成果/Result
- admetSAR: A Comprehensive Source and Free Tool for Assessment of Chemical ADMET Properties被引量：1485收藏
- 作者：Cheng, Feixiong Li, Weihua Zhou, Yadi Shen, Jie Wu, Zengrui Liu, Guixia Lee, Philip W. Tang, Yun
- 机构：E China Univ Sci & Technol
- 来源：JOURNAL OF CHEMICAL INFORMATION AND MODELING 2012
- 关键词：Industrial chemicals - Classification (of information) - Regression analysis - Consumer products - Indicators (chemical) - Additives - Chemical contamination - Database systems
- Prediction of Drug-Target Interactions and Drug Repositioning via Network-Based Inference被引量：626收藏
- 作者：Cheng, Feixiong Liu, Chuang Jiang, Jing Lu, Weiqiang Li, Weihua Liu, Guixia Zhou, Weixing Huang, Jin Tang, Yun
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol
- 来源：PLOS COMPUTATIONAL BIOLOGY 2012
- 关键词：Cell culture - Complex networks - Computation theory - Drug interactions - Tensors
- Recent Advances in the Chemical Synthesis of C-Glycosides被引量：551收藏
- 作者：Yang, You Yu, Biao
- 机构：East China Univ Sci & Technol;Chinese Acad Sci
- 来源：CHEMICAL REVIEWS 2017
- 关键词：Glycosylation - Synthesis (chemical) - Cycloaddition - Metal complexes - Transition metals - Transition metal compounds
- Organocatalysis: asymmetric cascade reactions catalysed by chiral secondary amines被引量：482收藏
- 作者：Yu, Xinhong Wang, Wei
- 机构：Univ New Mexico;E China Univ Sci & Technol
- 来源：ORGANIC & BIOMOLECULAR CHEMISTRY 2008
- 关键词：Rate constants - Amines
- Graphene Oxide as a Matrix for Enzyme Immobilization被引量：466收藏
- 作者：Zhang, Jiali Zhang, Feng Yang, Haijun Huang, Xuelei Liu, Hui Zhang, Jingyan Guo, Shouwu
- 机构：E China Univ Sci & Technol;Shanghai Jiao Tong Univ
- 来源：LANGMUIR 2010
- 关键词：Atomic force microscopy - Molecules - Catalyst activity - Graphene - Surface treatment
- Photo-Fenton Reaction of Graphene Oxide: A New Strategy to Prepare Graphene Quantum Dots for DNA Cleavage被引量：463收藏
- 作者：Zhou, Xuejiao Zhang, Yan Wang, Chong Wu, Xiaochen Yang, Yongqiang Zheng, Bin Wu, Haixia Guo, Shouwu Zhang, Jingyan
- 机构：Shanghai Jiao Tong Univ;E China Univ Sci & Technol
- 来源：ACS NANO 2012
- 关键词：photo-Fenton reaction graphene quantum dot DNA cleavage
- A Highly Sensitive and Selective OFF-ON Fluorescent Sensor for Cadmium in Aqueous Solution and Living Cell被引量：331收藏
- 作者：Cheng, Tanyu Xu, Yuifang Zhang, Shenyi Zhu, Weiping Qian, Xuhong Duan, Liping
- 机构：E China Univ Sci & Technol
- 来源：JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 2008
- FRET-Based Mito-Specific Fluorescent Probe for Ratiometric Detection and Imaging of Endogenous Peroxynitrite: Dyad of Cy3 and Cy5被引量：316收藏
- 作者：Jia, Xiaotong Chen, Qiangqiang Yang, Yingfang Tang, Yao Wang, Rui Xu, Yufang Zhu, Weiping Qian, Xuhong
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 2016
- 关键词：Fluorescence spectroscopy - Probes
- Mitochondrial copper depletion suppresses triple-negative breast cancer in mice被引量：304收藏
- 作者：Cui, Liyang Gouw, Arvin M. LaGory, Edward L. Guo, Shenghao Attarwala, Nabeel Tang, Yao Qi, Ji Chen, Yun-Sheng Gao, Zhou Casey, Kerriann M. Bazhin, Arkadiy A. Chen, Min Hu, Leeann Xie, Jinghang Fang, Mingxi Zhang, Cissy Zhu, Qihua Wang, Zhiyuan Giaccia, Amato J. Gambhir, Sanjiv Sam Zhu, Weiping Felsher, Dean W. Pegram, Mark D. Goun, Elena A. Le, Anne Rao, Jianghong
- 机构：Stanford Univ;Stanford Univ;Stanford Univ;Stanford Univ;Johns Hopkins Univ
- 来源：NATURE BIOTECHNOLOGY 2021
- 关键词：Mammals - Mitochondria - Phosphorylation - Cancer cells - Diseases - Pathology - Metabolism - Cell death - Chelation
- Reducing Graphene Oxide via Hydroxylamine: A Simple and Efficient Route to Graphene被引量：298收藏
- 作者：Zhou, Xuejiao Zhang, Jiali Wu, Haixia Yang, Haijun Zhang, Jingyan Guo, Shouwu
- 机构：E China Univ Sci & Technol;Shanghai Jiao Tong Univ
- 来源：JOURNAL OF PHYSICAL CHEMISTRY C 2011
- 关键词：Cost reduction - Amines - Cost effectiveness - Crystalline materials
- Fluorescent Probes for the Detection of Hydrogen Sulfide in Biological Systems被引量：269收藏
- 作者：Xuan, Weimin Sheng, Chunquan Cao, Yanting He, Wenhan Wang, Wei
- 机构：Second Mil Med Univ;Univ New Mexico;E China Univ Sci & Technol
- 来源：ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 2012
- 关键词：azides fluorescEIn fluorescent probes hydrogen sulfide rhodamines
- Estimation of ADME Properties with Substructure Pattern Recognition被引量：269收藏
- 作者：Shen, Jie Cheng, Feixiong Xu, You Li, Weihua Tang, Yun
- 机构：E China Univ Sci & Technol
- 来源：JOURNAL OF CHEMICAL INFORMATION AND MODELING 2010
- 关键词：Support vector machines - Chemical analysis
- A dual-response BODIPY-based fluorescent probe for the discrimination of glutathione from cystEIn and homocystEIn被引量：264收藏
- 作者：Wang, Feiyi Zhou, Li Zhao, Chunchang Wang, Rui Fei, Qiang Luo, Sihang Guo, Zhiqian Tian, He Zhu, Wei-Hong
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol;E China Univ Sci & Technol
- 来源：CHEMICAL SCIENCE 2015
- 关键词：Cyclization - Probes - Covalent bonds - Fluorescence imaging - Peptides - Sulfur compounds
- Ratiometric and highly selective fluorescent sensor for cadmium under physiological pH range: A new strategy to discriminate cadmium from zinc被引量：253收藏
- 作者：Lu, Chunliang Xu, Zhaochao Cui, Jingnan Zhang, Rong Qian, Xuhong
- 机构：Dalian Univ Technol;E China Univ Sci & Technol
- 来源：JOURNAL OF ORGANIC CHEMISTRY 2007
- 关键词：Cadmium compounds - Charge transfer - Complexation - pH effects - Physiology - Zinc
- Organocatalytic enantioselective conjugate additions to enones被引量：250收藏
- 作者：Wang, Jian Li, Hao Zu, Liansuo Jiang, Wei Xie, Hexin Duan, Wenhu Wang, Wei
- 机构：E China Univ Sci & Technol;Univ New Mexico
- 来源：JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 2006
- Visualizing RNA dynamics in live cells with bright and stable fluorescent RNAs被引量：249收藏
- 作者：Chen, Xianjun Zhang, Dasheng Su, Ni Bao, Bingkun Xie, Xin Zuo, Fangting Yang, Lipeng Wang, Hui Jiang, Li Lin, Qiuning Fang, Mengyue Li, Ningfeng Hua, Xin Chen, Zhengda Bao, Chunyan Xu, Jinjin Du, Wenli Zhang, Lixin Zhao, Yuzheng Zhu, Linyong Loscalzo, Joseph Yang, Yi
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Chinese Acad Sci;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：NATURE BIOTECHNOLOGY 2019
- 关键词：Cells - Enzyme kinetics - Fluorescence - Mammals - Cytology
- Target identification among known drugs by deep learning from heterogeneous networks被引量：244收藏
- 作者：Zeng, Xiangxiang Zhu, Siyi Lu, Weiqiang Liu, Zehui Huang, Jin Zhou, Yadi Fang, Jiansong Huang, Yin Guo, Huimin Li, Lang Trapp, Bruce D. Nussinov, Ruth Eng, Charis Loscalzo, Joseph Cheng, Feixiong
- 机构：Hunan Univ;Xiamen Univ;East China Normal Univ;East China Normal Univ;East China Univ Sci & Technol
- 来源：CHEMICAL SCIENCE 2020
- 关键词：Network embeddings - Deep learning - Genome
- Indicator displacement assays (IDAs): the past, present and future被引量：241收藏
- 作者：Sedgwick, Adam C. Brewster, James T., II Wu, Tianhong Feng, Xing Bull, Steven D. Qian, Xuhong Sessler, Jonathan L. James, Tony D. Anslyn, Eric V. Sun, Xiaolong
- 机构：Univ Texas Austin;Xi An Jiao Tong Univ;Univ Bath;East China Univ Sci & Technol;East China Normal Univ
- 来源：CHEMICAL SOCIETY REVIEWS 2021
- 关键词：Assays - Enantioselectivity
- Assembly of Graphene Oxide-Enzyme Conjugates through Hydrophobic Interaction被引量：237收藏
- 作者：Zhang, Yan Zhang, Jingyan Huang, Xuelei Zhou, Xuejiao Wu, Haixia Guo, Shouwu
- 机构：E China Univ Sci & Technol;Shanghai Jiao Tong Univ
- 来源：SMALL 2012
- 关键词：enzyme adsorption chemically reduced graphene oxide hydrophobic interaction horseradish peroxidase oxalate oxidase
- Graphene quantum dots/gold electrode and its application in living cell H2O2 detection被引量：236收藏
- 作者：Zhang, Yan Wu, Congyu Zhou, Xuejiao Wu, Xiaochen Yang, Yongqiang Wu, Haixia Guo, Shouwu Zhang, Jingyan
- 机构：Shanghai Jiao Tong Univ;E China Univ Sci & Technol
- 来源：NANOSCALE 2013
- 关键词：Graphene - Semiconductor quantum dots - Gold compounds - Nanocrystals
- Enhancing the Enrichment of Pharmacophore-Based Target Prediction for the Polypharmacological Profiles of Drugs被引量：236收藏
- 作者：Wang, Xia Pan, Chenxu Gong, Jiayu Liu, Xiaofeng Li, Honglin
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol
- 来源：JOURNAL OF CHEMICAL INFORMATION AND MODELING 2016
- 关键词：Drug interactions - Probability distributions - Query processing - Forecasting
- A water-soluble boronate-based fluorescent probe for the selective detection of peroxynitrite and imaging in living cells被引量：205收藏
- 作者：Sun, Xiaolong Xu, Qingling Kim, Gyoungmi Flower, Stephen E. Lowe, John P. Yoon, Juyoung Fossey, John S. Qian, Xuhong Bull, Steven D. James, Tony D.
- 机构：Univ Bath;Ewha Womans Univ;Univ Birmingham;E China Univ Sci & Technol
- 来源：CHEMICAL SCIENCE 2014
- 关键词：Fructose - Lanthanum compounds - Cytology - Fluorescence - Fluorescence spectroscopy
- Horseradish Peroxidase Immobilized on Graphene Oxide: Physical Properties and Applications in Phenolic Compound Removal被引量：198收藏
- 作者：Zhang, Feng Zheng, Bin Zhang, Jiali Huang, Xuelei Liu, Hui Guo, Shouwu Zhang, Jingyan
- 机构：Shanghai Jiao Tong Univ;E China Univ Sci & Technol
- 来源：JOURNAL OF PHYSICAL CHEMISTRY C 2010
- 关键词：Catalyst activity - Enzyme activity - Food products - Phenols - Enzyme immobilization - Physical properties - Substrates - Graphene
- Regulation of non-canonical DNA structures by small molecules and carbon materials被引量：197收藏
- 作者：Wang, Chong Zhang, Jingyan Guo, Shouwu
- 机构： State Key Laboratory of Bioreactor Engineering; Research Institute of Micro/Nano Science and Technology
- 来源：RSC Green Chemistry 2015
- Qualitative and quantitative analysis in quality control of traditional Chinese medicines被引量：193收藏
- 作者：Liang, Xin-miao Jin, Yu Wang, Yan-ping Jin, Gao-wa Fu, Qing Xiao, Yuan-sheng
- 机构：Chinese Acad Sci;E China Univ Sci & Technol
- 来源：JOURNAL OF CHROMATOGRAPHY A 2009
- 关键词：Traditional Chinese medicines (TCMs) Quality control Qualitative analysis Quantitative analysis Fingerprint analysis
- Insight into the Cellular Internalization and Cytotoxicity of Graphene Quantum Dots被引量：185收藏
- 作者：Wu, Congyu Wang, Chong Han, Ting Zhou, Xuejiao Guo, Shouwu Zhang, Jingyan
- 机构：Shanghai Jiao Tong Univ;E China Univ Sci & Technol
- 来源：ADVANCED HEALTHCARE MATERIALS 2013
- 关键词：cellular internalization cytotoxicity distribution graphene quantum dots
- Fluorescent In Situ Targeting Probes for Rapid Imaging of Ovarian-Cancer-Specific γ-Glutamyltranspeptidase被引量：184收藏
- 作者：Wang, Feiyi Zhu, Ying Zhou, Li Pan, Liang Cui, Zhifen Fei, Qiang Luo, Sihang Pan, Dun Huang, Qing Wang, Rui Zhao, Chunchang Tian, He Fan, Chunhai
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol;Chinese Acad Sci;E China Univ Sci & Technol
- 来源：ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 2015
- 关键词：aromatic hydrocarbon transfer enzymes fluorescence photophysics tumor cells
- Tailored Engineering of Novel Xanthonium Polymethine Dyes for Synergetic PDT and PTT Triggered by 1064 nm Laser toward Deep-Seated Tumors被引量：183收藏
- 作者：Bian, Hui Ma, Dandan Zhang, Xinfu Xin, Kai Yang, Youjun Peng, Xiaojun Xiao, Yi
- 机构：Dalian Univ Technol;East China Univ Sci & Technol
- 来源：SMALL 2021
- 关键词：deep‐ seated tumors NIR‐ II PDT NIR‐ II PTT small molecules xanthonium polymethine dye
- Stereoselective Synthesis of Planar Chiral Ferrocenes被引量：182收藏
- 作者：Deng, Wei-Ping Snieckus, Victor Metallinos, Costa
- 机构： East China University of Science and Technology; Queen's University; Brock University
- 来源：Chiral Ferrocenes in Asymmetric Catalysis: Synthesis and Applications 2010
- 关键词：Enantioselectivity - Organometallics
- An Artificial Molecular Shuttle Operates in Lipid Bilayers for Ion Transport被引量：182收藏
- 作者：Chen, Sujun Wang, Yichuan Nie, Ting Bao, Chunyan Wang, Chenxi Xu, Tianyi Lin, Qiuning Qu, Da-Hui Gong, Xueqing Yang, Yi Zhu, Linyong Tian, He
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 2018
- 关键词：Molecular electronics - Ion exchange - Ions - Stochastic systems
