成果/Result
- Predicting physical stability of solid dispersions by machine learning techniques被引量：128收藏
- 作者：Han, Run Xiong, Hui Ye, Zhuyifan Yang, Yilong Huang, Tianhe Jing, Qiufang Lu, Jiahong Pan, Hao Ren, Fuzheng Ouyang, Defang
- 机构：Univ Macau;East China Univ Sci & Technol;Liaoning Univ
- 来源：JOURNAL OF CONTROLLED RELEASE 2019
- 关键词：Solid dispersion Physical stability Machine learning Molecular modeling
- A thermo-sensitive PLGA-PEG-PLGA hydrogel for sustained release of docetaxel被引量：93收藏
- 作者：Gao, Yuan Ren, Fuzheng Ding, Baoyue Sun, Ningyun Liu, Xiang Ding, Xueying Gao, Shen
- 机构：Second Mil Med Univ;E China Univ Sci & Technol
- 来源：JOURNAL OF DRUG TARGETING 2011
- 关键词：PLGA-PEG-PLGA docetaxel sustained release intratumoral delivery thermo-sensitive hydrogel
- Characteristics of bicalutamide solid dispersions and improvement of the dissolution被引量：41收藏
- 作者：Ren, Fuzheng Jing, Qiufang Tang, Yanhui Shen, Yongjia Chen, Jialei Gao, Feng Cui, Jingbin
- 机构：E China Univ Sci & Technol
- 来源：DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY 2006
- 关键词：bicalutamide solid dispersion PVPK30 dissolution rate amorphous state
- Quantitative determination of puerarin in dog plasma by HPLC and study on the relative bioavailability of sustained release tablets被引量：38收藏
- 作者：Ren, Fuzheng Jing, Qiufang Shen, Yongjia Ma, Hongmei Cui, Jingbin
- 机构：E China Univ Sci & Technol
- 来源：JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS 2006
- 关键词：puerarin sustained release tablets Yufengningxin tablets bioavailability HPLC
- PEGylated-PLGA Nanoparticles Coated with pH-Responsive Tannic Acid-Fe(III) Complexes for Reduced Premature Doxorubicin Release and Enhanced Targeting in Breast Cancer被引量：38收藏
- 作者：Hu, Fabiao Zhang, Ruihuan Guo, Wei Yan, Ting He, Xiujuan Hu, Fengzhi Ren, Fuzheng Ma, Xingyuan Lei, Jiandu Zheng, Wenyun
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Beijing Forestry Univ
- 来源：MOLECULAR PHARMACEUTICS 2021
- 关键词：TPLGA NPs premature release effect inhibition chemotherapy drug delivery tumor tissue targeting
- Cannabidiol Effectively Promoted Cell Death in Bladder Cancer and the Improved Intravesical Adhesion Drugs Delivery Strategy Could Be Better Used for Treatment被引量：24收藏
- 作者：Chen, Shanshan Deng, Changping Zheng, Wenyun Li, Shihui Liu, Yuping Zhang, Tong Zhang, Chen Fu, Yunhui Miao, Hui Ren, Fuzheng Ma, Xingyuan
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：PHARMACEUTICS 2021
- 关键词：cannabidiol (CBD) bladder cancer (BC) RNA sequencing PI3K Akt chitosan CBD-loaded PLGA
- Estimating Thermodynamic Stability Relationship of Polymorphs of Sofosbuvir被引量：22收藏
- 作者：Qi, Ming-Hui Hong, Ming-Huang Liu, Yan Wang, En-Fu Ren, Fu-Zheng Ren, Guo-Bin
- 机构：E China Univ Sci & Technol
- 来源：CRYSTAL GROWTH & DESIGN 2015
- 关键词：Solubility - Thermoanalysis - X ray powder diffraction - Free energy - Melting
- A Novel Drug Delivery Carrier Comprised of Nimodipine Drug Solution and a Nanoemulsion: Preparation, Characterization, in vitro, and in vivo Studies被引量：19收藏
- 作者：Huang, Saixu Huang, Zhiyong Fu, Zhiqin Shi, Yamin Dai, Qi Tang, Shuyan Gu, Yongwei Xu, Youfa Chen, Jianming Wu, Xin Ren, Fuzheng
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Shanghai Weier Biol Med Sci & Technol Co Ltd;Fujian Univ Tradit Chinese Med
- 来源：INTERNATIONAL JOURNAL OF NANOMEDICINE 2020
- 关键词：nimodipine nanoemulsion pharmacokinetics MCAO LD50
- Peptide T7-modified polypeptide with disulfide bonds for targeted delivery of plasmid DNA for gene therapy of prostate cancer被引量：19收藏
- 作者：Lu, Yue Jiang, Wenjun Wu, Xin Huang, Saixu Huang, Zhiyong Shi, Yamin Dai, Qi Chen, Jianming Ren, Fuzheng Gao, Shen
- 机构：East China Univ Sci & Technol;Shanghai Weier Biol Med Sci & Technol Co Ltd;Fujian Univ Tradit Chinese Med;Second Mil Med Univ
- 来源：INTERNATIONAL JOURNAL OF NANOMEDICINE 2018
- 关键词：arginine peptide aspartic acid peptide tumor targeting DNA delivery bone metastasis prostate cancer
- Stabilizing Effect of Soluplus on Erlotinib Metastable Crystal Form in Microparticles and Amorphous Solid Dispersions被引量：18收藏
- 作者：Jia, Shuyu Ning, Shangqi Leng, Yuting Jing, Qiufang Xu, Zhongyu Ren, Fuzheng
- 机构：East China Univ Sci & Technol
- 来源：POLYMERS 2022
- 关键词：erlotinib soluplus microparticles solid dispersions stabilization
- Investigating molecular interactions of high-loaded glipizide-HPMCAS microparticles by integrated experimental and modeling techniques被引量：17收藏
- 作者：Li, Qiang Zhao, Qianqian Jing, Qiufang Ma, Xiaosi Chen, Ning Ren, Guobin Ouyang, Defang Ren, Fuzheng
- 机构：East China Univ Sci & Technol;Univ Macau
- 来源：EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES 2019
- 关键词：Glipizide Hydroxypropyl methylcellulose acetate succinate (HPMCAS) Molecular interaction Molecular dynamics simulation
- Influence of Temperature, Solvents, and Excipients on Crystal Transformation of Agomelatine被引量：16收藏
- 作者：Liu, Yan Gao, Huiru Xu, Hao Ren, Fuzheng Ren, Guobin
- 机构：East China Univ Sci & Technol
- 来源：ORGANIC PROCESS RESEARCH & DEVELOPMENT 2016
- 关键词：Temperature
- Photothermal therapy enhance the anti-mitochondrial metabolism effect of lonidamine to renal cell carcinoma in homologous-targeted nanosystem被引量：15收藏
- 作者：Chen, Jiyuan Ren, Fuzheng Cao, Wenfeng Wu, Zhengjie Ju, Guanqun Xiao, Chengwu Wu, Weijia Gao, Shen Xu, Chuanliang Gao, Yuan
- 机构：Fudan Univ;East China Univ Sci & Technol;Second Mil Med Univ
- 来源：NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE 2021
- 关键词：Renal cell carcinoma Lonidamine Polydopamine Photothermal therapy Mitochondrial metabolism
- Codelivery of miR-4638-5p and Docetaxel Based on Redox-Sensitive Polypeptide Micelles as an Improved Strategy for the Treatment of Castration-Resistant Prostate Cancer被引量：15收藏
- 作者：Jiang, Wenjun Gao, Yuan Wang, Zhuo Gong, Chunai Hu, Chuling Ding, Xueying Qiang, Lei Gao, Shen Ren, Fuzheng
- 机构：East China Univ Sci & Technol;Fudan Univ;Second Mil Med Univ
- 来源：MOLECULAR PHARMACEUTICS 2019
- 关键词：codelivery docetaxel miR-4638-5p enhanced effect castration-resistant prostate cancer
- Determination of nelfinavir mesylate as bulk drug and in pharmaceutical dosage form by stability indicating HPLC被引量：14收藏
- 作者：Jing, Qiufang Shen, Yongjia Tang, Yanhui Ren, Fuzheng Yu, Xinhong Hou, Zhian
- 机构：E China Univ Sci & Technol
- 来源：JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS 2006
- 关键词：nelfinavir mesylate reversed-phase HPLC pharmaceutical preparations validation isocratic elution
- Improving the physicochemical properties of bicalutamide by complex formation with bovine serum albumin被引量：12收藏
- 作者：Yang, Congbin Di, Peiwen Fu, JinPing Xiong, Hui Jing, Qiufang Ren, Guobin Tang, Yun Zheng, Wenyun Liu, Guixia Ren, Fuzheng
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES 2017
- 关键词：Bovine serum albumin Bicalutamide Anti-solvent precipitation Interaction Molecular docking
- Solubility of Agomelatine Crystal Form I and Form II in Pure Solvents and (Isopropanol plus Water) Mixtures被引量：12收藏
- 作者：Liu, Yan Gao, Huiru Ren, Fuzheng Ren, Guobin
- 机构：E China Univ Sci & Technol
- 来源：JOURNAL OF CHEMICAL AND ENGINEERING DATA 2015
- Complexes of Felodipine Nanoparticles With Zein Prepared Using a Dual Shift Technique被引量：11收藏
- 作者：Ren, Fuzheng Fu, Jinping Xiong, Hui Cui, Lin Ren, Guobin Guan, Haiying Jing, Qiufang
- 机构：East China Univ Sci & Technol;Shanghai SPH New Asia Pharmaceut Co Ltd
- 来源：JOURNAL OF PHARMACEUTICAL SCIENCES 2018
- 关键词：felodipine zein dual shift technique complexes hydrophobic interaction
- A mixed solvent system for preparation of spherically agglomerated crystals of ascorbic acid被引量：11收藏
- 作者：Ren, Fuzheng Zhou, Yaru Liu, Yan Fu, Jinping Jing, Qiufang Ren, Guobin
- 机构：East China Univ Sci & Technol
- 来源：PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY 2017
- 关键词：Ascorbic acid binary mixed solvent micromeritic properties spherical crystallization
- Modified rivaroxaban microparticles for solid state properties improvement based on drug-protein/polymer supramolecular interactions被引量：11收藏
- 作者：Chen, Ning Di, Peiwen Ning, Shangqi Jiang, Wenjun Jing, Qiufang Ren, Guobin Liu, Yan Tang, Yun Xu, Zhongyu Liu, Guixia Ren, Fuzheng
- 机构：East China Univ Sci & Technol
- 来源：POWDER TECHNOLOGY 2019
- 关键词：Bottom-up Dissolution Molecular docking Rivaroxaban Supramolecular interactions
- Exploring the effect of PVP on the spherical agglomeration process and micromeritic properties of ascorbic acid被引量：10收藏
- 作者：Huang, Saixu Liu, Yan Zhou, Yaru Li, Qiang Ren, Guobin Jing, Qiufang Ren, Fuzheng
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：POWDER TECHNOLOGY 2019
- 关键词：Fourier transform infrared spectroscopy - Spheres - Hydrogen bonds - Nuclear magnetic resonance spectroscopy - Differential scanning calorimetry
- Immuno-Enhancing Effect of Ginsenoside Rh2 Liposomes on Foot-and-Mouth Disease Vaccine被引量：10收藏
- 作者：Miao, Saiya Jing, Qiufang Wang, Xuanyu Zheng, Wenyun Liu, Hui Tang, Liusiqi Wang, Xinzhu Ren, Fuzheng
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Shanghai Baoshan Ctr Dis Control & Prevent;East China Univ Sci & Technol
- 来源：MOLECULAR PHARMACEUTICS 2023
- 关键词：ginsenoside Rh2 liposomes W/O/W emulsion foot-and-mouth disease vaccine immune adjuvant
- Computational fluid dynamics analysis of droplet generation in microfluidic multi-cell coupled systems被引量：10收藏
- 作者：Li, Hongxia Qiao, Du Ren, Fuzheng Li, Honglin Zhu, Weiping Zhao, Danyang Wang, Minjie
- 机构：Dalian Univ Technol;East China Univ Sci & Technol
- 来源：PHYSICS OF FLUIDS 2021
- 关键词：Throughput - Computational fluid dynamics - Computational geometry - Cells - Hydrodynamics - Flow fields - Structural design - Cytology
- Corosolic acid-modified lipid nanoparticles as delivery carriers for DNA vaccines against avian influenza被引量：10收藏
- 作者：Guo, Ziyan Jing, Qiufang Xu, Zhongyu Zhang, Dahe Zheng, Wenyun Ren, Fuzheng
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Suzhou Womei Biol Co Ltd;East China Univ Sci & Technol
- 来源：INTERNATIONAL JOURNAL OF PHARMACEUTICS 2023
- 关键词：Lipid nanoparticles Cholesterol Corosolic acid Avian influenza vaccine Immune responses
- Elucidating respective functions of two domains BIR and C-helix of human IAP survivin for precise targeted regulating mitotic cycle, apoptosis and autophagy of cancer cells被引量：8收藏
- 作者：Hu, Fabiao Pan, Daxia Zheng, Wenyun Yan, Ting He, Xiujuan Ren, Fuzheng Lu, Yiming Ma, Xingyuan
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;Second Mil Med Univ
- 来源：ONCOTARGET 2017
- 关键词：BIR and CC domains survivin cell cycle apoptosis and autophagy breast cancer cells
- Four solid forms of filgotinib hydrochloride: Insight into the crystal structures, properties, stability, and solid-state transitions被引量：7收藏
- 作者：Qi, Ming-Hui Zhang, Qiao-Dan Liu, Yang Ren, Fu-Zheng Ren, Guo-Bin
- 机构：East China Univ Sci & Technol
- 来源：JOURNAL OF MOLECULAR STRUCTURE 2019
- 关键词：Filgotinib hydrochloride Solid forms Solvates Crystal structure Solid-state transition
- Screen for Inhibitors of Crystal Growth to Identify Desirable Carriers for Amorphous Solid Dispersions Containing Felodipine被引量：7收藏
- 作者：Fu, Jinping Cui, Lin Yang, Congbin Xiong, Hui Ren, Guobin Ma, Xingyuan Jing, Qiufang Ren, Fuzheng
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：AAPS PHARMSCITECH 2018
- 关键词：felodipine zein inhibitory effect on crystal growth solid dispersions intermolecular interactions
- Self-Nanoemulsifying Drug Delivery System (SNEddS) of Anethole Trithione by Combined Use of Surfactants被引量：6收藏
- 作者：Ren, Fuzheng Jing, Qiufang Cui, Jingbin Chen, Jianming Shen, Yongjia
- 机构：E China Univ Sci & Technol;Second Mil Med Univ;E China Univ Sci & Technol
- 来源：JOURNAL OF DISPERSION SCIENCE AND TECHNOLOGY 2009
- 关键词：Anethole trithione dissolution self-nanoemulsifying drug delivery system surfactant
- Synthesis and Characterization of D--Tocopheryl Polyethylene Glycol 1000 Succinate-Block-Poly (ε-caprolactone) Copolymer Used as Carriers for Microparticles被引量：6收藏
- 作者：Ren, Fuzheng Jing, Qiufang Cui, Jingbin Shen, Yongjia
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol
- 来源：JOURNAL OF DISPERSION SCIENCE AND TECHNOLOGY 2009
- 关键词：Copolymer D--tocopheryl polyethylene glycol 1000 succinate microparticle poly (epsilon-caprolactone)
- Characterization of ibuprofen microparticle and improvement of the dissolution被引量：5收藏
- 作者：Ren, Fuzheng Su, Jianping Xiong, Hui Tian, Ying Ren, Guobin Jing, Qiufang
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY 2017
- 关键词：Cremophor RH40 dissolution ibuprofen microparticle Tween 80
