成果/Result
- Antioxidant properties of a vegetable-fruit beverage fermented with two Lactobacillus plantarum strains被引量：85收藏
- 作者：Yang, Xiaoxing Zhou, Jiachun Fan, Liqiang Qin, Zhen Chen, Qiming Zhao, Liming
- 机构：East China Univ Sci & Technol;SCICBT
- 来源：FOOD SCIENCE AND BIOTECHNOLOGY 2018
- 关键词：Lactobacillus plantarum Vegetable-fruit beverage Fermentation Metabolites Antioxidant activities
- Progress in the biosynthesis of bio-based PET and PEF polyester monomers被引量：76收藏
- 作者：Cui, Yanan Deng, Chen Fan, Liqiang Qiu, Yongjun Zhao, Liming
- 机构：East China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol SCI
- 来源：GREEN CHEMISTRY 2023
- 关键词：Biochemistry - Biomass - Biosynthesis - Conservation - Cost effectiveness - Enzymes - Ethylene - Monomers - Natural resources - Petroleum industry - Plastic bottles - Polyethylene terephthalates
- Chitooligosaccharides display anti-tumor effects against human cervical cancer cells via the apoptotic and autophagic pathways被引量：57收藏
- 作者：Zhao, Mengyao Gu, Liming Li, Yun Chen, Shumin You, Jiangshan Fan, Liqiang Wang, Yudong Zhao, Liming
- 机构：East China Univ Sci & Technol;Shanghai Jiao Tong Univ;SCICBT
- 来源：CARBOHYDRATE POLYMERS 2019
- 关键词：Chitooligosaccharides Enzyme-membrane coupling reactor Apoptosis ROS production Autophagy
- Insights into the nanofiltration separation mechanism of monosaccharides by molecular dynamics simulation被引量：49收藏
- 作者：Yao, Lei Qin, Zhen Chen, Qiming Zhao, Mengyao Zhao, Hefei Ahmad, Waheed Fan, Liqiang Zhao, Liming
- 机构：East China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol SC;Univ Nebraska
- 来源：SEPARATION AND PURIFICATION TECHNOLOGY 2018
- 关键词：Monosaccharide Nanofiltration Molecular dynamics simulation Diffusion coefficient Interaction energy
- High level production of a Bacillus amlyoliquefaciens chitosanase in Pichia pastoris suitable for chitooligosaccharides preparation被引量：41收藏
- 作者：Luo, Sa Qin, Zhen Chen, Qiming Fan, Liqiang Jiang, Lihua Zhao, Liming
- 机构：East China Univ Sci & Technol;SCICBT
- 来源：INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES 2020
- 关键词：Chitosanase Chitooligosaccharides Glycoside hydmlase family 46
- Regioselectivity Engineering of Epoxide Hydrolase: Near-Perfect Enantioconvergence through a Single Site Mutation被引量：41收藏
- 作者：Li, Fu-Long Kong, Xu-Dong Chen, Qi Zheng, Yu-Cong Xu, Qin Chen, Fei-Fei Fan, Li-Qiang Lin, Guo-Qiang Zhou, Jiahai Yu, Hui-Lei Xu, Jian-He
- 机构：East China Univ Sci & Technol;Chinese Acad Sci;Shanghai Jiao Tong Univ;Shanghai Jiao Tong Univ
- 来源：ACS CATALYSIS 2018
- 关键词：biocatalysis epoxide hydrolase crystal structure regioselectivity enantioconvergence protein engineering
- The involvement of oxidative stress, neuronal lesions, neurotransmission impairment, and neuroinflammation in acrylamide-induced neurotoxicity in C57/BL6 mice被引量：33收藏
- 作者：Zhao, Mengyao Deng, Linlin Lu, Xiaoxuan Fan, Liqiang Zhu, Yang Zhao, Liming
- 机构：East China Univ Sci & Technol;Wageningen Univ & Res
- 来源：ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH 2022
- 关键词：acrylamide Oxidative stress Neurotoxicity Neurotransmission impairment Neuroinflammation NLRP3 inflammasome
- Efficient Immobilization of Bacterial GH Family 46 Chitosanase by Carbohydrate-Binding Module Fusion for the Controllable Preparation of Chitooligosaccharides被引量：33收藏
- 作者：Lin, Si Qin, Zhen Chen, Qiming Fan, Liqiang Zhou, Jiachun Zhao, Liming
- 机构：East China Univ Sci & Technol;SCICBT
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2019
- 关键词：chitosanase carbohydrate binding module chitooligosaccharide one-step immobilization-purification packed-bed reactor
- Expression and Characterization of a Novel Lipase from Aspergillus fumigatus with High Specific activity被引量：31收藏
- 作者：Shangguan, Jiao-Jiao Liu, Yu-Qiang Wang, Fu-Jun Zhao, Jian Fan, Li-Qiang Li, Su-Xia Xu, Jian-He
- 机构：E China Univ Sci & Technol;Shanghai Univ Chinese Tradit Med
- 来源：APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY 2011
- 关键词：Aspergillus fumigatus Recombinant lipase Expression Characterization active site
- Increasing thermal stability of glutamate decarboxylase from Escherichia. coli by site-directed saturation mutagenesis and its application in GABA production被引量：30收藏
- 作者：Fan, Li-Qiang Li, Ming-Wei Qiu, Yong-jun Chen, Qi-ming Jiang, Si-Jing Shang, Yu-Jie Zhao, Li-Ming
- 机构：East China Univ Sci & Technol;SCICBT
- 来源：JOURNAL OF BIOTECHNOLOGY 2018
- 关键词：Glutamate decarboxylase gamma-Aminobutyrate Site-directed saturation mutagenesis Thermostability Hydrogen bonds
- Heterologous overexpression of Vigna radiata epoxide hydrolase in Escherichia coli and its catalytic performance in enantioconvergent hydrolysis of p-nitrostyrene oxide into (R)-p-nitrophenyl glycol被引量：29收藏
- 作者：Zhu, Qing-Qing He, Wan-Hong Kong, Xu-Dong Fan, Li-Qiang Zhao, Jian Li, Su-Xia Xu, Jian-He
- 机构：E China Univ Sci & Technol
- 来源：APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 2014
- 关键词：RT-PCR Vigna radiata epoxide hydrolase p-Nitrostyrene oxide Enantioconvergency Characterization
- Chitobiose alleviates oleic acid-induced lipid accumulation by decreasing fatty acid uptake and triglyceride synthesis in HepG2 cells被引量：29收藏
- 作者：Li, Xiaodan Zhao, Mengyao Fan, Liqiang Cao, Xuni Chen, Liehuan Chen, Junhui Lo, Y. Martin Zhao, Liming
- 机构：East China Univ Sci & Technol;Fuzhou Univ;Huizhou Long Dragon Biotechnol Co Ltd;Peking Univ
- 来源：JOURNAL OF FUNCTIONAL FOODS 2018
- 关键词：Chitobiose Hepatic steatosis Oleic acid CD36 DGAT2
- Bioconversion of chitin into chitin oligosaccharides using a novel chitinase with high chitin-binding capacity被引量：26收藏
- 作者：Zhao, Qiong Fan, Liqiang Deng, Chen Ma, Chunyu Zhang, Chunyue Zhao, Liming
- 机构：East China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol SCI;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES 2023
- 关键词：Chitinase Chitin oligosaccharides Purification Molecular simulation Biodegradation
- Chitooligosaccharide plays essential roles in regulating proline metabolism and cold stress tolerance in rice seedlings被引量：22收藏
- 作者：Zhang, Yang Fan, Liqiang Zhao, Mengyao Chen, Qiming Qin, Zhen Feng, Zhihang Fujiwara, Toru Zhao, Liming
- 机构：East China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol SC;Univ Tokyo
- 来源：ACTA PHYSIOLOGIAE PLANTARUM 2019
- 关键词：Chitooligosaccharide Rice seedlings Cold stress Glutamate synthesis Proline metabolism
- Chemoenzymatic enantioconvergent hydrolysis of p-nitrostyrene oxide into (R)-p-nitrophenyl glycol by a newly cloned epoxide hydrolase VrEH2 from Vigna radiata被引量：21收藏
- 作者：Wu, Yan-Wen Kong, Xu-Dong Zhu, Qing-Qing Fan, Li-Qiang Xu, Jian-He
- 机构：E China Univ Sci & Technol
- 来源：CATALYSIS COMMUNICATIONS 2015
- 关键词：Vigna radiata epoxide hydrolase Recombinant expression Enzymatic property Enantioconvergency Chemoenzymatic synthesis (R)-p-nitrophenyl glycol
- Improvement of Ethanol Productivity and Energy Efficiency by Degradation of Inhibitors Using Recombinant Zymomonas mobilis (pHW20a-fdh)被引量：21收藏
- 作者：Dong, Hong-Wei Fan, Li-Qiang Luo, Zichen Zhong, Jian-Jiang Ryu, Dewey D. Y. Bao, Jie
- 机构：E China Univ Sci & Technol;Shanghai Res Inst Chem Ind;Shanghai Jiao Tong Univ;Univ Calif Davis
- 来源：BIOTECHNOLOGY AND BIOENGINEERING 2013
- 关键词：recombinant Z mobilis ZM4 (pHW20a-fdh) formate dehydrogenase (fdh) NADH regeneration growth inhibitor inhibitor degradation corn stover hydrolysate (CSH)
- A novel human derived cell-penetrating peptide in drug delivery被引量：20收藏
- 作者：Zhao, Jian Gao, Peng Xiao, Wei Fan, Li-Qiang Wang, Fu-Jun Li, Su-Xia Liu, Jian-Wen
- 机构：E China Univ Sci & Technol;Zhejiang Reachall Pharmaceut Co Ltd
- 来源：MOLECULAR BIOLOGY REPORTS 2011
- 关键词：hC-SOD3 Human cell-penetrating peptide Apoptin Drug delivery
- Chitooligosaccharides enhance cold tolerance by repairing photodamaged PS II in rice被引量：19收藏
- 作者：Zhou, Jiachun Chen, Qiao Zhang, Yang Fan, Liqiang Qin, Zhen Chen, Qiming Qiu, Yongjun Jiang, Lihua Zhao, Liming
- 机构：East China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol SC
- 来源：JOURNAL OF AGRICULTURAL SCIENCE 2018
- 关键词：Chitooligosaccharides cold tolerance PS II repairing rice stress-responsive gene
- Gene cloning and expression of a novel hypoglycaemic peptide from Momordica charantia被引量：18收藏
- 作者：Wang, Bi-lian Zhang, Wen-ji Zhao, Jian Wang, Fu-jun Fan, Li-qiang Wu, Yi-xin Hu, Zhi-bi
- 机构：E China Univ Sci & Technol;Shanghai Univ Chinese Tradit Med;Hamamatsu Univ Sch Med
- 来源：JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE 2011
- 关键词：Momordica charantia gene cloning polypeptide-P hypoglycaemic effect
- Structure-function analysis of Gynuella sunshinyii chitosanase uncovers the mechanism of substrate binding in GH family 46 members被引量：18收藏
- 作者：Wang, Yani Qin, Zhen Fan, Liqiang Zhao, Liming
- 机构：East China Univ Sci & Technol;Shanghai Univ;Shanghai Collaborat Innovat Ctr Biomfg Technol SC
- 来源：INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES 2020
- 关键词：Chitooligosaccharides Chitosanase Complex structure Substrate recognition GH family 46
- De novo biosynthesis of 2′-fucosyllactose in engineered Pichia pastoris被引量：18收藏
- 作者：Qian, Difan Zhang, Chunyue Deng, Chen Zhou, Mian Fan, Liqiang Zhao, Liming
- 机构：East China Univ Sci & Technol;Shanghai Changzheng Hosp;Shanghai Collaborat Innovat Ctr Biomfg Technol SCI
- 来源：BIOTECHNOLOGY LETTERS 2023
- 关键词：Biosynthesis 2 '-Fucosyllactose Human milk oligosaccharides Pichia pastoris
- A Novel GH Family 20 β-N-acetylhexosaminidase With Both Chitosanase and Chitinase activity From Aspergillus oryzae被引量：17收藏
- 作者：Qu, Tianle Zhang, Chunyue Qin, Zhen Fan, Liqiang Jiang, Lihua Zhao, Liming
- 机构：East China Univ Sci & Technol;Shanghai Univ;Shanghai Collaborat Innovat Ctr Biomfg Technol SC
- 来源：FRONTIERS IN MOLECULAR BIOSCIENCES 2021
- 关键词：beta-N-acetylhexosaminidase aminooligosaccharide glycoside hydrolase family 20 chitosan chitin
- Suppression of GOLM1 by EGCG through HGF/HGFR/AKT/GSK-3β/β-catenin/c-Myc signaling pathway inhibits cell migration of MDA-MB-231被引量：17收藏
- 作者：Xie, Ling Yi, Jun Song, Yongjia Zhao, Mengyao Fan, Liqiang Zhao, Liming
- 机构：East China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol SC
- 来源：FOOD AND CHEMICAL TOXICOLOGY 2021
- 关键词：GOLM1 Epigallocatechin-3-Gallate Migration MDA-MB-231
- An individually coated near-infrared fluorescent protein as a safe and robust nanoprobe for in vivo imaging被引量：16收藏
- 作者：Yang, Yu Xiang, Kun Yang, Yi-Xin Wang, Yan-Wen Zhang, Xin Cui, Yangdong Wang, Haifang Zhu, Qing-Qing Fan, Liqiang Liu, Yuanfang Cao, Aoneng
- 机构：Shanghai Univ;E China Univ Sci & Technol;Peking Univ
- 来源：NANOSCALE 2013
- 关键词：Quantum yield - Probes - Fluorescence imaging - Proteins - Infrared devices - Silica
- Establishment of a nanofiltration rejection sequence and calculated rejections of available monosaccharides被引量：16收藏
- 作者：Liu, Hetian Zhao, Liming Fan, Liqiang Jiang, Lihua Qiu, Yongjun Xia, Quanming Zhou, Jiachun
- 机构：E China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol SC
- 来源：SEPARATION AND PURIFICATION TECHNOLOGY 2016
- 关键词：Nanofiltration Monosaccharide Molecular shape Spectrum of monosaccharide rejection
- Significantly Improved Expression and Biochemical Properties of Recombinant Serratia marcescens Lipase as Robust Biocatalyst for Kinetic Resolution of Chiral Ester被引量：16收藏
- 作者：Wang, Yi Zhao, Jian Xu, Jian-He Fan, Li-Qiang Li, Su-Xia Zhao, Li-Li Mao, Xiao-Bo
- 机构：E China Univ Sci & Technol
- 来源：APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY 2010
- 关键词：Serratia marcescens ECU1010 Lipase Soluble expression Purification Characterization Enantioselectivity Biocatalytic resolution
- Improved breast cancer cell-specific intracellular drug delivery and therapeutic efficacy by coupling decoration with cell penetrating peptide and SP90 peptide被引量：15收藏
- 作者：Fan, Li-Qiang Du, Guo-Xiu Li, Peng-Fei Li, Ming-Wei Sun, Yao Zhao, Li-Ming
- 机构：East China Univ Sci & Technol
- 来源：BIOMEDICINE & PHARMACOTHERAPY 2016
- 关键词：Cell-penetrating peptide Homing peptide Targeted drug delivery Breast cancer therapy VPR
- Enhanced Low Molecular Weight Poly-γ-Glutamic acid Production in Recombinant Bacillus subtilis 1A751 with Zinc Ion被引量：15收藏
- 作者：Jiang, Sijing Fan, Liqiang Zhao, Mengyao Qiu, Yongjun Zhao, Liming
- 机构：East China Univ Sci & Technol;SCICBT
- 来源：APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY 2019
- 关键词：Recombinant Bacillus subtilis Low molecular weight Poly-gamma-glutamic acid (gamma-PGA) Poly-gamma-glutamic acid synthase pgsBCAE center dot Zn2+
- Efficient inhibition of Cronobacter biofilms by chitooligosaccharides of specific molecular weight被引量：14收藏
- 作者：Lu, Jun Chen, Qiming Pan, Bolin Qin, Zhen Fan, Liqiang Xia, Quanming Zhao, Liming
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY 2019
- 关键词：Cronobacter spp Biofilms Chitooligosaccharides
- Facile Synthesis of Enantiopure 4-Substituted 2-Hydroxy-4-butyrolactones using a Robust Fusarium Lactonase被引量：13收藏
- 作者：Chen, Bing Yin, Hai-Feng Wang, Zhen-Sheng Xu, Jian-He Fan, Li-Qiang Zhao, Jian
- 机构：E China Univ Sci & Technol;PepTech Corp Shanghai
- 来源：ADVANCED SYNTHESIS & CATALYSIS 2009
- 关键词：chemo-enzymatic process circular dichroism Fusarium proliferatum lactonase stereoselectivity 4-substituted 2-hydroxy-4-butyrolactones
