成果/Result
- Clodronate-loaded liposomal and fibroblast-derived exosomal hybrid system for enhanced drug delivery to pulmonary fibrosis被引量：157收藏
- 作者：Sun, Lingna Fan, Mingrui Huang, Dong Li, Bingqin Xu, Ruoting Gao, Feng Chen, Yanzuo
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：BIOMATERIALS 2021
- 关键词：Pulmonary fibrotic therapy Exosomes Liposomes Macrophages depletion Fibrosis penetration
- Nanodrug Delivery Systems Modulate Tumor Vessels to Increase the Enhanced Permeability and Retention Effect被引量：143收藏
- 作者：Huang, Dong Sun, Lingna Huang, Leaf Chen, Yanzuo
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Univ North Carolina
- 来源：JOURNAL OF PERSONALIZED MEDICINE 2021
- 关键词：nanoparticles tumor vascular regulation EPR effect angiogenesis blood perfusion vascular permeability
- Pluronic-based functional polymeric mixed micelles for co-delivery of doxorubicin and paclitaxel to multidrug resistant tumor被引量：116收藏
- 作者：Chen, Yanzuo Zhang, Wei Huang, Yukun Gao, Feng Sha, Xianyi Fang, Xiaoling
- 机构：E China Univ Sci & Technol;Fudan Univ;Fudan Univ;Eastern Virginia Med Sch
- 来源：INTERNATIONAL JOURNAL OF PHARMACEUTICS 2015
- 关键词：Doxorubicin Paclitaxel Codelivery Polymeric micelle Anti-cancer efficacy Multidrug resistance
- Combined Cancer Chemo-Photodynamic and Photothermal Therapy Based on ICG/PDA/TPZ-Loaded Nanoparticles被引量：108收藏
- 作者：Huang, Xiaqin Wu, Junru He, Muye Hou, Xinyu Wang, Yan Cai, Xiaoran Xin, Hongliang Gao, Feng Chen, Yanzuo
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;Nanjing Med Univ
- 来源：MOLECULAR PHARMACEUTICS 2019
- 关键词：nanoparticle chemo-photodynamic therapy photothermal therapy polydopamine indocyanine green tirapazamine Tumor
- Vasodilator Hydralazine Promotes Nanoparticle Penetration in Advanced Desmoplastic Tumors被引量：88收藏
- 作者：Chen, Yanzuo Song, Wantong Shen, Limei Qiu, Nasha Hu, Mengying Liu, Yun Liu, Qi Huang, Leaf
- 机构：Univ N Carolina;Univ N Carolina;East China Univ Sci & Technol;Chinese Acad Sci;Zhejiang Univ
- 来源：ACS NANO 2019
- 关键词：hydralazine nanoparticles tumor penetration desmoplastic tumor tumor microenvironment
- The preparation, characterization, and pharmacokinetic studies of chitosan nanoparticles loaded with paclitaxel/dimethyl-β-cyclodextrin inclusion complexes被引量：57收藏
- 作者：Ye, Ya-Jing Wang, Yun Lou, Kai-Yan Chen, Yan-Zuo Chen, Rongjun Gao, Feng
- 机构：E China Univ Sci & Technol;Univ London Imperial Coll Sci Technol & Med;E China Univ Sci & Technol;E China Univ Sci & Technol
- 来源：INTERNATIONAL JOURNAL OF NANOMEDICINE 2015
- 关键词：dimethyl-beta-cyclodextrin inclusion complex chitosan nanoparticles drug delivery sustained release paclitaxel
- Vitamin E Succinate-Grafted-Chitosan Oligosaccharide/RGD-Conjugated TPGS Mixed Micelles Loaded with Paclitaxel for U87MG Tumor Therapy被引量：45收藏
- 作者：Chen, Yanzuo Feng, Shu Liu, Wenchao Yuan, Zeting Yin, Peihao Gao, Feng
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Shanghai Univ Tradit Chinese Med
- 来源：MOLECULAR PHARMACEUTICS 2017
- 关键词：VES-grafted-CSO TPGS-RGD PTX mixed micelles U87MG tumor inhibition
- Preparation and characterization of mPEG grafted chitosan micelles as 5-fluorouracil carriers for effective anti-tumor activity被引量：44收藏
- 作者：Fu, Dong-Jun Jin, Yu Xie, Mu-Qing Ye, Ya-Jing Qin, Dong-Dong Lou, Kai-Yan Chen, Yan-Zuo Gao, Feng
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol;E China Univ Sci & Technol
- 来源：CHINESE CHEMICAL LETTERS 2014
- 关键词：Self-assembled micelles Methoxy polyethylene glycol grafted chitosan 5-Fluorouracil Controlled-release
- Cyclodextrin/chitosan nanoparticles for oral ovalbumin delivery: Preparation, characterization and intestinal mucosal immunity in mice被引量：43收藏
- 作者：He, Muye Zhong, Chen Hu, Huibing Jin, Yu Chen, Yanzuo Lou, Kaiyan Gao, Feng
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：ASIAN JOURNAL OF PHARMACEUTICAL SCIENCES 2019
- 关键词：beta-cyclodextrin Chitosan nanoparticles Ovalbumin Oral protein delivery Intestinal mucosal immunity
- Clodronate-nintedanib-loaded exosome-liposome hybridization enhances the liver fibrosis therapy by inhibiting Kupffer cell activity被引量：40收藏
- 作者：Ji, Keqin Fan, Mingrui Huang, Dong Sun, Lingna Li, Bingqin Xu, Ruoting Zhang, Jiajing Shao, Xuan Chen, Yanzuo
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：BIOMATERIALS SCIENCE 2022
- 关键词：Antigen-antibody reactions - Cell culture - Controlled drug delivery - Liver - Macrophages - Targeted drug delivery
- RETRACTED: c(RGDyK)-decorated Pluronic micelles for enhanced doxorubicin and paclitaxel delivery to brain glioma (Retracted Article)被引量：39收藏
- 作者：Huang, Yukun Liu, Wenchao Gao, Feng Fang, Xiaoling Chen, Yanzuo
- 机构：E China Univ Sci & Technol;Minist Educ;Fudan Univ
- 来源：INTERNATIONAL JOURNAL OF NANOMEDICINE 2016
- 关键词：Pluronic micelles integrin blood-brain barrier brain glioma targeted delivery
- Dual-functional c(RGDyK)-decorated Pluronic micelles designed for antiangiogenesis and the treatment of drug-resistant tumor被引量：29收藏
- 作者：Chen, Yanzuo Zhang, Wei Huang, Yukun Gao, Feng Fang, Xiaoling
- 机构：E China Univ Sci & Technol;Fudan Univ;Fudan Univ;Eastern Virginia Med Sch
- 来源：INTERNATIONAL JOURNAL OF NANOMEDICINE 2015
- 关键词：dual-functional micelles c(RGDyK) antiangiogenesis multidrug resistance
- Novel nanoparticles composed of chitosan and β-cyclodextrin derivatives as potential insoluble drug carrier被引量：29收藏
- 作者：Chen, Yan-Zuo Huang, Yu-Kun Chen, Yuan Ye, Ya-Jing Lou, Kai-Yan Gao, Feng
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol;E China Univ Sci & Technol;Shanghai Inst Hlth Sci
- 来源：CHINESE CHEMICAL LETTERS 2015
- 关键词：Chitosan Cyclodextrin derivatives Ionic gelation method Drug delivery system
- In Vivo Biodistribution and Anti-Tumor Efficacy Evaluation of Doxorubicin and Paclitaxel-Loaded Pluronic Micelles Decorated with c(RGDyK) Peptide被引量：25收藏
- 作者：Chen, Yanzuo Zhang, Wei Huang, Yukun Gao, Feng Fang, Xiaoling
- 机构：E China Univ Sci & Technol;Fudan Univ;Fudan Univ;Fudan Univ;Eastern Virginia Med Sch
- 来源：PLOS ONE 2016
- RETRACTED: The therapeutic effect of methotrexate-conjugated Pluronic-based polymeric micelles on the folate receptor-rich tumors treatment (Retracted Article)被引量：24收藏
- 作者：Chen, Yanzuo Zhang, Wei Huang, YuKun Gao, Feng Sha, Xianyi Lou, Kaiyan Fang, Xiaoling
- 机构：E China Univ Sci & Technol;Fudan Univ;Fudan Univ;Fudan Univ;Eastern Virginia Med Sch
- 来源：INTERNATIONAL JOURNAL OF NANOMEDICINE 2015
- 关键词：methotrexate-conjugated mixed micelles folate receptor Pluronic KBv cells
- Biological Hyperthermia-Inducing Nanoparticles for Specific Remodeling of the Extracellular Matrix Microenvironment Enhance Pro-Apoptotic Therapy in Fibrosis被引量：24收藏
- 作者：Zhang, Jinru Ji, Keqin Ning, Yuanmeng Sun, Lingna Fan, Mingrui Shu, Chunjie Zhang, Ziqi Tu, Tianyu Cao, Jingyun Gao, Feng Chen, Yanzuo
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：ACS NANO 2023
- 关键词：fibrosis exosome and liposome hybrid nanoparticles hyperthermia 2 4-dinitrophenol remodelingof the extracellular matrix microenvironment
- β-Cyclodextrin-Based Inclusion Complexation Bridged Biodegradable Self-Assembly Macromolecular Micelle for the Delivery of Paclitaxel被引量：23收藏
- 作者：Chen, Yanzuo Huang, Yukun Qin, Dongdong Liu, Wenchao Song, Chao Lou, Kaiyan Wang, Wei Gao, Feng
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol;E China Univ Sci & Technol;E China Univ Sci & Technol;E China Univ Sci & Technol
- 来源：PLOS ONE 2016
- Targeting integrin-rich tumors with temoporfin-loaded vitamin-E-succinate-grafted chitosan oligosaccharide/D-α-tocopheryl polyethylene glycol 1000 succinate nanoparticles to enhance photodynamic therapy efficiency被引量：20收藏
- 作者：Wu, Junru Feng, Shu Liu, Wenchao Gao, Feng Chen, Yanzuo
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：INTERNATIONAL JOURNAL OF PHARMACEUTICS 2017
- 关键词：Temoporfin Photodynamic therapy Nanoparticles Tumor targeting
- Tofacitinib Citrate Coordination-Based Dual-Responsive/Scavenge Nanoplatform Toward Regulate Colonic Inflammatory Microenvironment for Relieving Colitis被引量：16收藏
- 作者：Zou, Jiafeng Jiang, Kun Chen, You Ma, Ying Xia, Chuanhe Ding, Wenxing Yao, Min Lin, Yiting Chen, Yanzuo Zhao, Yuzheng Gao, Feng
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Chinese Acad Med Sci;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：ADVANCED HEALTHCARE MATERIALS 2024
- 关键词：colitis colonic inflammatory microenvironment coordination nanoplatform dual-responsive dual-scavenge tofacitinib citrate
- Vitamin E succinate-grafted-chitosan/chitosan oligosaccharide mixed micelles loaded with C-DMSA for Hg2+ detection and detoxification in rat liver被引量：7收藏
- 作者：Wei, Binghui He, Muye Cai, Xiaoran Hou, Xinyu Wang, Yujie Chen, Jiaojiao Lan, Minbo Chen, Yanzuo Lou, Kaiyan Gao, Feng
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：INTERNATIONAL JOURNAL OF NANOMEDICINE 2019
- 关键词：micelles C-DMSA mercury poisoning detection and detoxification drug delivery system
- An anti-miR-301a and zinc coordination driven nanozyme loaded in nanoparticle for oral therapy of inflammatory bowel disease based on colitis microenvironment regulation被引量：6收藏
- 作者：Zou, Jiafeng Xia, Chuanhe Yao, Min Pan, Xier Zheng, Shulei Lin, Yiting Zhao, Xinlin Wang, Yanwen Chen, Yanzuo Lan, Minbo Wang, Junshan Gao, Feng
- 机构：East China Univ Sci & Technol;Tongji Univ;Bengbu First Peoples Hosp;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：CHEMICAL ENGINEERING JOURNAL 2025
- 关键词：Coordination driven nanozyme Anti-miR-301a Zinc Colitis microenvironment regulation Inflammatory bowel disease Oral nanoparticle
- Rapamycin and Hyperoside-Co-loaded Macrophage Delivery System Enhanced Pulmonary Fibrosis Therapy by Autophagy Upregulation and Epithelial-to-Mesenchymal Transition Inhibition被引量：4收藏
- 作者：Wang, Qi Ning, Yuanmeng Zhang, Jinru Du, Xu Xu, Zihan Hu, Yongcheng Gao, Feng Chen, Yanzuo
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：ACS APPLIED MATERIALS & INTERFACES 2024
- 关键词：pulmonary fibrosis autophagy epithelial-to-mesenchymaltransition macrophage drug delivery system extracellulartraps
- Dual-functional C(RGDYK)-decorated pluronic micelles for antiangiogenesis and drug resistant tumor treatment in vitro被引量：2收藏
- 作者：Chen, Yanzuo Gao, Feng Sha, Xianyi Fang, Xiaoling
- 机构：E China Univ Sci & Technol;Fudan Univ;Fudan Univ
- 来源：NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE 2016
- Exosome-liposome hybrid system with antioxidant and anti-inflammatory activities targeting glial cells for the treatment of central nervous system diseases被引量：1收藏
- 作者：Chen, Yutong Guo, Shuting Fan, Mingrui Yang, Songlin Lin, Qiuxia Zou, Jiafeng Xu, Junyuan Zheng, Tongtong He, Kangtai Gao, Feng Chen, Yanzuo
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：CHINESE CHEMICAL LETTERS 2026
- 关键词：Central nervous system disease Glial cells Exosome-liposome hybrid system Fisetin Pioglitazone
- Clodronate-nintedanib-loaded exosome-liposome hybridization enhances the liver fibrosis therapy by inhibiting Kupffer cell activity (vol 10, pg 702, 2022)被引量：0收藏
- 作者：Ji, Keqin Fan, Mingrui Huang, Dong Sun, Lingna Li, Bingqin Xu, Ruoting Zhang, Jiajing Shao, Xuan Chen, Yanzuo
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：BIOMATERIALS SCIENCE 2024
- Methotrexate-conjugated polymeric micelles in the folate receptor-rich cancer treatment and safety evaluation被引量：0收藏
- 作者：Huang, Yukun Gao, Feng Fang, Xiaoling Chen, Yanzuo
- 机构：E China Univ Sci & Technol;Fudan Univ;Fudan Univ
- 来源：NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE 2016
- Study on self-assembly micelle drug delivery systems based on host-guest interactions被引量：0收藏
- 作者：Qin, Dongdong Chen, Yanzuo Gao, Feng
- 机构：E China Univ Sci & Technol
- 来源：NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE 2016
