成果/Result
- Clodronate-loaded liposomal and fibroblast-derived exosomal hybrid system for enhanced drug delivery to pulmonary fibrosis被引量：157收藏
- 作者：Sun, Lingna Fan, Mingrui Huang, Dong Li, Bingqin Xu, Ruoting Gao, Feng Chen, Yanzuo
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：BIOMATERIALS 2021
- 关键词：Pulmonary fibrotic therapy Exosomes Liposomes Macrophages depletion Fibrosis penetration
- Nanodrug Delivery Systems Modulate Tumor Vessels to Increase the Enhanced Permeability and Retention Effect被引量：143收藏
- 作者：Huang, Dong Sun, Lingna Huang, Leaf Chen, Yanzuo
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Univ North Carolina
- 来源：JOURNAL OF PERSONALIZED MEDICINE 2021
- 关键词：nanoparticles tumor vascular regulation EPR effect angiogenesis blood perfusion vascular permeability
- Pluronic-based functional polymeric mixed micelles for co-delivery of doxorubicin and paclitaxel to multidrug resistant tumor被引量：116收藏
- 作者：Chen, Yanzuo Zhang, Wei Huang, Yukun Gao, Feng Sha, Xianyi Fang, Xiaoling
- 机构：E China Univ Sci & Technol;Fudan Univ;Fudan Univ;Eastern Virginia Med Sch
- 来源：INTERNATIONAL JOURNAL OF PHARMACEUTICS 2015
- 关键词：Doxorubicin Paclitaxel Codelivery Polymeric micelle Anti-cancer efficacy Multidrug resistance
- Combined Cancer Chemo-Photodynamic and Photothermal Therapy Based on ICG/PDA/TPZ-Loaded Nanoparticles被引量：108收藏
- 作者：Huang, Xiaqin Wu, Junru He, Muye Hou, Xinyu Wang, Yan Cai, Xiaoran Xin, Hongliang Gao, Feng Chen, Yanzuo
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;Nanjing Med Univ
- 来源：MOLECULAR PHARMACEUTICS 2019
- 关键词：nanoparticle chemo-photodynamic therapy photothermal therapy polydopamine indocyanine green tirapazamine Tumor
- Vasodilator Hydralazine Promotes Nanoparticle Penetration in Advanced Desmoplastic Tumors被引量：88收藏
- 作者：Chen, Yanzuo Song, Wantong Shen, Limei Qiu, Nasha Hu, Mengying Liu, Yun Liu, Qi Huang, Leaf
- 机构：Univ N Carolina;Univ N Carolina;East China Univ Sci & Technol;Chinese Acad Sci;Zhejiang Univ
- 来源：ACS NANO 2019
- 关键词：hydralazine nanoparticles tumor penetration desmoplastic tumor tumor microenvironment
- The preparation, characterization, and pharmacokinetic studies of chitosan nanoparticles loaded with paclitaxel/dimethyl-β-cyclodextrin inclusion complexes被引量：57收藏
- 作者：Ye, Ya-Jing Wang, Yun Lou, Kai-Yan Chen, Yan-Zuo Chen, Rongjun Gao, Feng
- 机构：E China Univ Sci & Technol;Univ London Imperial Coll Sci Technol & Med;E China Univ Sci & Technol;E China Univ Sci & Technol
- 来源：INTERNATIONAL JOURNAL OF NANOMEDICINE 2015
- 关键词：dimethyl-beta-cyclodextrin inclusion complex chitosan nanoparticles drug delivery sustained release paclitaxel
- Vitamin E Succinate-Grafted-Chitosan Oligosaccharide/RGD-Conjugated TPGS Mixed Micelles Loaded with Paclitaxel for U87MG Tumor Therapy被引量：45收藏
- 作者：Chen, Yanzuo Feng, Shu Liu, Wenchao Yuan, Zeting Yin, Peihao Gao, Feng
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Shanghai Univ Tradit Chinese Med
- 来源：MOLECULAR PHARMACEUTICS 2017
- 关键词：VES-grafted-CSO TPGS-RGD PTX mixed micelles U87MG tumor inhibition
- Preparation and characterization of mPEG grafted chitosan micelles as 5-fluorouracil carriers for effective anti-tumor activity被引量：44收藏
- 作者：Fu, Dong-Jun Jin, Yu Xie, Mu-Qing Ye, Ya-Jing Qin, Dong-Dong Lou, Kai-Yan Chen, Yan-Zuo Gao, Feng
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol;E China Univ Sci & Technol
- 来源：CHINESE CHEMICAL LETTERS 2014
- 关键词：Self-assembled micelles Methoxy polyethylene glycol grafted chitosan 5-Fluorouracil Controlled-release
- Cyclodextrin/chitosan nanoparticles for oral ovalbumin delivery: Preparation, characterization and intestinal mucosal immunity in mice被引量：43收藏
- 作者：He, Muye Zhong, Chen Hu, Huibing Jin, Yu Chen, Yanzuo Lou, Kaiyan Gao, Feng
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：ASIAN JOURNAL OF PHARMACEUTICAL SCIENCES 2019
- 关键词：beta-cyclodextrin Chitosan nanoparticles Ovalbumin Oral protein delivery Intestinal mucosal immunity
- Clodronate-nintedanib-loaded exosome-liposome hybridization enhances the liver fibrosis therapy by inhibiting Kupffer cell activity被引量：40收藏
- 作者：Ji, Keqin Fan, Mingrui Huang, Dong Sun, Lingna Li, Bingqin Xu, Ruoting Zhang, Jiajing Shao, Xuan Chen, Yanzuo
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：BIOMATERIALS SCIENCE 2022
- 关键词：Antigen-antibody reactions - Cell culture - Controlled drug delivery - Liver - Macrophages - Targeted drug delivery
- RETRACTED: c(RGDyK)-decorated Pluronic micelles for enhanced doxorubicin and paclitaxel delivery to brain glioma (Retracted Article)被引量：39收藏
- 作者：Huang, Yukun Liu, Wenchao Gao, Feng Fang, Xiaoling Chen, Yanzuo
- 机构：E China Univ Sci & Technol;Minist Educ;Fudan Univ
- 来源：INTERNATIONAL JOURNAL OF NANOMEDICINE 2016
- 关键词：Pluronic micelles integrin blood-brain barrier brain glioma targeted delivery
- Dual-functional c(RGDyK)-decorated Pluronic micelles designed for antiangiogenesis and the treatment of drug-resistant tumor被引量：29收藏
- 作者：Chen, Yanzuo Zhang, Wei Huang, Yukun Gao, Feng Fang, Xiaoling
- 机构：E China Univ Sci & Technol;Fudan Univ;Fudan Univ;Eastern Virginia Med Sch
- 来源：INTERNATIONAL JOURNAL OF NANOMEDICINE 2015
- 关键词：dual-functional micelles c(RGDyK) antiangiogenesis multidrug resistance
- Novel nanoparticles composed of chitosan and β-cyclodextrin derivatives as potential insoluble drug carrier被引量：29收藏
- 作者：Chen, Yan-Zuo Huang, Yu-Kun Chen, Yuan Ye, Ya-Jing Lou, Kai-Yan Gao, Feng
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol;E China Univ Sci & Technol;Shanghai Inst Hlth Sci
- 来源：CHINESE CHEMICAL LETTERS 2015
- 关键词：Chitosan Cyclodextrin derivatives Ionic gelation method Drug delivery system
- In Vivo Biodistribution and Anti-Tumor Efficacy Evaluation of Doxorubicin and Paclitaxel-Loaded Pluronic Micelles Decorated with c(RGDyK) Peptide被引量：25收藏
- 作者：Chen, Yanzuo Zhang, Wei Huang, Yukun Gao, Feng Fang, Xiaoling
- 机构：E China Univ Sci & Technol;Fudan Univ;Fudan Univ;Fudan Univ;Eastern Virginia Med Sch
- 来源：PLOS ONE 2016
- RETRACTED: The therapeutic effect of methotrexate-conjugated Pluronic-based polymeric micelles on the folate receptor-rich tumors treatment (Retracted Article)被引量：24收藏
- 作者：Chen, Yanzuo Zhang, Wei Huang, YuKun Gao, Feng Sha, Xianyi Lou, Kaiyan Fang, Xiaoling
- 机构：E China Univ Sci & Technol;Fudan Univ;Fudan Univ;Fudan Univ;Eastern Virginia Med Sch
- 来源：INTERNATIONAL JOURNAL OF NANOMEDICINE 2015
- 关键词：methotrexate-conjugated mixed micelles folate receptor Pluronic KBv cells
- Biological Hyperthermia-Inducing Nanoparticles for Specific Remodeling of the Extracellular Matrix Microenvironment Enhance Pro-Apoptotic Therapy in Fibrosis被引量：24收藏
- 作者：Zhang, Jinru Ji, Keqin Ning, Yuanmeng Sun, Lingna Fan, Mingrui Shu, Chunjie Zhang, Ziqi Tu, Tianyu Cao, Jingyun Gao, Feng Chen, Yanzuo
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：ACS NANO 2023
- 关键词：fibrosis exosome and liposome hybrid nanoparticles hyperthermia 2 4-dinitrophenol remodelingof the extracellular matrix microenvironment
- β-Cyclodextrin-Based Inclusion Complexation Bridged Biodegradable Self-Assembly Macromolecular Micelle for the Delivery of Paclitaxel被引量：23收藏
- 作者：Chen, Yanzuo Huang, Yukun Qin, Dongdong Liu, Wenchao Song, Chao Lou, Kaiyan Wang, Wei Gao, Feng
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol;E China Univ Sci & Technol;E China Univ Sci & Technol;E China Univ Sci & Technol
- 来源：PLOS ONE 2016
- Targeting integrin-rich tumors with temoporfin-loaded vitamin-E-succinate-grafted chitosan oligosaccharide/D-α-tocopheryl polyethylene glycol 1000 succinate nanoparticles to enhance photodynamic therapy efficiency被引量：20收藏
- 作者：Wu, Junru Feng, Shu Liu, Wenchao Gao, Feng Chen, Yanzuo
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：INTERNATIONAL JOURNAL OF PHARMACEUTICS 2017
- 关键词：Temoporfin Photodynamic therapy Nanoparticles Tumor targeting
- Tofacitinib Citrate Coordination-Based Dual-Responsive/Scavenge Nanoplatform Toward Regulate Colonic Inflammatory Microenvironment for Relieving Colitis被引量：16收藏
- 作者：Zou, Jiafeng Jiang, Kun Chen, You Ma, Ying Xia, Chuanhe Ding, Wenxing Yao, Min Lin, Yiting Chen, Yanzuo Zhao, Yuzheng Gao, Feng
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Chinese Acad Med Sci;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：ADVANCED HEALTHCARE MATERIALS 2024
- 关键词：colitis colonic inflammatory microenvironment coordination nanoplatform dual-responsive dual-scavenge tofacitinib citrate
- 提高学生学习药用高分子材料学课程积极性的探索被引量：15收藏
- 作者：高峰 陈彦佐 楼开炎
- 机构：华东理工大学药学院
- 来源：《药学教育》 2016
- 关键词：药用高分子材料学 教学方法 教学技巧
- 摘要：药用高分子材料学是药物制剂专业的主干课程之一。为提高学生学习药用高分子材料学课程的积极性,提高教学效率,达到多角度提升学生素质的目标,从教学技巧的运用和改进教学方法两个方面进行教学改革探讨。
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- Vitamin E succinate-grafted-chitosan/chitosan oligosaccharide mixed micelles loaded with C-DMSA for Hg2+ detection and detoxification in rat liver被引量：7收藏
- 作者：Wei, Binghui He, Muye Cai, Xiaoran Hou, Xinyu Wang, Yujie Chen, Jiaojiao Lan, Minbo Chen, Yanzuo Lou, Kaiyan Gao, Feng
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：INTERNATIONAL JOURNAL OF NANOMEDICINE 2019
- 关键词：micelles C-DMSA mercury poisoning detection and detoxification drug delivery system
- An anti-miR-301a and zinc coordination driven nanozyme loaded in nanoparticle for oral therapy of inflammatory bowel disease based on colitis microenvironment regulation被引量：6收藏
- 作者：Zou, Jiafeng Xia, Chuanhe Yao, Min Pan, Xier Zheng, Shulei Lin, Yiting Zhao, Xinlin Wang, Yanwen Chen, Yanzuo Lan, Minbo Wang, Junshan Gao, Feng
- 机构：East China Univ Sci & Technol;Tongji Univ;Bengbu First Peoples Hosp;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：CHEMICAL ENGINEERING JOURNAL 2025
- 关键词：Coordination driven nanozyme Anti-miR-301a Zinc Colitis microenvironment regulation Inflammatory bowel disease Oral nanoparticle
- 对工业药剂学教学改革的探讨被引量：4收藏
- 作者：高峰 陈彦佐 任福正 翁伟宇 景秋芳 崔景斌
- 机构：华东理工大学药学院药剂学教研室
- 来源：《化工高等教育》 2014
- 关键词：工业药剂学 教学改革 教学方法
- 摘要：工业药剂学是一门实践性很强的学科,在药学相关专业中占有十分重要的地位。如何培养适应社会发展的高素质医药人才是许多教学工作者始终重视的问题。本文对工业药剂学的教学改革进行了全面的探讨。
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- Rapamycin and Hyperoside-Co-loaded Macrophage Delivery System Enhanced Pulmonary Fibrosis Therapy by Autophagy Upregulation and Epithelial-to-Mesenchymal Transition Inhibition被引量：4收藏
- 作者：Wang, Qi Ning, Yuanmeng Zhang, Jinru Du, Xu Xu, Zihan Hu, Yongcheng Gao, Feng Chen, Yanzuo
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：ACS APPLIED MATERIALS & INTERFACES 2024
- 关键词：pulmonary fibrosis autophagy epithelial-to-mesenchymaltransition macrophage drug delivery system extracellulartraps
- 药物制剂专业实验的教学探讨被引量：3收藏
- 作者：高峰 陈彦佐 任福正 翁伟宇 景秋芳 崔景斌
- 机构：华东理工大学药学院药物制剂教研室
- 来源：《实验室研究与探索》 2014
- 关键词：药物制剂 实验教学 教学模式
- 摘要：药物制剂专业实验是注重培养学生对于药物的剂型设计、工艺优化、质量控制和合理应用的一门应用性和实践性课程。药物制剂教研室针对传统药物制剂实验教学现状的不足之处,从改善教学模式、提高实验课科研含量并培养学生科研设计能力、加强...
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- 基于大学生创新实验的药物制剂专业人才培养被引量：2收藏
- 作者：高峰 陈彦佐 楼开炎
- 机构：华东理工大学药学院
- 来源：《药学教育》 2015
- 关键词：药物制剂 人才培养 大学生创新实验
- 摘要：大学生创新实验在激发大学生创新意识、培养大学生科研能力等方面具有非常重要的意义。基于教研组所做的工作,总结在实施大学生创新实验过程中药物制剂专业人才培养的办法、效果与经验,并且围绕如何能够更好地提高项目执行效率、调动教师...
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- Dual-functional C(RGDYK)-decorated pluronic micelles for antiangiogenesis and drug resistant tumor treatment in vitro被引量：2收藏
- 作者：Chen, Yanzuo Gao, Feng Sha, Xianyi Fang, Xiaoling
- 机构：E China Univ Sci & Technol;Fudan Univ;Fudan Univ
- 来源：NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE 2016
- Exosome-liposome hybrid system with antioxidant and anti-inflammatory activities targeting glial cells for the treatment of central nervous system diseases被引量：1收藏
- 作者：Chen, Yutong Guo, Shuting Fan, Mingrui Yang, Songlin Lin, Qiuxia Zou, Jiafeng Xu, Junyuan Zheng, Tongtong He, Kangtai Gao, Feng Chen, Yanzuo
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：CHINESE CHEMICAL LETTERS 2026
- 关键词：Central nervous system disease Glial cells Exosome-liposome hybrid system Fisetin Pioglitazone
- Clodronate-nintedanib-loaded exosome-liposome hybridization enhances the liver fibrosis therapy by inhibiting Kupffer cell activity (vol 10, pg 702, 2022)被引量：0收藏
- 作者：Ji, Keqin Fan, Mingrui Huang, Dong Sun, Lingna Li, Bingqin Xu, Ruoting Zhang, Jiajing Shao, Xuan Chen, Yanzuo
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：BIOMATERIALS SCIENCE 2024
- 药物制剂专业由工科向理科转型的探索被引量：0收藏
- 作者：高峰 陈彦佐
- 机构：华东理工大学药学院;上海市功能性材料化学重点实验室;上海市新药设计重点实验室
- 来源：《药学教育》 2014
- 关键词：药物制剂 专业建设 专业发展 学科转型
- 摘要：药物制剂作为一个应用性强的专业,越来越为社会所重视。根据国家教育部规定,全国开设的药物制剂专业均应定位于理科专业,药物制剂专业需由工科向理科进行转型。结合学校药物制剂专业的现状,从培养方案、师资队伍、教学改革与教学研究、...
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