Combination therapy
- The Detrimental Role of Intraluminal Thrombus Outweighs Protective Advantage in Abdominal Aortic Aneurysm Pathogenesis: The Implications for the Anti-Platelet Therapy被引量：22收藏
- 作者：Ma, Xiaoying Xia, Shibo Liu, Guangqin Song, Chao
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;St Michaels Hosp;Shanghai Changhai Hosp
- 来源：BIOMOLECULES 2022
- 关键词：abdominal aortic aneurysms intraluminal thrombus vascular biology anti-platelet drugs aspirin
- Discovery and optimization of 4-anilinoquinazoline derivatives spanning ATP binding site and allosteric site as effective EGFR-C797S inhibitors被引量：20收藏
- 作者：Dou, Dou Wang, Jie Qiao, Yunjin Wumaier, Gulinuer Sha, Wenjie Li, Wenjie Mei, Wenyi Yang, Tingyuan Zhang, Chen He, Huan Wang, Caolin Chu, Linna Sun, Baihui Su, Rongrong Ma, Xiangyu Gong, Mengdie Xie, Lijuan Jiang, Wenzhe Diao, Yanyan Zhu, Lili Zhao, Zhenjiang Chen, Zhuo Xu, Yufang Li, Shengqing Li, Honglin
- 机构：East China Univ Sci & Technol;Fudan Univ
- 来源：EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 2022
- 关键词：4-Anilinoquinazoline Non-small cell lung cancer (NSCLC) Epidermal growth factor receptor (EGFR) Kinase inhibitor Anti-proliferative activity
- Overview of Regulatory Strategies and Molecular Elements in Metabolic Engineering of Bacteria被引量：19收藏
- 作者：Wang, Tianwen Ma, Xingyuan Du, Guocheng Chen, Jian
- 机构：E China Univ Sci & Technol;Jiangnan Univ
- 来源：MOLECULAR BIOTECHNOLOGY 2012
- 关键词：Metabolic pathway Metabolic engineering Riboswitch Intergenic region Rational design Directed evolution
- One-step production of 2,3-butanediol from starch by secretory over-expression of amylase in Klebsiella pneumoniae被引量：19收藏
- 作者：Zheng, Yu Zhang, Haiyi Zhao, Li Wei, Liujing Ma, Xingyuan Wei, Dongzhi
- 机构：E China Univ Sci & Technol
- 来源：JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY 2008
- 关键词：alpha-amylase 2,3-butanediol Klebsiella pneumoniae secretory over-expression starch
- Available methods for assembling expression cassettes for synthetic biology被引量：19收藏
- 作者：Wang, Tianwen Ma, Xingyuan Zhu, Hu Li, Aitao Du, Guocheng Chen, Jian
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol;Jiangnan Univ;China Univ Petr E China
- 来源：APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 2012
- 关键词：Synthetic biology Simultaneous expression Pathway construction Yeast recombination Cre-loxP site-specific recombination Acembl system
- Over-expression of glycerol dehydrogenase and 1,3-propanediol oxidoreductase in Klebsiella pneumoniae and their effects on conversion of glycerol into 1,3-propanediol in resting cell system被引量：17收藏
- 作者：Zhao, Li Ma, Xingyuan Zheng, Yu Zhang, Jianguo Wei, Guodong Wei, Dongzhi
- 机构：E China Univ Sci & Technol
- 来源：JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY 2009
- 关键词：1,3-propanediol 1,3-propanediol oxidoreductase glycerol dehydrogenase resting cell system Klebsiella pneumoniae
- Designing and constructing a phage display synthesized single domain antibodies library based on camel VHHs frame for screening and identifying humanized TNF-α-specific nanobody被引量：17收藏
- 作者：Nie, Jifan Ma, Xingyuan Hu, Fabiao Miao, Hui Feng, Xin Zhang, Peiwen Han, Myong Hun You, Fang Yang, Yi Zhang, Wenlian Zheng, Wenyun
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Kim Il Sung Univ;Natl Univ Singapore;SinGENE Biotech Pte Ltd
- 来源：BIOMEDICINE & PHARMACOTHERAPY 2021
- 关键词：Single domain antibodies Phage display library Designing and constructing Humanized TNF-alpha-specific Nb Screening and identifyin
