成果/Result
- Hydrogen-bond-mediated asymmetric catalysis被引量：597收藏
- 作者：Yu, Xinhong Wang, Wei
- 机构：Univ New Mexico;E China Univ Sci & Technol
- 来源：CHEMISTRY-AN ASIAN JOURNAL 2008
- 关键词：asymmetric catalysis diols hydrogen bonds phosphoric acids ureas
- Organocatalysis: asymmetric cascade reactions catalysed by chiral secondary amines被引量：482收藏
- 作者：Yu, Xinhong Wang, Wei
- 机构：Univ New Mexico;E China Univ Sci & Technol
- 来源：ORGANIC & BIOMOLECULAR CHEMISTRY 2008
- 关键词：Rate constants - Amines
- Fluorescent Probes for the Detection of Hydrogen Sulfide in Biological Systems被引量：269收藏
- 作者：Xuan, Weimin Sheng, Chunquan Cao, Yanting He, Wenhan Wang, Wei
- 机构：Second Mil Med Univ;Univ New Mexico;E China Univ Sci & Technol
- 来源：ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 2012
- 关键词：azides fluorescein fluorescent probes hydrogen sulfide rhodamines
- Recent developments in multimodality fluorescence imaging probes被引量：188收藏
- 作者：Zhao, Jianhong Chen, Junwei Ma, Shengnan Liu, Qianqian Huang, Lixian Chen, Xiani Lou, Kaiyan Wang, Wei
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Univ New Mexico
- 来源：ACTA PHARMACEUTICA SINICA B 2018
- 关键词：Optical imaging Fluorescence Multimodality Near-infrared fluorescence Nanoprobe Computedtomography Magneticresonance imaging Positronemissiontomo graphy Single-photonemission computedtomography Photoacoustic imaging
- Dynamic Kinetic Resolution of Biaryl Lactones via a Chiral Bifunctional Amine Thiourea-Catalyzed Highly Atropoenantioselective Transesterification被引量：157收藏
- 作者：Yu, Chenguang Huang, He Li, Xiangmin Zhang, Yueteng Wang, Wei
- 机构：Univ New Mexico;E China Univ Sci & Technol;E China Univ Sci & Technol
- 来源：JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 2016
- 关键词：Enantioselectivity - Transesterification - Esters
- Organocatalytic enantioselective β-functionalization of aldehydes by oxidation of enamines and their application in cascade reactions被引量：140收藏
- 作者：Zhang, Shi-Lei Xie, He-Xin Zhu, Jin Li, Hao Zhang, Xin-Shuai Li, Jian Wang, Wei
- 机构：Chinese Acad Sci;Univ New Mexico;E China Univ Sci & Technol
- 来源：NATURE COMMUNICATIONS 2011
- Chitosan-graft-β-cyclodextrin nanoparticles as a carrier for controlled drug release被引量：135收藏
- 作者：Yuan, Zeting Ye, Yajing Gao, Feng Yuan, Huihui Lan, Minbo Lou, Kaiyan Wang, Wei
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol;E China Univ Sci & Technol;Univ New Mexico
- 来源：INTERNATIONAL JOURNAL OF PHARMACEUTICS 2013
- 关键词：Chitosan Cyclodextrin Ionic gelation Nano-drug delivery system
- State-of-the-art strategies for targeting protein-protein interactions by small-molecule inhibitors被引量：132收藏
- 作者：Sheng, Chunquan Dong, Guoqiang Miao, Zhenyuan Zhang, Wannian Wang, Wei
- 机构：Second Mil Med Univ;Univ New Mexico;E China Univ Sci & Technol;E China Univ Sci & Technol
- 来源：CHEMICAL SOCIETY REVIEWS 2015
- Potent Dual BET/HDAC Inhibitors for Efficient Treatment of Pancreatic Cancer被引量：129收藏
- 作者：He, Shipeng Dong, Guoqiang Li, Yu Wu, Shanchao Wang, Wei Sheng, Chunquan
- 机构：Second Mil Med Univ;East China Univ Sci & Technol;Shanghai Univ;Univ Arizona;Univ Arizona
- 来源：ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 2020
- 关键词：anticancer antitumor agents drug discovery heterocyles inhibitors
- Visible-Light-Promoted Nickel- and Organic-Dye-Cocatalyzed Formylation Reaction of Aryl Halides and Triflates and Vinyl Bromides with Diethoxyacetic Acid as a Formyl Equivalent被引量：126收藏
- 作者：Huang, He Li, Xiangmin Yu, Chenguang Zhang, Yueteng Mariano, Patrick S. Wang, Wei
- 机构：Univ New Mexico;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 2017
- 关键词：flow chemistry formylation nickel catalysis photoredox catalysis synthetic methods
- Near-infrared fluorescent probes for imaging of amyloid plaques in Alzheimer's disease被引量：123收藏
- 作者：Tong, Hongjuan Lou, Kaiyan Wang, Wei
- 机构：E China Univ Sci & Technol;Univ New Mexico
- 来源：ACTA PHARMACEUTICA SINICA B 2015
- 关键词：Alzheiimer's disease Blood-brain barrier Fluoresence probe Near-infrared fluorescence Optical imaging Amyloid-beta plagues
- Bifunctional Cinchona Alkaloid Thiourea Catalyzed Highly Efficient, Enantioselective Aza-Henry Reaction of Cyclic Trifluoromethyl Ketimines: Synthesis of Anti-HIV Drug DPC 083被引量：122收藏
- 作者：Xie, Hexin Zhang, Yinan Zhang, Shilei Chen, Xiaobei Wang, Wei
- 机构：Univ New Mexico;E China Univ Sci & Technol
- 来源：ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 2011
- 关键词：alkaloids asymmetric synthesis aza-Henry reaction drug synthesis organocatalysis
- Chemo- and Regioselective Organo-Photoredox Catalyzed Hydroformylation of Styrenes via a Radical Pathway被引量：119收藏
- 作者：Huang, He Yu, Chenguang Zhang, Yueteng Zhang, Yongqiang Mariano, Patrick S. Wang, Wei
- 机构：Univ New Mexico;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 2017
- 关键词：Carboxylation - Catalysis - Regioselectivity - Hydroformylation - Free radicals - Styrene
- A FRET-based ratiometric fluorescent and colorimetric probe for the facile detection of organophosphonate nerve agent mimic DCP被引量：111收藏
- 作者：Xuan, Weimin Cao, Yanting Zhou, Jiahong Wang, Wei
- 机构：Univ New Mexico;Nanjing Normal Univ;E China Univ Sci & Technol
- 来源：CHEMICAL COMMUNICATIONS 2013
- Divergent Cascade Construction of Skeletally Diverse "Privileged" Pyrazole-Derived Molecular Architectures被引量：103收藏
- 作者：Zhang, Yongqiang Wu, Shanchao Wang, Shengzheng Fang, Kun Dong, Guoqiang Liu, Na Miao, Zhenyuan Yao, Jianzhong Li, Jian Zhang, Wannian Sheng, Chunquan Wang, Wei
- 机构：Second Mil Med Univ;E China Univ Sci & Technol;Univ New Mexico
- 来源：EUROPEAN JOURNAL OF ORGANIC CHEMISTRY 2015
- 关键词：Organocatalysis Divergent synthesis Molecular diversity Nitrogen heterocycles Spiro compounds Drug design
- Catalytic Enantioselective Henry Reactions of Isatins: Application in the Concise Synthesis of (S)-(-)-Spirobrassinin被引量：100收藏
- 作者：Liu, Lu Zhang, Shilei Xue, Fei Lou, Guangshun Zhang, Haoyi Ma, Shichao Duan, Wenhu Wang, Wei
- 机构：Univ New Mexico;E China Univ Sci & Technol;Chinese Acad Sci
- 来源：CHEMISTRY-A EUROPEAN JOURNAL 2011
- 关键词：Henry reaction isatins natural products organocatalysis oxindoles
- Catalytic enantioselective henry reactions of isatins: Application in the concise synthesis of (S)-(-)-spirobrassinin被引量：98收藏
- 作者：Liu, Lu Zhang, Shilei Xue, Fei Lou, Guangshun Zhang, Haoyi Ma, Shichao Duan, Wenhu Wang, Wei
- 机构： School of Pharmacy; Shanghai Institute of Materia Medica; Department of Chemistry and Chemical Biology
- 来源：Chemistry - A European Journal 2011
- 关键词：Chromatography - Catalysis
- Facile Creation of 3-Indolyl-3-hydroxy-2-oxindoles by an Organocatalytic Enantioselective Friedel-Crafts Reaction of Indoles with Isatins被引量：97收藏
- 作者：Deng, Jing Zhang, Shilei Ding, Peng Jiang, Hualiang Wang, Wei Li, Jian
- 机构：E China Univ Sci & Technol;Univ New Mexico;Chinese Acad Sci
- 来源：ADVANCED SYNTHESIS & CATALYSIS 2010
- 关键词：asymmetric Friedel-Crafts reaction indoles isatins organocatalysis
- Simple Cyclohexanediamine-Derived Primary Amine Thiourea Catalyzed Highly Enantioselective Conjugate Addition of Nitroalkanes to Enones被引量：94收藏
- 作者：Mei, Kui Jin, Mei Zhang, Shilei Li, Ping Liu, Wenjing Chen, Xiaobei Xue, Fei Duan, Wenhu Wang, Wei
- 机构：E China Univ Sci & Technol;Chinese Acad Sci;Univ New Mexico
- 来源：ORGANIC LETTERS 2009
- Practical synthesis of C1 deuterated aldehydes enabled by NHC catalysis被引量：94收藏
- 作者：Geng, Huihui Chen, Xiaobei Gui, Jingjing Zhang, Yueteng Shen, Zuyuan Qian, Pengfei Chen, Junwei Zhang, Shilei Wang, Wei
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Soochow Univ;Soochow Univ;Univ Arizona
- 来源：NATURE CATALYSIS 2019
- 关键词：Reaction intermediates - Cost effectiveness - Condensation reactions - Deuterium - Catalysis
- Synthesis of Chiral 3-Substituted Phthalides by a Sequential Organocatalytic Enantioselective Aldol-Lactonization Reaction. Three-Step Synthesis of (S)-(-)-3-Butylphthalide被引量：90收藏
- 作者：Zhang, Haoyi Zhang, Shilei Liu, Lu Luo, Guangshun Duan, Wenhu Wang, Wei
- 机构：E China Univ Sci & Technol;Chinese Acad Sci;Univ New Mexico
- 来源：JOURNAL OF ORGANIC CHEMISTRY 2010
- Direct, facile aldehyde and ketone α-selenenylation reactions promoted by L-prolinamide and pyrrolidine sulfonamide organocatalysts被引量：89收藏
- 作者：Wang, Jian Li, Hao Mei, Yujiang Lou, Bihshow Xu, Dingguo Xie, Daiqian Guo, Hua Wang, Wei
- 机构：Univ New Mexico;Nanjing Univ;E China Univ Sci & Technol
- 来源：JOURNAL OF ORGANIC CHEMISTRY 2005
- 关键词：Aldehydes - Amines - Hydrogen bonds - Ketones
- Direct Cα-heteroarylation of structurally diverse ethers via a mild N-hydroxysuccinimide mediated cross-dehydrogenative coupling reaction被引量：89收藏
- 作者：Liu, Shihui Liu, Aoxia Zhang, Yongqiang Wang, Wei
- 机构：East China Univ Sci & Technol;Univ New Mexico
- 来源：CHEMICAL SCIENCE 2017
- 关键词：Free radical reactions - Atoms
- Organocatalytic Enantioselective Direct Additions of Aldehydes to 4-Vinylpyridines and Electron-Deficient Vinylarenes and Their Synthetic Applications被引量：87收藏
- 作者：Wang, Sinan Li, Xiangmin Liu, Hongwei Xu, Li Zhuang, Jinchen Li, Jian Li, Hao Wang, Wei
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol;Univ New Mexico
- 来源：JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 2015
- 关键词：Ethers - Synthesis (chemical) - Catalysis - Enantioselectivity - Chemical activation - Pyridine
- A Direct Amine-Palladium Acetate Cocatalyzed Saegusa Oxidation Reaction of Unmodified Aldehydes to α,β-Unsaturated Aldehydes被引量：85收藏
- 作者：Zhu, Jin Liu, Jie Ma, Ruoqun Xie, Hexin Li, Jian Jiang, Hualiang Wang, Wei
- 机构：E China Univ Sci & Technol;Univ New Mexico;Chinese Acad Sci
- 来源：ADVANCED SYNTHESIS & CATALYSIS 2009
- 关键词：aminocatalysis organocatalysis Saegusa reaction alpha,beta-unsaturated aldehydes
- Organocatalytic Aerobic Oxidation of Benzylic sp3 C-H Bonds of Ethers and Alkylarenes Promoted by a Recyclable TEMPO Catalyst被引量：84收藏
- 作者：Zhang, Zhiguang Gao, Yuan Liu, Yuan Li, Jianjun Xie, Hexin Li, Hao Wang, Wei
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol;Univ New Mexico
- 来源：ORGANIC LETTERS 2015
- Organocatalytic Enantioselective Cross-Aldol Reactions of Aldehydes with Isatins: Formation of Two Contiguous Quaternary Centered 3-Substituted 3-Hydroxyindol-2-ones被引量：81收藏
- 作者：Xue, Fei Zhang, Shilei Liu, Lu Duan, Wenhu Wang, Wei
- 机构：E China Univ Sci & Technol;Univ New Mexico
- 来源：CHEMISTRY-AN ASIAN JOURNAL 2009
- 关键词：aldehydes aldol isatins organocatalysis
- An Organocatalytic Cascade Approach toward Polysubstituted Quinolines and Chiral 1,4-Dihydroquinolines-Unanticipated Effect of N-Protecting Groups被引量：80收藏
- 作者：Zhang, Xinshuai Song, Xixi Li, Hao Zhang, Shilei Chen, Xiaobei Yu, Xinhong Wang, Wei
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol;Univ New Mexico
- 来源：ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 2012
- 关键词：1 4-dihydroquinolines cascade reactions divergent synthesis organocatalysis quinolines
- Enzymatic Cleavage and Subsequent Facile Intramolecular Transcyclization for in Situ Fluorescence Detection of γ-Glutamyltranspetidase Activities被引量：78收藏
- 作者：Tong, Hongjuan Zheng, Yongjun Zhou, Li Li, Xiangmin Qian, Rui Wang, Rui Zhao, Jianhong Lou, Kaiyan Wang, Wei
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Univ New Mexico
- 来源：ANALYTICAL CHEMISTRY 2016
- 关键词：Cancer cells - Cells - Diseases - Diagnosis - Cytology - Fluorescence spectroscopy - Probes - Enzymes - Product design
- New small-molecule drug design strategies for fighting resistant influenza A被引量：78收藏
- 作者：Shen, Zuyuan Lou, Kaiyan Wang, Wei
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol;Univ New Mexico
- 来源：ACTA PHARMACEUTICA SINICA B 2015
- 关键词：Influenza A virus Drug discovery Resistance M2 ion channel Neuramindase
