成果/Result
- Enhancing Photodynamic Therapy Efficacy by Using Fluorinated Nanoplatform被引量：149收藏
- 作者：Que, Yurong Liu, Yajing Tan, Wei Feng, Chun Shi, Ping Li, Yongjun XiaoyuHuang
- 机构：Chinese Acad Sci;E China Univ Sci & Technol
- 来源：ACS MACRO LETTERS 2016
- Semifluorinated Synergistic Nonfouling/Fouling-Release Surface被引量：129收藏
- 作者：Xu, Binbin Liu, Yajing Sun, Xiaowen Hu, Jianhua Shi, Ping Huang, Xiaoyu
- 机构：Chinese Acad Sci;Fudan Univ;East China Univ Sci & Technol
- 来源：ACS APPLIED MATERIALS & INTERFACES 2017
- 关键词：molecular brush antifouling surfaces nonfouling fouling-release spin-casting
- In Situ Ratiometric Quantitative Tracing of Intracellular Leucine Aminopeptidase Activity via an Activatable Near-Infrared Fluorescent. Probe被引量：87收藏
- 作者：Gu, Kaizhi Liu, Yajing Guo, Zhiqian Lian, Cheng Yan, Chenxu Shi, Ping Tian, He Zhu, Wei-Hong
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;Dalian Univ Technol
- 来源：ACS APPLIED MATERIALS & INTERFACES 2016
- 关键词：near-infrared fluorescent probe ratiometric in situ leucine aminopeptidase
- A sequence-activated AND logic dual-channel fluorescent probe for tracking programmable drug release被引量：85收藏
- 作者：Yan, Chenxu Guo, Zhiqian Liu, Yajing Shi, Ping Tian, He Zhu, Wei-Hong
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：CHEMICAL SCIENCE 2018
- 关键词：Infrared devices - Controlled drug delivery - Fluorescence - Computer circuits - Diagnosis - Tumors - Biomarkers - Targeted drug delivery
- A novel near-infrared fluorescent probe with a large stokes shift for the detection and imaging of biothiols被引量：83收藏
- 作者：Wang, Kai Leng, Taohua Liu, Yajing Wang, Chengyun Shi, Ping Shen, Yongjia Zhu, Wei-Hong
- 机构：East China Univ & Technol;East China Univ & Technol;Shanghai Inst Qual Inspect & Tech Res;East China Univ Sci & Technol
- 来源：SENSORS AND ACTUATORS B-CHEMICAL 2017
- 关键词：Isophorone-based dye Near-infrared fluorescence Large stokes shift Biothiols Cell imaging
- Unraveling and engineering the production of 23,24-bisnorcholenic steroids in sterol metabolism被引量：80收藏
- 作者：Xu, Li-Qin Liu, Yong-Jun Yao, Kang Liu, Hao-Hao Tao, Xin-Yi Wang, Feng-Qing Wei, Dong-Zhi
- 机构：E China Univ Sci & Technol
- 来源：SCIENTIFIC REPORTS 2016
- GSH-Activated NIR Fluorescent Prodrug for Podophyllotoxin Delivery被引量：68收藏
- 作者：Liu, Yajing Zhu, Shaojia Gu, Kaizhi Guo, Zhiqian Huang, Xiaoyu Wang, Mingwei Amin, Hesham M. Zhu, Weihong Shi, Ping
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Chinese Acad Sci;Fudan Univ;Univ Texas MD Anderson Canc Ctr
- 来源：ACS APPLIED MATERIALS & INTERFACES 2017
- 关键词：PPT prodrug NIR fluorescent reporter DCM-S-PPT mPEG-DSPE
- Photocaged prodrug under NIR light-triggering with dual-channel fluorescence: in vivo real-time tracking for precise drug delivery被引量：63收藏
- 作者：Guo, Zhiqian Ma, Yaguang Liu, Yajing Yan, Chenxu Shi, Ping Tian, He Zhu, Wei-Hong
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：SCIENCE CHINA-CHEMISTRY 2018
- 关键词：near-infrared cyanine dye dual-channel fluorescence drug-release photocage tumor targeting
- Morphology Tuning of Aggregation-Induced Emission Probes by Flash Nanoprecipitation: Shape and Size Effects on in Vivo Imaging被引量：51收藏
- 作者：Wang, Mingwei Xu, Yisheng Liu, Yajing Gu, Kaizhi Tan, Jinchao Shi, Ping Yang, Dahai Guo, Zhiqian Zhu, Weihong Guo, Xuhong Stuart, Martien A. Cohen
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;Shihezi Univ
- 来源：ACS APPLIED MATERIALS & INTERFACES 2018
- 关键词：aggregation-induced emission quinolinemalononitrile nanoparticle morphology flash nanoprecipitation in vivo imaging fluorescence
- Water-soluble rhodamine-based chemosensor for Fe3+ with high sensitivity, selectivity and anti-interference capacity and its imaging application in living cells被引量：49收藏
- 作者：Zhou, Feng Leng, Tao-Hua Liu, Ya-Jing Wang, Cheng-Yun Shi, Ping Zhu, Wei-Hong
- 机构：East China Univ & Technol;East China Univ & Technol;Natl Food Qual Supervis & Inspect Ctr Shanghai;East China Univ Sci & Technol
- 来源：DYES AND PIGMENTS 2017
- 关键词：Rhodamine dye Chemosensors Fe3+ Naked-eye detection Living cell imaging
- Enhancing the bioconversion of phytosterols to steroidal intermediates by the deficiency of kasB in the cell wall synthesis of Mycobacterium neoaurum被引量：45收藏
- 作者：Xiong, Liang-Bin Liu, Hao-Hao Zhao, Ming Liu, Yong-Jun Song, Lu Xie, Zhi-Yong Xu, Yi-Xin Wang, Feng-Qing Wei, Dong-Zhi
- 机构：Shanghai Univ Med & Hlth Sci;East China Univ Sci & Technol;Shanghai Univ Med & Hlth Sci
- 来源：MICROBIAL CELL FACTORIES 2020
- 关键词：Mycolic acids Self-enhancement conversion beta-Ketoacyl-acyl carrier protein synthase Phytosterol Steroid intermediates
- Rational design of novel near-infrared fluorescent DCM derivatives and their application in bioimaging被引量：43收藏
- 作者：Wang, Xiaohang Guo, Zhiqian Zhu, Shiqin Liu, Yajing Shi, Ping Tian, He Zhu, Wei-Hong
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;Dalian Univ Technol
- 来源：JOURNAL OF MATERIALS CHEMISTRY B 2016
- 关键词：Photobleaching - Fluorescence - Infrared devices - Signal to noise ratio
- Characterization and engineering control of the effects of reactive oxygen species on the conversion of sterols to steroid synthons in Mycobacterium neoaurum被引量：29收藏
- 作者：Sun, Wan-Ju Wang, Li Liu, Hao-Hao Liu, Yong-Jun Ren, Yu-Hong Wang, Feng-Qing Wei, Dong-Zhi
- 机构：East China Univ Sci & Technol
- 来源：METABOLIC ENGINEERING 2019
- 关键词：Sterol catabolism Reactive oxygen species Catalase Mycothiol Ergothioneine Mycobacteria
- Transformation of phytosterols into pregnatetraenedione by a combined microbial and chemical process被引量：18收藏
- 作者：Liu, Yong-Jun Ji, Wei-ting Song, Lu Tao, Xin-Yi Zhao, Ming Gao, Bei Meng, Hao Wang, Feng-Qing Wei, Dong-Zhi
- 机构：East China Univ Sci & Technol;Hunan Norchem Pharmaceut Co Ltd
- 来源：GREEN CHEMISTRY 2022
- 关键词：Alcohols - Carboxylation - Drug products - Metabolism - Metabolites - Polyols
- Near-infrared fluorescent dyes with large Stokes shifts: light generation in BODIPYs undergoing excited state intramolecular proton transfer被引量：15收藏
- 作者：Fei, Qiang Gu, Xianfeng Liu, Yajing Shi, Ben Liu, Hengyan Xu, Ge Li, Chunbao Shi, Ping Zhao, Chunchang
- 机构：Tianjin Univ;East China Univ Sci & Technol;East China Univ Sci & Technol;Fudan Univ;East China Univ Sci & Technol
- 来源：ORGANIC & BIOMOLECULAR CHEMISTRY 2017
- 关键词：Proton transfer - Excited states - Infrared devices
- Enhancement of 9α-Hydroxy-4-androstene-3,17-dione Production from Soybean Phytosterols by Deficiency of a Regulated Intramembrane Proteolysis Metalloprotease in Mycobacterium neoaurum被引量：14收藏
- 作者：Xiong, Liang-Bin Sun, Wan-Ju Liu, Yong Jun Wang, Feng-Qing Wei, Dong-Zhi
- 机构：East China Univ Sci & Technol
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2017
- 关键词：Mycobacterium 9 alpha-hydroxy-4-androstene-3,17-dione (9-OHAD) soybean phytosterol rip1 sigD
- Facile synthesis of manganese silicate nanoparticles for pH/GSH-responsive T1-weighted magnetic resonance imaging被引量：12收藏
- 作者：Li, X. W. Zhao, W. R. Liu, Y. J. Liu, X. H. Shi, P. Li, Y. S. Shi, J. L.
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Fudan Univ;Chinese Acad Sci
- 来源：JOURNAL OF MATERIALS CHEMISTRY B 2016
- 关键词：Cost effectiveness - Synthesis (chemical) - Biocompatibility - Cytotoxicity - Silicates - Tissue - Solutions - Diagnosis - Manganese compounds - Nanomagnetics - Nanoparticles
- Improving the biotransformation efficiency of soybean phytosterols in Mycolicibacterium neoaurum by the combined deletion of fbpC3 and embC in cell envelope synthesis被引量：12收藏
- 作者：Xiong, Liang-Bin Liu, Hao-Hao Song, Lu Dong, Miao-Miao Ke, Jie Liu, Yong-Jun Liu, Ke Zhao, Ming Wang, Feng-Qing Wei, Dong-Zhi
- 机构：Shanghai Univ Med & Hlth Sci;East China Univ Sci & Technol;Huawei Safety Evaluat & Med Res Shanghai Co Ltd
- 来源：SYNTHETIC AND SYSTEMS BIOTECHNOLOGY 2022
- 关键词：Mycolicibacterium 9-OHAD Cell permeability Soybean phytosterol fbpC3 embC
- One-pot biosynthesis of 7β-hydroxyan drost-4-ene-3,17-dione from phytosterols by cofactor regeneration system in engineered mycolicibacterium neoaurum被引量：12收藏
- 作者：Zhao, Yun-Qiu Liu, Yong-Jun Ji, Wei-Ting Liu, Kun Gao, Bei Tao, Xin-Yi Zhao, Ming Wang, Feng-Qing Wei, Dong-Zhi
- 机构：East China Univ Sci & Technol
- 来源：MICROBIAL CELL FACTORIES 2022
- 关键词：7 beta-hydroxyandrost-4-ene-3,17-dione Phytosterols mP450-BM3 Nicotinamide adenine dinucleotide phosphate regeneration Mycolicibacterium
- Gemfibrozil reduces lipid accumulation in SMMC-7721 cells via the involvement of PPAR and SREBP1被引量：9收藏
- 作者：Zhang, Xiaonan Wang, Song Hu, Linlin Wang, Jian Liu, Yajing Shi, Ping
- 机构：East China Univ Sci & Technol
- 来源：EXPERIMENTAL AND THERAPEUTIC MEDICINE 2019
- 关键词：human hepatoma SMMC-7721 cells oleic acid gemfibrozil
- PEGylated graphene oxide as a nanocarrier of the disulfide prodrug of podophyllotoxin for cancer therapy被引量：9收藏
- 作者：Liu, Yajing Lv, Xiaoguang Xia, Shengli Hao, Bingjie Huang, Xiaoyu Shi, Ping
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Shanghai Univ Med & Hlth Sci;Chinese Acad Sci
- 来源：JOURNAL OF NANOPARTICLE RESEARCH 2020
- 关键词：Nanocarrier GO-PEG DCM-S-PPT GSH Tumor-bearing mice Nanomedicine
- Simultaneous detection of 5-fluorocytosine and 5-fluorouracil in human cells carrying CD/5-FC suicide gene system by using capillary zone electrophoresis被引量：9收藏
- 作者：Liu, Yajing Zhu, Pan Huang, Zhiwei Zhou, Li Shi, Ping
- 机构：East China Univ Sci & Technol;Chinese Acad Sci;Donghua Univ
- 来源：JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES 2018
- 关键词：CD/5-FC system Capillary zone electrophoresis 5-FC 5-FU Human cells
- Enhanced conversion of sterols to steroid synthons by augmenting the peptidoglycan synthesis gene pbpB in Mycobacterium neoaurum被引量：8收藏
- 作者：Sun, Wan-Ju Liu, Yong-Jun Liu, Hao-Hao Ma, Jie-De Ren, Yu-Hong Wang, Feng-Qing Wei, Dong-Zhi
- 机构：East China Univ Sci & Technol;Yantai Hosp Tradit Chinese Med
- 来源：JOURNAL OF BASIC MICROBIOLOGY 2019
- 关键词：22-hydroxy-23 24-bisnorchol-4-ene-3-one mycobacteria pbpB peptidoglycan sterols
- Trivalent Chromium Supplementation Ameliorates Oleic Acid-Induced Hepatic Steatosis in Mice被引量：8收藏
- 作者：Wang, Song Wang, Jian Liu, Yajing Li, Hui Wang, Qiao Huang, Zhiwei Liu, Wenbin Shi, Ping
- 机构：East China Univ Sci & Technol;Shanghai Res Inst Criminal Sci & Technol;Donghua Univ
- 来源：BIOLOGICAL TRACE ELEMENT RESEARCH 2019
- 关键词：Steatosis Trivalent chromium CD36 DGAT2 Inflammatory cytokines
- Original Multiplexed site-specific genome engineering in Mycolicibacterium neoaurum by Att/Int system被引量：7收藏
- 作者：Liu, Ke Lin, Gui-Hong Liu, Kun Liu, Yong-Jun Tao, Xin-Yi Gao, Bei Zhao, Ming Wei, Dong-Zhi Wang, Feng-Qing
- 机构：East China Univ Sci & Technol
- 来源：SYNTHETIC AND SYSTEMS BIOTECHNOLOGY 2022
- 关键词：Site-specific recombination Phage integrase Xer recombinases Mycolicibacterium Multi-copy integration
- Unravelling and engineering an operon involved in the side-chain degradation of sterols in Mycolicibacterium neoaurum for the production of steroid synthons被引量：7收藏
- 作者：Zhao, Yun-Qiu Liu, Yong-Jun Song, Lu Yu, Dingyan Liu, Kun Liu, Ke Gao, Bei Tao, Xin-Yi Xiong, Liang-Bin Wang, Feng-Qing Wei, Dong-Zhi
- 机构：East China Univ Sci & Technol;Shanghai Univ Med & Hlth Sci
- 来源：BIOTECHNOLOGY FOR BIOFUELS AND BIOPRODUCTS 2023
- 关键词：Mycolicibacteria HBC sub-pathway atf1 HBC operon C-22 steroid 4-HBC
- CRISPR-Cas Assisted Shotgun Mutagenesis Method for EvolutionaryGenome Engineering被引量：7收藏
- 作者：Zhao, Ming Gao, Miaomiao Xiong, Liangbin Liu, Yongjun Tao, Xinyi Gao, Bei Liu, Min Wang, Feng-Qing Wei, Dong-Zhi
- 机构：East China Univ Sci & Technol;Anhui Polytech Univ;Shanghai Univ Med & Hlth Sci
- 来源：ACS SYNTHETIC BIOLOGY 2022
- 关键词：CRISPR-mediated genome engineering whole-genome mutagenesis iterative evolution
- Photocaged prodrug under NIR light-triggering with dual-channel fluorescence: in vivo real-time tracking for precise drug delivery被引量：4收藏
- 作者：Zhiqian Guo Yaguang Ma Yajing Liu Chenxu Yan Ping Shi He Tian Wei-Hong Zhu
- 机构：Key Laboratory for Advanced Materials and Institute of Fine Chemicals;State Key Laboratory of Bioreactor Engineering
- 来源：中国科学（化学英文版） 2018
- 关键词：vivo 荧光变化 NIR 隧道 即时 交货 触发 追踪
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- Effectively enhancing cytotoxic and apoptotic effects of alpha-momorcharin by integrating a heparin-binding peptide被引量：4收藏
- 作者：Tan, Meng-Jie Cao, Xue-Wei Li, Peng-Fei Zhai, Yi-Zhou Zhou, Yu Liu, Ye-Jun Zhao, Jian Wang, Fu-Jun
- 机构：East China Univ Sci & Technol;Zhejiang Reachall Pharmaceut Co Ltd;Shanghai Univ Chinese Tradit Med
- 来源：BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY 2017
- 关键词：antitumor activity apoptosis cell-penetrating peptides heparin-binding peptide alpha-MMC-HBP
- Sequential resolution of (S) and (R)-6-fluoro-chroman-2-carboxylic acid by two esterases in turn被引量：2收藏
- 作者：Jiang, Min Liu, Yong-Jun Liu, Guo-Song Zhou, Wei Shen, Ya-Ling Gao, Bei Wang, Feng-Qing Wei, Dong-Zhi
- 机构：East China Univ Sci & Technol
- 来源：GREEN CHEMISTRY 2022
- 关键词：Cell culture - Cells - Enzymes - Stereochemistry
