成果/Result
- Involvement of LuxS in the regulation of motility and flagella biogenesis in Vibrio alginolyticus被引量：51收藏
- 作者：Tian, Yang Wang, Qiyao Liu, Qin Ma, Yue Cao, Xiaodan Guan, Lingyu Zhang, Yuanxing
- 机构： State Key Laboratory of Bioreactor Engineering
- 来源：Bioscience, Biotechnology and Biochemistry 2008
- 关键词：Bacteria - Bioassay - Gene expression - Real time control
- Roles of Hfq in the stress adaptation and virulence in fish pathogen Vibrio alginolyticus and its potential application as a target for live attenuated vaccine被引量：49收藏
- 作者：Liu, Huan Wang, Qiyao Liu, Qin Cao, Xiaodan Shi, Cunbin Zhang, Yuanxing
- 机构：E China Univ Sci & Technol;Chinese Acad Fishery Sci
- 来源：APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 2011
- 关键词：Hfq Quorum sensing Stress resistance Extracellular protease Vibrio alginolyticus
- An invasive and low virulent Edwardsiella tarda esrB mutant promising as live attenuated vaccine in aquaculture被引量：49收藏
- 作者：Yang, Weizheng Wang, Lixia Zhang, Lingzhi Qu, Jiangbo Wang, Qiyao Zhang, Yuanxing
- 机构：E China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol;TianYuan Aquat Prod Co Ltd
- 来源：APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 2015
- 关键词：Edwardsiella tarda T3SS T6SS esrB Invasive phenotype Vaccine
- Characterization of Edwardsiella tarda rpoS: Effect on serum resistance, chondroitinase activity, biofilm formation, and autoinducer synthetases expression被引量：40收藏
- 作者：Xiao, Jingfan Wang, Qiyao Liu, Qin Xu, Lili Wang, Xin Wu, Haizhen Zhang, Yuanxing
- 机构： State Key Laboratory of Bioreactor Engineering
- 来源：Applied Microbiology and Biotechnology 2009
- 关键词：Biofilms - Body fluids - Gene expression
- Interplay between ferric uptake regulator Fur and horizontally acquired virulence regulator EsrB coordinates virulence gene expression in Edwardsiella piscicida被引量：38收藏
- 作者：Shao, Shuai Li, Chunli Zhao, Luyao Zhang, Yuanxing Yin, Kaiyu Wang, Qiyao
- 机构：East China Univ Sci & Technol;Shanghai Business Sch;Qingdao Natl Lab Marine Sci & Technol;Southern Marine Sci & Engn Guangdong Lab Zhuhai;Shanghai Engn Res Ctr Maricultured Anim Vaccines
- 来源：MICROBIOLOGICAL RESEARCH 2021
- 关键词：Edwardsiella piscicida iron uptake system Fur EsrB biofilm formation virulence
- Isolation of a Virulent Aeromonas salmonicida subsp. masoucida Bacteriophage and Its Application in Phage Therapy in Turbot (Scophthalmus maximus)被引量：36收藏
- 作者：Xu, Zhenhe Jin, Peng Zhou, Xiangshan Zhang, Yuanxing Wang, Qiyao Liu, Xiaohong Shao, Shuai Liu, Qin
- 机构：East China Univ Sci & Technol;Southern Marine Sci & Engn Guangdong Lab Zhuhai;Shanghai Engn Res Ctr Maricultured Anim Vaccines
- 来源：APPLIED AND ENVIRONMENTAL MICROBIOLOGY 2021
- 关键词：Aeromonas salmonicida subsp. masoucida antibacterial aquaculture phage therapy turbot Scophthalmus maximus
- A programmable high-expression yeast platform responsive to user-defined signals被引量：35收藏
- 作者：Liu, Qi Song, Lili Peng, Qiangqiang Zhu, Qiaoyun Shi, Xiaona Xu, Mingqiang Wang, Qiyao Zhang, Yuanxing Cai, Menghao
- 机构：East China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg
- 来源：SCIENCE ADVANCES 2022
- 关键词：Recombinant protEIns - Transcription
- A novel multivalent vaccine based on secretary antigen-delivery induces protective immunity against Vibrio anguillarum and Aeromonas hydrophila被引量：31收藏
- 作者：Zhou, Lingyun Wang, Xiuhua Liu, Qin Wang, Qiyao Zhao, Yan Zhang, Yuanxing
- 机构： State Key Laboratory of Bioreactor Engineering; Yellow Sea Fisheries Research Institute
- 来源：Journal of Biotechnology 2010
- 关键词：Physiology - Strain - Antigens
- Secretory delivery of heterologous protEIns in attenuated Vibrio anguillarum for potential use in vaccine design被引量：28收藏
- 作者：Zhou, Lingyun Liu, Qin Wang, Qiyao Ma, Yue Xu, Yuzhou Yang, Zhao Zhao, Yan Zhang, Yuanxing
- 机构： State Key Laboratory of Bioreactor Engineering
- 来源：Applied Microbiology and Biotechnology 2008
- 关键词：Escherichia coli - Antigens - Peptides - Blood - Fluorescence
- Novel bacterial surface display systems based on outer membrane anchoring elements from the marine bacterium Vibrio anguillarum被引量：26收藏
- 作者：Yang, Zhao Liu, Qin Wang, Qiyao Zhang, Yuanxing
- 机构： State Key Laboratory of Bioreactor Engineering; State Key Laboratory of Bioreactor Engineering
- 来源：Applied and Environmental Microbiology 2008
- 关键词：Cell membranes - Activation analysis - Escherichia coli - Macromolecules - Vaccines - Display devices - Amino acids
- VqsA, a Novel LysR-Type Transcriptional Regulator, Coordinates Quorum Sensing (QS) and Is Controlled by QS To Regulate Virulence in the Pathogen Vibrio alginolyticus被引量：25收藏
- 作者：Gao, Xiating Wang, Xuetong Mao, Qiaoqiao Xu, Rongjing Zhou, Xiaohui Ma, Yue Liu, Qin Zhang, Yuanxing Wang, Qiyao
- 机构：East China Univ Sci & Technol;Shanghai Engn Res Ctr Maricultured Anim Vaccines;Univ Connecticut;Yangzhou Univ;Yantai Tianyuan Aquat Co Ltd
- 来源：APPLIED AND ENVIRONMENTAL MICROBIOLOGY 2018
- 关键词：Vibrio alginolyticus quorum sensing LuxR AphA VqsA virulence bacterial one-hybrid assay MQSR
- An engineered quorum-sensing-based whole-cell biosensor for active degradation of organophosphates被引量：25收藏
- 作者：He, Jianwei Zhang, Xiaoyan Qian, Yuanyi Wang, Qiyao Bai, Yunpeng
- 机构：East China Univ Sci & Technol
- 来源：BIOSENSORS & BIOELECTRONICS 2022
- 关键词：Whole-cell biosensor Synthetic biology Genetic circuits Quorum sensing Degradation
- Stationary phase-dependent accumulation of ectoine is an efficient adaptation strategy in Vibrio anguillarum against cold stress被引量：24收藏
- 作者：Ma, Yue Wang, Qiyao Xu, Wensheng Liu, Xiaohong Gao, Xiating Zhang, Yuanxing
- 机构：East China Univ Sci & Technol;Shanghai Engn Res Ctr Maricultured Anim Vaccines;Shanghai Collaborat Innovat Ctr Biomfg;Beijing Univ Agr
- 来源：MICROBIOLOGICAL RESEARCH 2017
- 关键词：Vibrio anguillarum Compatible solutes Ectoine ectABC proVWX Cold adaptation
- Roles of virulence regulator ToxR in viable but non-culturable formation by controlling reactive oxygen species resistance in pathogen Vibrio alginolyticus被引量：24收藏
- 作者：Zhou, Mengqing Huang, Yuping Zhang, Yuanxing Wang, Qiyao Ma, Yue Shao, Shuai
- 机构：East China Univ Sci & Technol;Southern Marine Sci & Engn Guangdong Lab Zhuhai;Shanghai Engn Res Ctr Maricultured Anim Vaccines
- 来源：MICROBIOLOGICAL RESEARCH 2022
- 关键词：VBNC Vibrio alginolyticus ToxR Virulence ROS
- Alternative Sigma Factor RpoX Is a Part of the RpoE Regulon and Plays Distinct Roles in Stress Responses, Motility, Biofilm Formation, and Hemolytic Activities in the Marine Pathogen Vibrio alginolyticus被引量：23收藏
- 作者：Gu, Dan Zhang, Jun Hao, Yuan Xu, Rongjing Zhang, Yuanxing Ma, Yue Wang, Qiyao
- 机构：East China Univ Sci & Technol;Shanghai Engn Res Ctr Maricultured Anim Vaccines;Yangzhou Univ;Yantai Tianyuan Aquat Co & Td
- 来源：APPLIED AND ENVIRONMENTAL MICROBIOLOGY 2019
- 关键词：ChIP-seq RNA-seq RpoE RpoX Vibrio alginolyticus virulence
- An immunochromatographic test strip for rapid detection of fish pathogen Edwardsiella tarda被引量：23收藏
- 作者：Liu, Hesong Wang, Yue Xiao, Jingfan Wang, Qiyao Liu, Qin Zhang, Yuanxing
- 机构： State Key Laboratory of Bioreactor Engineering; Shanghai Collaborative Innovation Center for Biomanufacturing Technology
- 来源：Bioresources and Bioprocessing 2015
- 关键词：Aquaculture - Chemical detection - Gold nanoparticles - Losses - Mammals - Monoclonal antibodies - Pathogens - Tissue
- An effective established biosensor of bifunctional probes-labeled AuNPs combined with LAMP for detection of fish pathogen Streptococcus iniae被引量：23收藏
- 作者：Zhou, Ya Xiao, Jingfan Ma, Xin Wang, Qiyao Zhang, Yuanxing
- 机构：East China Univ Sci & Technol;Shanghai Engn Res Ctr Maricultured Anim Vaccines;Shanghai Collaborat Innovat Ctr Biomfg
- 来源：APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 2018
- 关键词：LAMP Gold nanoparticles Bifunctional probes Streptococcus iniae
- Surface Display of Aeromonas hydrophila GAPDH in Attenuated Vibrio anguillarum to Develop a Noval Multivalent Vector Vaccine被引量：20收藏
- 作者：Zhao, Yan Liu, Qin Wang, Xiuhua Zhou, Lingyun Wang, Qiyao Zhang, Yuanxing
- 机构：E China Univ Sci & Technol;Chinese Acad Fishery Sci
- 来源：MARINE BIOTECHNOLOGY 2011
- 关键词：Aeromonas hydrophila Vibrio anguillarum Surface display Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) Multivalent vaccine
- MviN mediates the regulation of environmental osmotic pressure on esrB to control the virulence in the marine fish pathogen Edwardsiella piscicida被引量：19收藏
- 作者：Yin, Kaiyu Zhang, Jin Ma, Jiabao Jin, Peng Ma, Yue Zhang, Yuanxing Liu, Xiaohong Wang, Qiyao
- 机构：East China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol;Shanghai Engn Res Ctr Maricultured Anim Vaccines
- 来源：MICROBIOLOGICAL RESEARCH 2020
- 关键词：Edwardsiella piscicida EsrB Lipid II flippase Osmotic pressure In vivo colonization
- PepA binds to and negatively regulates esrB to control virulence in the fish pathogen Edwardsiella piscicida被引量：17收藏
- 作者：Yin, Kaiyu Peng, Yue Ahmed, Moamer A. H. Ma, Jiabao Xu, Rongjing Zhang, Yuanxing Ma, Yue Wang, Qiyao
- 机构：East China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol;Shanghai Engn Res Ctr Maricultured Anim Vaccines;Yantai Tianyuan Aquat Co Ltd
- 来源：MICROBIOLOGICAL RESEARCH 2020
- 关键词：Edwardsiella piscicida Pull-down EsrB Leucyl aminopeptidase In vivo colonization
- Therapeutic efficacies of two newly isolated Edwardsiella phages against Edwardsiella piscicida infection被引量：16收藏
- 作者：Xu, Zhenhe Shao, Shuai Ding, Zihan Zhang, Yuanxing Wang, Qiyao Liu, Xiaohong Liu, Qin
- 机构：East China Univ Sci & Technol;Southern Marine Sci & Engn Guangdong Lab Zhuhai;Shanghai Engn Res Ctr Maricultured Anim Vaccines
- 来源：MICROBIOLOGICAL RESEARCH 2022
- 关键词：Aquaculture Cocktail Edwardsiella piscicida Phage therapy Turbot Zebrafish
- Complete genome sequence of the marine fish pathogen Vibrio anguillarum and genome-wide transposon mutagenesis analysis of genes essential for in vivo infection被引量：15收藏
- 作者：Yang Guanhua Wang, Cheng Wang, Xuetong Ma, Ruiqing Zheng, Huajun Liu, Qin Zhang, Yuanxing Ma, Yue Wang, Qiyao
- 机构：East China Univ Sci & Technol;Qingdao Natl Lab Marine Sci & Technol;Shanghai Engn Res Ctr Maricultured Anim Vaccines;Chinese Natl Human Genome Ctr Shanghai
- 来源：MICROBIOLOGICAL RESEARCH 2018
- 关键词：Genome sequence Tn-seq Vibrio anguillarum In vivo fitness Conditionally essential genes
- Genome-Wide Identification of Fitness Factors in Seawater for Edwardsiella piscicida被引量：13收藏
- 作者：Wei, Lifan Wu, Yanyan Yang, Guanhua Xu, Rongjing Liu, Xiaohong Liu, Qin Zhang, Yuanxing Ma, Yue Wang, Qiyao
- 机构：East China Univ Sci & Technol;Shanghai Engn Res Ctr Maricultured Anim Vaccines;Shanghai Collaborat Innovat Ctr Biomfg;Yantai Tianyuan Aquat Co Ltd
- 来源：APPLIED AND ENVIRONMENTAL MICROBIOLOGY 2019
- 关键词：Edwardsiella piscicida T3SS transposon insertion sequencing TIS oxidative phosphorylation seawater temperature
- A ΣE-mediated temperature gauge orchestrates type VI secretion system, biofilm formation and cell invasion in pathogen Pseudomonas plecoglossicida被引量：12收藏
- 作者：Zhang, Yibei Huang, Yuping Ding, Haoyuan Ma, Jiabao Tong, Xinyu Zhang, Yuanxing Tao, Zhen Wang, Qiyao
- 机构：East China Univ Sci & Technol;Southern Marine Sci & Engn Guangdong Lab Zhuhai;Zhejiang Ocean Univ;Shanghai Engn Res Ctr Maricultured Anim Vaccines
- 来源：MICROBIOLOGICAL RESEARCH 2023
- 关键词：Temperature Sigma factor T6SS Pseudomonas plecoglossicida
- AI 赋能虚实递进的生物医药新工科实习教学体系的构建被引量：12收藏
- 作者：Wan, Junfen Cai, Menghao Wang, Qiyao
- 机构： Department of Bioengineering
- 来源：[1] Department of Bioengineering, School of Bioengineering, East China University of Science and Technology, Shanghai, 200237, China 2026
- Differential binding of LuxR in response to temperature gauges switches virulence gene expression in Vibrio alginolyticus被引量：12收藏
- 作者：Cai, Jingxiao Hao, Yuan Xu, Rongjing Zhang, Yuanxing Ma, Yue Zhang, Yibei Wang, Qiyao
- 机构：East China Univ Sci & Technol;Southern Marine Sci & Engn Guangdong Lab Zhuhai;Shanghai Engn Res Ctr Maricultured Anim Vaccines;Shanghai Collaborat Innovat Ctr Biomfg;Yantai Tianyuan Aquat Co Ltd
- 来源：MICROBIOLOGICAL RESEARCH 2022
- 关键词：Bacterial pathogen ChIP-seq LuxR Vibrio alginolyticus Virulence
- Transposon insertion sequencing analysis unvEIls novel genes involved in luxR expression and quorum sensing regulation in Vibrio alginolyticus被引量：9收藏
- 作者：Zhang, Yibei Wu, Xiao Cai, Jingxiao Chen, Mo Zhang, Jun Shao, Shuai Zhang, Yuanxing Ma, Yue Wang, Qiyao
- 机构：East China Univ Sci & Technol;Southern Marine Sci & Engn Guangdong Lab Zhuhai;Shanghai Engn Res Ctr Maricultured Anim Vaccines
- 来源：MICROBIOLOGICAL RESEARCH 2023
- 关键词：Vibrio alginolyticus LuxR Temperature Transposon insertion sequencing (Tn-seq)
- Edwardsiella induces microtubule-severing in host epithelial cells被引量：8收藏
- 作者：Aggarwal, Priyanka Wei, Lifan Cao, Yuping Liu, Qin Guttman, Julian A. Wang, Qiyao Leung, Ka Yin
- 机构：Simon Fraser Univ;East China Univ Sci & Technol;Guangdong Technion;Shanghai Engn Res Ctr Marine Cultured Anim Vaccin;Shanghai Collaborat Innovat Ctr Biomfg
- 来源：MICROBIOLOGICAL RESEARCH 2019
- 关键词：E. piscicida Fish pathogen Microtubule disassembly Interaction with epithelial cells
- Coordinate regulation of carbohydrate metabolism and virulence by PtsH in pathogen Edwardsiella piscicida被引量：8收藏
- 作者：Mao, Qiaoqiao Jiang, Jihao Wu, Xiao Xu, Rongjing Ma, Yue Zhang, Yuanxing Shao, Shuai Wang, Qiyao
- 机构：East China Univ Sci & Technol;Yantai Tianyuan Aquat Co Ltd;Shanghai Engn Res Ctr Maricultured Anim Vaccines;Southern Marine Sci & Engn Guangdong Lab Zhuhai
- 来源：APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 2022
- 关键词：Edwardsiella piscicida Mannose Phosphotransferase system Type III secretion system (T3SS) Virulence
- Phosphorylation of PppA at threonine 253 controls T6SS2 expression and bacterial killing capacity in the marine pathogen Vibrio alginolyticus被引量：6收藏
- 作者：Yang, Zhen Wang, Xuetong Xu, Wensheng Zhou, Mian Zhang, Yuanxing Ma, Yue Wang, Qiyao
- 机构：East China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg;Shanghai Engn Res Ctr Maricultured Anim Vaccines;Beijing Univ Agr
- 来源：MICROBIOLOGICAL RESEARCH 2018
- 关键词：T6SS2 Vibrio alginolyticus PppA QS Bacterial killing
