张杰 收藏
( 任职于 生物工程学院)
生物化工专业：硕士生导师、 食品科学专业：硕士生导师、 生物工程领域：工程硕士导师、 食品工程领域：工程硕士导师 博士，副教授，硕士生导师 学习经历 2001-2006 博士，瑞士苏黎世联邦高等工业学院(ETHZ), 生物技术专业,导师Bernard Witholt教授 1998-2001 硕士，华东理工大学化学与制药学院，应用化学专业, 导师周其林教授 1993-1997 学士，华东理工大学化学与制药学院，化学制药专业 工作经历 2009.12&mda... 详细>>
- Highly efficient synthesis of chiral alcohols with a novel NADH-dependent reductase from Streptomyces coelicolor被引量：129收藏
- 作者：Wang, Li-Juan Li, Chun-Xiu Ni, Yan Zhang, Jie Liu, Xiang Xu, Jian-He
- 机构：E China Univ Sci & Technol;Jiangnan Univ
- 来源：BIORESOURCE TECHNOLOGY 2011
- 关键词：Carbonyl reductase Streptomyces coelicolor Asymmetric reduction Ethyl (S)-4-chloro-3-hydroxybutanoate NADH regeneration
- 质疑
- Biocatalytic properties of a recombinant aldo-keto reductase with broad substrate spectrum and excellent stereoselectivity被引量：68收藏
- 作者：Ni, Yan Li, Chun-Xiu Ma, Hong-Min Zhang, Jie Xu, Jian-He
- 机构：E China Univ Sci & Technol
- 来源：APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 2011
- 关键词：YtbE Recombinant aldo-keto reductase Bacillus sp. Asymmetric reduction Chiral alcohols
- 质疑
- Efficient Synthesis of a Chiral Precursor for Angiotensin-Converting Enzyme (ACE) Inhibitors in High Space-Time Yield by a New Reductase without External Cofactors被引量：61收藏
- 作者：Shen, Nai-Dong Ni, Yan Ma, Hong-Min Wang, Li-Juan Li, Chun-Xiu Zheng, Gao-Wei Zhang, Jie Xu, Jian-He
- 机构：E China Univ Sci & Technol
- 来源：ORGANIC LETTERS 2012
- 质疑
- Stereoselective synthesis of L-tert-leucine by a newly cloned leucine dehydrogenase from Exiguobacterium sibiricum被引量：58收藏
- 作者：Li, Jing Pan, Jiang Zhang, Jie Xu, Jian-He
- 机构：E China Univ Sci & Technol
- 来源：JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC 2014
- 关键词：Leucine dehydrogenase Exiguobacterium sibiricum Reductive amination Dual enzyme co-expression L-tert-Leucine
- 质疑
- Stereospecific Reduction of Methyl o-Chlorobenzoylformate at 300 g?L-1 without Additional Cofactor using a Carbonyl Reductase Mined from Candida glabrata被引量：57收藏
- 作者：Ma, Hongmin Yang, Linlin Ni, Yan Zhang, Jie Li, Chun-Xiu Zheng, Gao-Wei Yang, Huaiyu Xu, Jian-He
- 机构：E China Univ Sci & Technol;Chinese Acad Sci
- 来源：ADVANCED SYNTHESIS & CATALYSIS 2012
- 关键词：bioinformatics biotransformations cofactors oxidoreductases
- 质疑
- Efficient Reduction of Ethyl 2-Oxo-4-phenylbutyrate at 620 g.L-1 by a Bacterial Reductase with Broad Substrate Spectrum被引量：50收藏
- 作者：Ni, Yan Li, Chun-Xiu Zhang, Jie Shen, Nai-Dong Bornscheuer, Uwe T. Xu, Jian-He
- 机构：E China Univ Sci & Technol;Ernst Moritz Arndt Univ Greifswald
- 来源：ADVANCED SYNTHESIS & CATALYSIS 2011
- 关键词：alcohols asymmetric catalysis cofactor oxidoreductases reduction
- 质疑
- Highly stereoselective reduction of prochiral ketones by a bacterial reductase coupled with cofactor regeneration被引量：46收藏
- 作者：Ni, Yan Li, Chun-Xiu Wang, Li-Juan Zhang, Jie Xu, Jian-He
- 机构：E China Univ Sci & Technol
- 来源：ORGANIC & BIOMOLECULAR CHEMISTRY 2011
- 关键词：Aromatic compounds - Bacteriology - Enantiomers - Ketones
- 质疑
- A novel D-mandelate dehydrogenase used in three-enzyme cascade reaction for highly efficient synthesis of non-natural chiral amino acids被引量：40收藏
- 作者：Fan, Chang-Wei Xu, Guo-Chao Ma, Bao-Di Bai, Yun-Peng Zhang, Jie Xu, Jian-He
- 机构：E China Univ Sci & Technol
- 来源：JOURNAL OF BIOTECHNOLOGY 2015
- 关键词：D-Mandelate dehydrogenase L-Phenylglycine Asymmetric synthesis Cascade reaction Process optimization
- 质疑
- Highly efficient synthesis of chiral alcohols with a novel NADH-dependent reductase from Streptomyces coelicolor被引量：34收藏
- 作者：Wang, Li-Juan Li, Chun-Xiu Ni, Yan Zhang, Jie Liu, Xiang Xu, Jian-He
- 机构： Laboratory of Biocatalysis and Synthetic Biotechnology; School of Chemical and Material Engineering
- 来源：Bioresource Technology 2011
- 关键词：Enzyme activity - Ketones - Escherichia coli
- 质疑
- Crystal structures of Pseudomonas putida esterase reveal the functional role of residues 187 and 287 in substrate binding and chiral recognition被引量：24收藏
- 作者：Dou, Shuai Kong, Xu-Dong Ma, Bao-Di Chen, Qi Zhang, Jie Zhou, Jiahai Xu, Jian-He
- 机构：E China Univ Sci & Technol;Chinese Acad Sci;Wuhan Univ
- 来源：BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 2014
- 关键词：Crystal structure Pseudomonas putida esterase Enzyme-substrate complex Chiral recognition Activity enhancement Protein engineering
- 质疑
- Bioreduction of methyl o-chlorobenzoylformate at 500 g L-1 without external cofactors for efficient production of enantiopure clopidogrel intermediate被引量：22收藏
- 作者：Ni, Yan Pan, Jiang Ma, Hong-Min Li, Chun-Xiu Zhang, Jie Zheng, Gao-Wei Xu, Jian-He
- 机构：E China Univ Sci & Technol
- 来源：TETRAHEDRON LETTERS 2012
- 关键词：Asymmetric reduction Aldo-keto reductase Whole-cell catalyst Methyl (R)-o-chloromandelate Clopidogrel
- 质疑
- Relative humidity-triggered polyamide 4/Cinnamaldehyde core-shell nanofibers for antibacterial packaging被引量：16收藏
- 作者：Wang, Ziying Zhan, Fangke Zhang, Di Wang, Yibing Qiu, Yongjun Zhang, Jie Wang, Li Zhao, Liming
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol SCI
- 来源：JOURNAL OF FOOD ENGINEERING 2023
- 关键词：Polyamide 4 Cinnamaldehyde Coaxial electrospinning RH-Triggered Active packaging
- 质疑
- Efficient production of ethyl (R)-2-hydroxy-4-phenylbutyrate using a cost-effective reductase expressed in Pichia pastoris被引量：8收藏
- 作者：Qian, Xiao-Long Pan, Jiang Shen, Nai-Dong Ju, Xin Zhang, Jie Xu, Jian-He
- 机构：E China Univ Sci & Technol
- 来源：BIOCHEMICAL ENGINEERING JOURNAL 2014
- 关键词：Biocatalysis (R)-HPBE Enzyme production Recombinant Pichia pastoris Fermentation Cost-effective reductase Fed-batch culture
- 质疑
- Optogenetic control of Corynebacterium glutamicum gene expression被引量：8收藏
- 作者：Deng, Chen Xin, Ruijie Li, Xingjian Zhang, Jie Fan, Liqiang Qiu, Yongjun Zhao, Liming
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：NUCLEIC ACIDS RESEARCH 2024
- 质疑
- 不同菌种发酵对诺丽果酵素的抗氧化性及风味物质的影响被引量：4收藏
- 作者：刘倩 袁越 张杰 赵瑞丽 赵黎明
- 机构：华东理工大学生物工程学院;华东理工大学生物工程学院;上海皇润食品科技有限公司
- 来源：《食品工业科技》 2023
- 关键词：诺丽果酵素 乳酸菌 双歧杆菌 抗氧化活性 风味物质
- 摘要：为比较不同菌种发酵对诺丽果酵素品质的影响,选用鼠李糖乳杆菌12(LGG)、植物乳杆菌08(LP-08)、植物乳杆菌K11(LP-K11)、戊糖片球菌03(PP)、乳双歧杆菌36(BLA)分别对诺丽果汁进行发酵,比较不同菌...
- 下载全文在线阅读质疑
- Enhanced heparosan biosynthesis in Corynebacterium glutamicum by systematic metabolic engineering and translation-level fine-tuning被引量：0收藏
- 作者：Zhang, Jie Cui, Yanan Zhang, Peiyi Zhao, Mengqi Fan, Liqiang Li, Xu Deng, Chen Zhao, Liming
- 机构：East China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol SCI
- 来源：BIORESOURCES AND BIOPROCESSING 2026
- 关键词：Heparosan
Corynebacterium glutamicum Systematic metabolic engineering Translation-level fine-tuning Fed-batch fermentation - 质疑
- Novel iterative genome mining and engineering of a bifunctional KvVDH enable selective production of furan carboxylic acids from high-concentration 5-hydroxymethylfurfural被引量：0收藏
- 作者：Cui, Yanan Zhang, Jie Xing, Xijun Zhang, Hanwen Chen, Yutong Fan, Liqiang Li, Xu Qiu, Yongjun Deng, Chen Zhao, Liming
- 机构：East China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol SCI;East China Univ Sci & Technol
- 来源：GREEN CHEMISTRY 2026
- 关键词：Biosynthesis - Carboxylic acids - Catalysis - Catalyst activity - Computational efficiency - Conformations - Enzymes - Genes - Genome - Hydrogen bonds - Iterative methods - Screening
- 质疑
- Combined Anserine/Carnosine Exerts Anti-Hyperuricemic, Nephroprotective, and Gut Microbiota-Modulating Effects in Hyperuricemia Mice被引量：0收藏
- 作者：Huang, Jingjing Dang, Zheng Zhang, Yuzhi Lin, Haisheng Du, Lei Zhang, Jie Zhao, Li Chang, William T. H. Kong, Xiang-Ru Tseng, Wei-Ting Xie, Jingli
- 机构：East China Univ Sci & Technol;Guangdong Ocean Univ;Lytone Enterprise Inc;Shanghai Lytone Biochem LTD;Shanghai Collaborat Innovat Ctr Biomfg
- 来源：FOOD BIOENGINEERING 2026
- 关键词：carnosine and anserine correlation analysis gut microbiota hyperuricemia kidney protection
- 质疑
