成果/Result
- Ectopic Osteogenesis of Macroscopic Tissue Constructs Assembled from Human Mesenchymal Stem Cell-Laden Microcarriers through In Vitro Perfusion Culture被引量：148收藏
- 作者：Chen, Maiqin Zhou, Min Ye, Zhaoyang Zhou, Yan Tan, Wen-Song
- 机构：E China Univ Sci & Technol
- 来源：PLOS ONE 2014
- Fine Tuning Micellar Core-Forming Block of Poly(ethylene glycol)-block-poly(ε-caprolactone) Amphiphilic Copolymers Based on Chemical Modification for the Solubilization and Delivery of Doxorubicin被引量：135收藏
- 作者：Yan, Jinliang Ye, Zhaoyang Chen, Min Liu, Zhanzhan Xiao, Yan Zhang, Yan Zhou, Yan Tan, Wensong Lang, Meidong
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol
- 来源：BIOMACROMOLECULES 2011
- Improved survival of porcine acute liver failure by a bioartificial liver device implanted with induced human functional hepatocytes被引量：107收藏
- 作者：Shi, Xiao-Lei Gao, Yimeng Yan, Yupeng Ma, Hucheng Sun, Lulu Huang, Pengyu Ni, Xuan Zhang, Ludi Zhao, Xin Ren, Haozhen Hu, Dan Zhou, Yan Tian, Feng Ji, Yuan Cheng, Xin Pan, Guoyu Ding, Yi-Tao Hui, Lijian
- 机构：Nanjing Univ;Chinese Acad Sci;ShanghaiTech Univ;Chinese Acad Sci;E China Univ Sci & Technol
- 来源：CELL RESEARCH 2016
- 关键词：acute liver failure functional hepatocytes bioartificial liver
- A modular approach to the engineering of a centimeter-sized bone tissue construct with human amniotic mesenchymal stem cells-laden microcarriers被引量：94收藏
- 作者：Chen, Maiqin Wang, Xiu Ye, Zhaoyang Zhang, Yan Zhou, Yan Tan, Wen-Song
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol
- 来源：BIOMATERIALS 2011
- 关键词：Tissue engineering Modular approach Microcarriers Macrotissue Mesenchymal stem cells Osteogenic differentiation
- Antihypertensive Effects, Molecular Docking Study, and Isothermal Titration Calorimetry Assay of Angiotensin I-Converting Enzyme Inhibitory Peptides from Chlorella vulgaris被引量：87收藏
- 作者：Xie, Jingli Chen, Xujun Wu, Junjie Zhang, Yanyan Zhou, Yan Zhang, Lujia Tang, Ya-Jie Wei, Dongzhi
- 机构：East China Univ Sci & Technol;Hubei Univ Technol;Shanghai Business Sch;SCICB
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2018
- 关键词：Chlorella vulgaris ACE inhibitory peptides anti hypertensive activity molecular docking isothermal titration calorimetry
- Myocardial regeneration: Roles of stem cells and hydrogels被引量：75收藏
- 作者：Ye, Zhaoyang Zhou, Yan Cai, Haibo Tan, Wensong
- 机构：E China Univ Sci & Technol
- 来源：ADVANCED DRUG DELIVERY REVIEWS 2011
- 关键词：Myocardial regeneration Cell therapy Tissue engineering Stem cells Hydrogels
- A combinatorial variation in surface chemistry and pore size of three-dimensional porous poly(ε-caprolactone) scaffolds modulates the behaviors of mesenchymal stem cells被引量：62收藏
- 作者：Zhao, Yingdi Tan, Ke Zhou, Yan Ye, Zhaoyang Tan, Wen-Song
- 机构：E China Univ Sci & Technol
- 来源：MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS 2016
- 关键词：Tissue engineering Mesenchymal stem cells Three-dimensional porous scaffolds Surface chemistry Pore size
- Efficient liver repopulation of transplanted hepatocyte prevents cirrhosis in a rat model of hereditary tyrosinemia type I被引量：58收藏
- 作者：Zhang, Ludi Shao, Yanjiao Li, Lu Tian, Feng Cen, Jin Chen, Xiaotao Hu, Dan Zhou, Yan Xie, Weifen Zheng, Yunwen Ji, Yuan Liu, Mingyao Li, Dali Hui, Lijian
- 机构：Chinese Acad Sci;East China Normal Univ;East China Normal Univ;Fudan Univ;East China Univ Sci & Technol
- 来源：SCIENTIFIC REPORTS 2016
- Preparation and characterization of antibacterial polyvinyl alcohol/chitosan sponge and potential applied for wound dressing被引量：51收藏
- 作者：Fan, Yao Lu, Qiaohui Liang, Wencheng Wang, Youchang Zhou, Yan Lang, Meidong
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：EUROPEAN POLYMER JOURNAL 2021
- 关键词：PVA DMAEMA Chitosan Wound dressing Antibacterial
- The effect of gap junction-mediated transfer of miR-200b on osteogenesis and angiogenesis in a co-culture of MSCs and HUVECs被引量：49收藏
- 作者：Fan, Xiaoting Teng, Yi Ye, Zhaoyang Zhou, Yan Tan, Wen-Song
- 机构：East China Univ Sci & Technol
- 来源：JOURNAL OF CELL SCIENCE 2018
- 关键词：Pre-vascularized bone Mesenchymal stem cell Endothelial cell Gap junction miR-200b
- A multifunctional green antibacterial rapid hemostasis composite wound dressing for wound healing被引量：42收藏
- 作者：Liang, Wencheng Lu, Qiaohui Yu, Fan Zhang, Junyong Xiao, Chuang Dou, Xiaoming Zhou, Yan Mo, Xiumei Li, Jun Lang, Meidong
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;Donghua Univ;Tongji Univ
- 来源：BIOMATERIALS SCIENCE 2021
- Lycopene production in recombinant strains of Escherichia coli is improved by knockout of the central carbon metabolism gene coding for glucose-6-phosphate dehydrogenase被引量：41收藏
- 作者：Zhou, Yan Nambou, Komi Wei, Liujing Cao, Jingjing Imanaka, Tadayuki Hua, Qiang
- 机构：E China Univ Sci & Technol
- 来源：BIOTECHNOLOGY LETTERS 2013
- 关键词：Escherichia coli Glucose-6-phosphate dehydrogenase Lycopene MEP pathway
- Synthesis, characterization, fluorescence labeling and cellular internalization of novel amine-functionalized poly(ethylene glycol)-block-poly(ε-caprolactone) amphiphilic block copolymers被引量：37收藏
- 作者：Yan, Jinliang Ye, Zhaoyang Luo, Houyong Chen, Min Zhou, Yan Tan, Wensong Xiao, Yan Zhang, Yan Lang, Meidong
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol
- 来源：POLYMER CHEMISTRY 2011
- Fabrication of three-dimensional poly(ε-caprolactone) scaffolds with hierarchical pore structures for tissue engineering被引量：36收藏
- 作者：Zhang, Qingchun Luo, Houyong Zhang, Yan Zhou, Yan Ye, Zhaoyang Tan, Wensong Lang, Meidong
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol
- 来源：MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS 2013
- 关键词：Poly(epsilon-caprolactone) Scaffolds Pore size Fibroblasts
- Identification of multiple sources of the acidic charge variants in an IgG1 monoclonal antibody被引量：35收藏
- 作者：Miao, Shiwei Xie, Panpan Zou, Mao Fan, Li Liu, Xuping Zhou, Yan Zhao, Liang Ding, Ding Wang, Haibin Tan, Wen-Song
- 机构：East China Univ Sci & Technol;Hisun Pharmaceut Hangzhou Co Ltd
- 来源：APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 2017
- 关键词：mAb IgG1 Acidic charge heterogeneity Deamidation Galactosylation Disulfide bond reduction
- Hypoxia alleviates dexamethasone-induced inhibition of angiogenesis in cocultures of HUVECs and rBMSCs via HIF-1α被引量：35收藏
- 作者：Chai, Miaomiao Gu, Ce Shen, Qihua Liu, Jiaxing Zhou, Yi Jin, Ziyang Xiong, Wanli Zhou, Yan Tan, Wensong
- 机构：East China Univ Sci & Technol
- 来源：STEM CELL RESEARCH & THERAPY 2020
- 关键词：Mesenchymal stem cell Human umbilical vein endothelial cell Angiogenesis Dexamethasone Hypoxia
- Influence of lactic acid on the proliferation, metabolism, and differentiation of rabbit mesenchymal stem cells被引量：34收藏
- 作者：Chen, Ting Zhou, Yan Tan, Wen-Song
- 机构：E China Univ Sci & Technol
- 来源：CELL BIOLOGY AND TOXICOLOGY 2009
- 关键词：Colony-forming units assays Differentiation Lactic acid Mesenchymal stem cells Metabolism Proliferation
- Elucidating the effects of pH shift on IgG1 monoclonal antibody acidic charge variant levels in Chinese hamster ovary cell cultures被引量：33收藏
- 作者：Xie, Panpan Niu, Huijie Chen, Xinning Zhang, Xintao Miao, Shiwei Deng, Xiancun Liu, Xuping Tan, Wen-Song Zhou, Yan Fan, Li
- 机构：East China Univ Sci & Technol;Hisun Pharmaceut Hangzhou Co Ltd
- 来源：APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 2016
- 关键词：Acidic charge variants IgG1 monoclonal antibody Disulfide bond reduction Galactosylation Deamination Liquid chromatography mass spectrometry
- The combined effect of sodium butyrate and low culture temperature on the production, sialylation, and biological activity of an antibody produced in CHO cells被引量：33收藏
- 作者：Chen, Fei Kou, Tianci Fan, Li Zhou, Yan Ye, Zhaoyang Zhao, Liang Tan, Wen-Song
- 机构：E China Univ Sci & Technol
- 来源：BIOTECHNOLOGY AND BIOPROCESS ENGINEERING 2011
- 关键词：CHO cells sodium butyrate low culture temperature sialylation N-glycolylneuraminic acid
- 3D Dynamic Culture of Rabbit Articular Chondrocytes Encapsulated in Alginate Gel Beads Using Spinner Flasks for Cartilage Tissue Regeneration被引量：33收藏
- 作者：Xu, Feiyue Xu, Lei Wang, Qi Ye, Zhaoyang Zhou, Yan Tan, Wen-Song
- 机构：E China Univ Sci & Technol
- 来源：BIOMED RESEARCH INTERNATIONAL 2014
- AICAR, a small chemical molecule, primes osteogenic differentiation of adult mesenchymal stem cells被引量：32收藏
- 作者：Wu, Wei Ye, Zhaoyang Zhou, Yan Tan, Wen-Song
- 机构：E China Univ Sci & Technol
- 来源：INTERNATIONAL JOURNAL OF ARTIFICIAL ORGANS 2011
- 关键词：AICAR Mesenchymal stem cells Differentiation Osteogenesis Small molecule
- Perfusion seeding of collagen-chitosan sponges for dermal tissue engineering被引量：31收藏
- 作者：Ding, Chun-Mei Zhou, Yan He, Yan-Na Tan, Wen-Song
- 机构：E China Univ Sci & Technol
- 来源：PROCESS BIOCHEMISTRY 2008
- 关键词：tissue engineering fibroblast collagen-chitosan sponge cell seeding perfusion cell distribution
- Novel antibacterial cellulose diacetate-based composite 3D scaffold as potential wound dressing被引量：31收藏
- 作者：Liang, Wencheng Jiang, Mingli Zhang, Junyong Dou, Xiaoming Zhou, Yan Jiang, Yun Zhao, Li Lang, Meidong
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;Zhejiang Univ Technol
- 来源：JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY 2021
- 关键词：Cellulose diacetate Electrospinning 3D scaffold Wound dressing
- Dipeptidyl peptidase IV inhibitory peptides from Chlorella vulgaris: in silico gastrointestinal hydrolysis and molecular mechanism被引量：31收藏
- 作者：Zhu, Qiaosha Chen, Xujun Wu, Junjie Zhou, Yan Qian, Yang Fang, Ming Xie, Jingli Wei, Dongzhi
- 机构：East China Univ Sci & Technol;Fudan Univ;SCICB
- 来源：EUROPEAN FOOD RESEARCH AND TECHNOLOGY 2017
- 关键词：Chlorella vulgaris DPP-IV inhibitory peptides In silico hydrolysis Molecular docking
- Fabrication of viable and functional pre-vascularized modular bone tissues by coculturing MSCs and HUVECs on microcarriers in spinner flasks被引量：30收藏
- 作者：Zhang, Songjie Zhou, Min Ye, Zhaoyang Zhou, Yan Tan, Wen-Song
- 机构：East China Univ Sci & Technol
- 来源：BIOTECHNOLOGY JOURNAL 2017
- 关键词：Bone tissue engineering Endothelial cells Mesenchymal stem cells Microcarriers Vascularization
- Modeling and optimization of membrane preparation conditions of the alginate-based microcapsules with response surface methodology被引量：30收藏
- 作者：Ma, Ying Zhang, Ying Zhao, Shan Wang, Yu Wang, Siran Zhou, Yan Li, Na Xie, Hongguo Yu, Weiting Liu, Yang Wang, Wei Ma, Xiaojun
- 机构：Chinese Acad Sci;Chinese Acad Sci;E China Univ Sci & Technol
- 来源：JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A 2012
- 关键词：microencapsulation membrane preparation optimization conditions response surface methodology modeling
- Mesenchymal Stem Cells Reshape and Provoke Proliferation of Articular Chondrocytes by Paracrine Secretion被引量：29收藏
- 作者：Xu, Lei Wu, Yuxi Xiong, Zhimiao Zhou, Yan Ye, Zhaoyang Tan, Wen-Song
- 机构：East China Univ Sci & Technol
- 来源：SCIENTIFIC REPORTS 2016
- Dynamic formation of cellular aggregates of chondrocytes and mesenchymal stem cells in spinner flask被引量：28收藏
- 作者：He, Huimin He, Qing Xu, Feiyue Zhou, Yan Ye, Zhaoyang Tan, Wen-Song
- 机构：East China Univ Sci & Technol
- 来源：CELL PROLIFERATION 2019
- 关键词：aggregation kinetics articular chondrocytes cell aggregation mesenchymal stem cells spinner flask
- Hepatocyte culture on 3D porous scaffolds of PCL/PMCL被引量：27收藏
- 作者：Xiao, Yan Zhou, Miaomiao Zhang, Mi Liu, Wei Zhou, Yan Lang, Meidong
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：COLLOIDS AND SURFACES B-BIOINTERFACES 2019
- 关键词：Poly(epsilon-caprolactone) Porous scaffold Crystalline degree Hepatocyte culture
- Pendant small functional groups on poly(E-caprolactone) substrate modulate adhesion, proliferation and differentiation of human mesenchymal stem cells被引量：26收藏
- 作者：Chen, Min Zhang, Yi Zhou, Yan Zhang, Yan Lang, Meidong Ye, Zhaoyang Tan, Wen-Song
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol
- 来源：COLLOIDS AND SURFACES B-BIOINTERFACES 2015
- 关键词：Poly(epsilon-caprolactone) Small functional groups Mesenchymal stem cells Cell fate Tissue engineering
