成果/Result
- Influence of High Solid Concentration on Enzymatic Hydrolysis and Fermentation of Steam-Exploded Corn Stover Biomass被引量：148收藏
- 作者：Lu, Yifeng Wang, Yonghong Xu, Guoqian Chu, Ju Zhuang, Yingping Zhang, Siliang
- 机构：E China Univ Sci & Technol
- 来源：APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY 2010
- 关键词：Bioethanol Corn stover High solid concentration Enzymatic hydrolysis Fermentation
- GAP Promoter Library for Fine-Tuning of Gene Expression in Pichia pastoris被引量：113收藏
- 作者：Qin, Xiulin Qian, Jiangchao Yao, Gaofeng Zhuang, Yingping Zhang, Siliang Chu, Ju
- 机构：E China Univ Sci & Technol
- 来源：APPLIED AND ENVIRONMENTAL MICROBIOLOGY 2011
- Optimization of cellulase mixture for efficient hydrolysis of steam-exploded corn stover by statistically designed experiments被引量：112收藏
- 作者：Zhou, Jin Wang, Yong-Hong Chu, Ju Luo, Ling-Zhi Zhuang, Ying-Ping Zhang, Si-Liang
- 机构：E China Univ Sci & Technol
- 来源：BIORESOURCE TECHNOLOGY 2009
- 关键词：Cellulase mixture Optimization Steam-exploded corn stover Statistically designed experiments Bioethanol
- Salt stress induced lipid accumulation in heterotrophic culture cells of Chlorella protothecoides: Mechanisms based on the multi-level analysis of oxidative response, key enzyme activity and biochemical alteration被引量：100收藏
- 作者：Wang, Tao Ge, Haiyan Liu, Tingting Tian, Xiwei Wang, Zejian Guo, Meijin Chu, Ju Zhuang, Yingping
- 机构：E China Univ Sci & Technol
- 来源：JOURNAL OF BIOTECHNOLOGY 2016
- 关键词：Chlorella protothecoides Heterotrophic culture Lipid Microalgae ROS Salt stress
- Efficient generation of multi-copy strains for optimizing secretory expression of porcine insulin precursor in yeast Pichia pastoris被引量：97收藏
- 作者：Zhu, T. Guo, M. Tang, Z. Zhang, M. Zhuang, Y. Chu, J. Zhang, S.
- 机构：E China Univ Sci & Technol;Jiangxi Agr Univ
- 来源：JOURNAL OF APPLIED MICROBIOLOGY 2009
- 关键词：gene dosage multi-copy Pichia pastoris physiological performance porcine insulin precursor
- Identification and purification of the main components of cellulases from a mutant strain of Trichoderma viride T 100-14被引量：94收藏
- 作者：Zhou, Jin Wang, Yong-Hong Chu, Ju Zhuang, Ying-Ping Zhang, Si-Liang Yin, Peng
- 机构：E China Univ Sci & Technol
- 来源：BIORESOURCE TECHNOLOGY 2008
- 关键词：Trichoderma viride T 100-14 mutant strain cellulase identification purification
- Microbial production of 2,3-butanediol by a surfactant (serrawettin)-deficient mutant of Serratia marcescens H30被引量：87收藏
- 作者：Zhang, Liaoyuan Sun, Jian'an Hao, Yingli Zhu, Jiawen Chu, Ju Wei, Dongzhi Shen, Yaling
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol
- 来源：JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY 2010
- 关键词：2,3-Butanediol Serrawettin W1 synthase Inactivation Serratia marcescens Fed-batch
- Developing a Computational Framework To Advance Bioprocess Scale-Up被引量：87收藏
- 作者：Wang, Guan Haringa, Cees Noorman, Henk Chu, Ju Zhuang, Yingping
- 机构：East China Univ Sci & Technol ECUST;DSM Biotechnol Ctr;Delft Univ Technol
- 来源：TRENDS IN BIOTECHNOLOGY 2020
- 关键词：Metabolism
- Integration of microbial kinetics and fluid dynamics toward model-driven scale-up of industrial bioprocesses被引量：81收藏
- 作者：Wang, Guan Tang, Wenjun Xia, Jianye Chu, Ju Noorman, Henk van Gulik, Walter M.
- 机构： State Key Laboratory of Bioreactor Engineering; DSM Biotechnology Center; Department of Biotechnology
- 来源：Engineering in Life Sciences 2020
- 关键词：Metabolism - Mass transfer - Mixing - Metabolic engineering - Batch data processing - Kinetics - Carbon dioxide
- Improved vitamin B12 production by step-wise reduction of oxygen uptake rate under dissolved oxygen limiting level during fermentation process被引量：74收藏
- 作者：Wang, Ze-Jian Wang, Hui-Yuan Li, Yong-Liang Chu, Ju Huang, Ming-Zhi Zhuang, Ying-Ping Zhang, Si-Liang
- 机构：E China Univ Sci & Technol;Grp Hua Rong Pharmaceut Co Ltd
- 来源：BIORESOURCE TECHNOLOGY 2010
- 关键词：Vitamin B-12 Oxygen uptake rate Pseudomonas denitrificans Scale-up Oxygen supply strategy
- Integration of microbial kinetics and fluid dynamics toward model-driven scale-up of industrial bioprocesses被引量：74收藏
- 作者：Wang, Guan Tang, Wenjun Xia, Jianye Chu, Ju Noorman, Henk van Gulik, Walter M.
- 机构：E China Univ Sci & Technol;DSM Biotechnol Ctr;Delft Univ Technol
- 来源：ENGINEERING IN LIFE SCIENCES 2015
- 关键词：Computational fluid dynamics Heterogeneity Mathematical model Scale down Scale up
- Development of a continuous cell-recycle fermentation system for production of lactic acid by Lactobacillus paracasei被引量：65收藏
- 作者：Xu, Guo-qian Chu, Ju Wang, Yong-hong Zhuang, Ying-ping Zhang, Si-liang Peng, Hua-qiong
- 机构：E China Univ Sci & Technol
- 来源：PROCESS BIOCHEMISTRY 2006
- 关键词：electromagnetic flow-meter Lactobacillus paracasei lactic acid tangential velocity membrane bioreactor cell-recycle
- Metabolic engineering coupled with adaptive evolution strategies for the efficient production of high-quality L-lactic acid by Lactobacillus paracasei被引量：65收藏
- 作者：Tian, Xiwei Liu, Xuehua Zhang, Yifan Chen, Yang Hang, Haifeng Chu, Ju Zhuang, Yingping
- 机构：East China Univ Sci & Technol
- 来源：BIORESOURCE TECHNOLOGY 2021
- 关键词：Lactobacillus paracasei Lactic acid CRISPR Cas9 Adaptive evolution Open fermentation
- Oxygen uptake rate optimization with nitrogen regulation for erythromycin production and scale-up from 50 L to 372 m3 scale被引量：64收藏
- 作者：Zou, Xiang Hang, Hai-feng Chu, Ju Zhuang, Ying-ping Zhang, Si-liang
- 机构：E China Univ Sci & Technol;Southwest Univ
- 来源：BIORESOURCE TECHNOLOGY 2009
- 关键词：Erythromycin Industrial scale Metabolic flux Oxygen uptake rate Scale-up
- Enhancement of phototrophic hydrogen production by Rhodobacter sphaeroides ZX-5 using a novel strategy - shaking and extra-light supplementation approach被引量：62收藏
- 作者：Li, Xu Wang, Yong-Hong Zhang, Si-Liang Chu, Ju Zhang, Ming Huang, Ming-Zhi Zhuang, Ying-Ping
- 机构：E China Univ Sci & Technol
- 来源：INTERNATIONAL JOURNAL OF HYDROGEN ENERGY 2009
- 关键词：Photo-hydrogen production Rhodobacter sphaeroides Light intensity Hydrogen production rate Light attenuation kinetics
- Fluid dynamics investigation of variant impeller combinations by simulation and fermentation experiment被引量：61收藏
- 作者：Xia, Jian-Ye Wang, Yong-Hong Zhang, Si-Liang Chen, Ning Yin, Peng Zhuang, Ying-Ping Chu, Ju
- 机构：E China Univ Chem Technol
- 来源：BIOCHEMICAL ENGINEERING JOURNAL 2009
- 关键词：Dissolved oxygen Fluid mechanics Gas-liquid mass transfer Mixing Mycelia fermentation Shear environment
- Genetic modulation of the overexpression of tailoring genes eryK and eryG leading to the improvement of erythromycin a purity and production in Saccharopolyspora erythraea fermentation被引量：60收藏
- 作者：Chen, Yun Deng, Wei Wu, Jiequn Qian, Jiangchao Chu, Ju Zhuang, Yingping Zhang, Siliang Liu, Wen
- 机构：E China Univ Sci & Technol;Chinese Acad Sci
- 来源：APPLIED AND ENVIRONMENTAL MICROBIOLOGY 2008
- Flow Pattern, Mixing, Gas Hold-Up and Mass Transfer Coefficient of Triple-Impeller Configurations in Stirred Tank Bioreactors被引量：60收藏
- 作者：Xie, Minghui Xia, Jianye Zhou, Zhen Chu, Ju Zhuang, Yingping Zhang, Siliang
- 机构：E China Univ Sci & Technol
- 来源：INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH 2014
- 关键词：Gases - Liquids - Mixing - Pumps - Turbine components - Flow patterns - Mass transfer - Turbomachine blades - Velocity
- Screening endogenous signal peptides and protein folding factors to promote the secretory expression of heterologous proteins in Pichia pastoris被引量：59收藏
- 作者：Duan, Guangdong Ding, Lumei Wei, Dongsheng Zhou, Hangcheng Chu, Ju Zhang, Siliang Qian, Jiangchao
- 机构：East China Univ Sci & Technol
- 来源：JOURNAL OF BIOTECHNOLOGY 2019
- 关键词：Signal peptides Folding factors Pichia pastoris Heterologous protein Secretory expression
- Progress in the research of S-adenosyl-L-methionine production被引量：59收藏
- 作者：Chu, Ju Qian, Jiangchao Zhuang, Yingping Zhang, Siliang Li, Yourong
- 机构：E China Univ Sci & Technol
- 来源：APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 2013
- 关键词：S-adenosyl-L-methionine L-Methionine ATP L-Methionine adenosyltransferase Pichia pastoris
- Industrial bioprocess control and optimization in the context of systems biotechnology被引量：56收藏
- 作者：Wang, Yong Chu, Ju Zhuang, Yingping Wang, Yonghong Xia, Jianye Zhang, Siliang
- 机构： State Key Laboratory of Bioreactor Engineering
- 来源：Biotechnology Advances 2009
- Pillar[5]arene-Based Acid-Triggered Supramolecular Porphyrin Photosensitizer for Combating Bacterial Infections and Biofilm Dispersion被引量：55收藏
- 作者：Xia, Lei Tian, Jia Yue, Tao Cao, Hongliang Chu, Ju Cai, Haibo Zhang, Weian
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：ADVANCED HEALTHCARE MATERIALS 2022
- 关键词：antibacterial photodynamic arene porphyrin supramolecular
- Enhancement of phototrophic hydrogen production by Rhodobacter sphaeroides ZX-5 using a novel strategy - shaking and extra-light supplementation approach被引量：52收藏
- 作者：Li, Xu Wang, Yong-Hong Zhang, Si-Liang Chu, Ju Zhang, Ming Huang, Ming-Zhi Zhuang, Ying-Ping
- 机构： State Key Laboratory of Bioreactor Engineering
- 来源：International Journal of Hydrogen Energy 2009
- 关键词：Image enhancement - Production efficiency
- 重组巴氏毕赤酵母高密度发酵表达rHSA被引量：49收藏
- 作者：郭美锦 庄英萍 储炬 张嗣良 刘志敏
- 机构：华东理工大学生物反应器工程国家重点实验室;军事医学科学院生物工程研究所
- 来源：《微生物学报》 2002
- 关键词：重组巴斯德毕赤酵母 高密度发酵 重组人血清白蛋白 rHSA 表达
- 摘要：对基因工程菌Pichiapastoris的摇瓶发酵条件进行了试验 ,并根据摇瓶发酵的优化结果进行了补料分批高密度发酵。在摇瓶发酵时 ,甲醇诱导基因工程菌P .pastoris表达重组人血清白蛋白的发酵周期为 96h ;甲...
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- Application of Euler-Lagrange CFD for quantitative evaluating the effect of shear force on Carthamus tinctorius L. cell in a stirred tank bioreactor被引量：49收藏
- 作者：Liu, Yu Wang, Ze-Jian Xia, Jian-Ye Haringa, Cees Liu, Ya-Ping Chu, Ju Zhuang, Ying-Ping Zhang, Si-Liang
- 机构：East China Univ Sci & Technol;Dalian Pract Biotechnol Co Ltd;Delft Univ Technol
- 来源：BIOCHEMICAL ENGINEERING JOURNAL 2016
- 关键词：Plant cell culture Fluid mechanics Agitation Power consumption C tinctorius L. cell Stress thresholds
- CFD analysis of the turbulent flow in baffled shake flasks被引量：49收藏
- 作者：Li, Chao Xia, Jian-Ye Chu, Ju Wang, Yong-Hong Zhuang, Ying-Ping Zhang, Si-Liang
- 机构：E China Univ Sci & Technol
- 来源：BIOCHEMICAL ENGINEERING JOURNAL 2013
- 关键词：Shake flask Hydrodynamics Mass transfer Mixing Shear force Power consumption
- Sustainable biosynthesis of curdlan from orange waste by using Alcaligenes faecalis: A systematically modeled approach被引量：48收藏
- 作者：Mohsin, Ali Sun, Jingyun Khan, Imran Mahmood Hang, Haifeng Tariq, Muhammad Tian, Xiwei Ahmed, Waqas Niazi, Sobia Zhuang, Yingping Chu, Ju Mohsin, Muhammad Zubair Salim-ur-Rehman Guo, Meijin
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Jiangnan Univ;Univ Agr Faisalabad;Univ Agr Faisalabad
- 来源：CARBOHYDRATE POLYMERS 2019
- 关键词：Sustainable biosynthesis Orange peels Kinetics Curdlan Batch culture fermentation
- Power consumption, local and average volumetric mass transfer coefficient in multiple-impeller stirred bioreactors for xanthan gum solutions被引量：48收藏
- 作者：Xie, Ming-hui Xia, Jian-ye Zhou, Zhen Zhou, Guo-zhong Chu, Ju Zhuang, Ying-ping Zhang, Si-liang Noorman, Henk
- 机构：E China Univ Sci & Technol;Wenzhou Great Wall Mixer Design Inst;DSM Biotechnol Ctr
- 来源：CHEMICAL ENGINEERING SCIENCE 2014
- 关键词：Power Mass transfer Xanthan gum Non-Newtonian fluid Impeller combination
- Effects of light/dark cycle, mixing pattern and partial pressure of H2 on biohydrogen production by Rhodobacter sphaeroides ZX-5被引量：47收藏
- 作者：Li, Xu Wang, Yonghong Zhang, Siliang Chu, Ju Zhang, Ming Huang, Mingzhi Zhuang, Yingping
- 机构：E China Univ Sci & Technol
- 来源：BIORESOURCE TECHNOLOGY 2011
- 关键词：Photo-hydrogen production Rhodobacter sphaeroides Light/dark cycle Shaking velocity Hydrogen partial pressure
- Understanding the effect of foreign gene dosage on the physiology of Pichia pastoris by transcriptional analysis of key genes被引量：47收藏
- 作者：Zhu, Taicheng Guo, Meijin Zhuang, Yingping Chu, Ju Zhang, Siliang
- 机构：E China Univ Sci & Technol;Chinese Acad Sci
- 来源：APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 2011
- 关键词：Gene dosage Pichia pastoris Methanol metabolism Cell physiology mRNA quantitative analysis
