成果/Result
- Recent developments in multimodality fluorescence imaging probes被引量：188收藏
- 作者：Zhao, Jianhong Chen, Junwei Ma, Shengnan Liu, Qianqian Huang, Lixian Chen, Xiani Lou, Kaiyan Wang, Wei
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Univ New Mexico
- 来源：ACTA PHARMACEUTICA SINICA B 2018
- 关键词：Optical imaging Fluorescence Multimodality Near-infrared fluorescence Nanoprobe Computedtomography Magneticresonance imaging Positronemissiontomo graphy Single-photonemission computedtomography Photoacoustic imaging
- Nickel-catalyzed methylation of aryl halides/tosylates with methyl tosylate被引量：79收藏
- 作者：Wang, Jiawang Zhao, Jianhong Gong, Hegui
- 机构：Shanghai Univ;Shanghai Univ;East China Univ Sci & Technol
- 来源：CHEMICAL COMMUNICATIONS 2017
- Enzymatic Cleavage and Subsequent Facile Intramolecular Transcyclization for in Situ Fluorescence Detection of γ-Glutamyltranspetidase Activities被引量：78收藏
- 作者：Tong, Hongjuan Zheng, Yongjun Zhou, Li Li, Xiangmin Qian, Rui Wang, Rui Zhao, Jianhong Lou, Kaiyan Wang, Wei
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Univ New Mexico
- 来源：ANALYTICAL CHEMISTRY 2016
- 关键词：Cancer cells - Cells - Diseases - Diagnosis - Cytology - Fluorescence spectroscopy - Probes - Enzymes - Product design
- Orchestration of dual cyclization processes and dual quenching mechanisms for enhanced selectivity and drastic fluorescence turn-on detection of cysteine被引量：46收藏
- 作者：Tong, Hongjuan Zhao, Jianhong Li, Xiangmin Zhang, Yajun Ma, Shengnan Lou, Kaiyan Wang, Wei
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Univ New Mexico
- 来源：CHEMICAL COMMUNICATIONS 2017
- LiHMDS-Promoted Palladium-Catalyzed Sonogashira Cross-Coupling of Aryl Fluorides with Terminal Alkynes被引量：42收藏
- 作者：He, Jingjing Yang, Kang Zhao, Jianhong Cao, Song
- 机构：ECUST
- 来源：ORGANIC LETTERS 2019
- Enantioselective Construction of CF3-Containing Spirooxindole γ-Lactones via Organocatalytic Asymmetric Michael/Lactonization被引量：41收藏
- 作者：Yang, Zhong-Tao Zhao, Jianhong Yang, Wu-Lin Deng, Wei-Ping
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：ORGANIC LETTERS 2019
- Asymmetric Synthesis of Spirooxindole β-lactams via Isothiourea-catalyzed Mannich/lactamization Reaction of Aryl Acetic Acids with Isatin-derived Ketimines被引量：26收藏
- 作者：Jin, Jing-Hai Zhao, Jianhong Yang, Wu-Lin Deng, Wei-Ping
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：ADVANCED SYNTHESIS & CATALYSIS 2019
- 关键词：[2+2] annulation asymmetric synthesis HBTM Mannich/lactamization reaction spirooxindole beta-lactams
- Synthesis of 2-arylbenzofuran-3-carbaldehydes via an organocatalytic [3+2] annulation/oxidative aromatization reaction被引量：16收藏
- 作者：Zhang, Huiwen Ma, Chunmei Zheng, Ziwei Sun, Rengwei Yu, Xinhong Zhao, Jianhong
- 机构：East China Univ Sci & Technol; East China Univ Sci & Technol
- 来源：CHEMICAL COMMUNICATIONS 2018
- Organocatalytic Enantioselective [8+4] Cycloadditions of Isobenzofulvenes for the Construction of Bicyclo[4.2.1]nonanes被引量：14收藏
- 作者：Zhao, Jianhong Zheng, Xing Gao, Yan-Shan Mao, Jia Wu, Shu-Xiao Yang, Wu-Lin Luo, Xiaoyan Deng, Wei-Ping
- 机构：East China Univ Sci & Technol; East China Univ Sci & Technol
- 来源：CHINESE JOURNAL OF CHEMISTRY 2021
- 关键词：Organocatalysis Isobenzofulvene Electron-deficient dienes Cycloaddition Enantioselectivity
- Secondary amine-catalyzed asymmetric formal aza [3+3] cycloaddition to construct enantioenriched piperidines derivatives被引量：10收藏
- 作者：Su, Ruo-Heng Ding, Xiang-Feng Wu, Shu-Xiao Zhao, Jian-Hong Deng, Wei-Ping
- 机构：East China Univ Sci & Technol
- 来源：TETRAHEDRON 2017
- 关键词：Organocatalysis Cycloaddition Piperidines derivatives
- Catalyst-Free ?-Alkylation-?-Hydroxylation of Oxindole with Alcohols被引量：9收藏
- 作者：Wu, Siwei Song, Wei Zhu, Runyu Hu, Jingwen Zhao, Lin Li, Zheyao Yu, Xinhong Xia, Chengcai Zhao, Jianhong
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;Taishan Med Univ
- 来源：JOURNAL OF ORGANIC CHEMISTRY 2022
- 关键词：Catalysts - Hydroxylation - Transition metals
- A ligand-free, powerful, and practical method for methoxylation of unactivated aryl bromides by use of the CuCl/HCOOMe/MeONa/MeOH system被引量：8收藏
- 作者：Guo, Ying Ji, Si-Zhe Chen, Cheng Liu, Hong-Wei Zhao, Jian-Hong Zheng, Yu-Lin Ji, Ya-Fei
- 机构：E China Univ Sci & Technol;Shanghai Ocean Univ;Shanghai New Asia Pharmaceut Co Ltd
- 来源：RESEARCH ON CHEMICAL INTERMEDIATES 2015
- 关键词：Cu-catalysis Unactivated aryl bromides Methoxylation Aryl methyl ethers Recovery of pure MeOH
- Improved Stereoselective Syntheses of (+)-Valiolamine and (+)-Valienamine Starting from (-)-Shikimic Acid被引量：8收藏
- 作者：Li, Fenglei Ding, Wei Quan, Na Wu, Jiajia He, Yungang Zhu, Xingliang Shi, Xiaoxin Zhao, Jianhong
- 机构：East China Univ Sci & Technol
- 来源：CHINESE JOURNAL OF CHEMISTRY 2017
- 关键词：valiolamine valienamine shikimic acid practical synthesis
- Highly Efficient and Practical Synthesis of the Key Intermediate of Telmisartan被引量：7收藏
- 作者：Zhao, Jianhong Xiong, Yicheng Yang, Wu-Lin Yang, Fan Jin, Yu
- 机构：East China Univ Sci & Technol
- 来源：ORGANIC PROCESS RESEARCH & DEVELOPMENT 2021
- 关键词：Telmisartan practical synthesis 1,7 '-dimethyl-2 '-propyl-2,5 '-bi(1H-benzimidazole) Duff reaction benzimidazole
- A practical ligand-free copper(I) bromide-catalyzed fluoroalkoxylation of unactivated aryl bromides被引量：5收藏
- 作者：Guo, Ying Li, Yu-Dao Chen, Cheng Zhao, Jian-Hong Liu, Hong-Wei Liao, Dao-Hua Ji, Ya-Fei
- 机构：E China Univ Sci & Technol
- 来源：RESEARCH ON CHEMICAL INTERMEDIATES 2016
- 关键词：Fluoroalkoxylation Ligand-free catalysis Unactivated aryl bromides Copper(I) bromide Aryl fluoroalkyl ethers
- Asymmetric α-spirocyclopropanation of oxindoles and benzofuranones via dynamic kinetic resolution被引量：5收藏
- 作者：Hu, Yang Yuan, Jie Li, Zheyao Zhao, Lin Zhao, Jianhong Yu, Xinhong
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：COMMUNICATIONS CHEMISTRY 2022
- Mild and Metal-Free Cross-Dehydrogenative Coupling of Nitrogen Heteroarenes with Aldehydes Enabled by Structural Hybridization of Promoting Reagents被引量：3收藏
- 作者：Zhao, Jianhong Qian, Kun Tong, Mengchao Yuan, Qiyang Zhang, Yongqiang
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Shanghai Pharmaceut Sch
- 来源：CHEMISTRYSELECT 2022
- 关键词：cross-dehydrogenative coupling nitrogen heteroarenes aldehydes structural hybridization promoting reagents
- Water-Mediated Three-Component Wittig-SNAr Reactions被引量：2收藏
- 作者：Xu, Zian Zhai, Wanwan Feng, Congpeng Liu, Hongwei Zhao, Jianhong Yu, Xinhong
- 机构：E China Univ Sci & Technol; E China Univ Sci & Technol
- 来源：SYNLETT 2015
- 关键词：three-component reaction Wittig reaction SNAr water
- High atomic utilization conversion of ethers into furancarbaldehydes via an ether oxidation iminium-ion activation cascade strategy被引量：1收藏
- 作者：Li, Zheyao Ma, Chunmei Zhao, Lin Lin, Zhongren Hu, Yang Zhao, Jianhong Yu, Xinhong
- 机构：East China Univ Sci & Technol; East China Univ Sci & Technol
- 来源：ORGANIC & BIOMOLECULAR CHEMISTRY 2023
- 关键词：Chemical activation - Ions - Oxidation - Synthesis (chemical)
- Unconventional Synthetic Process of Fasudil Hydrochloride: Costly Homopiperazine Was Avoided被引量：1收藏
- 作者：Zhao, Jianhong Wang, Dingding Yang, Wu-Lin Niu, Jinming Wu, Weiting
- 机构：East China Univ Sci & Technol
- 来源：ORGANIC PROCESS RESEARCH & DEVELOPMENT 2022
- 关键词：fasudil hydrochloride homopiperazine one-pot process practical synthesis
- 奎宁环促进的缺电性含氮芳杂环碳氢硅基化反应研究被引量：0收藏
- 作者：潘鹏 袁启洋 刘石惠 赵建宏 张永强
- 机构：华东理工大学药学院;嘉兴学院医学院
- 来源：《有机化学》 2022
- 关键词：奎宁环 缺电性含氮芳杂环 氢原子转移 硅自由基 碳氢硅基化反应
- 摘要：以过硫酸铵为氧化剂,以氢硅烷为硅基源,开发了一项奎宁环促进的缺电性含氮芳杂环碳氢硅基化反应新技术.新反应以氢原子转移和硅自由基生成为特征,绿色温和,操作简便,易于放大,底物适用范围广,官能团兼容性强,可有效实现多类型缺电...
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- Pd-Catalyzed Asymmetric Reactions Involving β-Hydride Elimination被引量：0收藏
- 作者：Chen, Ziqi Zheng, Qizhi Zhang, Ruinan Fang, Chao Zhang, Pei-Chao Chai, Xiaoyun Zhao, Qingjie Luo, Wenjun Zhao, Jianhong Xu, Bing Zhang, Zhan-Ming Zhang, Junliang
- 机构：Naval Med Univ;Fudan Univ;East China Univ Sci & Technol;Gannan Normal Univ;Fudan Zhangjiang Inst
- 来源：ACS CATALYSIS 2026
- 关键词：beta-H elimination palladium catalysis asymmetric catalysis enantioselectivity axial chirality inherent chirality central chirality
- Development of a Robust, Efficient, and Scalable Process for the Synthesis of Bisacodyl被引量：0收藏
- 作者：Bian, Wentao Chen, Jiamin Duan, Kongling Shen, Qilei Zhao, Jianhong
- 机构：East China Univ Sci & Technol
- 来源：ORGANIC PROCESS RESEARCH & DEVELOPMENT 2026
- 关键词：bisacodyl scalable synthesis high regioselectivity operational simplicity single protecting group
- High atomic utilization conversion of ethers into furancarbaldehydes via an ether oxidation iminium-ion activation cascade strategy被引量：0收藏
- 作者：Li, Zheyao Ma, Chunmei Zhao, Lin Lin, Zhongren Hu, Yang Zhao, Jianhong Yu, Xinhong
- 机构：East China Univ Sci & Technol; East China Univ Sci & Technol
- 来源：ORGANIC & BIOMOLECULAR CHEMISTRY 2023
- A Novel, Practical, and Efficient Synthetic Process for Chiral 10-Aza-isoergoline Scaffold of the Antipsychotic Candidate IHCH7041被引量：0收藏
- 作者：Li, Ruipeng Bian, Wentao Xie, Jianshu Xia, Guangxin Zhao, Jianhong
- 机构：East China Univ Sci & Technol;Shanghai Pharmaceut Holding Co Ltd
- 来源：ORGANIC PROCESS RESEARCH & DEVELOPMENT 2026
- 关键词：10-aza-isoergoline antipsychotic candidate process development chiral resolution
- A substituted tricyclohexylphosphane with "conformational lock"被引量：0收藏
- 作者：Liu, Ziyue Li, Tiejun Zhao, Jianhong Tang, Wenjun
- 机构：East China Univ Sci & Technol;Chinese Acad Sci;Univ Chinese Acad Sci
- 来源：TETRAHEDRON 2020
- 关键词：Tricyclohexylphosphane Conformational lock Ligand Cross-coupling Palladium
