成果/Result
- Low-dose effects on thyroid disruption in zebrafish by long-term exposure to oxytetracycline被引量：50收藏
- 作者：Yu, Kan Li, Xiaoyong Qiu, Yushu Zeng, Xinxin Yu, Xiaogang Wang, Weiye Yi, Xiaoping Huang, Lisu
- 机构：East China Univ Sci & Technol;Shanghai Jiao Tong Univ;Shanghai Jiao Tong Univ;Shanghai Jiao Tong Univ
- 来源：AQUATIC TOXICOLOGY 2020
- 关键词：Antibiotic exposure Developmental toxicity Thyroid disruption Oxytetracycline in the aquatic environment
- Metabolic characteristics of recombinant Chinese hamster ovary cells expressing glutamine synthetase in presence and absence of glutamine被引量：32收藏
- 作者：Zhang, Fang Sun, Xiangming Yi, Xiaoping Zhang, Yuanxing
- 机构：E China Univ Sci & Technol
- 来源：CYTOTECHNOLOGY 2006
- 关键词：animal cell culture cell metabolism glutamine glutamine synthetase recombinant CHO cell
- Novel scale-up strategy based on three-dimensional shear space for animal cell culture被引量：22收藏
- 作者：Li, Chao Teng, Xiaonuo Peng, Huadong Yi, Xiaoping Zhuang, Yingping Zhang, Siliang Xia, Jianye
- 机构：East China Univ Sci & Technol;Imperial Coll London;Imperial Coll London
- 来源：CHEMICAL ENGINEERING SCIENCE 2020
- 关键词：Shear rate Animal cell culture Scale-up Computational fluid dynamics Stirred tank bioreactor
- Application of semi-supervised convolutional neural network regression model based on data augmentation and process spectral labeling in Raman predictive modeling of cell culture processes被引量：22收藏
- 作者：Min, Rui Wang, Zhi Zhuang, Yingping Yi, Xiaoping
- 机构：East China Univ Sci & Technol
- 来源：BIOCHEMICAL ENGINEERING JOURNAL 2023
- 关键词：Semi -supervised learning Convolutional neural network regression Data augmentation Process spectra labeling
- Gene transcription acceleration: Main cause of hepatitis B surface antigen production improvement by dimethyl sulfoxide in the culture of Chinese hamster ovary cells被引量：19收藏
- 作者：Wang, Wenying Yi, Xiaoping Zhang, Yuanxing
- 机构：E China Univ Sci & Technol
- 来源：BIOTECHNOLOGY AND BIOENGINEERING 2007
- 关键词：cell culture CHO cell dimethyl sulfoxide (DMSO) hepatitis B surface antigen gene transcription
- Long-term low-dose oxytetracycline potentially leads to neurobehavioural changes被引量：14收藏
- 作者：Qiu, Yushu Yu, Kan Yu, Xiaogang Yi, Xiaoping Cai, Kang Li, Huajun Xu, Shanshan Wang, Weiye Huang, Lisu
- 机构：Shanghai Jiao Tong Univ;East China Univ Sci & Technol;Shanghai Jiao Tong Univ;Shanghai Jiao Tong Univ;Fudan Univ
- 来源：ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY 2021
- 关键词：Antibiotic exposure Oxytetracycline in the environment Behaviour change Neurotransmitter Thyroid disruption
- Improvement of Vero cell growth in glutamate-based culture by supplementing ammoniagenic compounds被引量：13收藏
- 作者：Huang, Haiyan Yi, Xiaoping Zhang, Yuanxing
- 机构：E China Univ Sci & Technol
- 来源：PROCESS BIOCHEMISTRY 2006
- 关键词：alanine asparagine glutamate glutamine-free glutamine synthetase Vero cell
- Hydrodynamic investigation of a novel shear-generating device for the measurement of anchorage-dependent cell adhesion intensity被引量：11收藏
- 作者：Wang, Han Xia, Jianye Zheng, Zhiming Zhuang, Ying-Ping Yi, Xiaoping Zhang, Dahe Wang, Peng
- 机构：Chinese Acad Sci;Univ Sci & Technol China;East China Univ Sci & Technol
- 来源：BIOPROCESS AND BIOSYSTEMS ENGINEERING 2018
- 关键词：Animal cell culture Adhesion force Energy dissipation rate Microcarriers Modeling
- Tumor microenvironment responsive multifunctional smart living materials based on engineered bacteria for inducing macrophage polarization to enhance tumor immunotherapy被引量：11收藏
- 作者：Jiang, Ning Zhao, Kui Liu, Chengcheng Zhu, Xiaojuan Huang, Xumeng Yang, Lin Yi, Xiaoping Zhuang, Yingping Ye, Bangce Qian, Jiangchao Huang, Jiaofang
- 机构：East China Univ Sci & Technol ECUST;East China Univ Sci & Technol;Xian Jiao Tong Univ Hlth Sci Ctr;Jiangxi Normal Univ JXNU;East China Univ Sci & Technol
- 来源：CHEMICAL ENGINEERING JOURNAL 2024
- 关键词：Biomaterials Biotechnology Engineered living material Targeted therapy Drug delivery
- Coupling metabolomics analysis and DOE optimization strategy towards enhanced IBDV production by chicken embryo fibroblast DF-1 cells被引量：10收藏
- 作者：Lin, Jia Yi, Xiaoping Zhuang, Yingping
- 机构：East China Univ Sci & Technol
- 来源：JOURNAL OF BIOTECHNOLOGY 2020
- 关键词：DF-1 IBDV Metabolome DOE methodology
- Surface modification of non-woven poly (ethylene terephthalate) fibrous scaffold for improving cell attachment in animal cell culture被引量：10收藏
- 作者：Zhang, Weiyuan Yi, Xiaoping Sun, Xiangming Zhang, Yuanxing
- 机构：E China Univ Chem Technol
- 来源：JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY 2008
- 关键词：chemical modification poly (ethylene terephthalate) hydrophilicity fabric scaffold cell attachment animal cell culture
- Large-scale plasmid preparation for transient gene expression被引量：10收藏
- 作者：Cheng, Lu Sun, Xiangming Yi, Xiaoping Zhang, Yuanxing
- 机构：E China Univ Sci & Technol;Shanghai Kexin Biotech Co Ltd
- 来源：BIOTECHNOLOGY LETTERS 2011
- 关键词：CHO cells Fed-batch Plasmid DNA RNase Transient transfection Ultrafiltration
- Enhanced intracellular accumulation of recombinant HBsAg in CHO cells by dimethyl sulfoxide被引量：10收藏
- 作者：Ma, Zheyong Yi, Xiaoping Zhang, Yuanxing
- 机构：E China Univ Sci & Technol
- 来源：PROCESS BIOCHEMISTRY 2008
- 关键词：cell culture recombinant CHO cell dimethyl sulfoxide HBsAg sucrose gradient analysis intracellular accumulation
- A novel scale-up strategy for cultivation of BHK-21 cells based on similar hydrodynamic environments in the bioreactors被引量：9收藏
- 作者：Teng, Xiaonuo Li, Chao Yi, Xiaoping Zhuang, Yingping
- 机构：East China Univ Sci & Technol
- 来源：BIORESOURCES AND BIOPROCESSING 2021
- 关键词：BHK-21 cells Bioreactor Computational fluid dynamics Hydrodynamic characteristics Scale-up
- Development of a simple and high-yielding fed-batch process for the production of porcine circovirus type 2 virus-like particle subunit vaccine被引量：8收藏
- 作者：Cao, Wenlong Cao, Hui Yi, Xiaoping Zhuang, Yingping
- 机构：East China Univ Sci & Technol;Zhejiang EBVAC Biotech Co Ltd
- 来源：AMB EXPRESS 2019
- 关键词：Virus-like particles Porcine circovirus Subunit vaccine Fed-batch process Baculoviral expression system Feeding "cocktail"
- Limitations in the process of transcription and translation inhibit recombinant human chorionic gonadotropin expression in CHO cells被引量：8收藏
- 作者：Liu, Yang Yi, Xiaoping Zhuang, Yingping Zhang, Siliang
- 机构：E China Univ Sci & Technol
- 来源：JOURNAL OF BIOTECHNOLOGY 2015
- 关键词：Transcription limitation Recombinant protein Mammalian cell culture
- Functional Living Materials for Virus Disinfection Based on Engineered Bacillus subtilis Biofilm by Displaying Viral Affinity Peptides and Expressing Protease被引量：7收藏
- 作者：Zhu, Xiaojuan Chen, Jianshu Luo, Jian Liu, Xue Xu, Yan Chen, Lin Dong, Hao Zhang, Lingfan Yang, Lin Jiang, Nin Huang, Xumeng Mohsin, Ali Yi, Xiaoping Wang, Yonghong Zhuang, Yingping Zhang, Xuehong Zhang, Ke Zhang, Lixin Zhong, Chao Huang, Jiaofang
- 机构：East China Univ Sci & Technol ECUST;Shanghai Inst Biol Prod Co Ltd;Chinese Acad Sci;Ocean Univ China;East China Univ Sci & Technol
- 来源：ADVANCED FUNCTIONAL MATERIALS 2024
- 关键词：Bacillus subtilis biofilm engineered living materials SARS-CoV-2 virus disinfection
- Medium optimization based on comparative metabolomic analysis of chicken embryo fibroblast DF-1 cells被引量：5收藏
- 作者：Lin, Jia Yi, Xiaoping Zhuang, Yingping
- 机构：East China Univ Sci & Technol
- 来源：RSC ADVANCES 2019
- 关键词：Animals - Cell culture - Metabolites - Viruses - Cell proliferation - Disease control
- A study on enhanced O-glycosylation strategy for improved production of recombinant human chorionic gonadotropin in Chinese hamster ovary cells被引量：5收藏
- 作者：Deng, Zhe Yi, Xiaoping Chu, Ju Zhuang, Yingping
- 机构：East China Univ Sci & Technol
- 来源：JOURNAL OF BIOTECHNOLOGY 2019
- 关键词：Recombinant human chorionic gonadotropin CHO cell O-glycosylation GalNAc Ugp2 Galnt1
- Enhancement of hepatitis B surface antigen production by adenosine 5′-monophosphate in culture of recombinant Chinese hamster ovary cells被引量：4收藏
- 作者：Luo, Weiwen Sun, Xiangming Yi, Xiaoping Zhang, Yuanxing
- 机构：E China Univ Sci & Technol
- 来源：JOURNAL OF BIOSCIENCE AND BIOENGINEERING 2005
- 关键词：animal cell culture adenosine 5 '-monophosphate adenosine 5 '-triphosphate Chinese hamster ovary (CHO) cell hepatitis B surface antigen (HBsAg)
- Stable over-expression of the human malate-aspartate NADH shuttle member Aralar I in PK15 cells improves energy metabolism and enhances proliferation of porcine circovirus-2被引量：3收藏
- 作者：Xia, Zhongwu Yi, Xiaoping Zhuang, Yingping
- 机构：E China Univ Sci & Technol
- 来源：RSC ADVANCES 2016
- 关键词：Amino acids - Vaccines - Viruses - Cytology - Metabolism - Physiology
- Effects of osmotic pressure on recombinant BHK cell growth and von willebrand factor (vWF) expression被引量：3收藏
- 作者：Yi, Xiaoping Sun, Xiangming Zhang, Yuanxing
- 机构：E China Univ Sci & Technol
- 来源：PROCESS BIOCHEMISTRY 2004
- 关键词：cell apoptosis cell cycle osmotic pressure recombinant BHK cell cell culture
- Mass cultivation of marine fish Chinook salmon embryo cells in bioreactor with low-serum medium被引量：1收藏
- 作者：Chen, JX Sun, XM Zhang, L Yi, XP Zhang, YX
- 机构：E China Univ Sci & Technol
- 来源：AQUACULTURE 2005
- 关键词：animal cell culture bioreactor CHSE cell marine fish cell
- Transient gene expression of a mouse homolog of Fcε-Fcγ fusion protein for anti-allergic function assay被引量：1收藏
- 作者：Cheng, Lu Sun, Xiangming Yi, Xiaoping Zhang, Yuanxing
- 机构：E China Univ Sci & Technol;Shanghai Fuchun Kexin Biotech Co Ltd
- 来源：PROCESS BIOCHEMISTRY 2011
- 关键词：Anti-allergy fusion protein (AAFP) Transient gene expression CHO cells PCA
- Modeling and Application of Controlled-fed Perfusion Culture of CHO Cells in a Bioreactor被引量：1收藏
- 作者：Teng, X. N. Yi, X. P. Sun, X. M. Zhang, Y. X.
- 机构：E China Univ Sci & Technol
- 来源：CHEMICAL AND BIOCHEMICAL ENGINEERING QUARTERLY 2011
- 关键词：Animal cell culture bioreactor CHO cell controlled-fed perfusion serum-free medium
- Overexpression of glutathione synthetase gene improving redox homeostasis and chicken infectious bursal disease virus propagation in chicken embryo fibroblast DF-1被引量：1收藏
- 作者：Lin, Jia Min, Rui Yi, Xiaoping Zhuang, Yingping
- 机构：East China Univ Sci & Technol ECUST;Fujian Univ Tradit Chinese Med
- 来源：BIORESOURCES AND BIOPROCESSING 2023
- 关键词：Chicken infectious bursal virus Chicken embryonic fibroblasts DF-1 Glutathione Glutathione synthetase
- Improvement of RNAi efficiency by delivering of dsRNA formulated with cell-penetrating disulfide polymer in the fall Armyworm, Spodoptera frugiperda被引量：0收藏
- 作者：Wu, Xu Li, Wen-Mei Xu, Qiang Yi, Xiao-Ping Zhang, Da-He He, Ming-Zhe Ren, Yu-Hong
- 机构：East China Univ Sci & Technol;Suzhou Womei Biol Co Ltd
- 来源：JOURNAL OF INSECT PHYSIOLOGY 2025
- 关键词：Fall armyworm dsRNA Chitin synthase B Methoprene-tolerant CPD Delivery RNAi
- Regulation of the pyruvate metabolism node by monogene and polygene engineering of HEK-293 cells被引量：0收藏
- 作者：Xie, Li Miao, Junqing Li, Xiangchao Yi, Xiaoping Chu, Ju
- 机构：East China Univ Sci & Technol
- 来源：RSC ADVANCES 2019
- 关键词：Metabolic engineering - Cell proliferation - Metabolism - Mammals - Vaccines
- Stress-induced premature senescence in high five cell cultures: a principal factor in cell-density effects被引量：0收藏
- 作者：Min, Rui Zhang, Dahe He, Mingzhe Chen, Jingyuan Yi, Xiaoping Zhuang, Yingping
- 机构：East China Univ Sci & Technol ECUST;Womei Biol Co Ltd
- 来源：BIORESOURCES AND BIOPROCESSING 2024
- 关键词：Cell density effect Transcriptome Proteome Time-series analysis Stress-induced premature senescence Mitochondrial dysfunction
