成果/Result
- Smart plant-wearable biosensor for in-situ pesticide analysis被引量：195收藏
- 作者：Zhao, Fengnian He, Jianwei Li, Xunjia Bai, Yunpeng Ying, Yibin Ping, Jianfeng
- 机构：Zhejiang Univ;East China Univ Sci & Technol;Zhejiang A&F Univ
- 来源：BIOSENSORS & BIOELECTRONICS 2020
- 关键词：Wearable biosensor Graphene In-situ analysis Pesticide residue Precision agriculture
- Preparation of Structurally Diverse Chiral Alcohols by Engineering Ketoreductase CgKR1被引量：82收藏
- 作者：Zheng, Gao-Wei Liu, Yuan-Yang Chen, Qi Huang, Lei Yu, Hui-Lei Lou, Wen-Yong Li, Chun-Xiu Bai, Yun-Peng Li, Ai-Tao Xu, Jian-He
- 机构：East China Univ Sci & Technol;South China Univ Technol;Max Planck Inst Kohlenforsch
- 来源：ACS CATALYSIS 2017
- 关键词：asymmetric reduction ketoreductase chiral alcohol protein engineering substrate specificity biocatalysis
- Biodegradation of Structurally Diverse Phthalate Esters by a Newly Identified Esterase with Catalytic Activity toward Di(2-ethylhexyl) Phthalate被引量：75收藏
- 作者：Huang, Han Zhang, Xiao-Yan Chen, Tian-Lei Zhao, Yu-Lian Xu, Dian-Sheng Bai, Yun-Peng
- 机构：East China Univ Sci & Technol
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2019
- 关键词：Gordonia polyisoprenivorans esterase bis(2-ethylhexyl) phthalate phthalate esters biodegradation
- Bioremediation of phenolic pollutants by algae-current status and challenges被引量：60收藏
- 作者：Wu, Ping Zhang, Zhaofei Luo, Yeling Bai, Yunpeng Fan, Jianhua
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：BIORESOURCE TECHNOLOGY 2022
- 关键词：Algae Phenolic pollutants Removal mechanisms Industrial value
- Coimmobilized Dual Enzymes in a Continuous Flow Reactor for the Efficient Synthesis of Optically Pure γ/δ-Lactones被引量：56收藏
- 作者：Yuan, Pengyu Wang, Qing Deng, Xuelei Zhang, Xiaoyan Fan, Daidi Bai, Yunpeng
- 机构： State Key Laboratory of Bioreactor Engineering; Shaanxi R&D Centre of Biomaterials and Fermentation Engineering
- 来源：ACS Applied Materials and Interfaces 2025
- 关键词：Doping (additives) - Green Synthesis - Reaction rates - Stereoselectivity
- Improved synthesis of 2,5-bis(hydroxymethyl)furan from 5-hydroxymethylfurfural using acclimatized whole cells entrapped in calcium alginate被引量：54收藏
- 作者：Xu, Zhong-Hua Cheng, Ai-Di Xing, Xu-Pu Zong, Min-Hua Bai, Yun-Peng Li, Ning
- 机构：South China Univ Technol;East China Univ Sci & Technol
- 来源：BIORESOURCE TECHNOLOGY 2018
- 关键词：Biocatalysis Biobased platform chemicals Immobilization Reduction Whole cells
- Confining Enzyme Clusters in Bacteriophage P22 Enhances Cofactor Recycling and Stereoselectivity for Chiral Alcohol Synthesis被引量：40收藏
- 作者：Zhang, Yan-Qing Feng, Tao-Tao Cao, Yu-Fei Zhang, Xiao-Yan Wang, Tao Nina, Mario Roque Huanca Wang, Li-Cheng Yu, Hui-Lei Xu, Jian-He Ge, Jun Bai, Yun-Peng
- 机构：East China Univ Sci & Technol ECUST;Tsinghua Univ;Tsinghua Shenzhen Int Grad Sch;Shenzhen Bay Lab;Tsinghua Univ
- 来源：ACS CATALYSIS 2021
- 关键词：enzyme cluster enzymatic catalysis cofactor recycling confinement effects asymmetric reduction
- A novel D-mandelate dehydrogenase used in three-enzyme cascade reaction for highly efficient synthesis of non-natural chiral amino acids被引量：40收藏
- 作者：Fan, Chang-Wei Xu, Guo-Chao Ma, Bao-Di Bai, Yun-Peng Zhang, Jie Xu, Jian-He
- 机构：E China Univ Sci & Technol
- 来源：JOURNAL OF BIOTECHNOLOGY 2015
- 关键词：D-Mandelate dehydrogenase L-Phenylglycine Asymmetric synthesis Cascade reaction Process optimization
- Transcription Factor Engineering for High-Throughput Strain Evolution and Organic Acid Bioproduction: A Review被引量：37收藏
- 作者：Li, Jia-Wei Zhang, Xiao-Yan Wu, Hui Bai, Yun-Peng
- 机构：East China Univ Sci & Technol
- 来源：FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY 2020
- 关键词：transcription factor biosensor metabolic engineering synthetic biology organic acid high-throughput screening
- Microfluidic reactor with immobilized enzyme-from construction to applications: A review被引量：31收藏
- 作者：Zhang, Han Bai, Yunpeng Zhu, Ning Xu, Jianhe
- 机构：East China Univ Sci & Technol;Nanjing Tech Univ
- 来源：CHINESE JOURNAL OF CHEMICAL ENGINEERING 2021
- 关键词：Microfluidic immobilized enzyme reactor Immobilization strategies Biocatalysis Bioconversion Bioanalysis
- Flocculation of Chlamydomonas reinhardtii with Different Phenotypic Traits by Metal Cations and High pH被引量：31收藏
- 作者：Fan, Jianhua Zheng, Lvhong Bai, Yunpeng Saroussi, Shai Grossman, Arthur R.
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Carnegie Inst Sci
- 来源：FRONTIERS IN PLANT SCIENCE 2017
- 关键词：flocculation cell wall deficient Chlamydomonas multivalent metal ions microalgae pH algal biotechnology
- Efficient Stereoselective Synthesis of Structurally Diverse γ- and δ-Lactones Using an Engineered Carbonyl Reductase被引量：26收藏
- 作者：Chen, Meng Zhang, Xiao-Yan Xing, Chen-Guang Zhang, Chao Zheng, Yu-Cong Pan, Jiang Xu, Jian-He Bai, Yun-Peng
- 机构：East China Univ Sci & Technol;Xiamen Oamic Biotech Co Ltd
- 来源：CHEMCATCHEM 2019
- 关键词：Asymmetric reduction directed evolution chiral lactones carbonyl reductase biocatalysis
- Combinatorial Evolution of Phosphotriesterase Toward a Robust Malathion Degrader by Hierarchical Iteration Mutagenesis被引量：25收藏
- 作者：Luo, Xiao-Jing Zhao, Jian Li, Chun-Xiu Bai, Yun-Peng Reetz, Manfred T. Yu, Hui-Lei Xu, Jian-He
- 机构：East China Univ Sci & Technol;Max Planck Inst Kohlenforsch;Philipps Univ Marburg
- 来源：BIOTECHNOLOGY AND BIOENGINEERING 2016
- 关键词：biocatalysis directed evolution DNA shuffling malathion phosphotriesterase
- An engineered quorum-sensing-based whole-cell biosensor for active degradation of organophosphates被引量：25收藏
- 作者：He, Jianwei Zhang, Xiaoyan Qian, Yuanyi Wang, Qiyao Bai, Yunpeng
- 机构：East China Univ Sci & Technol
- 来源：BIOSENSORS & BIOELECTRONICS 2022
- 关键词：Whole-cell biosensor Synthetic biology Genetic circuits Quorum sensing Degradation
- Engineering Transcription Factor XylS for Sensing Phthalic Acid and Terephthalic Acid: An Application for Enzyme Evolution被引量：23收藏
- 作者：Li, Jiawei Nina, Mario Roque Huanca Zhang, Xiaoyan Bai, Yunpeng
- 机构：East China Univ Sci & Technol
- 来源：ACS SYNTHETIC BIOLOGY 2022
- 关键词：biosensor transcription factor engineering phthalic acid terephthalic acid enzyme evolution biodegradation
- 面向生物医药新工科方向的生物工程一流本科专业建设探索与实践被引量：23收藏
- 作者：王启要 高淑红 白云鹏 任国宾 庄英萍 宋恭华
- 机构：华东理工大学生物工程学院;华东理工大学药学院
- 来源：《生物工程学报》 2022
- 关键词：生物医药新工科 三位一体 三全育人 课程体系
- 摘要：《“健康中国2030”规划纲要》将生物医药列为重点规划发展领域,上海也将生物医药列为重要新兴支柱产业。生物医药产业的快速发展对人才需求提出了更高要求。华东理工大学生物工程学院秉承交叉融合、互惠发展、传承创新的思路,将生物...
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- Continuous-Flow Microreactor-Enhanced Clean NAD+ Regeneration for Biosynthesis of 7-Oxo-lithocholic Acid被引量：22收藏
- 作者：Li, Hai-Peng You, Zhi-Neng Liu, Yuan-Yang Zheng, Gao-Wei Gong, Heng Mo, Yiming Zhu, Ning Bai, Yun-Peng Xu, Jian-He
- 机构：East China Univ Sci & Technol;Zhejiang Univ;Nanjing Tech Univ
- 来源：ACS SUSTAINABLE CHEMISTRY & ENGINEERING 2022
- 关键词：Cofactor regeneration Continuous-flow microreactor NAD(P)H oxidases Oxygen transfer Space-time yield Enzyme consumption number Total turnover number
- Asymmetric bioreduction of keto groups of 4-and 5-Oxodecanoic acids/esters with a new carbonyl reductase被引量：19收藏
- 作者：Zhang, Chao Pan, Jiang Li, Chun-Xiu Bai, Yun-Peng Xu, Jian-He
- 机构：East China Univ Sci & Technol
- 来源：CATALYSIS COMMUNICATIONS 2017
- 关键词：4-Oxodecanoic acid 5-Oxodecanoic acid (R)-gamma-Decalactone (R)-delta-Decalactone Carbonyl reductase Asymmetric reduction
- Enhancing transglutaminase production of Streptomyces mobaraensis by iterative mutagenesis breeding with atmospheric and room-temperature plasma (ARTP)被引量：19收藏
- 作者：Jiang, Ying Shang, Yue-Peng Li, Hao Zhang, Chao Pan, Jiang Bai, Yun-Peng Li, Chun-Xiu Xu, Jian-He
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：BIORESOURCES AND BIOPROCESSING 2017
- 关键词：Atmospheric and room-temperature plasma Breeding Streptomyces mobaraensis Transcription level Transglutaminase
- Continuous-flow enzymatic synthesis of chiral lactones in a three-dimensional microfluidic reactor被引量：18收藏
- 作者：Deng, Xuelei Fan, Meng Wu, Miao Zhang, Xiaoyan Cheng, Ya Xia, Jianye Zhuang, Yingping Zhu, Weiping Qian, Xuhong Bai, Yunpeng
- 机构：East China Univ Sci & Technol;East China Normal Univ;Chinese Acad Sci
- 来源：CHINESE CHEMICAL LETTERS 2024
- 关键词：Continuous-flow Flow chemistry Microreactor Biocatalysis Carbonyl reductase Asymmetric reduction
- Efficient Degradation of Malathion in the Presence of Detergents Using an Engineered Organophosphorus Hydrolase Highly. Expressed by Pichia pastoris without Methanol Induction被引量：17收藏
- 作者：Bai, Yun-Peng Luo, Xiao-Jing Zhao, Yu-Lian Li, Chun-Xiu Xu, Dian-Sheng Xu, Jian-He
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2017
- 关键词：biodegradation Pichia pastoris organophosphorus hydrolase extracellular expression malathion
- Cross-linked enzyme-polymer conjugates with excellent stability and detergent-enhanced activity for efficient organophosphate degradation被引量：17收藏
- 作者：Cheng, Huan Zhao, Yu-Lian Luo, Xiao-Jing Xu, Dian-Sheng Cao, Xun Xu, Jian-He Dai, Qing Zhang, Xiao-Yan Ge, Jun Bai, Yun-Peng
- 机构：East China Univ Sci & Technol;Tsinghua Univ;Natl Ctr Nanosci & Technol
- 来源：BIORESOURCES AND BIOPROCESSING 2018
- 关键词：Organophosphate Organophosphate hydrolase Immobilization Biodegradation Enzyme-polymer conjugates Pluronic F127
- A novel dihydroxylated derivative of artemisinin from microbial transformation被引量：17收藏
- 作者：Zhan, Yulian Wu, Yunshan Xu, Fangfang Bai, Yunpeng Guan, Yezhi Williamson, John S. Liu, Bo
- 机构：Guilin Univ Elect Technol;East China Univ Sci & Technol;Guangzhou Univ Chinese Med;Univ Mississippi;Guangzhou Univ Chinese Med
- 来源：FITOTERAPIA 2017
- 关键词：Microbial transformation Artemisinin Cunninghamella elegans Antimalarial drugs
- Continuous-flow synthesis of polysubstituted γ -butyrolactones via enzymatic cascade catalysis被引量：16收藏
- 作者：Chu, Liliang Zhang, Xiaoyan Li, Jianing Deng, Xuelei Wu, Miao Cheng, Ya Zhu, Weiping Qian, Xuhong Bai, Yunpeng
- 机构：East China Univ Sci & Technol;East China Normal Univ
- 来源：CHINESE CHEMICAL LETTERS 2024
- 关键词：Enzyme catalysis Cascade catalysis Directed evolution Continuous-flow gamma -Butyrolactones
- Stereoselective synthesis of chiral δ-lactones via an engineered carbonyl reductase被引量：14收藏
- 作者：Wang, Tao Zhang, Xiao-Yan Zheng, Yu-Cong Bai, Yun-Peng
- 机构：East China Univ Sci & Technol
- 来源：CHEMICAL COMMUNICATIONS 2021
- 关键词：Stereoselectivity - Cost effectiveness - Substrates - Esters
- 探微知著,辟新为用——华东理工大学生物工程新工科专业建设实践被引量：14收藏
- 作者：白云鹏 王启要 庄英萍 范惠明
- 机构：华东理工大学生物工程学院;华东理工大学高等教育研究所
- 来源：《高等工程教育研究》 2021
- 关键词：新工科 生物工程 智能生物制造 知识结构 工程能力
- 摘要：针对蓬勃发展的生物新经济对高素质人才的需求,华东理工大学生物工程专业在总结梳理传统生物工程专业办学经验的基础上,开展了"智能生物制造"新工科专业建设的探索和实践,以理工课程深度融合、学生创新与应用能力协调培养的专业建设思...
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- Direct Access to Medium-Chain α,ω-Dicarboxylic Acids by Using a Baeyer-Villiger Monooxygenase of Abnormal Regioselectivity被引量：14收藏
- 作者：Yu, Jia-Mei Liu, Yuan-Yang Zheng, Yu-Cong Li, Hao Zhang, Xiao-Yan Zheng, Gao-Wei Li, Chun-Xiu Bai, Yun-Peng Xu, Jian-He
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：CHEMBIOCHEM 2018
- 关键词：biocatalysis dicarboxylic acids oxidation regioselectivity renewable resources
- Micro/nano flow chemistry by Beyond Limits Manufacturing被引量：13收藏
- 作者：Liu, Peiwen Zhao, Fang Zhang, Jing Bai, Yunpeng Ye, Jinxing Bao, Bo Zhou, Xinggui Zhang, Li Zhou, Changlu Yu, Xinhai Zuo, Peng Xia, Jianye Cen, Lian Yang, Yangyang Shi, Guoyue Xu, Lin Zhu, Weiping Xu, Yufang Qian, Xuhong
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;Guangdong Univ Technol;East China Univ Sci & Technol
- 来源：CHINESE CHEMICAL LETTERS 2024
- 关键词：Beyond Limits Manufacturing Flow chemistry Pharmaceutical manufacturing Microreactor
- Enzyme-photo-coupled catalysis in gas-sprayed microdroplets被引量：13收藏
- 作者：Bai, Yunxiu Luan, Pengqian Bai, Yunpeng Zare, Richard N. Ge, Jun
- 机构：Tsinghua Univ;Shenzhen Bay Lab;East China Univ Sci & Technol ECUST;Stanford Univ;Tsinghua Shenzhen Int Grad Sch
- 来源：CHEMICAL SCIENCE 2022
- 关键词：Energy utilization - Enzyme activity - Large scale systems - Solar energy
- Paper-Based Enzymatic Colorimetric Assay for Rapid Malathion Detection被引量：13收藏
- 作者：Li, Jian-Hui Deng, Xue-Lei Zhao, Yu-Lian Zhang, Xiao-Yan Bai, Yun-Peng
- 机构：Ocean Univ China;East China Univ Sci & Technol
- 来源：APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY 2021
- 关键词：Enzyme immobilization Paper-based biosensor Malathion detection Polymer– enzyme conjugate Organophosphate hydrolase
