成果/Result
- Genome Sequence of the Versatile Fish Pathogen Edwardsiella tarda Provides Insights into its Adaptation to Broad Host Ranges and Intracellular Niches被引量：208收藏
- 作者：Wang, Qiyao Yang, Minjun Xiao, Jingfan Wu, Haizhen Wang, Xin Lv, Yuanzhi Xu, Lili Zheng, Huajun Wang, Shengyue Zhao, Guoping Liu, Qin Zhang, Yuanxing
- 机构：
- 来源：PLOS ONE 2009
- The Bacterial T6SS Effector EvpP Prevents NLRP3 Inflammasome Activation by Inhibiting the Ca2+-Dependent MAPK-Jnk Pathway被引量：140收藏
- 作者：Chen, Hao Yang, Dahai Han, Fajun Tan, Jinchao Zhang, Lingzhi Xiao, Jingfan Zhang, Yuanxing Liu, Qin
- 机构：East China Univ Sci & Technol;Shanghai Engn Res Ctr Maricultured Anim Vaccines;Shanghai Collaborat Innovat Ctr Biomfg Technol
- 来源：CELL HOST & MICROBE 2017
- Phylogenomics characterization of a highly virulent Edwardsiella strain ET080813T encoding two distinct T3SS and three T6SS gene clusters: Propose a novel species as Edwardsiella anguillarum sp nov.被引量：126收藏
- 作者：Shao, Shuai Lai, Qiliang Liu, Qin Wu, Haizhen Xiao, Jingfan Shao, Zongze Wang, Qiyao Zhang, Yuanxing
- 机构：E China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol;State Key Lab Breeding Base Marine Genet Resource;SOA;Key Lab Marine Genet Resources Fujian Prov
- 来源：SYSTEMATIC AND APPLIED MICROBIOLOGY 2015
- 关键词：Edwardsiella anguillarum sp nov. Taxonomy MLST DOH Phylogenomics
- Isolation and identification of fish pathogen Edwardsiella tarda from mariculture in China被引量：119收藏
- 作者：Xiao, Jingfan Wang, Qiyao Liu, Qin Wang, Xin Liu, Huan Zhang, Yuanxing
- 机构：E China Univ Sci & Technol
- 来源：AQUACULTURE RESEARCH 2008
- 关键词：antibiotics susceptibility aquaculture chloramphenicol resistance Edwardsiella tarda pathogenicity
- Edwardsiella tarda T6SS component evpP is regulated by esrB and iron, and plays essential roles in the invasion of fish被引量：89收藏
- 作者：Wang, Xin Wang, Qiyao Xiao, Jingfan Liu, Qin Wu, Haizhen Xu, Lili Zhang, Yuanxing
- 机构：E China Univ Sci & Technol
- 来源：FISH & SHELLFISH IMMUNOLOGY 2009
- 关键词：Edwardsiella tarda evpP esrB Iron Invasion
- Edwardsiella Comparative Phylogenomics Reveal the New Intra/Inter-Species Taxonomic Relationships, Virulence Evolution and Niche Adaptation Mechanisms被引量：86收藏
- 作者：Yang, Minjun Lv, Yuanzhi Xiao, Jingfan Wu, Haizhen Zheng, Huajun Liu, Qin Zhang, Yuanxing Wang, Qiyao
- 机构：E China Univ Sci & Technol;Chinese Natl Human Genome Ctr Shanghai
- 来源：PLOS ONE 2012
- Upconversion fluorescent strip sensor for rapid determination of Vibrio anguillarum被引量：85收藏
- 作者：Zhao, Peng Wu, Yuanyuan Zhu, Yihua Yang, Xiaoling Jiang, Xin Xiao, Jingfan Zhang, Yuanxing Li, Chunzhong
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol
- 来源：NANOSCALE 2014
- 关键词：Assays - Monoclonal antibodies
- QseBC controls flagellar motility, fimbrial hemagglutination and intracellular virulence in fish pathogen Edwardsiella tarda被引量：78收藏
- 作者：Wang, Xin Wang, Qiyao Yang, Minjun Xiao, Jingfan Liu, Qin Wu, Haizhen Zhang, Yuanxing
- 机构：E China Univ Sci & Technol
- 来源：FISH & SHELLFISH IMMUNOLOGY 2011
- 关键词：Edwardsiella tarda QesBC Motililty Hemagglutination Virulence
- Gene expression profiling in live attenuated Edwardsiella tarda vaccine immunized and challenged zebrafish: Insights into the basic mechanisms of protection seen in immunized fish被引量：71收藏
- 作者：Yang, Dahai Liu, Qin Ni, Chunshan Li, Shuai Wu, Haizhen Wang, Qiyao Xiao, Jinfan Zhang, Yuanxing
- 机构：E China Univ Sci & Technol
- 来源：DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY 2013
- 关键词：Zebrafish Edwardsiella tarda Live attenuated vaccine Immune responses CTLs
- Immune responses of zebrafish (Danio rerio) induced by bath-vaccination with a live attenuated Vibrio anguillarum vaccine candidate被引量：65收藏
- 作者：Zhang, Zhihui Wu, Haizhen Xiao, Jingfan Wang, Qiyao Liu, Qin Zhang, Yuanxing
- 机构：E China Univ Sci & Technol
- 来源：FISH & SHELLFISH IMMUNOLOGY 2012
- 关键词：Bath-vaccination Danio rerio Immunoprotection Live attenuated vaccine Vibrio anguillarum
- Characterization of Edwardsiella tarda rpoS: effect on serum resistance, chondroitinase activity, biofilm formation, and autoinducer synthetases expression被引量：62收藏
- 作者：Xiao, Jingfan Wang, Qiyao Liu, Qin Xu, Lili Wang, Xin Wu, Haizhen Zhang, Yuanxing
- 机构：E China Univ Sci & Technol
- 来源：APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 2009
- 关键词：Edwardsiella tarda Chondroitinase rpoS Virulence Quorum sensing
- RNA-seq liver transcriptome analysis reveals an activated MHC-I pathway and an inhibited MHC-II pathway at the early stage of vaccine immunization in zebrafish被引量：58收藏
- 作者：Yang, Dahai Liu, Qin Yang, Minjun Wu, Haizhen Wang, Qiyao Xiao, Jingfan Zhang, Yuanxing
- 机构：E China Univ Sci & Technol
- 来源：BMC GENOMICS 2012
- Hemolysin EthA in Edwardsiella tarda is essential for fish invasion in vivo and in vitro and regulated by two-component system EsrA-EsrB and nucleoid protein HhaEt被引量：56收藏
- 作者：Wang, Xin Wang, Qiyao Xiao, Jingfan Liu, Qin Wu, Haizhen Zhang, Yuanxing
- 机构：E China Univ Sci & Technol
- 来源：FISH & SHELLFISH IMMUNOLOGY 2010
- 关键词：Edwardsiella tarda Hemolysin EthA esrB hha(Et)
- Systematic mutation analysis of two-component signal transduction systems reveals EsrA-EsrB and PhoP-PhoQ as the major virulence regulators in Edwardsiella tarda被引量：53收藏
- 作者：Lv, Yuanzhi Xiao, Jingfan Liu, Qin Wu, Haizhen Zhang, Yuanxing Wang, Qiyao
- 机构：E China Univ Sci & Technol
- 来源：VETERINARY MICROBIOLOGY 2012
- 关键词：Edwardsiella tarda Two-component system Virulence EsrB PhoP Antimicrobial peptide
- Role of intestinal inflammation in predisposition of Edwardsiella tarda infection in zebrafish (Danio rerio)被引量：51收藏
- 作者：Liu, Xiaohong Chang, Xinyue Wu, Haizhen Xiao, Jingfan Gao, Yuan Zhang, Yuanxing
- 机构：E China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol
- 来源：FISH & SHELLFISH IMMUNOLOGY 2014
- 关键词：Edwardsiella tarda Intestinal inflammation Zebrafish Infection Antimicrobial response
- Edwardsiella tarda mutant disrupted in type III secretion system and chorismic acid synthesis and cured of a plasmid as a live attenuated vaccine in turbot被引量：46收藏
- 作者：Xiao, Jingfan Chen, Tao Liu, Bing Yang, Weizheng Wang, Qiyao Qu, Jiangbo Zhang, Yuanxing
- 机构：E China Univ Sci & Technol;Yantai Dev Zone TianYuan Aquat Prod Co Ltd
- 来源：FISH & SHELLFISH IMMUNOLOGY 2013
- 关键词：Edwardsiella tarda Live attenuated vaccine Turbot
- Flagellin enhances the immunoprotection of formalin-inactivated Edwardsiella tarda vaccine in turbot被引量：39收藏
- 作者：Liu, Xiaohong Zhang, Hua Jiao, Chenglong Liu, Qin Zhang, Yuanxing Xiao, Jingfan
- 机构：East China Univ Sci & Technol;Shanghai Engn Res Ctr Maricultured Anim Vaccines;Shanghai Collaborat Innovat Ctr Biomfg
- 来源：VACCINE 2017
- 关键词：Flagellin Vaccine Adjuvant Edwardsiella tarda Turbot
- Th17-like immune response in fish mucosal tissues after administration of live attenuated Vibrio anguillarum via different vaccination routes被引量：35收藏
- 作者：Zhang, Hua Shen, Binbing Wu, Haizhen Gao, Liang Liu, Qin Wang, Qiyao Xiao, Jingfan Zhang, Yuanxing
- 机构：E China Univ Sci & Technol
- 来源：FISH & SHELLFISH IMMUNOLOGY 2014
- 关键词：Vibrio anguillarum Bath vaccination Injection vaccination Th17 Mucosal immune response
- Characterization of Edwardsiella tarda waaL: roles in lipopolysaccharide biosynthesis, stress adaptation, and virulence toward fish被引量：32收藏
- 作者：Xu, Lili Wang, Qiyao Xiao, Jingfan Liu, Qin Wang, Xin Chen, Tao Zhang, Yuanxing
- 机构：E China Univ Sci & Technol
- 来源：ARCHIVES OF MICROBIOLOGY 2010
- 关键词：Edwardsiella tarda WaaL Lipopolysaccharide Stress adaption Virulence
- A Bacterial Pathogen Senses Host Mannose to Coordinate Virulence被引量：31收藏
- 作者：Wei, Lifan Qiao, Haoxian Sit, Brandon Yin, Kaiyu Yang, Guanhua Ma, Ruiqing Ma, Jiabao Yang, Chun Yao, Jun Ma, Yue Xiao, Jingfan Liu, Xiaohong Zhang, Yuanxing Waldor, Matthew K. Wang, Qiyao
- 机构：East China Univ Sci & Technol;Qingdao Natl Lab Marine Sci & Technol;Shanghai Engn Res Ctr Maricultured Anim Vaccines;Brigham & Womens Hosp;Harvard Med Sch
- 来源：ISCIENCE 2019
- Transposon insertion sequencing reveals T4SS as the major genetic trait for conjugation transfer of multi-drug resistance pEIB202 from Edwardsiella被引量：25收藏
- 作者：Liu, Yang Gao, Yanan Liu, Xiaohong Liu, Qin Zhang, Yuanxing Wang, Qiyao Xiao, Jingfan
- 机构：East China Univ Sci & Technol;Shanghai Engn Res Ctr Maricultured Anim Vaccines;Shanghai Collaborat Innovat Ctr Biomfg
- 来源：BMC MICROBIOLOGY 2017
- 关键词：Plasmid conjugation Edwardsiella PiSCIcida Tis T4SS RNA-seq EsrB
- A live attenuated combination vaccine evokes effective immune-mediated protection against Edwardsiella tarda and Vibrio anguillarum被引量：24收藏
- 作者：Gao, Yuan Wu, Haizhen Wang, Qiyao Qu, Jiangbo Liu, Qin Xiao, Jingfan Zhang, Yuanxing
- 机构：E China Univ Sci & Technol;Yantai Dev Zone Tian Yuan Aquat Prod Co Ltd;Shanghai Collaborat Innovat Ctr Biomfg Technol
- 来源：VACCINE 2014
- 关键词：Edwardsiella tarda Vibrio anguillarum Live attenuated vaccines Combination vaccine Antigen recognition Processing and presentation
- An effective established biosensor of bifunctional probes-labeled AuNPs combined with LAMP for detection of fish pathogen Streptococcus iniae被引量：23收藏
- 作者：Zhou, Ya Xiao, Jingfan Ma, Xin Wang, Qiyao Zhang, Yuanxing
- 机构：East China Univ Sci & Technol;Shanghai Engn Res Ctr Maricultured Anim Vaccines;Shanghai Collaborat Innovat Ctr Biomfg
- 来源：APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 2018
- 关键词：LAMP Gold nanoparticles Bifunctional probes Streptococcus iniae
- Immune response of turbot (Scophthalmus maximus L.) to a broad spectrum vaccine candidate, recombinant glyceraldehyde-3-phosphate dehydrogenase of Edwardsiella tarda被引量：22收藏
- 作者：Liang, Shunqing Wu, Haizhen Liu, Bing Xiao, Jingfan Wang, Qiyao Zhang, Yuanxing
- 机构：E China Univ Sci & Technol
- 来源：VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY 2012
- 关键词：Edwardsiella tarda Immune response Recombinant GAPDH Turbot
- Iron-Regulated Lysis of Recombinant Escherichia coli in Host Releases Protective Antigen and Confers Biological Containment被引量：21收藏
- 作者：Guan, Lingyu Mu, Wei Champeimont, Jonathan Wang, Qiyao Wu, Haizhen Xiao, Jingfan Lubitz, Werner Zhang, Yuanxing Liu, Qin
- 机构：E China Univ Sci & Technol;Univ Vienna
- 来源：INFECTION AND IMMUNITY 2011
- Immune responses evoked by infection with Vibrio anguillarum in zebrafish bath-vaccinated with a live attenuated strain被引量：20收藏
- 作者：Zhang, Zhihui Wu, Haizhen Xiao, Jingfan Wang, Qiyao Liu, Qin Zhang, Yuanxing
- 机构：E China Univ Sci & Technol
- 来源：VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY 2013
- 关键词：Immune response Bath-vaccination Zebrafish Live attenuated vaccine Infection
- Skin-injured Zebrafish, Danio rerio, are more Susceptible to Vibrio anguillarum Infection被引量：19收藏
- 作者：Liu, Xiaohong Wu, Haizhen Liu, Qin Wang, Qiyao Xiao, Jingfan Zhang, Yuanxing
- 机构：E China Univ Sci & Technol
- 来源：JOURNAL OF THE WORLD AQUACULTURE SOCIETY 2015
- Design and evaluation of an Edwardsiella tarda DNA vaccine co-encoding antigenic and adjuvant peptide被引量：19收藏
- 作者：Liu, Xiaohong Xu, Jinmei Zhang, Hua Liu, Qin Xiao, Jingfan Zhang, Yuanxing
- 机构：East China Univ Sci & Technol;Shanghai Engn Res Ctr Maricultured Anim Vaccines
- 来源：FISH & SHELLFISH IMMUNOLOGY 2016
- 关键词：Edwardsiella tarda DNA vaccine Co-encoding Bicistronic expression system
- The secreted fructose 1,6-bisphosphate aldolase as a broad spectrum vaccine candidate against pathogenic bacteria in aquaculture被引量：19收藏
- 作者：Sun, Zhongyang Shen, Binbing Wu, Haizhen Zhou, Xiangyu Wang, Qiyao Xiao, Jingfan Zhang, Yuanxing
- 机构：E China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol;Shanghai Engn Res Ctr Mariculture Anim Vaccines
- 来源：FISH & SHELLFISH IMMUNOLOGY 2015
- 关键词：FBA Locations Cross-protection Aquatic pathogenic bacteria Broad spectrum vaccine
- Phylogenetic investigation of Edwardsiella tarda with multilocus sequence typing (MLST) and pulsed field gel electrophoresis (PFGE) typing methods被引量：19收藏
- 作者：Yang, Minjun Shao, Shuai Xiao, Jingfan Wang, Qiyao Zhang, Yuanxing
- 机构：E China Univ Sci & Technol
- 来源：AQUACULTURE 2013
- 关键词：Edwardsiella species Genotype Multilocus sequence typing Pulsed-field gel electrophoresis
