成果/Result
- Whole cell microbial transformation in cloud point system被引量：84收藏
- 作者：Wang, Zhilong Xu, Jian-He Chen, Daijie
- 机构： School of Pharmacy; Laboratory of Biocatalysis and Bioprocessing; Shanghai Institutes of Pharmacy Industry
- 来源：Journal of Industrial Microbiology and Biotechnology 2008
- 关键词：Biocompatibility - Nonionic surfactants - Phase separation - Solvent extraction
- Efficient production of (R)-(-)-mandelic acid with highly substrate/product tolerant and enantioselective nitrilase of recombinant Alcaligenes sp.被引量：40收藏
- 作者：Zhang, Zhi-Jun Xu, Jian-He He, Yu-Cai Ouyang, Li-Ming Liu, You-Yan Imanaka, Tadayuki
- 机构： Laboratory of Biocatalysis and Bioprocessing; College of Chemistry and Chemical Engineering; Department of Biotechnology
- 来源：Process Biochemistry 2010
- 关键词：Escherichia coli - Cloning - Enantioselectivity - Organic acids
- Biocatalytic synthesis of (R)-(2)-mandelic acid from racemic mandelonitrile by cetyltrimethylammonium bromidepermeabilized cells of Alcaligenes faecalis ECU0401被引量：39收藏
- 作者：He, Yu-Cai Zhang, Zhi-Jun Xu, Jian-He Liu, You-Yan
- 机构： Laboratory of Biocatalysis and Bioprocessing; College of Chemistry and Chemical Engineering; College of Chemistry and Chemical Engineering
- 来源：Journal of Industrial Microbiology and Biotechnology 2010
- 关键词：Cell immobilization - Enzyme immobilization - Hydrolysis - Organic acids - Radioactive waste vitrification
- Biochemical properties and potential applications of an organic solvent-tolerant lipase isolated from Serratia marcescens ECU1010被引量：38收藏
- 作者：Zhao, Li-Li Xu, Jian-He Zhao, Jian Pan, Jiang Wang, Zhi-Long
- 机构： Laboratory of Biocatalysis and Bioprocessing; School of Pharmacy
- 来源：Process Biochemistry 2008
- 关键词：Bacteria - Chirality - Dimers - Enantiomers - Enzyme activity - Organic solvents
- Cloning and biochemical properties of a highly thermostable and enantioselective nitrilase from Alcaligenes sp. ECU0401 and its potential for (R)-(2)-mandelic acid production被引量：36收藏
- 作者：Zhang, Zhi-Jun Xu, Jian-He He, Yu-Cai Ouyang, Li-Ming Liu, You-Yan
- 机构： Laboratory of Biocatalysis and Bioprocessing; College of Chemistry and Chemical Engineering; College of Chemistry and Chemical Engineering
- 来源：Bioprocess and Biosystems Engineering 2011
- 关键词：Cloning - Escherichia coli - Enantioselectivity - Organic acids - Proteins - Purification
- Efficient production of diltiazem chiral intermediate using immobilized lipase from serratia marcescens被引量：34收藏
- 作者：Zhao, Li-Li Pan, Jiang Xu, Jian-He
- 机构： Laboratory of Biocatalysis and Bioprocessing
- 来源：Biotechnology and Bioprocess Engineering 2010
- 关键词：Enzyme activity - Ethers - Enzyme immobilization - Tanks (containers)
- Immobilization of glycolate oxidase from Medicago falcata on magnetic nanoparticles for application in biosynthesis of glyoxylic acid被引量：34收藏
- 作者：Zhu, Hong Pan, Jiang Hu, Bin Yu, Hui-Lei Xu, Jian-He
- 机构： Laboratory of Biocatalysis and Bioprocessing
- 来源：Journal of Molecular Catalysis B: Enzymatic 2009
- 关键词：Nanomagnetics - Nanoparticles - Fourier transform infrared spectroscopy - Batch reactors - Enzyme immobilization - Enzyme activity - Synthesis (chemical) - Biochemistry - Plants (botany) - Scanning electron microscopy
- Deracemization of aryl secondary alcohols via enantioselective oxidation and stereoselective reduction with tandem whole-cell biocatalysts被引量：33收藏
- 作者：Li, Yun-Long Xu, Jian-He Xu, Yi
- 机构： Laboratory of Biocatalysis and Bioprocessing
- 来源：Journal of Molecular Catalysis B: Enzymatic 2010
- 关键词：Enantioselectivity - Stereoselectivity - Ethanol - Oxidation - Enzymes
- Significant enhancement of (R)-mandelic acid production by relieving substrate inhibition of recombinant nitrilase in toluene-water biphasic system被引量：33收藏
- 作者：Zhang, Zhi-Jun Pan, Jiang Liu, Jun-Feng Xu, Jian-He He, Yu-Cai Liu, You-Yan
- 机构： Laboratory of Biocatalysis and Bioprocessing; College of Chemistry and Chemical Engineering; College of Chemistry and Chemical Engineering
- 来源：Journal of Biotechnology 2011
- 关键词：Cells - Cytology - Enantioselectivity - Escherichia coli - Hydrolysis - Organic acids - Organic solvents - Productivity - Toluene
- Resolution of racemic sulfoxides with high productivity and enantioselectivity by a Rhodococcus sp. strain as an alternative to biooxidation of prochiral sulfides for efficient production of enantiopure sulfoxides被引量：32收藏
- 作者：Li, Ai-Tao Yu, Hui-Lei Pan, Jiang Zhang, Jian-Dong Xu, Jian-He Lin, Guo-Qiang
- 机构： Laboratory of Biocatalysis and Bioprocessing; Shanghai Institute of Organic Chemistry
- 来源：Bioresource Technology 2011
- 关键词：Substrates - Enantioselectivity
- Immobilization of Bacillus subtilis esterase by simple cross-linking for enzymatic resolution of dl-menthyl acetate被引量：31收藏
- 作者：Zheng, Gao-Wei Yu, Hui-Lei Li, Chun-Xiu Pan, Jiang Xu, Jian-He
- 机构： Laboratory of Biocatalysis and Bioprocessing
- 来源：Journal of Molecular Catalysis B: Enzymatic 2011
- 关键词：Bacteriology - Monoterpenes - Nitrogen compounds - Cloning - Esters - Enzyme immobilization
- Isolation of a Bacillus strain producing ketone reductase with high substrate tolerance被引量：31收藏
- 作者：Xie, Yan Xu, Jian-He Xu, Yi
- 机构： Laboratory of Biocatalysis and Bioprocessing
- 来源：Bioresource Technology 2010
- 关键词：Bacteriology - Aromatic compounds - Ethanol - Ketones
- Enzymatic transformation of ginsenoside Rg3 to Rh2 using newly isolated Fusarium proliferatum ECU2042被引量：31收藏
- 作者：Su, Jin-Huan Xu, Jian-He Lu, Wen-Ya Lin, Guo-Qiang
- 机构： Laboratory of Biocatalysis and Bioprocessing; Shanghai Institute of Organic Chemistry; Laboratory of Biocatalysis and Bioprocessing
- 来源：Journal of Molecular Catalysis B: Enzymatic 2006
- 关键词：Biosynthesis - Fermentation - Hydrolysis - pH - Rhodium - Soils
- Isolation and properties of a levo-lactonase from Fusarium proliferatum ECU2002: A robust biocatalyst for production of chiral lactones被引量：31收藏
- 作者：Zhang, Xian Xu, Jian-He Xu, Yi Pan, Jiang
- 机构： Laboratory of Biocatalysis and Bioprocessing
- 来源：Applied Microbiology and Biotechnology 2007
- 关键词：Aldehydes - Bacteria - Concentration (process) - Electrophoresis - Ketones
- Significantly improved asymmetric oxidation of sulfide with resting cells of Rhodococcus sp. in a biphasic system被引量：30收藏
- 作者：Li, Ai-Tao Zhang, Jian-Dong Yu, Hui-Lei Pan, Jiang Xu, Jian-He
- 机构： Laboratory of Biocatalysis and Bioprocessing
- 来源：Process Biochemistry 2011
- 关键词：Oxidation - Enantiomers - Paraffins - Alcohols - Polyols - Solvent extraction
- Overexpression of Serratia marcescens lipase in Escherichia coli for efficient bioresolution of racemic ketoprofen被引量：29收藏
- 作者：Long, Zhang-De Xu, Jian-He Zhao, Li-Li Pan, Jiang Yang, Sheng Hua, Ling
- 机构： Laboratory of Biocatalysis and Bioprocessing; Agricultural College; Institute of Plant Physiology and Ecology; Department of Chemistry
- 来源：Journal of Molecular Catalysis B: Enzymatic 2007
- 关键词：Biocatalysts - Enantioselectivity - Esters - Lipases - Optimization - Substrates - Surface active agents
- Efficient reduction of aromatic ketones with NADPH regeneration by using crude enzyme from Rhodotorula cells and mannitol as cosubstrate被引量：28收藏
- 作者：Yang, Wei Xu, Jian-He Pan, Jiang Xu, Yi Wang, Zhi-Long
- 机构： Laboratory of Biocatalysis and Bioprocessing; School of Pharmacy
- 来源：Biochemical Engineering Journal 2008
- 关键词：Enzymes - Polyols - Aromatic compounds - Drug products
- Efficient production of (S)-naproxen with (R)-substrate recycling using an overexpressed carboxylesterase BsE-NP01被引量：27收藏
- 作者：Liu, Xiang Xu, Jian-He Pan, Jiang Zhao, Jing
- 机构： Laboratory of Biocatalysis and Bioprocessing
- 来源：Applied Biochemistry and Biotechnology 2010
- 关键词：Escherichia coli - Hydrolysis - Bacteriology - Enantiomers - Enzymes - Cloning - Enantioselectivity - Esters
- Preparation of (R)-(-)-mandelic acid and its derivatives from racemates by enantioselective degradation with a newly isolated bacterial strain Alcaligenes sp. ECU0401被引量：27收藏
- 作者：He, Yu-Cai Xu, Jian-He Pan, Jiang Ouyang, Li-Ming Xu, Yi
- 机构： Laboratory of Biocatalysis and Bioprocessing
- 来源：Bioprocess and Biosystems Engineering 2008
- 关键词：Organic acids - Enantiomers - Batch cell culture
- Modified ferric hydroxamate spectrophotometry for assaying glycolic acid from the hydrolysis of glycolonitrile by Rhodococcus sp. CCZU10-1被引量：27收藏
- 作者：He, Yu-Cai Liu, You-Yan Ma, Cui-Luan Xu, Jian-He
- 机构： Laboratory of Biochemical Engineering; College of Chemistry and Chemical Engineering; Laboratory of Biocatalysis and Bioprocessing; Changzhou Kangpu Pharmaceutical Co.
- 来源：Biotechnology and Bioprocess Engineering 2011
- 关键词：High performance liquid chromatography - Hydrolysis
- An efficient bioprocess for enzymatic production of l-menthol with high ratio of substrate to catalyst using whole cells of recombinant E. coli被引量：26收藏
- 作者：Zheng, Gao-Wei Pan, Jiang Yu, Hui-Lei Ngo-Thi, Minh-Thu Li, Chun-Xiu Xu, Jian-He
- 机构： Laboratory of Biocatalysis and Bioprocessing
- 来源：Journal of Biotechnology 2010
- 关键词：Bacteriology - Cloning - Escherichia coli - Monoterpenes - Esters - Cytology - Gene encoding - Catalysis - Enzymes - Loading
- Isolation of Rhodococcus sp. strain ECU0066, a new sulfide monooxygenase-producing strain for asymmetric sulfoxidation被引量：25收藏
- 作者：Li, Ai-Tao Zhang, Jian-Dong Xu, Jian-He Lu, Wen-Ya Lin, Guo-Qiang
- 机构： Laboratory of Biocatalysis and Bioprocessing; Shanghai Institute of Organic Chemistry; Laboratory of Biocatalysis and Bioprocessing
- 来源：Applied and Environmental Microbiology 2009
- 关键词：Sulfur compounds - Enzyme activity
- Properties of a novel β-glucosidase from Fusarium proliferatum ECU2042 that converts ginsenoside Rg3 into Rh2被引量：25收藏
- 作者：Su, Jin-Huan Xu, Jian-He Yu, Hui-Lei He, Yu-Cai Lu, Wen-Ya Lin, Guo-Qiang
- 机构： Laboratory of Biocatalysis and Bioprocessing; Shanghai Institute of Organic Chemistry
- 来源：Journal of Molecular Catalysis B: Enzymatic 2009
- 关键词：Carbohydrates - Electrophoresis - Enzyme activity - Fungi - Hydrolysis
- Identification, purification and characterization of β-glucosidase from apple seed as a novel catalyst for synthesis of O-glucosides被引量：24收藏
- 作者：Yu, Hui-Lei Xu, Jian-He Lu, Wen-Ya Lin, Guo-Qiang
- 机构： Laboratory of Biocatalysis and Bioprocessing; Shanghai Institute of Organic Chemistry
- 来源：Enzyme and Microbial Technology 2007
- 关键词：Catalysts - Fruits - Hydrolysis - Purification - Seed - Synthesis (chemical) - Thermodynamic stability
- Enzymatic Synthesis of Glycosides and Glucuronides被引量：23收藏
- 作者：Scaffidi, Adrian Stick, Robert V. K?en, Vladimír Bojarová, Pavla Lu, Wen-Ya Lin, Guo-Qiang Yu, Hui-Lei Tong, Ai-Ming Xu, Jian-He Chiriví, Cosimo Sagui, Francesca Riva, Sergio Khymenets, Olha Clapés, Pere Parella, Teodor Covas, María-Isabel De la Torre, Rafael Joglar, Jesús Kittelmann, Matthias Oberer, Lukas Aichholz, Reiner Ghisalba, Oreste
- 机构： Chemistry M313; Institute of Microbiology; Laboratory of Biocatalysis and Bioprocessing; Istituto Di Chimica del Riconoscimento Molecolare C.N.R; Pharmacology Research Unit
- 来源：Practical Methods for Biocatalysis and Biotransformations 2009
- 关键词：Sugars - Glycosylation
- Preparation of (S)-mandelic acid from racemate using growing cells of Pseudomonas putida ECU1009 with (R)-mandelate degradation activity被引量：21收藏
- 作者：Huang, Han-Rong Xu, Jian-He
- 机构： Laboratory of Biocatalysis and Bioprocessing
- 来源：Biochemical Engineering Journal 2006
- 关键词：Batch cell culture - Biodegradation - Cells - Optimization - Yeast
- Improving enzymatic production of ginsenoside Rh2 from Rg 3 by using nonionic surfactant被引量：21收藏
- 作者：Su, Jin-Huan Xu, Jian-He Wang, Zhi-Long
- 机构： Laboratory of Biocatalysis and Bioprocessing; School of Pharmacy
- 来源：Applied Biochemistry and Biotechnology 2010
- 关键词：Biocompatibility - Fungi - Enzymatic hydrolysis
- Significant improvement of Serratia marcescens lipase fermentation, by optimizing medium, induction, and oxygen supply被引量：19收藏
- 作者：Long, Zhang-De Xu, Jian-He Pan, Jiang
- 机构： Laboratory of Biocatalysis and Bioprocessing; Rice Research Institute
- 来源：Applied Biochemistry and Biotechnology 2007
- 关键词：Ammonium compounds - Carbon - Dissolved oxygen - Fermentation - Fermenters - Nitrogen - Optimization
- Highly enantioselective hydrolysis of phenyl-1,2-ethanediol cyclic carbonates by newly isolated Bacillus sp. ECU0015被引量：15收藏
- 作者：Chang, Lei Ouyang, Li-Ming Xu, Yi Pan, Jiang Xu, Jian-He
- 机构： Laboratory of Biocatalysis and Bioprocessing
- 来源：Journal of Molecular Catalysis B: Enzymatic 2010
- 关键词：Bacteriology - Carbonates - Enantioselectivity
- Accelerated directed evolution of dye-decolorizing peroxidase using a bacterial extracellular protein secretion system(BENNY)被引量：1收藏
- 作者：Abdulrahman H.A.Alessa Kang Lan Tee David Gonzalez-Perez Hossam E.M.Omar Ali Caroline A.Evans Alex Trevaskis Jian-He Xu Tuck Seng Wong
- 机构：Department of Chemical & Biological Engineering and Advanced Biomanufacturing Centre;Laboratory of Biocatalysis and Bioprocessing
- 来源：生物资源与生物加工(英文) 2019
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