成果/Result
- In Vivo and in Situ Tracking Cancer Chemotherapy by Highly Photostable NIR Fluorescent Theranostic Prodrug被引量：496收藏
- 作者：Wu, Xumeng Sun, Xuanrong Guo, Zhiqian Tang, Jianbin Shen, Youqing James, Tony D. Tian, He Zhu, Weihong
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol;Zhejiang Univ;Zhejiang Univ;Univ Bath
- 来源：JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 2014
- 关键词：Controlled drug delivery - Chemotherapy - Nanoparticles - Oncology - Sulfur compounds - Fluorophores - Targeted drug delivery - Drug products - Diseases - Infrared devices
- Real-Time Tracking and In Vivo Visualization of β-Galactosidase Activity in Colorectal Tumor with a Ratiometric Near-Infrared Fluorescent Probe被引量：451收藏
- 作者：Gu, Kaizhi Xu, Yisheng Li, Hui Guo, Zhiqian Zhu, Shaojia Zhu, Shiqin Shi, Ping James, Tony D. Tian, He Zhu, Wei-Hong
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol;E China Univ Sci & Technol;E China Univ Sci & Technol;Shanghai Jiao Tong Univ
- 来源：JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 2016
- 关键词：Enzyme activity - Probes - Infrared devices - Diseases - Fluorescence - Molecular biology - Physiological models - Physiology - Tumors
- A highly selective ratiometric near-infrared fluorescent cyanine sensor for cystEIne with remarkable shift and its application in bioimaging被引量：414收藏
- 作者：Guo, Zhiqian Nam, SeongWon Park, Sungsu Yoon, Juyoung
- 机构：Ewha Womans Univ;Ewha Womans Univ;E China Univ Sci & Technol;E China Univ Sci & Technol
- 来源：CHEMICAL SCIENCE 2012
- 关键词：Amino acids - Emission spectroscopy - Cancer cells - Infrared devices - Ketones
- Far-Red and Near-IR AIE-Active Fluorescent Organic Nanoprobes with Enhanced Tumor-Targeting Efficacy: Shape-Specific Effects被引量：383收藏
- 作者：Shao, Andong Xie, Yongshu Zhu, Shaojia Guo, Zhiqian Zhu, Shiqin Guo, Jin Shi, Ping James, Tony D. Tian, He Zhu, Wei-Hong
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol;PerkinElmer Instruments Shanghai Co;Univ Bath
- 来源：ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 2015
- 关键词：aggregation-induced emission fluorescent probes morphology effects near infrared tumor targeting
- A dual-response BODIPY-based fluorescent probe for the discrimination of glutathione from cystEIn and homocystEIn被引量：264收藏
- 作者：Wang, Feiyi Zhou, Li Zhao, Chunchang Wang, Rui Fei, Qiang Luo, Sihang Guo, Zhiqian Tian, He Zhu, Wei-Hong
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol;E China Univ Sci & Technol
- 来源：CHEMICAL SCIENCE 2015
- 关键词：Cyclization - Probes - Covalent bonds - Fluorescence imaging - Peptides - Sulfur compounds
- A fluorophore capable of crossword puzzles and logic memory被引量：240收藏
- 作者：Guo, Zhiqian Zhu, Weihong Shen, Liangjun Tian, He
- 机构：E China Univ Sci & Technol
- 来源：ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 2007
- 关键词：copper fluorescent probes logic memory mercury molecular devices
- High-Performance Quinoline-Malononitrile Core as a Building Block for the Diversity-Oriented Synthesis of AIEgens被引量：196收藏
- 作者：Guo, Zhiqian Yan, Chenxu Zhu, Wei-Hong
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 2020
- 关键词：aggregation-induced emission bioimaging fluorescence probes near-infrared quinoline-malononitrile
- Self-Assembly Solid-State Enhanced Red Emission of Quinolinemalononitrile: Optical Waveguides and Stimuli Response被引量：190收藏
- 作者：Shi, Chuanxing Guo, Zhiqian Yan, Yongli Zhu, Shiqin Xie, Yongshu Zhao, Yong Sheng Zhu, Weihong Tian, He
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol;Chinese Acad Sci;Chinese Acad Sci
- 来源：ACS APPLIED MATERIALS & INTERFACES 2013
- 关键词：solid-state fluorescence self-assembly crystal structures optical waveguides stimuli-response cell imaging
- Circularly Polarized Fluorescence Resonance Energy Transfer (C-FRET) for Efficient Chirality Transmission within an Intermolecular System被引量：164收藏
- 作者：Wu, Yue Yan, Chenxu Li, Xin-Shun You, Li Hong Yu, Zhen-Qiang Wu, Xiaofeng Zheng, Zhigang Liu, Guofeng Guo, Zhiqian Tian, He Zhu, Wei-Hong
- 机构：Shenzhen Univ;East China Univ Sci & Technol;East China Univ Sci & Technol;Univ Liverpool;Univ Liverpool
- 来源：ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 2021
- 关键词：aggregation-induced emission circularly polarized luminescence fluorescence FRET self-assembly
- An enzyme-activatable probe liberating AIEgens: on-site sensing and long-term tracking of -galactosidase in ovarian cancer cells被引量：161收藏
- 作者：Gu, Kaizhi Qiu, Wanshan Guo, Zhiqian Yan, Chenxu Zhu, Shiqin Yao, Defan Shi, Ping Tian, He Zhu, Wei-Hong
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Fudan Univ;East China Univ Sci & Technol
- 来源：CHEMICAL SCIENCE 2019
- 关键词：Hydrophobicity - Cytology - Cells - Diseases - Fluorescence - Cancer cells - Diagnosis - Enzymes
- A cyanine-based fluorescent sensor for detecting endogenous zinc ions in live cells and organisms被引量：157收藏
- 作者：Guo, Zhiqian Kim, Gun-Hee Shin, Injae Yoon, Juyoung
- 机构：Ewha Womans Univ;Ewha Womans Univ;E China Univ Sci & Technol;E China Univ Sci & Technol;Yonsei Univ
- 来源：BIOMATERIALS 2012
- 关键词：Zinc Near-infrared Cyanine Zebrafish Sensor
- Insight into aggregation-induced emission characteristics of red-emissive quinoline-malononitrile by cell tracking and real-time trypsin detection被引量：156收藏
- 作者：Shao, Andong Guo, Zhiqian Zhu, Shaojia Zhu, Shiqin Shi, Ping Tian, He Zhu, Weihong
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol;E China Univ Sci & Technol
- 来源：CHEMICAL SCIENCE 2014
- 关键词：High resolution transmission electron microscopy - Solutions - Dynamic light scattering - Hydrophilicity
- A molecular design strategy toward enzyme-activated probes with near-infrared I and II fluorescence for targeted cancer imaging被引量：147收藏
- 作者：Wang, Rongchen Chen, Jian Gao, Jie Chen, Ji-An Xu, Ge Zhu, Tianli Gu, Xianfeng Guo, Zhiqian Zhu, Wei-Hong Zhao, Chunchang
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Fudan Univ
- 来源：CHEMICAL SCIENCE 2019
- 关键词：Enzymes - Dies - Medical imaging - Diseases - Optical properties - Fluorescence imaging - Infrared devices
- Enabling Light Work in Helical Self-Assembly for Dynamic Amplification of Chirality with Photoreversibility被引量：147收藏
- 作者：Cai, Yunsong Guo, Zhiqian Chen, Jianmei Li, Wenlong Zhong, Liubiao Gao, Ya Jiang, Lin Chi, Lifeng Tian, He Zhu, Wei-Hong
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol;Soochow Univ;Univ Munster;Univ Munster
- 来源：JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 2016
- 关键词：Hydrogen bonds - Chirality - Light
- Dual-channel NIR activatable theranostic prodrug for in vivo spatiotemporal tracking thiol-triggered chemotherapy被引量：139收藏
- 作者：Ye, Mingzhou Wang, Xiaohang Tang, Jianbin Guo, Zhiqian Shen, Youqing Tian, He Zhu, Wei-Hong
- 机构：Zhejiang Univ;Zhejiang Univ;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：CHEMICAL SCIENCE 2016
- 关键词：Biological organs - Controlled drug delivery - Infrared devices - Targeted drug delivery - Fluorescence - Sulfur compounds - Covalent bonds - Bioimaging - Chemotherapy
- Development of a Small Molecule Probe Capable of Discriminating CystEIne, HomocystEIne, and Glutathione with Three Distinct Turn-On Fluorescent Outputs被引量：133收藏
- 作者：Wang, Feiyi Guo, Zhiqian Li, Xia Li, Xiuai Zhao, Chunchang
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol
- 来源：CHEMISTRY-A EUROPEAN JOURNAL 2014
- 关键词：biosensors fluorescent probes selectivity sensors thiols
- A Sequential Dual-Lock Strategy for Photoactivatable Chemiluminescent Probes Enabling Bright Duplex Optical Imaging被引量：120收藏
- 作者：Zhang, Yutao Yan, Chenxu Wang, Chao Guo, Zhiqian Liu, Xiaogang Zhu, Wei-Hong
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Singapore Univ Technol & Design
- 来源：ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 2020
- 关键词：aggregation-induced emission chemiluminescent probes dual-mode bioimaging fluorescence probes sequential dual-lock
- Enzyme-activatable fluorescent probes for β-galactosidase: from design to biological applications被引量：113收藏
- 作者：Yao, Yongkang Zhang, Yutao Yan, Chenxu Zhu, Wei-Hong Guo, Zhiqian
- 机构：East China Univ Sci & Technol
- 来源：CHEMICAL SCIENCE 2021
- 关键词：Enzymes - Probes - Diseases
- High-Fidelity Trapping of Spatial-Temporal Mitochondria with Rational Design of Aggregation-Induced Emission Probes被引量：101收藏
- 作者：Zhang, Jie Wang, Qi Guo, Zhiqian Zhang, Shaoze Yan, Chenxu Tian, He Zhu, Wei-Hong
- 机构：East China Univ Sci & Technol
- 来源：ADVANCED FUNCTIONAL MATERIALS 2019
- 关键词：aggregation-induced emission high-fidelity trapping image-guided therapy mitochondrial imaging "off-on" fluorescence
- Constructing NIR silica-cyanine hybrid nanocomposite for bioimaging in vivo: A breakthrough in photo-stability and bright fluorescence with large Stokes shift被引量：96收藏
- 作者：Wu, Xumeng Chang, Shu Sun, Xuanrong Guo, Zhiqian Li, Yongsheng Tang, Jianbin Shen, Youqing Shi, Jianlin Tian, He Zhu, Weihong
- 机构： Shanghai Key Laboratory of Functional Materials Chemistry; Key Laboratory for Ultrafine Materials of Ministry of Education; Department of Chemical and Biological Engineering
- 来源：Chemical Science 2013
- 关键词：Infrared devices - Chemical stability - Silica nanoparticles - Diagnosis - Fluorescence - Image enhancement - Self assembly - Solutions - Block copolymers - Chromophores - Tumors - Hydrophilicity - Shells (structures)
- In Situ Ratiometric Quantitative Tracing of Intracellular Leucine Aminopeptidase Activity via an Activatable Near-Infrared Fluorescent. Probe被引量：87收藏
- 作者：Gu, Kaizhi Liu, Yajing Guo, Zhiqian Lian, Cheng Yan, Chenxu Shi, Ping Tian, He Zhu, Wei-Hong
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;Dalian Univ Technol
- 来源：ACS APPLIED MATERIALS & INTERFACES 2016
- 关键词：near-infrared fluorescent probe ratiometric in situ leucine aminopeptidase
- A sequence-activated AND logic dual-channel fluorescent probe for tracking programmable drug release被引量：85收藏
- 作者：Yan, Chenxu Guo, Zhiqian Liu, Yajing Shi, Ping Tian, He Zhu, Wei-Hong
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：CHEMICAL SCIENCE 2018
- 关键词：Infrared devices - Controlled drug delivery - Fluorescence - Computer circuits - Diagnosis - Tumors - Biomarkers - Targeted drug delivery
- Molecularly precise self-assembly of theranostic nanoprobes within a single-molecular framework for in vivo tracking of tumor-specific chemotherapy被引量：84收藏
- 作者：Yan, Chenxu Guo, Zhiqian Shen, Yanyan Chen, Yi Tian, He Zhu, Wei-Hong
- 机构：East China Univ Sci & Technol;Chinese Acad Sci
- 来源：CHEMICAL SCIENCE 2018
- 关键词：Cancer cells - Controlled drug delivery - Diseases - Chemotherapy - Mammals - Self assembly - Drug products - Hydrophilicity - Micelles - Coenzymes - Lanthanum compounds - Sulfur compounds - Targeted drug delivery - Critical micelle concentration - Infrared devices
- Activatable near-infrared emission-guided on-demand administration of photodynamic anticancer therapy with a theranostic nanoprobe被引量：83收藏
- 作者：Wang, Rongchen Dong, Kaikai Xu, Ge Shi, Ben Zhu, Tianli Shi, Ping Guo, Zhiqian Zhu, Wei-Hong Zhao, Chunchang
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：CHEMICAL SCIENCE 2019
- 关键词：Diseases - Photodynamic therapy - Diagnosis - Infrared devices
- Near-infrared cell-permeable Hg2+-selective ratiometric fluorescent chemodosimeters and fast indicator paper for MeHG+ based on tricarbocyanines被引量：80收藏
- 作者：Guo, Zhiqian Zhu, Weihong Zhu, Mingming Wu, Xumeng Tian, He
- 机构： Key Laboratory for Advanced Materials; Department of Gastroenterology
- 来源：Chemistry - A European Journal 2010
- 关键词：Dosimetry - Metal ions - Thioureas - Mercury compounds - Emission spectroscopy - Mercury (metal) - Infrared devices
- AND-Logic Based Fluorescent Probe for Selective Detection of Lysosomal Bisulfite in Living Cells被引量：74收藏
- 作者：Li, Ji-Zhen Sun, Yi-Hang Wang, Cheng-Yun Guo, Zhi-Qan Shen, Yong-Jia Zhu, Wei-Hong
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：ANALYTICAL CHEMISTRY 2019
- 关键词：Probes - Sulfur dioxide - Biomarkers - Alkalinity - Computer circuits - Biocompatibility - Cytology - Fluorescence
- Long wavelength AIEgen of quinoline-malononitrile被引量：74收藏
- 作者：Guo, Zhiqian Shao, Andong Zhu, Wei-Hong
- 机构：E China Univ Sci & Technol; E China Univ Sci & Technol
- 来源：JOURNAL OF MATERIALS CHEMISTRY C 2016
- 关键词：Infrared devices
- Spatio-Temporally Reporting Dose-Dependent Chemotherapy via Uniting Dual-Modal MRI/NIR Imaging被引量：71收藏
- 作者：Ma, Yiyu Yan, Chenxu Guo, Zhiqian Tan, Guang Niu, Dechao Li, Yongsheng Zhu, Wei-Hong
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 2020
- 关键词：assembly nanotheranostics chemodynamic therapy fluorescent probes magnetic resonance imaging near-infrared dual-channel
- Multiple logic fluorescent thermometer system based on N-isopropyl- methacrylamide copolymer bearing dicyanomethylene-4H-pyran moiety被引量：68收藏
- 作者：Guo, Zhiqian Zhu, Weihong Xiong, Yuyan Tian, He
- 机构： Key Laboratory for Advanced Materials
- 来源：Macromolecules 2009
- 关键词：Computer circuits - Ions - Logic gates - Fluorescence quenching - Solutions
- GSH-Activated NIR Fluorescent Prodrug for Podophyllotoxin Delivery被引量：68收藏
- 作者：Liu, Yajing Zhu, Shaojia Gu, Kaizhi Guo, Zhiqian Huang, Xiaoyu Wang, Mingwei Amin, Hesham M. Zhu, Weihong Shi, Ping
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Chinese Acad Sci;Fudan Univ;Univ Texas MD Anderson Canc Ctr
- 来源：ACS APPLIED MATERIALS & INTERFACES 2017
- 关键词：PPT prodrug NIR fluorescent reporter DCM-S-PPT mPEG-DSPE
