成果/Result
- Influence of High Solid Concentration on Enzymatic Hydrolysis and Fermentation of Steam-Exploded Corn Stover Biomass被引量：148收藏
- 作者：Lu, Yifeng Wang, Yonghong Xu, Guoqian Chu, Ju Zhuang, Yingping Zhang, Siliang
- 机构：E China Univ Sci & Technol
- 来源：APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY 2010
- 关键词：Bioethanol Corn stover High solid concentration Enzymatic hydrolysis Fermentation
- Optimization of cellulase mixture for efficient hydrolysis of steam-exploded corn stover by statistically designed experiments被引量：112收藏
- 作者：Zhou, Jin Wang, Yong-Hong Chu, Ju Luo, Ling-Zhi Zhuang, Ying-Ping Zhang, Si-Liang
- 机构：E China Univ Sci & Technol
- 来源：BIORESOURCE TECHNOLOGY 2009
- 关键词：Cellulase mixture Optimization Steam-exploded corn stover Statistically designed experiments Bioethanol
- Salt stress induced lipid accumulation in heterotrophic culture cells of Chlorella protothecoides: Mechanisms based on the multi-level analysis of oxidative response, key enzyme activity and biochemical alteration被引量：100收藏
- 作者：Wang, Tao Ge, Haiyan Liu, Tingting Tian, Xiwei Wang, Zejian Guo, Meijin Chu, Ju Zhuang, Yingping
- 机构：E China Univ Sci & Technol
- 来源：JOURNAL OF BIOTECHNOLOGY 2016
- 关键词：Chlorella protothecoides Heterotrophic culture Lipid Microalgae ROS Salt stress
- Developing a Computational Framework To Advance Bioprocess Scale-Up被引量：87收藏
- 作者：Wang, Guan Haringa, Cees Noorman, Henk Chu, Ju Zhuang, Yingping
- 机构：East China Univ Sci & Technol ECUST;DSM Biotechnol Ctr;Delft Univ Technol
- 来源：TRENDS IN BIOTECHNOLOGY 2020
- 关键词：Metabolism
- Microbial production of 2,3-butanediol by a surfactant (serrawettin)-deficient mutant of Serratia marcescens H30被引量：87收藏
- 作者：Zhang, Liaoyuan Sun, Jian'an Hao, Yingli Zhu, Jiawen Chu, Ju Wei, Dongzhi Shen, Yaling
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol
- 来源：JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY 2010
- 关键词：2,3-Butanediol Serrawettin W1 synthase Inactivation Serratia marcescens Fed-batch
- Integration of microbial kinetics and fluid dynamics toward model-driven scale-up of industrial bioprocesses被引量：81收藏
- 作者：Wang, Guan Tang, Wenjun Xia, Jianye Chu, Ju Noorman, Henk van Gulik, Walter M.
- 机构： State Key Laboratory of Bioreactor Engineering; DSM Biotechnology Center; Department of Biotechnology
- 来源：Engineering in Life Sciences 2020
- 关键词：Metabolism - Mass transfer - Mixing - Metabolic engineering - Batch data processing - Kinetics - Carbon dioxide
- Metabolic engineering coupled with adaptive evolution strategies for the efficient production of high-quality L-lactic acid by Lactobacillus paracasEI被引量：65收藏
- 作者：Tian, Xiwei Liu, Xuehua Zhang, Yifan Chen, Yang Hang, Haifeng Chu, Ju Zhuang, Yingping
- 机构：East China Univ Sci & Technol
- 来源：BIORESOURCE TECHNOLOGY 2021
- 关键词：Lactobacillus paracasEI Lactic acid CRISPR Cas9 Adaptive evolution Open fermentation
- Fluid dynamics investigation of variant impeller combinations by simulation and fermentation experiment被引量：61收藏
- 作者：Xia, Jian-Ye Wang, Yong-Hong Zhang, Si-Liang Chen, Ning Yin, Peng Zhuang, Ying-Ping Chu, Ju
- 机构：E China Univ Chem Technol
- 来源：BIOCHEMICAL ENGINEERING JOURNAL 2009
- 关键词：Dissolved oxygen Fluid mechanics Gas-liquid mass transfer Mixing Mycelia fermentation Shear environment
- Flow Pattern, Mixing, Gas Hold-Up and Mass Transfer Coefficient of Triple-Impeller Configurations in Stirred Tank Bioreactors被引量：60收藏
- 作者：Xie, Minghui Xia, Jianye Zhou, Zhen Chu, Ju Zhuang, Yingping Zhang, Siliang
- 机构：E China Univ Sci & Technol
- 来源：INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH 2014
- 关键词：Gases - Liquids - Mixing - Pumps - Turbine components - Flow patterns - Mass transfer - Turbomachine blades - Velocity
- Progress in the research of S-adenosyl-L-methionine production被引量：59收藏
- 作者：Chu, Ju Qian, Jiangchao Zhuang, Yingping Zhang, Siliang Li, Yourong
- 机构：E China Univ Sci & Technol
- 来源：APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 2013
- 关键词：S-adenosyl-L-methionine L-Methionine ATP L-Methionine adenosyltransferase Pichia pastoris
- Screening endogenous signal peptides and protEIn folding factors to promote the secretory expression of heterologous protEIns in Pichia pastoris被引量：59收藏
- 作者：Duan, Guangdong Ding, Lumei Wei, Dongsheng Zhou, Hangcheng Chu, Ju Zhang, Siliang Qian, Jiangchao
- 机构：East China Univ Sci & Technol
- 来源：JOURNAL OF BIOTECHNOLOGY 2019
- 关键词：Signal peptides Folding factors Pichia pastoris Heterologous protEIn Secretory expression
- Industrial bioprocess control and optimization in the context of systems biotechnology被引量：56收藏
- 作者：Wang, Yong Chu, Ju Zhuang, Yingping Wang, Yonghong Xia, Jianye Zhang, Siliang
- 机构： State Key Laboratory of Bioreactor Engineering
- 来源：Biotechnology Advances 2009
- Pillar[5]arene-Based Acid-Triggered Supramolecular Porphyrin Photosensitizer for Combating Bacterial Infections and Biofilm Dispersion被引量：55收藏
- 作者：Xia, Lei Tian, Jia Yue, Tao Cao, Hongliang Chu, Ju Cai, Haibo Zhang, Weian
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：ADVANCED HEALTHCARE MATERIALS 2022
- 关键词：antibacterial photodynamic arene porphyrin supramolecular
- Enhancement of phototrophic hydrogen production by Rhodobacter sphaeroides ZX-5 using a novel strategy - shaking and extra-light supplementation approach被引量：52收藏
- 作者：Li, Xu Wang, Yong-Hong Zhang, Si-Liang Chu, Ju Zhang, Ming Huang, Ming-Zhi Zhuang, Ying-Ping
- 机构： State Key Laboratory of Bioreactor Engineering
- 来源：International Journal of Hydrogen Energy 2009
- 关键词：Image enhancement - Production efficiency
- CFD analysis of the turbulent flow in baffled shake flasks被引量：49收藏
- 作者：Li, Chao Xia, Jian-Ye Chu, Ju Wang, Yong-Hong Zhuang, Ying-Ping Zhang, Si-Liang
- 机构：E China Univ Sci & Technol
- 来源：BIOCHEMICAL ENGINEERING JOURNAL 2013
- 关键词：Shake flask Hydrodynamics Mass transfer Mixing Shear force Power consumption
- Application of Euler-Lagrange CFD for quantitative evaluating the effect of shear force on Carthamus tinctorius L. cell in a stirred tank bioreactor被引量：49收藏
- 作者：Liu, Yu Wang, Ze-Jian Xia, Jian-Ye Haringa, Cees Liu, Ya-Ping Chu, Ju Zhuang, Ying-Ping Zhang, Si-Liang
- 机构：East China Univ Sci & Technol;Dalian Pract Biotechnol Co Ltd;Delft Univ Technol
- 来源：BIOCHEMICAL ENGINEERING JOURNAL 2016
- 关键词：Plant cell culture Fluid mechanics Agitation Power consumption C tinctorius L. cell Stress thresholds
- Sustainable biosynthesis of curdlan from orange waste by using Alcaligenes faecalis: A systematically modeled approach被引量：48收藏
- 作者：Mohsin, Ali Sun, Jingyun Khan, Imran Mahmood Hang, Haifeng Tariq, Muhammad Tian, Xiwei Ahmed, Waqas Niazi, Sobia Zhuang, Yingping Chu, Ju Mohsin, Muhammad Zubair Salim-ur-Rehman Guo, Meijin
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Jiangnan Univ;Univ Agr Faisalabad;Univ Agr Faisalabad
- 来源：CARBOHYDRATE POLYMERS 2019
- 关键词：Sustainable biosynthesis Orange peels Kinetics Curdlan Batch culture fermentation
- Power consumption, local and average volumetric mass transfer coefficient in multiple-impeller stirred bioreactors for xanthan gum solutions被引量：48收藏
- 作者：Xie, Ming-hui Xia, Jian-ye Zhou, Zhen Zhou, Guo-zhong Chu, Ju Zhuang, Ying-ping Zhang, Si-liang Noorman, Henk
- 机构：E China Univ Sci & Technol;Wenzhou Great Wall Mixer Design Inst;DSM Biotechnol Ctr
- 来源：CHEMICAL ENGINEERING SCIENCE 2014
- 关键词：Power Mass transfer Xanthan gum Non-Newtonian fluid Impeller combination
- Understanding the effect of forEIgn gene dosage on the physiology of Pichia pastoris by transcriptional analysis of key genes被引量：47收藏
- 作者：Zhu, Taicheng Guo, Meijin Zhuang, Yingping Chu, Ju Zhang, Siliang
- 机构：E China Univ Sci & Technol;Chinese Acad Sci
- 来源：APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 2011
- 关键词：Gene dosage Pichia pastoris Methanol metabolism Cell physiology mRNA quantitative analysis
- Enhancing gluconic acid production by controlling the morphology of Aspergillus niger in submerged fermentation被引量：46收藏
- 作者：Lu, Fei Ping, Kangkang Wen, Ling Zhao, Wei Wang, Zejian Chu, Ju Zhuang, Yingping
- 机构：E China Univ Sci & Technol;Shan Dong Fuyang Biol Technol Co Ltd
- 来源：PROCESS BIOCHEMISTRY 2015
- 关键词：Gluconic acid Aspergillus niger Morphology Oxygen transfer rate Diffusion limitation
- GAP promoter library for fine-tuning of gene expression in Pichia pastoris被引量：45收藏
- 作者：Qin, Xiulin Qian, Jiangchao Yao, Gaofeng Zhuang, Yingping Zhang, Siliang Chu, Ju
- 机构： State Key Laboratory of Bioreactor Engineering
- 来源：Applied and Environmental Microbiology 2011
- 关键词：Transcription - Amino acids - Fluorescence - Enzyme activity
- Combined 13C-assisted metabolomics and metabolic flux analysis reveals the impacts of glutamate on the central metabolism of high β-galactosidase-producing Pichia pastoris被引量：45收藏
- 作者：Liu, Ping Huang, Mingzhi Guo, Menglei Qian, Jiangchao Lin, Weilu Chu, Ju Zhuang, Yingping Zhang, Siliang
- 机构： State Key Laboratory of Bioreactor Engineering
- 来源：Bioresources and Bioprocessing 2016
- 关键词：Gene expression - Physiology - Recombinant protEIns - Yeast
- A two-stage fed-batch heterotrophic culture of Chlorella protothecoides that combined nitrogen depletion with hyperosmotic stress strategy enhanced lipid yield and productivity被引量：45收藏
- 作者：Wang, Tao Tian, Xiwei Liu, Tingting Wang, Zejian Guan, Wenyan Guo, Meijin Chu, Ju Zhuang, Yingping
- 机构：East China Univ Sci & Technol
- 来源：PROCESS BIOCHEMISTRY 2017
- 关键词：Microalgae Lipid Glucose inhibition Hyperosmotic stress Two-stage fed-batch culture
- A 9-pool metabolic structured kinetic model describing days to seconds dynamics of growth and product formation by Penicillium chrysogenum被引量：45收藏
- 作者：Tang, Wenjun Deshmukh, Amit T. Haringa, Cees Wang, Guan van Gulik, Walter van Winden, Wouter Reuss, Matthias Heijnen, Joseph J. Xia, Jianye Chu, Ju Noorman, Henk J.
- 机构：East China Univ Sci & Technol;DSM Biotechnol Ctr;Delft Univ Technol;Univ Stuttgart
- 来源：BIOTECHNOLOGY AND BIOENGINEERING 2017
- 关键词：structured model black box model feast-famine kinetics Penicillium chrysogenum
- High efficient production of recombinant human consensus interferon mutant in high cell density culture of Pichia pastoris using two phases methanol control被引量：45收藏
- 作者：Wu, Dan Chu, Ju Hao, Yu-You Wang, Yong-Hong Zhuang, Ying-Ping Zhang, Si-Liang
- 机构： State Key Laboratory of Bioreactor Engineering
- 来源：Process Biochemistry 2011
- 关键词：Aggregates - Physiology - Methanol - Batch cell culture - Covalent bonds - Growth rate - Quality control - Cell proliferation - Sulfur compounds - Yeast - GlycoprotEIns - Recombinant protEIns
- Enhanced acetoin production by serratia marcescens H32 using statistical optimization and a two-stage agitation speed control strategy被引量：42收藏
- 作者：Sun, Jianan Zhang, Liaoyuan Rao, Ben Han, Yunbin Chu, Ju Zhu, Jiawen Shen, Yaling Wei, Dongzhi
- 机构： State Key Laboratory of Bioreactor Engineering; School of Life Science; Chemical Engineering Research Center
- 来源：Biotechnology and Bioprocess Engineering 2012
- 关键词：Bottles - Speed - Speed control - Productivity
- Kinetic analysis of curdlan production by Alcaligenes faecalis with maltose, sucrose, glucose and fructose as carbon sources被引量：42收藏
- 作者：Zhang, Qin Sun, Jingyun Wang, Zejian Hang, Haifeng Zhao, Wei Zhuang, Yingping Chu, Ju
- 机构： State Key Laboratory of Bioreactor Engineering; Shan Dong Fu Yang Biological Technology Co.
- 来源：Bioresource Technology 2018
- 关键词：Carbon - Rate constants - Fructose - Sugar (sucrose) - Biochemistry - Glucose - Growth kinetics - Fermentation - Maltose - Cell growth
- Real-time and on-line monitoring of ethanol fermentation process by viable cell sensor and electronic nose被引量：42收藏
- 作者：Feng, Yao Tian, Xiwei Chen, Yang Wang, Zeyu Xia, Jianye Qian, Jiangchao Zhuang, Yingping Chu, Ju
- 机构：East China Univ Sci & Technol
- 来源：BIORESOURCES AND BIOPROCESSING 2021
- 关键词：Ethanol On-line Viable cell sensor Electronic nose
- Optimization of l-methionine feeding strategy for improving S-adenosyl-l-methionine production by methionine adenosyltransferase overexpressed Pichia pastoris被引量：39收藏
- 作者：Hu, Hui Qian, Jiangchao Chu, Ju Wang, Yonghong Zhuang, Yingping Zhang, Siliang
- 机构：E China Univ Sci & Technol
- 来源：APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 2009
- 关键词：S-adenosyl-L-methionine Methionine adenosyltransferase L-methionine Pichia pastoris ATP
- Improved vitamin B12 production by step-wise reduction of oxygen uptake rate under dissolved oxygen limiting level during fermentation process被引量：38收藏
- 作者：Wang, Ze-Jian Wang, Hui-Yuan Li, Yong-Liang Chu, Ju Huang, Ming-Zhi Zhuang, Ying-Ping Zhang, Si-Liang
- 机构： State Key Laboratory of Bioreactor Engineering; Shijiazhuang Pharma
- 来源：Bioresource Technology 2010
- 关键词：Fermentation - Bacteria - Biosynthesis - Cell growth - Process control - Oxygen supply - Biochemistry - Growth kinetics
