成果/Result
- Multifunctional magnetic-plasmonic nanoparticles for fast concentration and sensitive detection of bacteria using SERS被引量：111收藏
- 作者：Zhang, Lei Xu, Jiajie Mi, Luo Gong, Heng Jiang, Shaoyi Yu, Qiuming
- 机构：Univ Washington;E China Univ Sci & Technol
- 来源：BIOSENSORS & BIOELECTRONICS 2012
- 关键词：Multifunctional nanoparticles Magnetic concentration SERS Bacteria detection
- Surface-enhanced Raman scattering on gold quasi-3D nanostructure and 2D nanohole arrays被引量：79收藏
- 作者：Yu, Qiuming Braswell, Scott Christin, Brian Xu, Jiajie Wallace, Paul M. Gong, Heng Kaminsky, Dmitry
- 机构：Univ Washington;E China Univ Sci & Technol
- 来源：NANOTECHNOLOGY 2010
- 关键词：Molecules - Plasmonics - Substrates - Gold - Surface scattering - Raman scattering - Finite difference time domain method - Microchannels - Electric fields - Nanostructures
- Tailoring Plasmonic Nanostructures for Optimal SERS Sensing of Small Molecules and Large Microorganisms被引量：47收藏
- 作者：Xu, Jiajie Zhang, Lei Gong, Heng Homola, Jiri Yu, Qiuming
- 机构：Univ Washington;E China Univ Sci & Technol;Acad Sci Czech Republic
- 来源：SMALL 2011
- 关键词：Plasmonics - Finite difference time domain method - Gold - Metallic films - Nanostructures - Electric fields - Raman scattering - Surface scattering - Molecules
- Understanding the effects of dielectric medium, substrate, and depth on electric fields and SERS of quasi-3D plasmonic nanostructures被引量：44收藏
- 作者：Xu, Jiajie Kvasnicka, Pavel Idso, Matthew Jordan, Roger W. Gong, Heng Homola, Jiri Yu, Qiuming
- 机构：Univ Washington;Acad Sci Czech Republic;E China Univ Sci & Technol;Texas A&M Univ
- 来源：OPTICS EXPRESS 2011
- 关键词：Nanostructures - Surface plasmons - Finite difference time domain method - Gold - ITO glass - Electric fields - Plasmonics - Fabry-Perot interferometers
- Light transmission and surface-enhanced raman scattering of quasi-3D plasmonic nanostructure arrays with deep and shallow Fabry-Pérot nanocavities被引量：40收藏
- 作者：Xu, Jiajie Guan, Phillip Kvasnic?ka, Pavel Gong, Heng Homola, Jir?í Yu, Qiuming
- 机构： Department of Chemical Engineering; State Key Laboratory of Bioreactor Engineering; Institute of Photonics and Electronics
- 来源：Journal of Physical Chemistry C 2011
- 关键词：Surface scattering - Finite difference time domain method - Photoresists - Electric fields - Fabry-Perot interferometers - Surface plasmons - Plasmonics - Gold - Raman scattering - Nanostructures
- In Situ Strain-Level Detection and Identification of Vibrio parahaemolyticus Using Surface-Enhanced Raman Spectroscopy被引量：37收藏
- 作者：Xu, Jiajie Turner, Jeffrey W. Idso, Matthew Biryukov, Stanley V. Rognstad, Laurel Gong, Heng Trainer, Vera L. Wells, Mark L. Strom, Mark S. Yu, Qiuming
- 机构：Univ Washington;NOAA;Univ Maine;E China Univ Sci & Technol;Tennessee Technol Univ
- 来源：ANALYTICAL CHEMISTRY 2013
- 关键词：Finite difference time domain method - Light transmission - Substrates - Plasmonics - Bacteria - Raman spectroscopy
- Optical properties and surface-enhanced Raman scattering of quasi-3D gold plasmonic nanostructures被引量：35收藏
- 作者：Xu, Jiajie Guan, Philip Gong, Heng Yu, Qiuming
- 机构： Department of Chemical Engineering; State Key Laboratory of Bioreactor Engineering; Joint Graduate Group in Bioengineering; Joint Graduate Group in Bioengineering
- 来源：Proceedings of SPIE - The International Society for Optical Engineering 2010
- 关键词：Finite difference time domain method - Surface scattering - Raman scattering - Gold - Optical properties - Plasmonics - Surface plasmon resonance - Light transmission - Electric fields
- Deletion of poxB, pta, and ackA improves 1,3-propanediol production by Klebsiella pneumoniae被引量：32收藏
- 作者：Lin, Jie Zhang, Yongqiang Xu, Danfeng Xiang, Gang Jia, Zongxiao Fu, Shuilin Gong, Heng
- 机构：E China Univ Sci & Technol
- 来源：APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 2016
- 关键词：1,3-Propanediol Acetate ackA Klebsiella pneumonia poxB pta
- Continuous-Flow Microreactor-Enhanced Clean NAD+ Regeneration for Biosynthesis of 7-Oxo-lithocholic Acid被引量：22收藏
- 作者：Li, Hai-Peng You, Zhi-Neng Liu, Yuan-Yang Zheng, Gao-Wei Gong, Heng Mo, Yiming Zhu, Ning Bai, Yun-Peng Xu, Jian-He
- 机构：East China Univ Sci & Technol;Zhejiang Univ;Nanjing Tech Univ
- 来源：ACS SUSTAINABLE CHEMISTRY & ENGINEERING 2022
- 关键词：Cofactor regeneration Continuous-flow microreactor NAD(P)H oxidases Oxygen transfer Space-time yield Enzyme consumption number Total turnover number
- 豆油对红霉素生物合成的影响及作用机制分析被引量：22收藏
- 作者：卞晨光 宫衡 陈长华 付水林
- 机构：华东理工大学生物反应器工程国家重点实验室
- 来源：《华东理工大学学报（自然科学版）》 2004
- 关键词：豆油 红霉素 丙酰辅酶A合成酶 丙酸激酶 柠檬酸 α-酮戊二酸
- 摘要：在摇瓶培养过程中,培养基中加入豆油可使红霉素的效价从3038U/mL(不加豆油)提高到5221U/mL。但对丙酰辅酶A合成酶及红霉素链霉菌H18丙酸激酶的比活力无显著影响。使用HPLC检测发酵液中α-酮戊二酸(α-KG)...
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- Detection of total protEIn in milk using phosphomolybdic acid-mediated surface-enhanced Raman spectroscopy被引量：20收藏
- 作者：Huang, Yingzhao Gu, Jianming Xiang, Gang Xu, Jiajie Fu, Shuilin Gong, Heng
- 机构：E China Univ Sci & Technol;Shanghai Univ
- 来源：JOURNAL OF RAMAN SPECTROSCOPY 2016
- 关键词：total protEIn casEIn milk phosphomolybdic acid SERS
- 两阶段控制甘油浓度提高1,3-丙二醇发酵水平被引量：19收藏
- 作者：杨树斌 宫衡 付水林
- 机构：华东理工大学生物反应器工程国家重点实验室
- 来源：《华东理工大学学报（自然科学版）》 2006
- 关键词：1 3-丙二醇 甘油浓度 克雷伯氏肺炎杆菌 两阶段 发酵
- 摘要：克雷伯氏菌(K lebsiella pneum on iae)分批发酵生产1,3-丙二醇(1,3-PD),根据菌体生长、产物生成和补料可将发酵过程分成4个阶段。不同阶段控制不同的底物浓度会对菌体生长和产物生成产生不同的影...
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- Improvement of 1,3-propanediol production in Klebsiella pneumoniae by moderate expression of puuC (encoding an aldehyde dehydrogenase)被引量：16收藏
- 作者：Zhu, Chengqian Jiang, Xiao Zhang, Yongqiang Lin, Jie Fu, Shuilin Gong, Heng
- 机构：E China Univ Sci & Technol
- 来源：BIOTECHNOLOGY LETTERS 2015
- 关键词：Aldehyde dehydrogenase 3-Hydroxypropionic acid Klebsiella pneumoniae 1,3-Propanediol puuC
- Influences of 3-hydroxypropionaldehyde and lactate on the production of 1,3-propanediol by Klebsiella pneumoniae被引量：16收藏
- 作者：Zhong, Zhihui Liu, Longfei Zhou, Jiajia Gao, Lirong Xu, Jiajie Fu, Shuilin Gong, Heng
- 机构： State Key Laboratory of Bioreactor Engineering
- 来源：Bioresources and Bioprocessing 2014
- 关键词：Bacteria - Glycerol
- Vector promoters used in Klebsiella pneumoniae被引量：12收藏
- 作者：Jiang, Xiao Zhu, Chengqian Lin, Jie Li, Jingkang Fu, Shuilin Gong, Heng
- 机构：East China Univ Sci & Technol
- 来源：BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY 2016
- 关键词：gene expression Klebsiella pneumoniae LacZ reporter gene metabolic engineering promoter
- In silico identification of potential virulence genes in 1,3-propanediol producer Klebsiella pneumonia被引量：11收藏
- 作者：Gao, L. R. Jiang, X. Fu, S. L. Gong, H.
- 机构：E China Univ Sci & Technol
- 来源：JOURNAL OF BIOTECHNOLOGY 2014
- 关键词：1,3-Propanediol Potential virulence genes In silico Klebsiella pneumonia
- Inactivating NADH:quinone oxidoreductases affects the growth and metabolism of Klebsiella pneumoniae被引量：7收藏
- 作者：Zhang, Lijuan Bao, Wenjing Wei, Renquan Fu, Shuilin Gong, Heng
- 机构：East China Univ Sci & Technol
- 来源：BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY 2018
- 关键词：1,3-propanediol 2,3-butanediol intracellular redox Klebsiella pneumoniae NADH:quinone oxidoreductase
- Deleting pck improves growth and suppresses by-product formation during 1,3-propanediol fermentation by Klebsiella pneumoniae被引量：6收藏
- 作者：Zhang, Yongqiang Jia, Zongxiao Lin, Jie Xu, Danfeng Fu, Shuilin Gong, Heng
- 机构：East China Univ Sci & Technol
- 来源：JOURNAL OF APPLIED MICROBIOLOGY 2017
- 关键词：1 3-propanediol Klebsiella pneumoniae pck phosphoenolpyruvate carboxylation ppc
- High throughput pretreatment of corn stover using compacted biomass with recycled ammonia (COBRA) process被引量：6收藏
- 作者：Zhang, Jian Mohammadi, Maedeh Gong, Heng Hodge, David B. Tumuluru, Jayashankar Sousa, Leonardo da Costa Dale, Bruce Balan, Venkatesh
- 机构：East China Univ Sci & Technol;Univ Houston;Montana State Univ;USDA ARS;Michigan State Univ
- 来源：CHEMICAL ENGINEERING JOURNAL 2025
- 关键词：COBRA pretreatment Ammonia-based pretreatment Lignocellulosic biomass Bioethanol Cellulose crystallinity
- A genome-scale metabolic model of the effect of dissolved oxygen on 1,3-propanediol fermentation by Klebsiella pneumoniae被引量：4收藏
- 作者：Zhang, Yang Yang, Menglei Bao, Yangyang Tao, Weihua Tuo, Jinyou Liu, Boya Gan, Luxi Fu, Shuilin Gong, Heng
- 机构：East China Univ Sci & Technol
- 来源：BIOPROCESS AND BIOSYSTEMS ENGINEERING 2023
- 关键词：1 3-Propanediol Flux balance analysis Genome-scale metabolic model Klebsiella pneumoniae Microaerobic culture
- 克雷伯氏肺炎杆菌生产1,3-丙二醇代谢途径中的酶活变化被引量：2收藏
- 作者：王娅君 赵莉 徐佳杰 付水林 宫衡
- 机构：华东理工大学生物反应器工程国家重点实验室
- 来源：《华东理工大学学报（自然科学版）》 2007
- 关键词：克雷伯氏肺炎杆菌 甘油脱氢酶 1,3-丙二醇氧化还原酶 甘油脱水酶
- 摘要：考察了不同条件下克雷伯氏肺炎杆菌(Klebsiella.pneumoniae)合成1,3-丙二醇(1,3-PD)的3种关键酶(甘油脱氢酶(GDH)、1,3-PD氧化还原酶(PDOR)及甘油脱水酶(GDHz))的表观酶活变...
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- Lignin Removal in Subcellular Location of Poplar Cell Wall During Pretreatment Significantly Impacts Cellulose Digestibility被引量：2收藏
- 作者：Zhang, Jian Kang, Lin Shen, Wei Collings, Cynthia Gong, Heng vander Meulen, Kirk Fox, Brian G. Gilcher, Elise Dumesic, James A. Ding, Shi-You
- 机构：East China Univ Sci & Technol;Michigan State Univ;Michigan State Univ;Chinese Acad Sci;Chinese Acad Sci
- 来源：ACS SUSTAINABLE CHEMISTRY & ENGINEERING 2025
- 关键词：GVL-HCl pretreatment lignin removal subcellular location CBM-GFP binding stimulatedRaman scattering microscopy (SRS) enzyme digestibility
- Acceleration effect of amino acid supplementation on glycerol assimilation by Escherichia coli in minimal medium被引量：2收藏
- 作者：Xiang, Gang Li, Jiang Duan, JiFu Shao, Fei Xu, Jiajie Fu, Shuilin Gong, Heng
- 机构：E China Univ Sci & Technol
- 来源：BIOTECHNOLOGY LETTERS 2013
- 关键词：Amino acids Cell growth Escherichia coli Glycerol Lactose Minimal medium
- Q-Orbitrap-液相色谱串联质谱法测定鸡蛋中甲硝唑及新的代谢物被引量：0收藏
- 作者：秦宇 张申平 王安琪 葛宇 宫衡
- 机构：华东理工大学生物工程学院;上海市质量监督检验技术研究院
- 来源：《分析试验室》 2026
- 关键词：甲硝唑 羧基甲硝唑 鸡蛋 高分辨质谱 液相色谱串联质谱法
- 摘要：建立了液相色谱串联质谱法同时测定鸡蛋中甲硝唑及新代谢物的方法。通过液相色谱串联高分辨质谱进行定性扫描,在鸡蛋中发现一种新的甲硝唑代谢物-羧基甲硝唑。进一步建立了以0.1%(V/V)甲酸乙腈溶液提取,石油醚净化,Water...
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- Moderate overexpression of dhaB through genomic integration improves 1,3-propanediol production by Klebsiella pneumoniae被引量：0收藏
- 作者：Wei, Tingting Wang, Lujie Tang, Yanran Mei, Yuanyuan Chen, Quan Gong, Heng
- 机构：East China Univ Sci & Technol
- 来源：JOURNAL OF APPLIED MICROBIOLOGY 2026
- 关键词：1,3-propanediol Klebsiella pneumoniae genomic integration dhaB moderate overexpression
