成果/Result
- Genome Sequence of the Versatile Fish Pathogen Edwardsiella tarda Provides Insights into its Adaptation to Broad Host Ranges and Intracellular Niches被引量：208收藏
- 作者：Wang, Qiyao Yang, Minjun Xiao, Jingfan Wu, Haizhen Wang, Xin Lv, Yuanzhi Xu, Lili Zheng, Huajun Wang, Shengyue Zhao, Guoping Liu, Qin Zhang, Yuanxing
- 机构：
- 来源：PLOS ONE 2009
- Phylogenomics characterization of a highly virulent Edwardsiella strain ET080813T encoding two distinct T3SS and three T6SS gene clusters: Propose a novel species as Edwardsiella anguillarum sp nov.被引量：126收藏
- 作者：Shao, Shuai Lai, Qiliang Liu, Qin Wu, Haizhen Xiao, Jingfan Shao, Zongze Wang, Qiyao Zhang, Yuanxing
- 机构：E China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol;State Key Lab Breeding Base Marine Genet Resource;SOA;Key Lab Marine Genet Resources Fujian Prov
- 来源：SYSTEMATIC AND APPLIED MICROBIOLOGY 2015
- 关键词：Edwardsiella anguillarum sp nov. Taxonomy MLST DOH Phylogenomics
- Edwardsiella tarda T6SS component evpP is regulated by esrB and iron, and plays essential roles in the invasion of fish被引量：89收藏
- 作者：Wang, Xin Wang, Qiyao Xiao, Jingfan Liu, Qin Wu, Haizhen Xu, Lili Zhang, Yuanxing
- 机构：E China Univ Sci & Technol
- 来源：FISH & SHELLFISH IMMUNOLOGY 2009
- 关键词：Edwardsiella tarda evpP esrB Iron Invasion
- Efficient accumulation of high-value bioactive substances by carbon to nitrogen ratio regulation in marine microalgae Porphyridium purpureum被引量：89收藏
- 作者：Li, Shaohua Ji, Liang Chen, Cheng Zhao, Shuxin Sun, Meng Gao, Zhengquan Wu, Haizhen Fan, Jianhua
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Shandong Univ Technol
- 来源：BIORESOURCE TECHNOLOGY 2020
- 关键词：Porphyridium purpureum C/N ratio Phycoerythrin Exopolysaccharides Fatty acids
- Edwardsiella Comparative Phylogenomics Reveal the New Intra/Inter-Species Taxonomic Relationships, Virulence Evolution and Niche Adaptation Mechanisms被引量：86收藏
- 作者：Yang, Minjun Lv, Yuanzhi Xiao, Jingfan Wu, Haizhen Zheng, Huajun Liu, Qin Zhang, Yuanxing Wang, Qiyao
- 机构：E China Univ Sci & Technol;Chinese Natl Human Genome Ctr Shanghai
- 来源：PLOS ONE 2012
- QseBC controls flagellar motility, fimbrial hemagglutination and intracellular virulence in fish pathogen Edwardsiella tarda被引量：78收藏
- 作者：Wang, Xin Wang, Qiyao Yang, Minjun Xiao, Jingfan Liu, Qin Wu, Haizhen Zhang, Yuanxing
- 机构：E China Univ Sci & Technol
- 来源：FISH & SHELLFISH IMMUNOLOGY 2011
- 关键词：Edwardsiella tarda QesBC Motililty Hemagglutination Virulence
- Advances in the production of bioactive substances from marine unicellular microalgae Porphyridium spp.被引量：78收藏
- 作者：Li, Shaohua Ji, Liang Shi, Qianwen Wu, Haizhen Fan, Jianhua
- 机构：East China Univ Sci & Technol;Hainan Univ;East China Univ Sci & Technol
- 来源：BIORESOURCE TECHNOLOGY 2019
- 关键词：Red algae Cultivation Metabolic regulation Application Bioactive compounds
- Resveratrol inhibits hypoxia-induced metastasis potential enhancement by restricting hypoxia-induced factor-1α expression in colon carcinoma cells被引量：74收藏
- 作者：Wu, Hongzhong Liang, Xin Fang, Yishi Qin, Xiaoran Zhang, Yuanxing Liu, Jianwen
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol;Shanghai Chempartner Co Ltd
- 来源：BIOMEDICINE & PHARMACOTHERAPY 2008
- 关键词：Resveratrol Metastasis potential Colon carcinoma cell Hypoxia Hypoxia-induced factor-1 alpha
- Gene expression profiling in live attenuated Edwardsiella tarda vaccine immunized and challenged zebrafish: Insights into the basic mechanisms of protection seen in immunized fish被引量：71收藏
- 作者：Yang, Dahai Liu, Qin Ni, Chunshan Li, Shuai Wu, Haizhen Wang, Qiyao Xiao, Jinfan Zhang, Yuanxing
- 机构：E China Univ Sci & Technol
- 来源：DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY 2013
- 关键词：Zebrafish Edwardsiella tarda Live attenuated vaccine Immune responses CTLs
- Immune responses of zebrafish (Danio rerio) induced by bath-vaccination with a live attenuated Vibrio anguillarum vaccine candidate被引量：65收藏
- 作者：Zhang, Zhihui Wu, Haizhen Xiao, Jingfan Wang, Qiyao Liu, Qin Zhang, Yuanxing
- 机构：E China Univ Sci & Technol
- 来源：FISH & SHELLFISH IMMUNOLOGY 2012
- 关键词：Bath-vaccination Danio rerio Immunoprotection Live attenuated vaccine Vibrio anguillarum
- Characterization of Edwardsiella tarda rpoS: effect on serum resistance, chondroitinase activity, biofilm formation, and autoinducer synthetases expression被引量：62收藏
- 作者：Xiao, Jingfan Wang, Qiyao Liu, Qin Xu, Lili Wang, Xin Wu, Haizhen Zhang, Yuanxing
- 机构：E China Univ Sci & Technol
- 来源：APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 2009
- 关键词：Edwardsiella tarda Chondroitinase rpoS Virulence Quorum sensing
- Effect of Constituents from Fructus Aurantii Immaturus and Radix Paeoniae Alba on Gastrointestinal Movement被引量：60收藏
- 作者：Fang, Yi-Shi Shan, Dong-Mei Liu, Jian-Wen Xu, Wen Li, Chang-Long Wu, Hong-Zhong Ji, Guang
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol;Shanghai Univ Tradit Chinese Med
- 来源：PLANTA MEDICA 2009
- 关键词：Citrus aurantium L. Rutaceae Paeonia lactiflora Pall Paeoniaceae gastrointestinal movement
- Notable mucosal immune responses induced in the intestine of zebrafish (Danio rerio) bath-vaccinated with a live attenuated Vibrio anguillarum vaccine被引量：60收藏
- 作者：Liu, Xiaohong Wu, Haizhen Chang, Xinyue Tang, Yufei Liu, Qin Zhang, Yuanxing
- 机构：E China Univ Sci & Technol
- 来源：FISH & SHELLFISH IMMUNOLOGY 2014
- 关键词：Live attenuated Vibrio anguillarum Zebrafish Bath-vaccination Mucosal immune responses
- Evaluation of Microalgae as Immunostimulants and Recombinant Vaccines for Diseases Prevention and Control in Aquaculture被引量：58收藏
- 作者：Ma, Ke Bao, Qiuwen Wu, Yue Chen, Siwei Zhao, Shuxin Wu, Haizhen Fan, Jianhua
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY 2020
- 关键词：aquaculture industry microalgae immunostimulant oral vaccine polymicrobial infections
- RNA-seq liver transcriptome analysis reveals an activated MHC-I pathway and an inhibited MHC-II pathway at the early stage of vaccine immunization in zebrafish被引量：58收藏
- 作者：Yang, Dahai Liu, Qin Yang, Minjun Wu, Haizhen Wang, Qiyao Xiao, Jingfan Zhang, Yuanxing
- 机构：E China Univ Sci & Technol
- 来源：BMC GENOMICS 2012
- Hemolysin EthA in Edwardsiella tarda is essential for fish invasion in vivo and in vitro and regulated by two-component system EsrA-EsrB and nucleoid protein HhaEt被引量：56收藏
- 作者：Wang, Xin Wang, Qiyao Xiao, Jingfan Liu, Qin Wu, Haizhen Zhang, Yuanxing
- 机构：E China Univ Sci & Technol
- 来源：FISH & SHELLFISH IMMUNOLOGY 2010
- 关键词：Edwardsiella tarda Hemolysin EthA esrB hha(Et)
- Transcriptome Profiling Reveals Th17-Like Immune Responses Induced in Zebrafish Bath-Vaccinated with a Live Attenuated Vibrio anguillarum被引量：54收藏
- 作者：Zhang, Hua Fei, Chao Wu, Haizhen Yang, Minjun Liu, Qin Wang, Qiyao Zhang, Yuanxing
- 机构：E China Univ Sci & Technol
- 来源：PLOS ONE 2013
- Systematic mutation analysis of two-component signal transduction systems reveals EsrA-EsrB and PhoP-PhoQ as the major virulence regulators in Edwardsiella tarda被引量：53收藏
- 作者：Lv, Yuanzhi Xiao, Jingfan Liu, Qin Wu, Haizhen Zhang, Yuanxing Wang, Qiyao
- 机构：E China Univ Sci & Technol
- 来源：VETERINARY MICROBIOLOGY 2012
- 关键词：Edwardsiella tarda Two-component system Virulence EsrB PhoP Antimicrobial peptide
- Role of intestinal inflammation in predisposition of Edwardsiella tarda infection in zebrafish (Danio rerio)被引量：51收藏
- 作者：Liu, Xiaohong Chang, Xinyue Wu, Haizhen Xiao, Jingfan Gao, Yuan Zhang, Yuanxing
- 机构：E China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol
- 来源：FISH & SHELLFISH IMMUNOLOGY 2014
- 关键词：Edwardsiella tarda Intestinal inflammation Zebrafish Infection Antimicrobial response
- Dietary supplementation with microalgae enhances the zebrafish growth performance by modulating immune status and gut microbiota被引量：50收藏
- 作者：Ma, Ke Chen, Siwei Wu, Yue Ma, Yiting Qiao, Haochen Fan, Jianhua Wu, Haizhen
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 2022
- 关键词：Microalgae Zebrafish Growth performance Immune status Gut microbiota
- The Novel Transcriptional Regulator LmbU Promotes Lincomycin Biosynthesis through Regulating Expression of Its Target Genes in Streptomyces lincolnensis被引量：40收藏
- 作者：Hou, Bingbing Lin, Yanwei Wu, Haizhen Guo, Meijin Petkovic, Hrvoje Tao, Liyuan Zhu, Xiaoyu Ye, Jiang Zhang, Huizhan
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Univ Ljubljana
- 来源：JOURNAL OF BACTERIOLOGY 2018
- 关键词：LmbU LmbU homologues Streptomyces cluster-situated regulator lincomycin regulatory protein
- Edwardsiella tarda flagellar protein FlgD: A protective immunogen against edwardsiellosis被引量：38收藏
- 作者：Zhang, Meng Wu, Haizhen Li, Xiaoyong Yang, Minjun Chen, Tao Wang, Qiyao Liu, Qin Zhang, Yuanxing
- 机构：E China Univ Sci & Technol
- 来源：VACCINE 2012
- 关键词：Edwardsiella tarda Flagellar protein FlgD Protective antigen
- Th17-like immune response in fish mucosal tissues after administration of live attenuated Vibrio anguillarum via different vaccination routes被引量：35收藏
- 作者：Zhang, Hua Shen, Binbing Wu, Haizhen Gao, Liang Liu, Qin Wang, Qiyao Xiao, Jingfan Zhang, Yuanxing
- 机构：E China Univ Sci & Technol
- 来源：FISH & SHELLFISH IMMUNOLOGY 2014
- 关键词：Vibrio anguillarum Bath vaccination Injection vaccination Th17 Mucosal immune response
- Efficacy of chitosan oligosaccharide as aquatic adjuvant administrated with a formalin-inactivated Vibrio anguillarum vaccine被引量：34收藏
- 作者：Liu, Xiaohong Zhang, Hua Gao, Yuan Zhang, Yang Wu, Haizhen Zhang, Yuanxing
- 机构：E China Univ Sci & Technol;Shanghai Engn Res Ctr Maricultured Anim Vaccines;Shanghai Collaborat Innovat Ctr Biomfg Technol
- 来源：FISH & SHELLFISH IMMUNOLOGY 2015
- 关键词：Water-soluble adjuvant Chitosan oligosaccharide Formalin-inactivated vaccine Vibrio anguillarum
- Gene cloning and characterization of ferritin H and M subunits from large yellow croaker (PseudoSCIaena crocea)被引量：30收藏
- 作者：Zhang, Xiao Wei, Wei Wu, Haizhen Xu, Hongyan Chang, Kangmei Zhang, Yuanxing
- 机构：E China Univ Sci & Technol;Zhejiang Ocean Univ
- 来源：FISH & SHELLFISH IMMUNOLOGY 2010
- 关键词：Ferritin Immune-associated Large yellow croaker Attenuated live Vibrio anguillarum
- AdpAlin, a Pleiotropic Transcriptional Regulator, Is Involved in the Cascade Regulation of Lincomycin Biosynthesis in Streptomyces lincolnensis被引量：29收藏
- 作者：Kang, Yajing Wang, Yingying Hou, Bingbing Wang, Ruida Ye, Jiang Zhu, Xiaoyu Wu, Haizhen Zhang, Huizhan
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：FRONTIERS IN MICROBIOLOGY 2019
- 关键词：AdpA lincomycin Streptomyces lincolnensis transcriptional regulator cascade regulation
- Transgenic eukaryotic microalgae as green factories: providing new ideas for the production of biologically active substances被引量：27收藏
- 作者：Shi, Qianwen Chen, Cheng Zhang, Wei Wu, Ping Sun, Meng Wu, Hui Wu, Haizhen Fu, Pengcheng Fan, Jianhua
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Hainan Univ
- 来源：JOURNAL OF APPLIED PHYCOLOGY 2021
- 关键词：Eukaryotic microalgae Genetic engineering Metabolism Biopharmaceuticals production Therapeutic proteins
- Global regulator BldA regulates morphological differentiation and lincomycin production in Streptomyces lincolnensis被引量：26收藏
- 作者：Hou, Bingbing Tao, Liyuan Zhu, Xiaoyu Wu, Wei Guo, Meijin Ye, Jiang Wu, Haizhen Zhang, Huizhan
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 2018
- 关键词：S. lincolnensis bldA Leucine codon Morphological differentiation Lincomycin production Regulatory pathway
- Physiological and transcriptome analysis elucidates the metabolic mechanism of versatile Porphyridium purpureum under nitrogen deprivation for exopolysaccharides accumulation被引量：26收藏
- 作者：Ji, Liang Li, Shaohua Chen, Cheng Jin, Haojie Wu, Haizhen Fan, Jianhua
- 机构：East China Univ Sci & Technol;Beijing Forestry Univ;East China Univ Sci & Technol
- 来源：BIORESOURCES AND BIOPROCESSING 2021
- 关键词：Porphyridium purpureum Nitrogen deprivation Transcriptome analysis Exopolysaccharides Polyunsaturated fatty acids Phycoerythrin
- Molecular cloning and characterization of secretory and membrane-bound IgM of turbot被引量：25收藏
- 作者：Gao, Yuan Yi, Yangyang Wu, Haizhen Wang, Qiyao Qu, Jiangbo Zhang, Yuanxing
- 机构：E China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomgf Technol;Yantai Dev Zone TianYuan Aquat Prod Co Ltd
- 来源：FISH & SHELLFISH IMMUNOLOGY 2014
- 关键词：IgM Turbot Cloning Vibrio anguillarum Phagocytisis of B cell
