成果/Result
- Mixed bacteria-loaded biochar for the immobilization of arsenic, lead, and cadmium in a polluted soil system: Effects and mechanisms被引量：97收藏
- 作者：Ji, Xiaowen Wan, Jiang Wang, Xuedong Peng, Cheng Wang, Gehui Liang, Weiyu Zhang, Wei
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：SCIENCE OF THE TOTAL ENVIRONMENT 2022
- 关键词：Biochar Soil Heavy metals Mixed bacteria-loaded biochar Mechanisms
- Immobilization of Ni (Ⅱ) at three levels of contaminated soil by rhamnolipids modified nano zero valent iron (RL@nZVI): Effects and mechanisms被引量：59收藏
- 作者：Sang, Li Wang, Gehui Liu, Lin Bian, Hao Jiang, Lingling Wang, Huadong Zhang, Yinjie Zhang, Wei Peng, Cheng Wang, Xuedong
- 机构： State Environmental Protection Key Laboratory of Environmental Risk Assessment and Control on Chemical Process; Shanghai Institute of Pollution Control and Ecological Security; State Key Laboratory of Bioreactor Engineering
- 来源：Chemosphere 2021
- 关键词：Iron oxides - Surface active agents - Hydrogen bonds - Synthesis (chemical) - Remediation - Soil pollution - Soils - Carboxylation - Binary alloys
- Improving the mda-7/IL-24 refolding and purification process using optimized culture conditions based on the structure characteristics of inclusion bodies被引量：33收藏
- 作者：Wang, Xiaojuan Bai, Chaogang Zhang, Jian Sun, Aiyou Wang, Xuedong Wei, Dongzhi
- 机构： State Key Laboratory of Bioreactor Engineering
- 来源：Bioresources and Bioprocessing 2014
- 关键词：Cell death - Metal ions - Metals - Purification - Scanning electron microscopy - Solubility
- Disparity in productive binding mode of the slow-reacting enantiomer determines the novel catalytic behavior of Candida antarctica lipase B被引量：33收藏
- 作者：Xu, Tao Zhang, Lujia Su, Erzheng Cui, Dongbing Wang, Xuedong Wei, Dongzhi
- 机构： State Key Laboratory of Bioreactor Engineering
- 来源：Journal of Molecular Catalysis B: Enzymatic 2010
- 关键词：Candida - Enzymes - Yeast - Reaction kinetics - Molecular modeling - Binding energy - Enantioselectivity - Reaction intermediates - Substrates - Enantiomers
- 脂肪酶 RWL 催化合成二氢燕麦生物碱 D被引量：27收藏
- 作者：Chen, Jinbo Zhai, Chuntao Jin, Minrong Wu, Qian Yuan, Minjia Wang, Xuedong Ren, Yuhong Wang, Hualei
- 机构： School of Biotechnology; Shanghai Zhina Biotechnology Co.; Shanghai Qiran Biotechnology Co.; Shanghai Jinjia Technology Co.
- 来源：[1] School of Biotechnology, East China University of Science and Technology, Shanghai, 200237, China; [2] Shanghai Zhina Biotechnology Co., Ltd., Shanghai, 201400, China; [3] Shanghai Qiran Biotechnology Co., Ltd., Shanghai, 201702, China; [4] Shanghai Jinjia Technology Co., Ltd., Shanghai, 201210, China 2026
- Enhanced Steroid Metabolites Production by Resting Cell Phytosterol Bioconversion被引量：24收藏
- 作者：Gao, X. -Q. Feng, J. -X. Wang, X. -D. Hua, Q. Wei, D. -Z.
- 机构：E China Univ Sci & Technol
- 来源：CHEMICAL AND BIOCHEMICAL ENGINEERING QUARTERLY 2015
- 关键词：phytosterol steroid metabolites resting cell bioconversion hydroxypropyl-beta-cyclodextrin optimization
- Oxygen vectors used for S-adenosylmethionine production in recombinant Pichia pastoris with sorbitol as supplemental carbon source被引量：24收藏
- 作者：Zhang, Jian-Guo Wang, Xue-Dong Zhang, Ji-Ning Wei, Dong-Zhi
- 机构： State Key Laboratory of Bioreactor Engineering
- 来源：Journal of Bioscience and Bioengineering 2008
- 关键词：Drug products - Fermentation - Metabolism - Organic carbon - Oxygen - Production control
- ProtEIn Engineering of a Nitrilase from Burkholderia cenocepacia J2315 for Efficient and Enantioselective Production of (R)-o-Chloromandelic Acid被引量：23收藏
- 作者：Wang, Hualei Gao, Wenyuan Sun, Huihui Chen, Lifeng Zhang, Lujia Wang, Xuedong Wei, Dongzhi
- 机构：E China Univ Sci & Technol
- 来源：APPLIED AND ENVIRONMENTAL MICROBIOLOGY 2015
- 关键词：Hydrolysis - Genetic engineering - Biochemical engineering - Mutagenesis - ProtEIns
- The influence of hydroxypropyl-β-cyclodextrin on the enantioselective hydrolysis of 2-amino phenylpropionitrile catalyzed by recombinant nitrilase被引量：21收藏
- 作者：Li, Ming-Yang Wang, Xue-Dong
- 机构： State Key Laboratory of Bioreactor Engineering
- 来源：Bioresources and Bioprocessing 2014
- 关键词：Amino acids - Biochemistry - Cyclodextrins - Hydrolysis - Hydrophobicity - Substrates
- Investigation of factors affecting biotransformation of phytosterols to 9-hydroxyandrost-4-ene-3,-17-dione based on the HP-β-CD-resting cells reaction system被引量：21收藏
- 作者：Gao, Xingqiang Feng, Jianxun Hua, Qiang Wei, Dongzhi Wang, Xuedong
- 机构：E China Univ Sci & Technol
- 来源：BIOCATALYSIS AND BIOTRANSFORMATION 2014
- 关键词：Biotransformation hydroxypropyl-beta-cyclodextrin Mycobacterium phytosterols rate limitation
- Mixed bacteria passivation for the remediation of arsenic, lead, and cadmium: Medium optimization and mechanisms被引量：20收藏
- 作者：Peng, Cheng Zhao, Xuan Ji, Xiaowen Wu, Jinhong Liang, Weiyu Song, Huihui Zhang, Wei Wang, Xuedong
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Shanghai Yaxin Urban Construction Co Ltd
- 来源：PROCESS SAFETY AND ENVIRONMENTAL PROTECTION 2023
- 关键词：Mixed bacteria Bacillus Optimization Heavy metal Bioremediation
- A new fermentation strategy for S-adenosylmethionine production in recombinant Pichia pastoris被引量：19收藏
- 作者：Zhang, Jianguo Wang, Xuedong Su, Erzheng Fang, Guochen Ren, Yuhong Wei, Dongzhi
- 机构： State Key Laboratory of Bioreactor Engineering
- 来源：Biochemical Engineering Journal 2008
- 关键词：Cytology - Yeast - Fermentation - Bottles - Cells
- Effect of organic cosolvent on kinetic resolution of tert-leucine by penicillin G acylase from Kluyvera citrophila被引量：19收藏
- 作者：Liu, Shu-Lai Wei, Dong-Zhi Song, Qing-Xun Zhang, Ye-Wang Wang, Xue-Dong
- 机构： State Key Lab. of Bioreactor Engineering
- 来源：Bioprocess and Biosystems Engineering 2006
- 关键词：Enzymes - Hydrolysis - Organic solvents - Permittivity - Solutions
- High-level production of bovine enterokinase light chain using fed-batches by recombinant Pichia pastoris被引量：18收藏
- 作者：Zhang, J.-G. Wang, X.-D. Mao, X.-Z. Wei, D.-Z.
- 机构： State Key Laboratory of Bioreactor Engineering
- 来源：Chemical and Biochemical Engineering Quarterly 2009
- 关键词：Bioreactors - Mammals - Cells - Chains - Cytology - Yeast
- A novel nitrilase from Rhodobacter sphaeroides LHS-305: cloning, heterologous expression and biochemical characterization被引量：17收藏
- 作者：Wang, Hualei Li, Guinan Li, Mingyang Wei, Dongzhi Wang, Xuedong
- 机构：E China Univ Sci & Technol
- 来源：WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY 2014
- 关键词：Nitrilase Rhodobacter sphaeroides 3-Cyanopyridine Substrate specificity Regioselectivity
- A light-switchable bidirectional expression system in filamentous fungus Trichoderma reesEI被引量：15收藏
- 作者：Zhang, Guoxiu Liu, Pei Wei, Wei Wang, Xuedong Wei, Dongzhi Wang, Wei
- 机构：East China Univ Sci & Technol
- 来源：JOURNAL OF BIOTECHNOLOGY 2016
- 关键词：Trichoderma reesEI Light-switchable system Heterologous protEIn Simultaneous expression Cellulase-free background
- Influence of temperature on nucleus degradation of 4-androstene-3, 17-dione in phytosterol biotransformation by Mycobacterium sp.被引量：14收藏
- 作者：Xu, X. W. Gao, X. Q. Feng, J. X. Wang, X. D. Wei, D. Z.
- 机构：E China Univ Sci & Technol
- 来源：LETTERS IN APPLIED MICROBIOLOGY 2015
- 关键词：3-ketosteroid-9-hydroxylase 3-ketosteroid-(1)-dehydrogenase AD and or ADD production biodegradation Mycobacterium phytosterol temperature effect
- Enhancing yield of S-adenosylmethionine in Pichia pastoris by controlling NH4 + concentration被引量：13收藏
- 作者：Zhang, Jianguo Wang, Xuedong Zheng, Yu Fang, Guochen Wei, Dongzhi
- 机构： State Key Laboratory of Bioreactor Engineering
- 来源：Bioprocess and Biosystems Engineering 2008
- 关键词：Cell growth - Concentration (process) - Plants (botany)
- A New Nitrilase-Producing Strain Named Rhodobacter sphaeroides LHS-305: Biocatalytic Characterization and Substrate Specificity被引量：13收藏
- 作者：Yang, Chunsheng Wang, Xuedong Wei, Dongzhi
- 机构：E China Univ Sci & Technol
- 来源：APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY 2011
- 关键词：Rhodobacter sphaeroides Nitrilase 3-Cyanopyidine Nicotinic acid Biocatalyst
- Enhancing production and purity of 9-OH-AD from phytosterols by balancing metabolic flux of the side-chain degradation and 9-position hydroxylation in Mycobacterium neoaurum被引量：12收藏
- 作者：Zhu, Xiaomei Wang, Xiao Zhang, Jian Wang, Xuedong
- 机构：East China Univ Sci & Technol
- 来源：BIOTECHNOLOGY JOURNAL 2024
- 关键词：9 alpha-hydroxyandrost-4-ene-3,17-dione Hsd4A KshA1 metabolic engineering phytosterols biotransformation
- Two-Step Bioprocess for Reducing Nucleus degradation in Phytosterol Bioconversion by Mycobacterium neoaurum NwIB-R10hsd4A被引量：12收藏
- 作者：Wang, Xuedong Hua, Chaolong Xu, Xinwei Wei, Dongzhi
- 机构：East China Univ Sci & Technol
- 来源：APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY 2019
- 关键词：3-Ketosteroid-(1)-dehydrogenase Mycobacterium neoaurum Nucleus degradation Two-step bioprocess 4-Androstene-3 17-dione
- development of a large scale process for the conversion of polysialogangliosides to monosialotetrahexosylganglioside with a novel strain of Brevibacterium casEI producing sialidase被引量：9收藏
- 作者：Peng, Yan-Feng Wang, Xue-Dong Wei, Dong-Zhi
- 机构： State Key Laboratory of Bioreactor Engineering
- 来源：Biotechnology Letters 2007
- 关键词：Bacteria - Bioconversion - Biotechnology - Brain - Cell culture - Enzymes
- Enhancement of riboflavin production in Bacillus subtilis via in vitro and in vivo metabolic engineering of pentose phosphate pathway被引量：8收藏
- 作者：Zhang, Mengxue Zhao, Xingcong Chen, Xi Li, Mingyue Wang, Xuedong
- 机构：East China Univ Sci & Technol;Univ Calif Davis
- 来源：BIOTECHNOLOGY LETTERS 2021
- 关键词：Bacillus subtilis Carbon metabolism flux Pentose phosphate pathway Riboflavin Sodium gluconate
- Bioprospecting metagenomics of a microbial community on cotton degradation: Mining for new glycoside hydrolases被引量：8收藏
- 作者：Zhang, Guoxiu Liu, Pei Zhang, Lei Wei, Wei Wang, Xuedong Wei, Dongzhi Wang, Wei
- 机构：East China Univ Sci & Technol
- 来源：JOURNAL OF BIOTECHNOLOGY 2016
- 关键词：Glycoside hydrolase Microbial community Metagenomics Crude cotton Expression
- Identification and in situ removal of an inhibitory intermediate to develop an efficient phytosterol bioconversion process using a cyclodextrin-resting cell system被引量：7收藏
- 作者：Wang, Da Zhang, Jian Cao, Dan-Dan Wang, Xuedong Wei, Dongzhi
- 机构：East China Univ Sci & Technol
- 来源：RSC ADVANCES 2021
- 关键词：Cyclodextrins - Metabolites - Production efficiency - Metabolism - Alcohols - Bioconversion
- A recycled batch biotransformation strategy for 22-hydroxy-23,24-bisnorchol-4-ene-3-one production from high concentration of phytosterols by mycobacterial resting cells被引量：7收藏
- 作者：Hu, Yu Wang, Da Wang, Xuedong Wei, Dongzhi
- 机构：East China Univ Sci & Technol
- 来源：BIOTECHNOLOGY LETTERS 2020
- 关键词：Mycobacterium neoaurum Phytosterols Recycled batch biotransformation Hydroxypropyl-beta-cyclodextrin 22-Hydroxy-23 24-bisnorchol-4-ene-3-one
- Nitrate Metabolism decreases the Steroidal Alcohol Byproduct Compared with Ammonium in Biotransformation of Phytosterol to Androstenedione by Mycobacterium neoaurum被引量：7收藏
- 作者：Wang, Xuedong Chen, Rui Wu, Yuyang Wang, Da Wei, Dongzhi
- 机构：East China Univ Sci & Technol
- 来源：APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY 2020
- 关键词：Bioconversion Metabolic redistribution Nitrate Phytosterol Redox level
- Structure-based substrate screening for an enzyme被引量：6收藏
- 作者：Xu, Tao Zhang, Lujia Wang, Xuedong Wei, Dongzhi Li, Tianbi
- 机构：E China Univ Sci & Technol;Rothamsted Res
- 来源：BMC BIOINFORMATICS 2009
- 关键词：Atoms - Carbonyl compounds - Oxygen - Enzymes
- Efficient conversion from polysialogangliosides to monosialotetrahexosylganglioside using Oerskovia xanthineolytica YZ-2被引量：5收藏
- 作者：Zhang, Jianguo Cao, Dan Shen, Danhong Wang, Xuedong Wei, Dongzhi
- 机构：E China Univ Sci & Technol
- 来源：BIOPROCESS AND BIOSYSTEMS ENGINEERING 2011
- 关键词：Monosialotetrahexosylganglioside Sialidase Oerskovia xanthineolytica Fermentation
- The Inhibitory Effect of Cyclodextrin on Oxygen Bioavailability Is a Key Factor for the Metabolic Flux Redistribution Toward Steroid Alcohols in Phytosterol Resting Cells Bioconversion被引量：4收藏
- 作者：Wang, Xue-Dong Chen, Kuan Cao, Dan-Dan Wei, Dong-Zhi
- 机构：East China Univ Sci & Technol
- 来源：APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY 2021
- 关键词：Hydroxypropyl-β -cyclodextrin Mycobacterium Oxygen bioavailability Steroid alcohol Redox balance
