成果/Result
- Feature-matching Pattern-based Support Vector Machines for Robust Peptide Mass Fingerprinting被引量：79收藏
- 作者：Li, Youyuan Hao, Pei Zhang, Siliang Li, Yixue
- 机构：E China Univ Sci & Technol;Shanghai Ctr Bioinformat Technol
- 来源：MOLECULAR & CELLULAR PROTEOMICS 2011
- Synergistic Combination of Bioactive Hydroxyapatite Nanoparticles and the Chemotherapeutic Doxorubicin to Overcome Tumor Multidrug Resistance被引量：62收藏
- 作者：Dong, Xiulin Sun, Yi Li, Yuanyuan Ma, Xiaoyu Zhang, Shuiquan Yuan, Yuan Kohn, Joachim Liu, Changsheng Qian, Jiangchao
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Rutgers State Univ
- 来源：SMALL 2021
- 关键词：anti‐ tumor activity bioactivity hydroxyapatite nanoparticles mitochondrial Ca (2+) overload multidrug resistance reversal
- In Vivo Visualization of γ-Glutamyl Transpeptidase Activity with an Activatable Self-Immobilizing Near-Infrared Probe被引量：56收藏
- 作者：Li, Yuyao Xue, Chenghong Fang, Zhijun Xu, Weipan Xie, Hexin
- 机构：East China Univ Sci & Technol
- 来源：ANALYTICAL CHEMISTRY 2020
- 关键词：Mammals - Quinone - Enzyme activity - Probes - Cytology - Infrared devices
- A self-immobilizing near-infrared fluorogenic probe for sensitive imaging of extracellular enzyme activity in vivo被引量：54收藏
- 作者：Li, Yuyao Song, Heng Xue, Chenghong Fang, Zhijun Xiong, Liqin Xie, Hexin
- 机构：East China Univ Sci & Technol;Shanghai Jiao Tong Univ
- 来源：CHEMICAL SCIENCE 2020
- 关键词：Infrared devices - Quinone - Enzyme activity - Probes
- High-yield porphyrin production through metabolic engineering and biocatalysis被引量：34收藏
- 作者：Chen, Haihong Wang, Yaohong Wang, Weishan Cao, Ting Zhang, Lu Wang, Zhengduo Chi, Xuran Shi, Tong Wang, Huangwei He, Xinwei Liang, Mindong Yang, Mengxue Jiang, Wenyi Lv, Dongyuan Yu, Jiaming Zhu, Guoliang Xie, Yongtao Gao, Bei Wang, Xinye Liu, Xueting Li, Youyuan Ouyang, Limin Zhang, Jingyu Liu, Huimin Li, Zilong Tong, Yaojun Xia, Xuekui Tan, Gao-Yi Zhang, Lixin
- 机构：East China Univ Sci & Technol;Chinese Acad Sci;Shanghai Jiao Tong Univ;Qilu Univ Technol
- 来源：NATURE BIOTECHNOLOGY 2025
- 关键词：Catalysis - Diagnosis - Fermentation - Medical applications - Metabolic engineering
- CqToll participates in antiviral response against white spot syndrome virus via induction of anti-lipopolysaccharide factor in red claw crayfish Cherax quadricarinatus被引量：32收藏
- 作者：Li, Yan-yao Chen, Xiao-xiao Lin, Feng-yu Chen, Qiu-fan Ma, Xing-yuan Liu, Hai-peng
- 机构：Xiamen Univ;East China Univ Sci & Technol
- 来源：DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY 2017
- 关键词：Toll receptor Cherax quadricarinatus White spot syndrome virus Anti-lipopolysacchride factor
- Enzyme-Activatable Near-Infrared Photosensitizer with High Enrichment in Tumor Cells Based on a Multi-Effect Design被引量：27收藏
- 作者：Li, Yuyao Zhang, Chaoying Wu, Qingyi Peng, Yan Ding, Yiru Zhang, Zhengwei Xu, Xiaoyong Xie, Hexin
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Fudan Univ;Fudan Univ
- 来源：ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 2024
- 关键词：Enzyme-Activatable Fluorescence Probe Photosensitizer Quinone Methide Tumor
- Genome-scale modeling forBacillus coagulansto understand the metabolic characteristics被引量：27收藏
- 作者：Chen, Yu Sun, Yan Liu, Zhihao Dong, Fengqing Li, Yuanyuan Wang, Yonghong
- 机构：East China Univ Sci & Technol;Chalmers Univ Technol
- 来源：BIOTECHNOLOGY AND BIOENGINEERING 2020
- 关键词：Bacillus coagulans chemostat constraint-based model lactic acid fermentation metabolic switch
- Metabolic engineering Corynebacterium glutamicum to produce triacylglycerols被引量：25收藏
- 作者：Plassmeier, Jens Li, Youyuan Rueckert, Christian Sinskey, Anthony J.
- 机构：MIT;E China Univ Sci & Technol;MIT
- 来源：METABOLIC ENGINEERING 2016
- 关键词：Corynebacterium glutamicum Metabolic engineering TAG biosynthesis Triacylglycerol Microbial lipids
- Controlled synthesis and transformation of nano-hydroxyapatite with tailored morphologies for biomedical applications被引量：25收藏
- 作者：Ma, Xiaoyu Li, Yuanyuan Wang, Chengwei Sun, Yi Ma, Yifan Dong, Xiuling Qian, Jiangchao Yuan, Yuan Liu, Changsheng
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：JOURNAL OF MATERIALS CHEMISTRY B 2017
- 关键词：Microemulsions - Hydroxyapatite - Nanocomposites - Medical applications
- Phosphorylation of uridine and cytidine by uridine-cytidine kinase被引量：23收藏
- 作者：Qian, Yahui Ding, Qingbao Li, Yanyu Zou, Zhi Yan, Bingkun Ou, Ling
- 机构：E China Univ Sci & Technol
- 来源：JOURNAL OF BIOTECHNOLOGY 2014
- 关键词：Uridine 5 '-monophosphate Cytidine 5 '-monophosphate Uridine-cytidine kinase Acetate kinase GTP-regeneration
- Metabolic profiling and flux distributions reveal a key role of acetyl-CoA in sophorolipid synthesis by Candida bombicola被引量：21收藏
- 作者：Yang, Linbing Li, Youyuan Zhang, Xinkai Liu, Ting Chen, Jun Wei, Liujing Hua, Qiang
- 机构：East China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol
- 来源：BIOCHEMICAL ENGINEERING JOURNAL 2019
- 关键词：Sophorolipid Metabolic flux Metabolic profile Acetyl-CoA Candida bombicola Biosurfactant
- Time-Resolved Transcriptome Analysis of Bacillus subtilis Responding to Valine, Glutamate, and Glutamine被引量：18收藏
- 作者：Ye, Bang-Ce Zhang, Yan Yu, Hui Yu, Wen-Bang Liu, Bao-Hong Yin, Bin-Cheng Yin, Chun-Yun Li, Yuan-Yuan Chu, Ju Zhang, Si-Liang
- 机构：
- 来源：PLOS ONE 2009
- Highly Efficient Multiple-Labeling Probes for the Visualization of Enzyme Activities被引量：17收藏
- 作者：Song, Heng Li, Yuyao Chen, Yefeng Xue, Chenghong Xie, Hexin
- 机构：East China Univ Sci & Technol
- 来源：CHEMISTRY-A EUROPEAN JOURNAL 2019
- 关键词：alkaline phosphatase enzyme activity imaging immobilization quinone methide
- One-pot process of 2'-deoxyguanylic acid catalyzed by a multi-enzyme system被引量：12收藏
- 作者：Li, Yanyu Ding, Qingbao Ou, Ling Qian, Yahui Zhang, Jiao
- 机构：E China Univ Sci & Technol
- 来源：BIOTECHNOLOGY AND BIOPROCESS ENGINEERING 2015
- 关键词：2 '-deoxyguanylic acid N-deoxyribosyltransferase purine nucleoside phosphorylase deoxyguanosine kinase acetate kinase
- The Impact of Heat-Moisture Treatment on Physicochemical Properties and Retrogradation Behavior of Sweet Potato Starch被引量：12收藏
- 作者：Li, Yaoyao Liu, Shaowei Liu, Xue Tang, Xiaozhi Zhang, Jian
- 机构：East China Univ Sci & Technol;China Agr Univ;Coll Food Sci & Engn;Chinese Acad Sci;Shandong Marine Resource & Environm Res Inst
- 来源：INTERNATIONAL JOURNAL OF FOOD ENGINEERING 2017
- 关键词：sweet potato starch heat-moisture treatment physicochemical properties digestibility retrogradation
- Direct proteomic mapping of Streptomyces avermitilis wild and industrial strain and insights into avermectin production被引量：12收藏
- 作者：Yin, Peng Li, You-Yuan Zhou, Jin Wang, Yong-Hong Zhang, Si-Liang Ye, Bang-Ce Ge, Wei-Feng Xia, Yue-Lan
- 机构：E China Univ Sci & Technol
- 来源：JOURNAL OF PROTEOMICS 2013
- 关键词：Streptomyces avermitilis Proteomics Regulatory mechanism Avermectin production
- High-contrast and real-time visualization of membrane proteins in live cells with malachite green-based fluorogenic probes被引量：10收藏
- 作者：Chen, Yefeng Xue, Chenghong Wang, Jie Xu, Minqiu Li, Yuyao Ding, Yiru Song, Heng Xu, Weipan Xie, Hexin
- 机构：East China Univ Sci & Technol
- 来源：CHINESE CHEMICAL LETTERS 2022
- 关键词：Cellular imaging Fluorogenic probe Environment-sensitive fluorophore Alkaline phosphatase Integrin
- CRISPR/Cas9-based toolkit for rapid marker recycling and combinatorial libraries in Komagataella phaffii被引量：10收藏
- 作者：Zhou, Wei Li, Yuanyi Liu, Guosong Qin, Weichuang Wei, Dongzhi Wang, Fengqing Gao, Bei
- 机构：East China Univ Sci & Technol
- 来源：APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 2024
- 关键词：Komagataella phaffii CRISPR/Cas9 Visual marker recycling Multi-fragment integration Large DNA fragment knockout Yeast assembled libraries
- The rational modification of the secretion pathway: The bidirectional grinding strategy on signal peptide and SecA in Bacillus subtilis被引量：9收藏
- 作者：Jiang, Zidong Zhang, Lujia Zhou, Wei Li, Hui Li, Yuanyi Qin, Weichuang Wang, Fengqing Wei, Dongzhi Gao, Bei
- 机构：East China Univ Sci & Technol;East China Normal Univ;East China Univ Sci & Technol
- 来源：BIOCHEMICAL ENGINEERING JOURNAL 2023
- 关键词：Bacillus subtilis Embedded-Model Signal peptide Secretory component SecA
- HP-DO3A-based amphiphilic MRI contrast agents and relaxation enhancement through their assembly with polyelectrolytes被引量：8收藏
- 作者：Zhu, Qin Yang, Heng Li, Yuanyuan Tian, Yu Wang, Wei Tang, Weijun Yuan, Yuan Hu, Aiguo
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Fudan Univ
- 来源：JOURNAL OF MATERIALS CHEMISTRY B 2016
- 关键词：Self assembly - Gadolinium compounds - Light scattering - Mass spectrometry - Polyelectrolytes - Synthesis (chemical) - Salts - Solutions - Hydrophobicity
- Cellulase mediated stress triggers the mutations of oleaginous yeast Trichosporon cutaneum with super-large spindle morphology and high lipid accumulation被引量：8收藏
- 作者：Liu, Qi Li, Yuanyuan Hou, Weiliang Zhang, Bin Bao, Jie
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：BIOTECHNOLOGY JOURNAL 2023
- 关键词：cell size cell wall structure cellulase microbial lipid oleaginous yeast
- Differential networking meta-analysis of gastric cancer across Asian and American racial groups被引量：8收藏
- 作者：Dai, Wentao Li, Quanxue Liu, Bing-Ya Li, Yi-Xue Li, Yuan-Yuan
- 机构：Shanghai Ctr Bioinformat Technol;East China Univ Sci & Technol;Shanghai Jiao Tong Univ;Shanghai Engn Res Ctr Pharmaceut Translat;Shanghai Ind Technol Inst
- 来源：BMC SYSTEMS BIOLOGY 2018
- 关键词：Gastric carcinoma (GC) Differential networking meta-analysis Cross-racial Conditional gene regulatory networks (GRN) Dysfunctional regulation mechanisms
- Identification of a CqCaspase gene with antiviral activity from red claw crayfish Cherax quadricarinatus被引量：7收藏
- 作者：li, Yan-yao Xie, Xiao-lu Ma, Xing-yuan Liu, Hai-peng
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Xiamen Univ
- 来源：DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY 2019
- 关键词：CqCaspase Antiviral activity Cherax quadricarinatus White spot syndrome virus
- Spherical Polyelectrolyte Brushes as a Novel Platform for Paramagnetic Relaxation Enhancement and Passive Tumor Targeting被引量：7收藏
- 作者：Zhu, Qin Yuan, Zhenyu Qian, Weiqiao Li, Yuanyuan Qiu, Zhiqiang Tang, Weijun Wang, Jie Ding, Yun Hu, Aiguo
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;Fudan Univ
- 来源：ADVANCED HEALTHCARE MATERIALS 2017
- 关键词：EPR effect magnetic resonance imaging relaxation enhancement spherical polyelectrolyte brushes
- Highly Sensitive In Vivo Imaging of Bacterial Infections with a Hydrophilicity-Switching, Self-Immobilizing, Near-Infrared Fluorogenic β-Lactamase Probe Enriched within Bacteria被引量：6收藏
- 作者：Chen, Fangfang Li, Yuyao Peng, Yan Zhu, Yifan He, Gao Zhang, Zhengwei Xie, Hexin
- 机构：East China Univ Sci & Technol;Fudan Univ;Fudan Univ
- 来源：ADVANCED SCIENCE 2025
- 关键词：beta-lactamases antibiotic resistance bacterial infections fluorescence probes in vivo imaging
- Regioselective Difluoromethane sulfonylation and Triflylation of Resorufin Derivatives被引量：4收藏
- 作者：Tan, Qingwei Zhao, Shuxuan Li, Yuyao Jiang, Jialing Tang, Huiling Chen, Yefeng Peng, Yan Xie, Hexin
- 机构：East China Univ Sci & Technol
- 来源：ORGANIC LETTERS 2021
- New Polyketide Congeners with Antibacterial Activities from an Endophytic Fungus Stemphylium globuliferum 17035 (China General Microbiological Culture Collection Center No. 40666)被引量：4收藏
- 作者：Li, Yingying Zhu, Guoliang Wang, Jing Yu, Junjie Ye, Ke Xing, Cuiping Ren, Biao Zhu, Bin Chen, Simin Lai, Lijun Li, Yue Hsiang, Tom Zhang, Lixin Liu, Xueting Zhang, Jingyu
- 机构：East China Univ Sci & Technol;Sichuan Univ;Sichuan Univ;East China Univ Sci & Technol;Univ Guelph
- 来源：JOURNAL OF FUNGI 2024
- 关键词：endophytic fungus polyketides
Stemphylium globuliferum antibacterial anticancer OSMAC strategy
- Partition dataset according to amino acid type improves the prediction of deleterious non-synonymous SNPs被引量：2收藏
- 作者：Yang, Jing Li, Yuan-Yuan Li, Yi-Xue Ye, Zhi-Qiang
- 机构：E China Univ Sci & Technol;Shanghai Ctr Bioinformat Technol;Peking Univ;Chinese Acad Sci
- 来源：BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 2012
- 关键词：Non-synonymous SNP Disease-association Dataset partition Machine learning
- A 4-OTBS benzyl-based protective group for carboxylic acids被引量：2收藏
- 作者：Fang, Zhijun Li, Yuyao Xie, Hexin
- 机构：East China Univ Sci & Technol
- 来源：TETRAHEDRON LETTERS 2019
- 关键词：Protective group Carboxylic acid 4-OTBS benzyl GGT probe
