成果/Result
- Improved osteogenesis and angiogenesis of magnesium-doped calcium phosphate cement via macrophage immunomodulation被引量：160收藏
- 作者：Wang, Meng Yu, Yuanman Dai, Kai Ma, Zhengyu Liu, Yang Wang, Jing Liu, Changsheng
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：BIOMATERIALS SCIENCE 2016
- 关键词：Bone - Repair - Immune system - Tissue regeneration - Calcium phosphate - Magnesium compounds - Cements
- Sulfated chitosan rescues dysfunctional macrophages and accelerates wound healing in diabetic mice被引量：119收藏
- 作者：Shen, Tong Dai, Kai Yu, Yuanman Wang, Jing Liu, Changsheng
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：ACTA BIOMATERIALIA 2020
- 关键词：Inflammation Macrophages Transdifferentiation Wound healing Sulfated chitosan
- Biomaterial design for regenerating aged bone: materiobiological advances and paradigmatic shifts被引量：51收藏
- 作者：Dai, Kai Geng, Zhen Zhang, Wenchao Wei, Xue Wang, Jing Nie, Guangjun Liu, Changsheng
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;Shanghai Univ
- 来源：NATIONAL SCIENCE REVIEW 2024
- 关键词：materiobiology biomaterial design aging bone regeneration artificial intelligence
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- Construction of developmentally inspired periosteum-like tissue for bone regeneration被引量：43收藏
- 作者：Dai, Kai Deng, Shunshu Yu, Yuanman Zhu, Fuwei Wang, Jing Liu, Changsheng
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：BONE RESEARCH 2022
- A BMP-2-triggered in vivo osteo-organoid for cell therapy被引量：38收藏
- 作者：Dai, Kai Zhang, Qinghao Deng, Shunshu Yu, Yuanman Zhu, Fuwei Zhang, Shuang Pan, YuanZhong Long, Dandan Wang, Jing Liu, Changsheng
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：SCIENCE ADVANCES 2023
- 关键词：Bone - Cell culture - Flowcharting - Mammals - Proteins - Scaffolds (biology)
- Accelerated Bone Regenerative Efficiency by Regulating Sequential Release of BMP-2 and VEGF and Synergism with Sulfated Chitosan被引量：35收藏
- 作者：Zhang, Shuang Chen, Jie Yu, Yuanman Dai, Kai Wang, Jing Liu, Changsheng
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：ACS BIOMATERIALS SCIENCE & ENGINEERING 2019
- 关键词：BMP-2 VEGF sulfated chitosan spatiotemporal delivery osteogenesis angiogenesis
- Effect of sulfated chitosan hydrogel on vascularization and osteogenesis被引量：32收藏
- 作者：Jiang, Ming Pan, Yuanzhong Liu, Yuanda Dai, Kai Zhang, Qinghao Wang, Jing
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：CARBOHYDRATE POLYMERS 2022
- 关键词：Sulfated chitosan Mesenchymal stem cells Bone regeneration Vascularization
- Enhancement of BMP-2-mediated angiogenesis and osteogenesis by 2-N,6-O-sulfated chitosan in bone regeneration被引量：32收藏
- 作者：Pan, Yuanzhong Chen, Jie Yu, Yuanman Dai, Kai Wang, Jing Liu, Changsheng
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：BIOMATERIALS SCIENCE 2018
- 关键词：Biosynthesis - Bone - Proteins - Sulfur compounds
- Generation of rhBMP-2-induced juvenile ossicles in aged mice被引量：29收藏
- 作者：Dai, Kai Shen, Tong Yu, Yuanman Deng, Shunshu Mao, Lijie Wang, Jing Liu, Changsheng
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：BIOMATERIALS 2020
- 关键词：Aging Bone regeneration rhBMP-2 Mesenchymal stromal cells Type H vessels
- Engineering Neutrophil Immunomodulatory Hydrogels Promoted Angiogenesis被引量：15收藏
- 作者：Gao, Zehua Yu, Yuanman Dai, Kai Zhang, Tingting Ji, Luli Wang, Xuanlin Wang, Jing Liu, Changsheng
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：ACS APPLIED MATERIALS & INTERFACES 2022
- 关键词：options. hydrogels neutrophils inflammation anastomosis angiogenesis
- Sulfated Polysaccharide Regulates the Homing of HSPCs in a BMP-2-Triggered In Vivo Osteo-Organoid被引量：11收藏
- 作者：Dai, Kai Zhang, Wenchao Deng, Shunshu Wang, Jing Liu, Changsheng
- 机构：East China Univ Sci & Technol
- 来源：ADVANCED SCIENCE 2023
- 关键词：hematopoietic stem cell transplantation hematopoietic stem progenitor cells homing in vivo osteo-organoid sulfated polysaccharide
- Self-assembly of dual drug-delivery coating for synergistic bone regeneration被引量：11收藏
- 作者：Qu, Xue He, Fan Tan, Haoqi Yu, Yuanman Axrap, Akbar Wang, Meng Dai, Kai Zhang, Zheng Yang, Fei Wang, Shenguo Kohn, Joachim Liu, Changsheng
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol;Xinjiang Med Univ;Rutgers State Univ;Rutgers State Univ
- 来源：JOURNAL OF MATERIALS CHEMISTRY B 2016
- 关键词：Composite coatings - Targeted drug delivery - Controlled drug delivery - Self assembly - Nanoparticles - Recombinant proteins - Cytology - Bone
- Synergistic osteogenesis and angiogenesis in promoting bone repair by levistolide A-induced smad pathway activation被引量：7收藏
- 作者：Han, Zhengzhe Li, Ang Yu, Yuanman Dai, Kai Yin, Wenjing Li, Xiaolin Wang, Jing Yu, Min Qi, Xin Li, Qi
- 机构：Shanghai Jiao Tong Univ;East China Univ Sci & Technol;Shanghai Univ Tradit Chinese Med
- 来源：COMPOSITES PART B-ENGINEERING 2024
- 关键词：Bone defects Levistolide a Osteogenesis Angiogenesis
- Injured bone-triggered osteokines secretion promotes diabetic wound healing被引量：4收藏
- 作者：Shen, Tong Dai, Kai Zhang, Shuang Wang, Jing Liu, Changsheng
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：BONE RESEARCH 2025
- Sulfated polysaccharide facilitates macrophage-Treg crosstalk to mitigate chronic inflammation in diabetic wound healing被引量：4收藏
- 作者：Shen, Tong Xu, Hao Dai, Kai Wang, Jing Liu, Changsheng
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：BIOACTIVE MATERIALS 2026
- 关键词：Diabetic wound healing Regulatory T cells Immune Microneedles Macrophages
- Biomaterial-assisted therapeutic cell production and modi fi cation in vivo被引量：3收藏
- 作者：Dai, Kai Wang, Jing Liu, Changsheng
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：EXPERIMENTAL HEMATOLOGY 2024
- Amphiphilic cytokine traps remodel marrow adipose tissue for hematopoietic microenvironment amelioration被引量：2收藏
- 作者：Deng, Shunshu Zhang, Shuang Shen, Tong Wang, Xuanlin Gao, Zehua Zhang, Wenchao Dai, Kai Wang, Jing Liu, Changsheng
- 机构：East China Univ Sci & Technol;Tongji Univ;East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：BIOACTIVE MATERIALS 2024
- 关键词：Adipocytes Hematopoiesis In vivo osteo-organoids Stem cell factor Sulfated chitosan Tissue regeneration
- In Vivo Osteo-organoid Approach for Harvesting Therapeutic Hematopoietic Stem/Progenitor Cells被引量：2收藏
- 作者：Zhang, Wenchao Wei, Xue Wang, Qingliang Dai, Kai Wang, Jing Liu, Changsheng
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：JOVE-JOURNAL OF VISUALIZED EXPERIMENTS 2024
- Development-based In Vivo Bioreactor Strategy for Challenging Senescent Bone Reconstruction被引量：0收藏
- 作者：Zhang, Wenchao Dai, Kai Shen, Tong Gao, Zehua Yan, Fengying Feng, Yuke Wang, Xuanlin Zhang, Shaozhen Wang, Jing Liu, Changsheng
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：ADVANCED SCIENCE 2026
- 关键词：in vivo bioreactor developmental engineering segmental bone defect aging
- Sulfated polysaccharide prevents senescent adipocyte-driven osteonecrosis by stem cell fate reprogramming被引量：0收藏
- 作者：Zhang, Shuang Deng, Shunshu Dai, Kai Liu, Yang Wang, Jing Liu, Changsheng
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;Fudan Univ
- 来源：BIOACTIVE MATERIALS 2026
- 关键词：Osteonecrosis Sulfated polysaccharide Aging Adipocyte Glucocorticoid
- Materiobiology-guided regulation of mesenchymal stromal cell fate for aging-related diseases: From basic parameter design to clinical application被引量：0收藏
- 作者：Feng, Yuke Qiu, Yuqian Zhang, Shaozhen Dai, Kai Wang, Jing Liu, Changsheng
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：BIOACTIVE MATERIALS 2026
- 关键词：Mesenchymal stromal cell Materiobiology Cell fate regulation Biomaterial design Anti-aging
