成果/Result
- Highly optically selective and electrochemically active chemosensor for copper (II) based on triazole-linked glucosyl anthraquinone被引量：96收藏
- 作者：Zhang, Yin-Jie He, Xiao-Peng Hu, Min Li, Zhen Shi, Xiao-Xin Chen, Guo-Rong
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol;E China Univ Sci & Technol;CNRS
- 来源：DYES AND PIGMENTS 2011
- 关键词：Copper (II) Chemosensor Triazolyl glycoside Anthraquinone Click reaction Voltammetry
- A thermo-sensitive PLGA-PEG-PLGA hydrogel for sustained release of docetaxel被引量：93收藏
- 作者：Gao, Yuan Ren, Fuzheng Ding, Baoyue Sun, Ningyun Liu, Xiang Ding, Xueying Gao, Shen
- 机构：Second Mil Med Univ;E China Univ Sci & Technol
- 来源：JOURNAL OF DRUG TARGETING 2011
- 关键词：PLGA-PEG-PLGA docetaxel sustained release intratumoral delivery thermo-sensitive hydrogel
- A Short and Practical Synthesis of Oseltamivir Phosphate (Tamiflu) from (-)-Shikimic Acid被引量：89收藏
- 作者：Nie, Liang-Deng Shi, Xiao-Xin Ko, Kwang Hyok Lu, Wei-Dong
- 机构：E China Univ Sci & Technol
- 来源：JOURNAL OF ORGANIC CHEMISTRY 2009
- A novel asymmetric synthesis of oseltamivir phosphate (Tamiflu) from (-)-shikimic acid被引量：61收藏
- 作者：Nie, Liang-Deng Shi, Xiao-Xin
- 机构：E China Univ Sci & Technol
- 来源：TETRAHEDRON-ASYMMETRY 2009
- Highly stereoselective Pictet-Spengler reaction of D-tryptophan methyl ester with piperonal:: convenient syntheses of Cialis (Tadalafil), 12a-epi-Cialis, and their deuterated analogues被引量：46收藏
- 作者：Shi, Xiao-Xin Liu, Shi-Ling Xu, Wei Xu, Yu-Lan
- 机构：E China Univ Sci & Technol
- 来源：TETRAHEDRON-ASYMMETRY 2008
- Expeditious preparation of triazole-linked glycolipids via microwave accelerated click chemistry and their electrochemical and biological assessments被引量：45收藏
- 作者：Song, Shao-Xing Zhang, Hai-Lin Kim, Chol-Guk Sheng, Li He, Xiao-Peng Long, Yi-Tao Li, Jia Chen, Guo-Rong
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol;Chinese Acad Sci;E China Univ Sci & Technol;ENS Cachan
- 来源：TETRAHEDRON 2010
- 关键词：Glycolipid derivatives Microwave-assisted click chemistry EIS measurement Gold surface adsorption Cytotoxicity
- Efficient and Practical One-Pot Conversions of N-Tosyltetrahydroisoquinolines into Isoquinolines and of N-Tosyltetrahydro-β-carbolines into β-Carbolines through Tandem β-Elimination and Aromatization被引量：41收藏
- 作者：Dong, Jing Shi, Xiao-Xin Yan, Jing-Jing Xing, Jing Zhang, Qiang Xiao, Sen
- 机构：E China Univ Sci & Technol
- 来源：EUROPEAN JOURNAL OF ORGANIC CHEMISTRY 2010
- 关键词：Synthetic methods Heterocycles Nitrogen heterocycles Dehydrogenation
- Characteristics of bicalutamide solid dispersions and improvement of the dissolution被引量：41收藏
- 作者：Ren, Fuzheng Jing, Qiufang Tang, Yanhui Shen, Yongjia Chen, Jialei Gao, Feng Cui, Jingbin
- 机构：E China Univ Sci & Technol
- 来源：DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY 2006
- 关键词：bicalutamide solid dispersion PVPK30 dissolution rate amorphous state
- Mild and efficient syntheses of 1-aryl-3,4-dihydroisoquinolines and 1-aryl-3,4-dihydro-β-carbolines via regiospecific β-eliminations of the corresponding N-tosyl-1,2,3,4-tetrahydroisoquinolines and N-tosyl-1,2,3,4-tetrahydro-β-carbolines被引量：39收藏
- 作者：Dong, Jing Shi, Xiao-Xin Xing, Jing Yan, Jing-Jing
- 机构： Department of Pharmaceutical Engineering
- 来源：Synthetic Communications 2012
- 关键词：Potassium hydroxide - Solvents
- Quantitative determination of puerarin in dog plasma by HPLC and study on the relative bioavailability of sustained release tablets被引量：38收藏
- 作者：Ren, Fuzheng Jing, Qiufang Shen, Yongjia Ma, Hongmei Cui, Jingbin
- 机构：E China Univ Sci & Technol
- 来源：JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS 2006
- 关键词：puerarin sustained release tablets Yufengningxin tablets bioavailability HPLC
- A unique and rapid approach toward the efficient development of novel protein tyrosine phosphatase (PTP) inhibitors based on 'clicked' pseudo-glycopeptides被引量：33收藏
- 作者：Yang, Jin-Wei He, Xiao-Peng Li, Cui Gao, Li-Xin Sheng, Li Xie, Juan Shi, Xiao-Xin Tang, Yun Li, Jia Chen, Guo-Rong
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol;Chinese Acad Sci;E China Univ Sci & Technol;CNRS
- 来源：BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 2011
- 关键词：Glycopeptides Click reaction Protein tyrosine phosphatase inhibitor Microwave irradiation Docking simulation
- Inversion of secondary chiral alcohols in toluene with the tunable complex of R3N-R′COOH被引量：32收藏
- 作者：Shi, Xiao-Xin Shen, Chun-Li Yao, Jian-Zhong Nie, Liang-Deng Quan, Na
- 机构：E China Univ Sci & Technol
- 来源：TETRAHEDRON-ASYMMETRY 2010
- Novel monoligated imine-Pd-NHC complexes: extremely active pre-catalysts for Suzuki-Miyaura coupling of aryl chlorides被引量：31收藏
- 作者：Shen, An Ni, Chen Cao, Yu-Cai Zhou, Hui Song, Gong-Hua Ye, Xiao-Feng
- 机构：Shanghai Res Inst Chem Ind;Shanghai Res Inst Chem Ind;E China Univ Sci & Technol
- 来源：TETRAHEDRON LETTERS 2014
- 关键词：NHC-Pd complexes Imine ligands Suzuki-Miyaura coupling Aryl chlorides Low catalyst loadings
- Syntheses of chiral 1,3-disubstituted tetrahydro-β-carbolines via CIAT process: highly stereoselective Pictet-Spengler reaction of D-tryptophan ester hydrochlorides with various aldehydes被引量：30收藏
- 作者：Xiao, Sen Lu, Xia Shi, Xiao-Xin Sun, Yu Liang, Li-Li Yu, Xin-Hong Dong, Jing
- 机构：E China Univ Sci & Technol
- 来源：TETRAHEDRON-ASYMMETRY 2009
- A novel and high-yielding asymmetric synthesis of oseltamivir phosphate (Tamiflu) starting from (-)-shikimic acid被引量：26收藏
- 作者：Nie, Liang-Deng Ding, Wei Shi, Xiao-Xin Quan, Na Lu, Xia
- 机构：E China Univ Sci & Technol
- 来源：TETRAHEDRON-ASYMMETRY 2012
- Efficient and Practical Syntheses of Enantiomerically Pure (S)-(-)-Norcryptostyline I, (S)-(-)-Norcryptostyline II, (R)-(+)-Salsolidine and (S)-(-)-Norlaudanosine via a Resolution-Racemization Method被引量：25收藏
- 作者：Zhu, Ruiheng Xu, Zhangli Ding, Wei Liu, Shiling Shi, Xiaoxin Lu, Xia
- 机构：E China Univ Sci & Technol
- 来源：CHINESE JOURNAL OF CHEMISTRY 2014
- 关键词：tetrahydroisoquinolines norcryptostyline salsolidine norlaudanosine resolution racemization
- Efficient P-Chiral Biaryl Bisphosphorus Ligands for Palladium-Catalyzed Asymmetric Hydrogenation被引量：25收藏
- 作者：Jiang, Wenhao Zhao, Qing Tang, Wenjun
- 机构：East China Univ Sci & Technol;Chinese Acad Sci
- 来源：CHINESE JOURNAL OF CHEMISTRY 2018
- 关键词：biaryl bisphosphorus ligands asymmetric hydrogenation enantioselectivity palladium P-chiral
- Total Syntheses of Eudistomins Y1-Y7 by an Efficient One-Pot Process of Tandem Benzylic Oxidation and Aromatization of 1-Benzyl-3,4-dihydro-β-Carbolines被引量：24收藏
- 作者：Trieu, Tien Ha Dong, Jing Zhang, Qiang Zheng, Bo Meng, Tian-Zhuo Lu, Xia Shi, Xiao-Xin
- 机构：E China Univ Sci & Technol
- 来源：EUROPEAN JOURNAL OF ORGANIC CHEMISTRY 2013
- 关键词：Natural products Alkaloids Total synthesis Nitrogen heterocycles Aromatization
- 丙硫菌唑的合成被引量：22收藏
- 作者：王美娟 廖道华 曾仲武 李超 吴忠信 杨芳 师文娟
- 机构：华东理工大学制药工程系;浙江禾本农药化学有限公司
- 来源：《农药》 2009
- 关键词：丙硫菌唑 1-氯-1-氯乙酰基环丙烷 杀菌剂 合成
- 摘要：以1-氯-1-氯乙酰基环丙烷为起始原料经格式反应、缩合反应、硫的亲电加成反应合成了目标产物丙硫菌唑,缩合反应中用水代替DMF做溶剂,提高了产率,节约了成本。丙硫菌唑的总收率31.1%,含量99.3%。产物经1HNMR、M...
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- Synthesis of tadalafil (Cialis) from L-tryptophan被引量：21收藏
- 作者：Xiao, Sen Shi, Xiao-Xin Xing, Jing Yan, Jing-Jing Liu, Shi-Ling Lu, Wei-Dong
- 机构：E China Univ Sci & Technol
- 来源：TETRAHEDRON-ASYMMETRY 2009
- A Green Chemistry Method for the Regeneration of Carbonyl Compounds from Oximes by Using Cupric Chloride Dihydrate as a Recoverable Promoter for Hydrolysis被引量：20收藏
- 作者：Quan, Na Shi, Xiao-Xin Nie, Liang-Deng Dong, Jing Zhu, Rui-Heng
- 机构：E China Univ Sci & Technol
- 来源：SYNLETT 2011
- 关键词：carbonyl compounds oxime hydrolysis cupric chloride green chemistry
- HPLC determination of anethole trithione and its application to pharmacokinetics in rabbits被引量：20收藏
- 作者：Jing, Qiufang Shen, Yongjia Ren, Fuzheng Chen, Jianming Jiang, Zhiting Peng, Baoliang Leng, Yixin Dong, Jing
- 机构：E China Univ Sci & Technol;Second Mil Med Univ
- 来源：JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS 2006
- 关键词：anetbole trithione tablets self-microemulsifying drug delivery system bioavailability HPLC
- Total Syntheses of (+)-Valiolamine and (-)-1-epi-Valiolamine from Naturally Abundant (-)-Shikimic Acid被引量：20收藏
- 作者：Quan, Na Nie, Liang-Deng Zhu, Rui-Heng Shi, Xiao-Xin Ding, Wei Lu, Xia
- 机构：E China Univ Sci & Technol
- 来源：EUROPEAN JOURNAL OF ORGANIC CHEMISTRY 2013
- 关键词：Total synthesis Drug design Natural products Carbohydrates Inhibitors
- Novel asymmetric synthesis of oseltamivir phosphate (Tamiflu) from (-)-shikimic acid via cyclic sulfite intermediates被引量：20收藏
- 作者：Nie, Liang-Deng Shi, Xiao-Xin Quan, Na Wang, Fei-Feng Lu, Xia
- 机构：E China Univ Sci & Technol
- 来源：TETRAHEDRON-ASYMMETRY 2011
- A novel azide-free asymmetric synthesis of oseltamivir phosphate (Tamiflu) starting from Roche's epoxide被引量：19收藏
- 作者：Nie, Liang-Deng Wang, Fei-Feng Ding, Wei Shi, Xiao-Xin Lu, Xia
- 机构：E China Univ Sci & Technol
- 来源：TETRAHEDRON-ASYMMETRY 2013
- Copper-Catalyzed Benign and Efficient Oxidation of Tetrahydroisoquinolines and Dihydroisoquinolines Using Air as a Clean Oxidant被引量：19收藏
- 作者：Zheng, Bo Trieu, Tien Ha Li, Feng-Lei Zhu, Xing-Liang He, Yun-Gang Fan, Qi-Qi Shi, Xiao-Xin
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：ACS OMEGA 2018
- Practical and highly stereoselective method for the preparation of several chiral arylsulfinamides and arylsulfinates based on the spontaneous crystallization of diastereomerically pure N-benzyl-N-(1-phenylethyl)-arylsulfinamides被引量：18收藏
- 作者：Zhu, Rui-Heng Shi, Xiao-Xin
- 机构：E China Univ Sci & Technol
- 来源：TETRAHEDRON-ASYMMETRY 2011
- Stereoselective synthesis of (+)-valienamine starting from the naturally abundant (-)-shildmic acid被引量：16收藏
- 作者：Ding, Wei Yu, Jiang-Ping Shi, Xiao-Xin Nie, Liang-Deng Quan, Na Li, Feng-Lei
- 机构：E China Univ Sci & Technol
- 来源：TETRAHEDRON-ASYMMETRY 2015
- 关于制药工程专业课程设置的设想被引量：16收藏
- 作者：沈永嘉 卓超
- 机构：华东理工大学制药工程系
- 来源：《化工高等教育》 2002
- 关键词：制药工程专业 课程设置 本科教育
- 摘要：自制药工程这个化工类本科专业的名称出现在教育部本科专业目录中以来,许多高等院校相继设立了这一专业并招收了本科生,截止到2002年4月,国内已有59所院校设立了制药工程专业且此规模仍在扩大,但办学条件参差不齐,无法保证教学...
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- The first highly stereoselective approach to the mitotic kinesin Eg5 inhibitor HR22C16 and its analogues被引量：16收藏
- 作者：Xiao, Sen Shi, Xiao-Xin
- 机构：E China Univ Sci & Technol
- 来源：TETRAHEDRON-ASYMMETRY 2010
