成果/Result
- Synthetic ePTFE Grafts Coated with an Anti-CD133 Antibody-Functionalized Heparin/Collagen Multilayer with Rapid in vivo Endothelialization Properties被引量：92收藏
- 作者：Lu, Shuyang Zhang, Peng Sun, Xiaoning Gong, Feirong Yang, Shouguo Shen, Li Huang, Zheyong Wang, Chunsheng
- 机构：Fudan Univ;Fudan Univ;Fudan Univ;E China Univ Sci & Technol
- 来源：ACS APPLIED MATERIALS & INTERFACES 2013
- 关键词：ePTFE grafts surface modification endothelialization endothelial cells platelet adhesion
- Heparin-immobilized polymers as non-inflammatory and non-thrombogenic coating materials for arsenic trioxide eluting stents被引量：72收藏
- 作者：Gong, Feirong Cheng, Xiaoyan Wang, Shanfeng Zhao, Yanchao Gao, Yun Cai, Haibo
- 机构：Univ Tennessee;E China Univ Sci & Technol;E China Univ Sci & Technol
- 来源：ACTA BIOMATERIALIA 2010
- 关键词：Stent Biodegradability Heparin Arsenic trioxide (As2O3) Restenosis
- Curcumin-Loaded Blood-Stable Polymeric Micelles for Enhancing Therapeutic Effect on Erythroleukemia被引量：38收藏
- 作者：Gong, Feirong Chen, Dan Teng, Xin Ge, Junhua Ning, Xianfeng Shen, Ya-ling Li, Jian Wang, Shanfeng
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Qingdao Univ;Univ Tennessee
- 来源：MOLECULAR PHARMACEUTICS 2017
- 关键词：curcumin polymer micelles blood-stable antitumor
- Biodegradable comb-dendritic tri-block copolymers consisting of poly(ethylene glycol) and poly(L-lactide): Synthesis, characterizations, and regulation of surface morphology and cell responses被引量：30收藏
- 作者：Gong, Feirong Cheng, Xiaoyan Wang, Shanfeng Wang, Yang Gao, Yun Cheng, Shujun
- 机构：Univ Tennessee;E China Univ Sci & Technol;Fudan Univ
- 来源：POLYMER 2009
- 关键词：Polylactide Comb-dendritic tri-block copolymer Cell responses
- Preparation, characterization, in vivo pharmacokinetics, and biodistribution of polymeric micellar dimethoxycurcumin for tumor targeting被引量：29收藏
- 作者：Liu, Hui Xu, Hui Jiang, Yunxia Hao, Shengyuan Gong, Feirong Mu, Hongjie Liu, Ke
- 机构：Yantai Univ;E China Univ Sci & Technol;Suzhou Nanomed R&D Co Ltd
- 来源：INTERNATIONAL JOURNAL OF NANOMEDICINE 2015
- 关键词：dimethoxycurcumin polymeric micelles characterization pharmacokinetic profile biodistribution tumor targeting
- A novel cabazitaxel-loaded polymeric micelle system with superior in vitro stability and long blood circulation time被引量：27收藏
- 作者：Han, Xiaoxiong Chen, Dan Sun, Jing Zhou, Jinsong Li, Duan Gong, Feirong Shen, Yaling
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol;E China Univ Sci & Technol;Shanghai Yizhong Biotech Co Ltd
- 来源：JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION 2016
- 关键词：stability polymeric micelle blood circulation time Cabazitaxel
- Fast and convenient synthesis of amine-terminated polylactide as a macroinitiator for ω-benzyloxycarbonyl-L-lysine-N-carboxyanhydrides被引量：27收藏
- 作者：Ju, Mingjie Gong, Feirong Cheng, Shujun Gao, Yun
- 机构： Key Laboratory for Ultrafine Materials of Ministry of Education
- 来源：International Journal of Polymer Science 2011
- 关键词：Ring opening polymerization - Molecular weight
- Drug-interactive mPEG-b-PLA-Phe(Boc) micelles enhance the tolerance and anti-tumor efficacy of docetaxel被引量：26收藏
- 作者：Gong, Feirong Wang, Rongrong Zhu, Zhengquan Duan, Jiayao Teng, Xin Cui, Zhong-Kai
- 机构：East China Univ Sci & Technol;Southern Med Univ;Southern Med Univ;Guangzhou Regenerat Med & Hlth Guangdong Lab
- 来源：DRUG DELIVERY 2020
- 关键词：Polymeric micelles docetaxel anti-tumor efficacy
- Polycarbonate urethane films modified by heparin to enhance hemocompatibility and endothelialization被引量：22收藏
- 作者：Lu, Yue Shen, Li Gong, Feirong Cui, Jiayang Rao, Ju Chen, Jianding Yang, Wei
- 机构：Harbin Med Univ;E China Univ Sci & Technol;Fudan Univ;Zhejiang Univ Technol
- 来源：POLYMER INTERNATIONAL 2012
- 关键词：polyurethane heparin inflammation stent
- Synthesis, characterization, and in vitro evaluation of TRAIL-modified, cabazitaxel -loaded polymeric micelles for achieving synergistic anticancer therapy被引量：16收藏
- 作者：Feng, Caochuan Han, Xiaoxiong Chi, Lili Sun, Jing Gong, Feirong Shen, Yaling
- 机构：East China Univ Sci & Technol;Shandong Univ Tradit Chinese Med;Shanghai Gebaide Biotechn Co Ltd;East China Univ Sci & Technol
- 来源：JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION 2018
- 关键词：Cabazitaxel TRAIL polymeric micelles synergism anticancer
- Synergistic effect of the anti-PD-1 antibody with blood stable and reduction sensitive curcumin micelles on colon cancer被引量：16收藏
- 作者：Gong, Feirong Ma, Jian-Chao Jia, Jianguo Li, Fa-Zhan Wu, Jiao-Lan Wang, Shanfeng Teng, Xin Cui, Zhong-Kai
- 机构：East China Univ Sci & Technol;Southern Med Univ;Southern Med Univ;Fudan Univ;Sun Yat sen Univ
- 来源：DRUG DELIVERY 2021
- 关键词：Telodendrimer micelles glutathione-triggered release bioavailability synergistic effect cancer immunotherapy
- Glutathione-responsive core cross-linked micelles for controlled cabazitaxel delivery被引量：16收藏
- 作者：Han, Xiaoxiong Gong, Feirong Sun, Jing Li, Yueqi Liu, XiaoFei Chen, Dan Liu, Jianwen Shen, Yaling
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：JOURNAL OF NANOPARTICLE RESEARCH 2018
- 关键词：Cabazitaxel Glutathione-responsive Polymeric micelles Solubility Endocytosis mechanism Biomedicine
- 新型生物可降解心血管涂层支架的制备及其生物相容性的研究被引量：14收藏
- 作者：赵燕超 刘学波 葛均波 龚飞荣 陈功雨 胡源浚 程树军 陈建定
- 机构：华东理工大学材料科学与工程学院超细材料制备与应用教育部重点实验室;复旦大学附属中山医院上海市心血管病研究所
- 来源：《中国生物医学工程学报》 2008
- 关键词：肝素化 生物可降解涂层 聚乳酸共聚物 心血管支架 再狭窄
- 摘要：采用共价键连接技术,以二环己基碳化二亚胺(DCC)为偶联剂,将肝素与具有官能侧基的脱保护聚乳酸和吗啉二酮衍生物共聚物材料连接,肝素本体重量含量达到15%。与共混肝素材料的肝素体外释放实验对比结果证明该连接技术对肝素有良好...
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- Characterization of tissue responses and degradation behavior of heparin-immobilized copolymer for drug-eluting stents被引量：13收藏
- 作者：Shen, Li Li, Zhenru Gong, Feirong Zhang, Feng Qin, Qing Cheng, Shujun Ge, Junbo
- 机构：Fudan Univ;Peoples Hosp Shanghai Putuo Dist;E China Univ Sci & Technol
- 来源：POLYMER DEGRADATION AND STABILITY 2013
- 关键词：Stent Coating Biodegradable Tissue response
- Novel branched poly(l-lactide) with poly(glycerol-co-sebacate) core被引量：12收藏
- 作者：Cheng, Shujun Yang, Lijing Gong, Feirong
- 机构：E China Univ Sci & Technol
- 来源：POLYMER BULLETIN 2010
- 关键词：Polylactide PGS Branched Copolymer
- Fast and Convenient Synthesis of Amine-Terminated Polylactide as a Macroinitiator for ω-Benzyloxycarbonyl-L-Lysine-N-Carboxyanhydrides被引量：12收藏
- 作者：Ju, Mingjie Gong, Feirong Cheng, Shujun Gao, Yun
- 机构：E China Univ Sci & Technol
- 来源：INTERNATIONAL JOURNAL OF POLYMER SCIENCE 2011
- 大黄素洗脱可降解涂层支架的制作及其体内外实验研究被引量：11收藏
- 作者：赵燕超 龚飞荣 葛均波 程树军 陈建定
- 机构：华东理工大学材料科学与工程学院;复旦大学附属中山医院上海市心血管病研究所
- 来源：《华东理工大学学报（自然科学版）》 2008
- 关键词：肝素化共聚物 大黄素洗脱支架 再狭窄 体内实验 可降解涂层
- 摘要：以肝素化吗啉二酮苄酯与L-丙交酯的共聚物材料作为药物支架可降解涂层的药物载体材料,大黄素作为药物,在自制的计算机控制的喷涂设备上成功制备了大黄素药物洗脱支架(药物含量(150±5)μg)。并研究了大黄素支架在体外磷酸盐缓...
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- Design and evaluation of mPEG-PLA micelles functionalized with drug-interactive domains as improved drug carriers for docetaxel delivery被引量：10收藏
- 作者：Qi, Dingqing Gong, Feirong Teng, Xin Ma, Mingming Wen, Huijing Yuan, Weihao Cheng, Yi Lu, Chong
- 机构：East China Univ Sci & Technol
- 来源：JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION 2017
- 关键词：Micelle 9-Fluorenylmethoxycarbonyl drug-interactive docetaxel drug delivery
- Hyaluronan Immobilized Polyurethane as a Blood Contacting Material被引量：10收藏
- 作者：Gong, Feirong Lu, Yue Guo, Hui Cheng, Shujun Gao, Yun
- 机构：E China Univ Sci & Technol
- 来源：INTERNATIONAL JOURNAL OF POLYMER SCIENCE 2010
- 关键词：Endothelial cells - Hyaluronic acid - Fourier transform infrared spectroscopy - Infrared reflection - Blood - Scanning electron microscopy
- Novel side chain dendronized polyurethane: synthesis, characteristics, and cell responses被引量：10收藏
- 作者：Rao, Ju Gong, Feirong Cheng, Shujun Chen, Jianding
- 机构：E China Univ Sci & Technol
- 来源：POLYMER BULLETIN 2009
- 关键词：Polyurethane Dendron Biocompatibility
- Anti-Inflammatory Effects of Arsenic Trioxide Eluting Stents in a Porcine Coronary Model被引量：10收藏
- 作者：Shen, Li Gong, Feirong Tian, Wenjie Li, Weiming Zhang, Feng Qian, Juying Sun, Aijun Zou, Yunzeng Yang, Wei Ge, Junbo
- 机构：Fudan Univ;E China Univ Sci & Technol;Sichuan Prov Peoples Hosp;Harbin Med Univ
- 来源：BIOMED RESEARCH INTERNATIONAL 2013
- Novel polyurethane immobilized with heparin被引量：9收藏
- 作者：Wang, Jun-Bin Zhao, Yan-Chao Gong, Fei-Rong Rao, Ju Cheng, Shu-Jun
- 机构： Key Laboratory for Ultra fine Materials
- 来源：Huadong Ligong Daxue Xuebao /Journal of East China University of Science and Technology 2008
- Cancer-targeted and glutathione-responsive micellar carriers for controlled delivery of cabazitaxel被引量：8收藏
- 作者：Han, Xiaoxiong Gong, Feirong Chi, Lili Feng, Caochuan Sun, Jing Chen, Yiyang Liu, Jianwen Shen, Yaling
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Shandong Univ Tradit Chinese Med;East China Univ Sci & Technol
- 来源：NANOTECHNOLOGY 2019
- 关键词：GSH-responsive tumor-targeting peptide cabazitaxel polymeric micelles
- 二乙酸甘油酯封端的齐聚L-丙交酯增塑改性聚L-丙交酯薄膜被引量：7收藏
- 作者：郭其魁 桂宗彦 龚飞荣 程树军 陆冲
- 机构：华东理工大学材料科学与工程学院超细材料制备与应用教育部重点实验室
- 来源：《功能高分子学报》 2009
- 关键词：聚丙交酯 二乙酸甘油酯 封端 改性 生物相容性
- 摘要：以二乙酸甘油酯(GD)引发L-丙交酯(LLA)开环聚合合成了二乙酸甘油酯封端的齐聚L-丙交酯(OGLA),并以此为增塑剂,以溶液共混法制备了OGLA与高分子量聚L-丙交酯(PLLA)的共混膜。采用DSC研究了共混膜的Tg...
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- Synthesis and characterization of new biodegradable comb-dendritic triblock copolymers被引量：7收藏
- 作者：Ju, Mingjie Shen, Li Gong, Feirong Gao, Yun Zhang, Weian
- 机构：E China Univ Sci & Technol;Fudan Univ
- 来源：POLYMER INTERNATIONAL 2012
- 关键词：dumbbell-shaped triblock copolymers ring-opening polymerization microsphere double emulsion
- 树枝状大分子改性聚乙二醇生物材料的制备与研究被引量：7收藏
- 作者：王坚 程树军 龚飞荣
- 机构：华东理工大学材料科学与工程学院超细材料制备与应用教育部重点实验室
- 来源：《化工新型材料》 2009
- 关键词：树枝状大分子 聚乙二醇 生物材料
- 摘要：采用了新的"酸酐法"使用2,2-二羟甲基丙酸(DMPA)来合成一种具有规整结构树枝状大分子。制备好的树枝状大分子通过高效酯化反应接枝到聚乙二醇(PEG)两端,形成结构高度支化、表面官能团密度大、单分散性的大分子。树枝状大...
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- 环状碳酸酯共聚改性聚乳酸性能被引量：6收藏
- 作者：饶炬 龚飞荣 陈建定 程树军
- 机构：华东理工大学材料科学与工程学院超细材料制备与应用教育部重点实验室
- 来源：《华东理工大学学报（自然科学版）》 2009
- 关键词：聚左旋丙交酯 碳酸酯 共聚 改性
- 摘要：将5-甲基-5-苄氧羰基-三亚甲基碳酸酯(MBC)与左旋丙交酯(LLA)开环共聚制备了乳酸-功能化碳酸酯共聚物(P(LLA-MBC)),研究了共聚物的力学性能、体外降解性能及生物相容性。结果表明:与聚左旋丙交酯(PLLA...
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- 树枝状聚L-丙交酯-dendron-聚乙二醇-dendron-聚L-丙交酯的自组装被引量：6收藏
- 作者：谢威 龚飞荣 江琳 戎宗明 程树军
- 机构：华东理工大学化学与分子工程学院;华东理工大学材料科学与工程学院
- 来源：《华东理工大学学报（自然科学版）》 2010
- 关键词：树枝状聚合物 胶束 自组装 聚L-丙交酯 聚乙二醇
- 摘要：运用1H-NMR和GPC对所合成的树枝状大分子聚L-丙交酯-dendron-聚乙二醇-den-dron-聚L-丙交酯进行表征,结果显示该聚合物具有预期的结构。在混合溶剂四氢呋喃/水中,聚合物通过自组装形成胶束。通过扫描电...
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- 姜黄素缓释胶束的制备、表征及其抗细胞毒类药物的多药耐药性评价被引量：6收藏
- 作者：李晨晨 龚飞荣 程树军 韩肖雄 张玲玲
- 机构：华东理工大学材料科学与工程学院
- 来源：《华东理工大学学报(自然科学版)》 2014
- 关键词：姜黄素 胶束 生物利用度 多药耐药
- 摘要：姜黄素为传统中药姜黄中提取的多酚类化合物,具有多靶点的抗肿瘤活性及确切的抗炎和抗氧化等作用。但姜黄素几乎不溶于水,口服不吸收,且存在严重的肝首过效应,因此系统生物利用度很低,难以充分发挥其抗肿瘤活性。合成了叔丁氧羰基苯丙...
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- Anti-CD133 Antibody Immobilized on the Surface of Stents Enhances Endothelialization被引量：6收藏
- 作者：Li, Jian Li, Dan Gong, Feirong Jiang, Shaoyan Yu, Hua An, Yi
- 机构：Qingdao Univ;E China Univ Sci & Technol
- 来源：BIOMED RESEARCH INTERNATIONAL 2014
