成果/Result
- Salt stress induced lipid accumulation in heterotrophic culture cells of Chlorella protothecoides: Mechanisms based on the multi-level analysis of oxidative response, key enzyme activity and biochemical alteration被引量：100收藏
- 作者：Wang, Tao Ge, Haiyan Liu, Tingting Tian, Xiwei Wang, Zejian Guo, Meijin Chu, Ju Zhuang, Yingping
- 机构：E China Univ Sci & Technol
- 来源：JOURNAL OF BIOTECHNOLOGY 2016
- 关键词：Chlorella protothecoides Heterotrophic culture Lipid Microalgae ROS Salt stress
- Optimized biosynthesis of xanthan via effective valorization of orange peels using response surface methodology: A kinetic model approach被引量：73收藏
- 作者：Mohsin, Ali Zhang, Kuipu Hu, Junlang Salim-ur-Rehman Tariq, Muhammad Zaman, Waqas Qamar Khan, Imran Mahmood Zhuang, Yingping Guo, Meijin
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Univ Agr Faisalabad
- 来源：CARBOHYDRATE POLYMERS 2018
- 关键词：Xanthan gum Orange peel Fermentation Response surface methodology and kinetic analysis
- Toxicity assessment of zebrafish following exposure to CdTe QDs被引量：67收藏
- 作者：Zhang, Wei Lin, Kuangfei Miao, Youna Dong, Qiaoxiang Huang, Changjiang Wang, Huili Guo, Meijin Cui, Xinhong
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol;E China Univ Sci & Technol;Wenzhou Med Coll;E China Univ Sci & Technol
- 来源：JOURNAL OF HAZARDOUS MATERIALS 2012
- 关键词：TGA-CdTe QDs Zebrafish Developmental toxicity Behavioral toxicity
- Enhanced Biosynthesis of Chlorogenic Acid and Its Derivatives in Methyl-Jasmonate-Treated Gardenia jasminoides Cells: A Study on Metabolic and Transcriptional Responses of Cells被引量：63收藏
- 作者：Liu, Zebo Mohsin, Ali Wang, Zejian Zhu, Xiaofeng Zhuang, Yingping Cao, Liming Guo, Meijin Yin, Zhongping
- 机构： State Key Laboratory of Bioreactor Engineering; Jiangxi Key Laboratory of Natural Products and Functional Foods; Crop Breeding and Cultivation Research Institute
- 来源：Frontiers in Bioengineering and Biotechnology 2020
- 关键词：Biosynthesis - Plants (botany) - Signal transduction - Bacteriophages - Transcription
- Xanthan-Curdlan nexus for synthesizing edible food packaging films被引量：61收藏
- 作者：Mohsin, Ali Zaman, Waqas Qamar Guo, Meijin Ahmed, Waheed Khan, Imran Mahmood Niazi, Sobia Rehman, Abdur Hang, Haifeng Zhuang, Yingping
- 机构：East China Univ Sci & Technol;Natl Univ Sci & Technol NUST;Jiangnan Univ
- 来源：INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES 2020
- 关键词：Xanthangum Curdlan Blendfilms
- Advances in sustainable approaches utilizing orange peel waste to produce highly value-added bioproducts被引量：55收藏
- 作者：Mohsin, Ali Hussain, Muhammad Hammad Zaman, Waqas Qamar Mohsin, Muhammad Zubair Zhang, Junhong Liu, Zebo Tian, Xiwei Salim-Ur-Rehman Khan, Imran Mehmood Niazi, Sobia Zhuang, Yingping Guo, Meijin
- 机构：East China Univ Sci & Technol;Natl Univ Sci & Technol;Univ Agr Faisalabad;Jiangnan Univ
- 来源：CRITICAL REVIEWS IN BIOTECHNOLOGY 2022
- 关键词：Orange peel waste valorization extraction technologies fermentation approaches biorefineries bioproducts
- Production of polymalic acid and malic acid from xylose and corncob hydrolysate by a novel Aureobasidium pullulans YJ 6-11 strain被引量：51收藏
- 作者：Zou, Xiang Yang, Jing Tian, Xu Guo, Meijing Li, Zhenghua Li, Yunzheng
- 机构：Southwest Univ;Chongqing Univ;E China Univ Sci & Technol;Anhui Sealong Biotechnol Co Ltd
- 来源：PROCESS BIOCHEMISTRY 2016
- 关键词：Aureobasidium pullulans Corncob hydrolysate Fermentation Malic acid Polymalic acid Xlyose
- Engineered Bacteria-Based Living Materials for Biotherapeutic Applications被引量：51收藏
- 作者：Omer, Rabia Mohsin, Muhammad Zubair Mohsin, Ali Mushtaq, Bilal Sajid Huang, Xumeng Guo, Meijin Zhuang, Yingping Huang, Jiaofang
- 机构：East China Univ Sci & Technol;Jiangnan Univ
- 来源：FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY 2022
- 关键词：engineered living materials synthetic live therapy synthetic biology biodiagnostic biotherapeutics multiplex diseases
- Mechanistic insight for improving butenyl-spinosyn production through combined ARTP/UV mutagenesis and ribosome engineering in Saccharopolyspora pogona被引量：49收藏
- 作者：Zhao, Xueli Hussain, Muhammad Hammad Mohsin, Ali Liu, Zebo Xu, Zhixian Li, Zhanxia Guo, Weiqun Guo, Meijin
- 机构： State Key Laboratory of Bioreactor Engineering; Department of Respiratory Medicine; Academy of National Food and Strategic Reserves Administration
- 来源：Frontiers in Bioengineering and Biotechnology 2023
- 关键词：Biochemistry - Macromolecules - Mutagenesis
- Toxicological effect of MPA-CdSe QDs exposure on zebrafish embryo and larvae被引量：48收藏
- 作者：Zhang, Wei Lin, Kuangfei Sun, Xue Dong, Qiaoxiang Huang, Changjiang Wang, Huili Guo, Meijin Cui, Xinhong
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol;E China Univ Sci & Technol;Wenzhou Med Coll;E China Univ Sci & Technol
- 来源：CHEMOSPHERE 2012
- 关键词：MPA-CdSe QDs Zebrafish embryo Zebrafish larvae Developmental toxicity Behavioral toxicity
- Sustainable biosynthesis of curdlan from orange waste by using Alcaligenes faecalis: A systematically modeled approach被引量：48收藏
- 作者：Mohsin, Ali Sun, Jingyun Khan, Imran Mahmood Hang, Haifeng Tariq, Muhammad Tian, Xiwei Ahmed, Waqas Niazi, Sobia Zhuang, Yingping Chu, Ju Mohsin, Muhammad Zubair Salim-ur-Rehman Guo, Meijin
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Jiangnan Univ;Univ Agr Faisalabad;Univ Agr Faisalabad
- 来源：CARBOHYDRATE POLYMERS 2019
- 关键词：Sustainable biosynthesis Orange peels Kinetics Curdlan Batch culture fermentation
- Acute and chronic toxic effects of bisphenol a on Chlorella pyrenoidosa and Scenedesmus obliquus被引量：48收藏
- 作者：Zhang, Wei Xiong, Bang Sun, Wen-Fang An, Shuai Lin, Kuang-Fei Guo, Mei-Jin Cui, Xin-Hong
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol;E China Univ Sci & Technol;E China Univ Sci & Technol;Shanghai Inst Landscape Gardening
- 来源：ENVIRONMENTAL TOXICOLOGY 2014
- 关键词：acute toxicity Scenedesmus obliquus BPA Chlorella pyrenoidosa chronic toxicity
- Understanding the effect of forEIgn gene dosage on the physiology of Pichia pastoris by transcriptional analysis of key genes被引量：47收藏
- 作者：Zhu, Taicheng Guo, Meijin Zhuang, Yingping Chu, Ju Zhang, Siliang
- 机构：E China Univ Sci & Technol;Chinese Acad Sci
- 来源：APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 2011
- 关键词：Gene dosage Pichia pastoris Methanol metabolism Cell physiology mRNA quantitative analysis
- Global regulator BldA regulates morphological differentiation and lincomycin production in Streptomyces lincolnensis被引量：46收藏
- 作者：Hou, Bingbing Tao, Liyuan Zhu, Xiaoyu Wu, Wei Guo, Meijin Ye, Jiang Wu, Haizhen Zhang, Huizhan
- 机构： State Key Laboratory of Bioreactor Engineering; Department of Applied Biology
- 来源：Applied Microbiology and Biotechnology 2018
- 关键词：Encoding (symbols) - Amino acids - Bacteria - Metabolism
- A two-stage fed-batch heterotrophic culture of Chlorella protothecoides that combined nitrogen depletion with hyperosmotic stress strategy enhanced lipid yield and productivity被引量：45收藏
- 作者：Wang, Tao Tian, Xiwei Liu, Tingting Wang, Zejian Guan, Wenyan Guo, Meijin Chu, Ju Zhuang, Yingping
- 机构：East China Univ Sci & Technol
- 来源：PROCESS BIOCHEMISTRY 2017
- 关键词：Microalgae Lipid Glucose inhibition Hyperosmotic stress Two-stage fed-batch culture
- Effects of Pb(II) exposure on Chlorella protothecoides and Chlorella vulgaris growth, malondialdehyde, and photosynthesis-related gene transcription被引量：38收藏
- 作者：Xiong, Bang Zhang, Wei Chen, Lin Lin, Kuang-Fei Guo, Mei-Jin Wang, Wei-Liang Cui, Xin-Hong Bi, Hua-Song Wang, Bin
- 机构： State Env. Protection Key Lab. of Env. Risk Ass. and Control on Chemical Process; School of Resource and Environmental Engineering; The State Key Laboratory of Bioreactor Engineering; Shanghai Institute of Landscape Gardening
- 来源：Environmental Toxicology 2020
- 关键词：Polymerase chain reaction - Aldehydes - Aquatic organisms - Plants (botany) - Transcription - Lead compounds
- Dynamic Metabolism Mechanism of Halomonas Elongata Dsm 2581t Response to Nacl Shock Stress: An Effective Technology for Enhancing Ectoine Biosynthesis被引量：36收藏
- 作者：Yu, Junxiong Zhang, Yue Wang, Jing Liu, Yuxuan Mohisn, Ali Liu, Hao Zheng, Yanning Xing, Jianmin Zhuang, Yingping Guo, Meijin Wang, Zejian
- 机构： State Key Laboratory of Bioreactor Engineering; Department of Chemical Engineering for Energy Resources; State Key Laboratory of Microbial Resources; College of Chemical Engineering
- 来源：SSRN 2023
- 关键词：Biochemistry - Biosynthesis - Industrial research - Industrial water treatment - Metabolism - Metabolites - Wastewater treatment
- Real-time and on-line parallel detection of key fermentation process parameters by near-infrared spectroscopy in different environments被引量：34收藏
- 作者：Chen, Yang Chen, Lingli Guo, Meijin Li, Xu Liu, Jinsong Liu, Xiaofeng Chen, Zhongbing Tian, Xiaojun Zheng, Haoyue Tian, Xiwei Chu, Ju Zhuang, Yingping
- 机构： State Key Laboratory of Bioreactor Engineering; SDIC Biotech Investment Co. Ltd.; Zhejiang Biok Co.Ltd; East China University of Science and Technology; State Key Laboratory of Bioreactor Engineering
- 来源：Research Square 2021
- 关键词：Fermentation - Infrared devices - Lactic acid - Least squares approximations - Mean square error - Process control - Sodium - Substrates
- Molecular cloning and functional characterization of an ATP-binding cassette transporter OtrC from Streptomyces rimosus被引量：34收藏
- 作者：Yu, Lan Yan, Xiangyun Wang, Long Chu, Ju Zhuang, Yingping Zhang, Siliang Guo, Meijin
- 机构： State Key Laboratory of Bioreactor Engineering; School of Life and Science
- 来源：BMC Biotechnology 2012
- 关键词：Clone cells - Cloning - Escherichia coli
- Production and purification of a novel thermostable phytase by Pichia pastoris FPHY34被引量：32收藏
- 作者：Guo, Mei-Jin Zhuang, Ying-Ping Chu, Ju Zhang, Si-Liang Xiong, Ai-Sheng Peng, Ri-He Yao, Quan-Hong
- 机构： State Key Laboratory of Bioreactor Engineering; Department of Biotechnology; Research Centre for Agro-Biotechnology
- 来源：Process Biochemistry 2007
- 关键词：Cell growth - DNA - Fermenters - Genetic engineering - Methanol - Microfiltration - Thermodynamic stability
- Recent Advances of Magnetic Nanomaterials for Bioimaging, Drug Delivery, and Cell Therapy被引量：31收藏
- 作者：Mohsin, Ali Hussain, Muhammad Hammad Mohsin, Muhammad Zubair Zaman, Waqas Qamar Aslam, Muhammad Shahbaz Shan, Ali Dai, Yichen Khan, Imran Mahmood Niazi, Sobia Zhuang, Yingping Guo, Meijin
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Jiangnan Univ;Univ Punjab;Natl Univ Sci & Technol NUST
- 来源：ACS APPLIED NANO MATERIALS 2022
- 关键词：magnetic nanoparticles mesenchymal stem cells regeneration drug delivery cancer cells target killing
- Improved oxytetracycline production in Streptomyces rimosus M4018 by metabolic engineering of the G6PDH gene in the pentose phosphate pathway被引量：31收藏
- 作者：Tang, Zhenyu Xiao, Ciying Zhuang, Yingping Chu, Ju Zhang, Siliang Herron, Paul R. Hunter, Iain S. Guo, Meijin
- 机构： State Key Laboratory of Bioreactor Engineering; Strathclyde Institute of Pharmacy and Biomedical Sciences
- 来源：Enzyme and Microbial Technology 2011
- 关键词：Biochemistry - Gene expression - Metabolic engineering - Carbon - Ketones - Bacteria - Biomolecules - Biosynthesis - Enzymes - Glucose - Physiology - Metabolites - Antibiotics
- Combinatorial Effect of ARTP Mutagenesis and Ribosome Engineering on an Industrial Strain of Streptomyces albus S12 for Enhanced Biosynthesis of Salinomycin被引量：31收藏
- 作者：Zhang, Kuipu Mohsin, Ali Dai, Yichen Chen, Zhongbing Zhuang, Yingping Chu, Ju Guo, Meijin
- 机构：East China Univ Sci & Technol;Zhejiang Biok Biol Co Ltd
- 来源：FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY 2019
- 关键词：agar block diffusion method atmospheric and room temperature plasma ribosome engineering transcriptome analysis salinomycin glyoxylate metabolism
- Oxytetracycline biosynthesis improvement in Streptomyces rimosus following duplication of minimal PKS genes被引量：30收藏
- 作者：Yu, Lan Cao, Nan Wang, Long Xiao, Ciying Guo, Meijin Chu, Ju Zhuang, Yingping Zhang, Siliang
- 机构： State Key Laboratory of Bioreactor Engineering; School of Life and Science
- 来源：Enzyme and Microbial Technology 2012
- 关键词：Bacteria - Growth kinetics - Ketones - Cell growth - Plants (botany) - Polymerase chain reaction - Biochemistry - Morphology - Transcription
- Independent component analysis-based non-Gaussian process monitoring with preselecting optimal components and support vector data description被引量：29收藏
- 作者：Jiang, Qingchao Yan, Xuefeng Lv, Zhaomin Guo, Meijin
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol
- 来源：INTERNATIONAL JOURNAL OF PRODUCTION RESEARCH 2014
- 关键词：independent component analysis multivariate statistics process monitoring support vector data description optimal component selection
- Qualitative improvement of camel milk date yoghurt by addition of biosynthesized xanthan from orange waste被引量：29收藏
- 作者：Mohsin, Ali Ni, Hui Luo, Yanxia Wei, Yanlong Tian, Xiwei Guan, Wenyan Ali, Muhammad Khan, Imran Mahmood Niazi, Sobia Rehman, Salim-ur Zhuang, Yingping Guo, Meijin
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Jiangnan Univ;Univ Agr Faisalabad;Univ Calif
- 来源：LWT-FOOD SCIENCE AND TECHNOLOGY 2019
- 关键词：Camel milk Biosynthesized xanthan Date paste Yoghurt Rheology
- CO2(aq) concentration-dependent CO2 fixation via carboxylation by decarboxylase被引量：28收藏
- 作者：Fan, Yan Feng, Jianqiang Yang, Miao Tan, Xin Fan, Hongjun Guo, Meijin Wang, Binju Xue, Song
- 机构：Chinese Acad Sci;Univ Chinese Acad Sci;Xiamen Univ;Natl Ctr Bioengn & Technol;East China Univ Sci & Technol
- 来源：GREEN CHEMISTRY 2021
- 关键词：Carbon - Carboxylation - Phenols
- 基于细胞周期调控的 CHO 细胞强化流加补料工艺提高重组抗体表达效率被引量：27收藏
- 作者：Xiao, Shang Yin, Pei Zhou, Junqi Li, Weifeng Molish, Ali Guo, Meijin
- 机构： State Key laboratory of Bioreactor Engineering; Shanghai TopAlliance Biosciences Co.
- 来源：[1] State Key laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, 200237, China; [2] Shanghai TopAlliance Biosciences Co., Ltd., Shanghai, 201318, China 2026
- RQ feedback control for simultaneous improvement of GSH yield and GSH content in Saccharomyces cerevisiae T65被引量：27收藏
- 作者：Xiong, Zhi-Qiang Guo, Mei-Jin Guo, Yuan-Xin Chu, Ju Zhuang, Ying-Ping Wang, Nam Sun Zhang, Si-Liang
- 机构： State Key Laboratory of Bioreactor Engineering; Department of Chemical and Biomolecular Engineering
- 来源：Enzyme and Microbial Technology 2010
- 关键词：Oxygen - Proportional control systems - Two term control systems - Glucose - Peptides - Yeast - Ethanol - Carbon dioxide - Productivity
- Enhanced production of biosynthesized lycopene via heterogenous MVA pathway based on chromosomal multiple position integration strategy plus plasmid systems in Escherichia coli被引量：27收藏
- 作者：Wei, Yanlong Mohsin, Ali Hong, Qi Guo, Meijin Fang, Hongqing
- 机构：East China Univ Sci & Technol;Anhui Univ;Acad Mil Med Sci
- 来源：BIORESOURCE TECHNOLOGY 2018
- 关键词：Lycopene biosynthesis Heterogenous MVA pathway Chromosomal multiple position integration strategy Plasmid system Escherichia coli
