成果/Result
- Influence of High Solid Concentration on Enzymatic Hydrolysis and Fermentation of Steam-Exploded Corn Stover Biomass被引量：148收藏
- 作者：Lu, Yifeng Wang, Yonghong Xu, Guoqian Chu, Ju Zhuang, Yingping Zhang, Siliang
- 机构：E China Univ Sci & Technol
- 来源：APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY 2010
- 关键词：Bioethanol Corn stover High solid concentration Enzymatic hydrolysis Fermentation
- Harnessing the intracellular triacylglycerols for titer improvement of polyketides in Streptomyces被引量：143收藏
- 作者：Wang, Weishan Li, Shanshan Li, Zilong Zhang, Jingyu Fan, Keqiang Tan, Gaoyi Ai, Guomin Lam, Sin Man Shui, Guanghou Yang, Zhiheng Lu, Hongzhong Jin, Pinjiao Li, Yihong Chen, Xiangyin Xia, Xuekui Liu, Xueting Dannelly, H. Kathleen Yang, Chen Yang, Yi Zhang, Siliang Alterovitz, Gil Xiang, Wensheng Zhang, Lixin
- 机构：Chinese Acad Sci;East China Univ Sci & Technol;Chinese Acad Agr Sci;Chinese Acad Sci;Qilu Univ Technol
- 来源：NATURE BIOTECHNOLOGY 2020
- 关键词：Ketones - Metabolism - Biochemistry - Bacteria - Metabolites - Glycerol
- GAP Promoter Library for Fine-Tuning of Gene Expression in Pichia pastoris被引量：113收藏
- 作者：Qin, Xiulin Qian, Jiangchao Yao, Gaofeng Zhuang, Yingping Zhang, Siliang Chu, Ju
- 机构：E China Univ Sci & Technol
- 来源：APPLIED AND ENVIRONMENTAL MICROBIOLOGY 2011
- Optimization of cellulase mixture for efficient hydrolysis of steam-exploded corn stover by statistically designed experiments被引量：112收藏
- 作者：Zhou, Jin Wang, Yong-Hong Chu, Ju Luo, Ling-Zhi Zhuang, Ying-Ping Zhang, Si-Liang
- 机构：E China Univ Sci & Technol
- 来源：BIORESOURCE TECHNOLOGY 2009
- 关键词：Cellulase mixture Optimization Steam-exploded corn stover Statistically designed experiments Bioethanol
- Identification and purification of the main components of cellulases from a mutant strain of Trichoderma viride T 100-14被引量：94收藏
- 作者：Zhou, Jin Wang, Yong-Hong Chu, Ju Zhuang, Ying-Ping Zhang, Si-Liang Yin, Peng
- 机构：E China Univ Sci & Technol
- 来源：BIORESOURCE TECHNOLOGY 2008
- 关键词：Trichoderma viride T 100-14 mutant strain cellulase identification purification
- Reverse biological engineering of hrdB to enhance the production of avermectins in an industrial strain of Streptomyces avermitilis被引量：80收藏
- 作者：Zhuo, Ying Zhang, Wenquan Chen, Difei Gao, Hong Tao, Jun Liu, Mei Gou, Zhongxuan Zhou, Xianlong Ye, Bang-Ce Zhang, Qing Zhang, Siliang Zhang, Li-Xin
- 机构：Chinese Acad Sci;E China Univ Sci & Technol;Hebei Veyong Biochem Co Ltd;Chinese Acad Sci
- 来源：PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 2010
- 关键词：precision engineering RNA polymerase overproduction
- Feature-matching Pattern-based Support Vector Machines for Robust Peptide Mass Fingerprinting被引量：79收藏
- 作者：Li, Youyuan Hao, Pei Zhang, Siliang Li, Yixue
- 机构：E China Univ Sci & Technol;Shanghai Ctr Bioinformat Technol
- 来源：MOLECULAR & CELLULAR PROTEOMICS 2011
- Multiple Propionyl Coenzyme A-Supplying Pathways for Production of the Bioplastic Poly(3-Hydroxybutyrate-co-3-Hydroxyvalerate) in Haloferax mediterranei被引量：76收藏
- 作者：Han, Jing Hou, Jing Zhang, Fan Ai, Guomin Li, Ming Cai, Shuangfeng Liu, Hailong Wang, Lei Wang, Zejian Zhang, Siliang Cai, Lei Zhao, Dahe Zhou, Jian Xiang, Hua
- 机构：Chinese Acad Sci;Univ Chinese Acad Sci;Chinese Acad Sci;E China Univ Sci & Technol
- 来源：APPLIED AND ENVIRONMENTAL MICROBIOLOGY 2013
- Improved vitamin B12 production by step-wise reduction of oxygen uptake rate under dissolved oxygen limiting level during fermentation process被引量：74收藏
- 作者：Wang, Ze-Jian Wang, Hui-Yuan Li, Yong-Liang Chu, Ju Huang, Ming-Zhi Zhuang, Ying-Ping Zhang, Si-Liang
- 机构：E China Univ Sci & Technol;Grp Hua Rong Pharmaceut Co Ltd
- 来源：BIORESOURCE TECHNOLOGY 2010
- 关键词：Vitamin B-12 Oxygen uptake rate Pseudomonas denitrificans Scale-up Oxygen supply strategy
- Development of a continuous cell-recycle fermentation system for production of lactic acid by Lactobacillus paracasei被引量：65收藏
- 作者：Xu, Guo-qian Chu, Ju Wang, Yong-hong Zhuang, Ying-ping Zhang, Si-liang Peng, Hua-qiong
- 机构：E China Univ Sci & Technol
- 来源：PROCESS BIOCHEMISTRY 2006
- 关键词：electromagnetic flow-meter Lactobacillus paracasei lactic acid tangential velocity membrane bioreactor cell-recycle
- Oxygen uptake rate optimization with nitrogen regulation for erythromycin production and scale-up from 50 L to 372 m3 scale被引量：64收藏
- 作者：Zou, Xiang Hang, Hai-feng Chu, Ju Zhuang, Ying-ping Zhang, Si-liang
- 机构：E China Univ Sci & Technol;Southwest Univ
- 来源：BIORESOURCE TECHNOLOGY 2009
- 关键词：Erythromycin Industrial scale Metabolic flux Oxygen uptake rate Scale-up
- Enhancement of phototrophic hydrogen production by Rhodobacter sphaeroides ZX-5 using a novel strategy - shaking and extra-light supplementation approach被引量：62收藏
- 作者：Li, Xu Wang, Yong-Hong Zhang, Si-Liang Chu, Ju Zhang, Ming Huang, Ming-Zhi Zhuang, Ying-Ping
- 机构：E China Univ Sci & Technol
- 来源：INTERNATIONAL JOURNAL OF HYDROGEN ENERGY 2009
- 关键词：Photo-hydrogen production Rhodobacter sphaeroides Light intensity Hydrogen production rate Light attenuation kinetics
- Fluid dynamics investigation of variant impeller combinations by simulation and fermentation experiment被引量：61收藏
- 作者：Xia, Jian-Ye Wang, Yong-Hong Zhang, Si-Liang Chen, Ning Yin, Peng Zhuang, Ying-Ping Chu, Ju
- 机构：E China Univ Chem Technol
- 来源：BIOCHEMICAL ENGINEERING JOURNAL 2009
- 关键词：Dissolved oxygen Fluid mechanics Gas-liquid mass transfer Mixing Mycelia fermentation Shear environment
- Flow Pattern, Mixing, Gas Hold-Up and Mass Transfer Coefficient of Triple-Impeller Configurations in Stirred Tank Bioreactors被引量：60收藏
- 作者：Xie, Minghui Xia, Jianye Zhou, Zhen Chu, Ju Zhuang, Yingping Zhang, Siliang
- 机构：E China Univ Sci & Technol
- 来源：INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH 2014
- 关键词：Gases - Liquids - Mixing - Pumps - Turbine components - Flow patterns - Mass transfer - Turbomachine blades - Velocity
- Genetic modulation of the overexpression of tailoring genes eryK and eryG leading to the improvement of erythromycin a purity and production in Saccharopolyspora erythraea fermentation被引量：60收藏
- 作者：Chen, Yun Deng, Wei Wu, Jiequn Qian, Jiangchao Chu, Ju Zhuang, Yingping Zhang, Siliang Liu, Wen
- 机构：E China Univ Sci & Technol;Chinese Acad Sci
- 来源：APPLIED AND ENVIRONMENTAL MICROBIOLOGY 2008
- Progress in the research of S-adenosyl-L-methionine production被引量：59收藏
- 作者：Chu, Ju Qian, Jiangchao Zhuang, Yingping Zhang, Siliang Li, Yourong
- 机构：E China Univ Sci & Technol
- 来源：APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 2013
- 关键词：S-adenosyl-L-methionine L-Methionine ATP L-Methionine adenosyltransferase Pichia pastoris
- Screening endogenous signal peptides and protein folding factors to promote the secretory expression of heterologous proteins in Pichia pastoris被引量：59收藏
- 作者：Duan, Guangdong Ding, Lumei Wei, Dongsheng Zhou, Hangcheng Chu, Ju Zhang, Siliang Qian, Jiangchao
- 机构：East China Univ Sci & Technol
- 来源：JOURNAL OF BIOTECHNOLOGY 2019
- 关键词：Signal peptides Folding factors Pichia pastoris Heterologous protein Secretory expression
- CFD analysis of the turbulent flow in baffled shake flasks被引量：49收藏
- 作者：Li, Chao Xia, Jian-Ye Chu, Ju Wang, Yong-Hong Zhuang, Ying-Ping Zhang, Si-Liang
- 机构：E China Univ Sci & Technol
- 来源：BIOCHEMICAL ENGINEERING JOURNAL 2013
- 关键词：Shake flask Hydrodynamics Mass transfer Mixing Shear force Power consumption
- Application of Euler-Lagrange CFD for quantitative evaluating the effect of shear force on Carthamus tinctorius L. cell in a stirred tank bioreactor被引量：49收藏
- 作者：Liu, Yu Wang, Ze-Jian Xia, Jian-Ye Haringa, Cees Liu, Ya-Ping Chu, Ju Zhuang, Ying-Ping Zhang, Si-Liang
- 机构：East China Univ Sci & Technol;Dalian Pract Biotechnol Co Ltd;Delft Univ Technol
- 来源：BIOCHEMICAL ENGINEERING JOURNAL 2016
- 关键词：Plant cell culture Fluid mechanics Agitation Power consumption C tinctorius L. cell Stress thresholds
- Power consumption, local and average volumetric mass transfer coefficient in multiple-impeller stirred bioreactors for xanthan gum solutions被引量：48收藏
- 作者：Xie, Ming-hui Xia, Jian-ye Zhou, Zhen Zhou, Guo-zhong Chu, Ju Zhuang, Ying-ping Zhang, Si-liang Noorman, Henk
- 机构：E China Univ Sci & Technol;Wenzhou Great Wall Mixer Design Inst;DSM Biotechnol Ctr
- 来源：CHEMICAL ENGINEERING SCIENCE 2014
- 关键词：Power Mass transfer Xanthan gum Non-Newtonian fluid Impeller combination
- Understanding the effect of foreign gene dosage on the physiology of Pichia pastoris by transcriptional analysis of key genes被引量：47收藏
- 作者：Zhu, Taicheng Guo, Meijin Zhuang, Yingping Chu, Ju Zhang, Siliang
- 机构：E China Univ Sci & Technol;Chinese Acad Sci
- 来源：APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 2011
- 关键词：Gene dosage Pichia pastoris Methanol metabolism Cell physiology mRNA quantitative analysis
- Effects of light/dark cycle, mixing pattern and partial pressure of H2 on biohydrogen production by Rhodobacter sphaeroides ZX-5被引量：47收藏
- 作者：Li, Xu Wang, Yonghong Zhang, Siliang Chu, Ju Zhang, Ming Huang, Mingzhi Zhuang, Yingping
- 机构：E China Univ Sci & Technol
- 来源：BIORESOURCE TECHNOLOGY 2011
- 关键词：Photo-hydrogen production Rhodobacter sphaeroides Light/dark cycle Shaking velocity Hydrogen partial pressure
- Improved large-scale production of vitamin B12 by Pseudomonas denitrificans with betaine feeding被引量：45收藏
- 作者：Li, Kun-Tai Liu, Dong-Hong Li, Yong-Liang Chu, Ju Wang, Yong-Hong Zhuang, Ying-Ping Zhang, Si-Liang
- 机构：E China Univ Sci & Technol;Jiangxi Agr Univ;Grp Hua Rong Pharmaceut Co Ltd
- 来源：BIORESOURCE TECHNOLOGY 2008
- 关键词：betaine large-scale production vitamin B-12 Pseudomonas denitrificans
- Intracellular expression of VitreoSCIlla hemoglobin improves S-adenosylmethionine production in a recombinant Pichia pastoris被引量：44收藏
- 作者：Chen, Huaxin Chu, Ju Zhang, Siliang Zhuang, Yingping Qian, Jiangchao Wang, Yonghong Hu, Xiaoqing
- 机构：E China Univ Sci & Technol
- 来源：APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 2007
- 关键词：S-adenosylmethionine VitreoSCIlla hemoglobin Pichia pastoris methionine adenosyltransferase
- Effect of glycosylation on biochemical characterization of recombinant phytase expressed in Pichia pastoris被引量：44收藏
- 作者：Guo, Meijin Hang, Haifeng Zhu, Taicheng Zhuang, Yingping Chu, Ju Zhang, Siliang
- 机构：E China Univ Sci & Technol;Jiangxi Agr Univ
- 来源：ENZYME AND MICROBIAL TECHNOLOGY 2008
- 关键词：phytase glycosylation biochemical characterization thermostability micro-heterogeneity
- An effective and simplified pH-stat control strategy for the industrial fermentation of vitamin B12 by Pseudomonas denitrificans被引量：43收藏
- 作者：Li, Kun-Tai Liu, Dong-Hong Chu, Ju Wang, Yong-Hong Zhuang, Ying-Ping Zhang, Si-Liang
- 机构：E China Univ Sci & Technol
- 来源：BIOPROCESS AND BIOSYSTEMS ENGINEERING 2008
- 关键词：pH-stat Pseudomonas denitrificans vitamin B12
- Molecular cloning and characterization of two novel cellulase genes from the mollusc Ampullaria crossean被引量：42收藏
- 作者：Guo, Rui Ding, Ming Zhang, Si-Liang Xu, Gen-Jun Zhao, Fu-Kun
- 机构：E China Univ Sci & Technol;Chinese Acad Sci;Zhejiang Sci Tech Univ
- 来源：JOURNAL OF COMPARATIVE PHYSIOLOGY B-BIOCHEMICAL SYSTEMS AND ENVIRONMENTAL PHYSIOLOGY 2008
- 关键词：cellulase endoglucanase EG27 Ampullaria crossean gene cloning
- A systematical investigation on the genetic stability of multi-copy Pichia pastoris strains被引量：41收藏
- 作者：Zhu, Taicheng Guo, Meijin Sun, Chen Qian, Jiangchao Zhuang, Yingping Chu, Ju Zhang, Siliang
- 机构：E China Univ Sci & Technol;Jiangxi Agr Univ
- 来源：BIOTECHNOLOGY LETTERS 2009
- 关键词：Copy number Genetic stability Multi-copy Pichia pastoris Porcine insulin precursor
- Systems perspectives on erythromycin biosynthesis by comparative genomic and transcriptomic analyses of S-erythraea E3 and NRRL23338 strains被引量：40收藏
- 作者：Li, Yuan-Yuan Chang, Xiao Yu, Wen-Bang Li, Hao Ye, Zhi-Qiang Yu, Hui Liu, Bao-Hong Zhang, Yan Zhang, Si-Liang Ye, Bang-Ce Li, Yi-Xue
- 机构：Shanghai Ctr Bioinformat Technol;E China Univ Sci & Technol;Chinese Acad Sci;Peking Univ;Childrens Hosp Philadelphia
- 来源：BMC GENOMICS 2013
- 关键词：S. erythraea Erythromycin biosynthesis Functional comparative genetics Regulation mechanism
- Optimization of l-methionine feeding strategy for improving S-adenosyl-l-methionine production by methionine adenosyltransferase overexpressed Pichia pastoris被引量：39收藏
- 作者：Hu, Hui Qian, Jiangchao Chu, Ju Wang, Yonghong Zhuang, Yingping Zhang, Siliang
- 机构：E China Univ Sci & Technol
- 来源：APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 2009
- 关键词：S-adenosyl-L-methionine Methionine adenosyltransferase L-methionine Pichia pastoris ATP
