成果/Result
- Zebrafish GSDMEb Cleavage-Gated Pyroptosis Drives Septic Acute Kidney Injury In Vivo被引量：88收藏
- 作者：Wang, Zhuang Gu, Zhaoyan Hou, Qing Chen, Weijie Mu, Di Zhang, Yuanxing Liu, Qin Liu, Zhihong Yang, Dahai
- 机构：East China Univ Sci & Technol;Nanjing Univ;Shanghai Engn Res Ctr Maricultured Anim Vaccines;Qingdao Natl Lab Marine Sci & Technol
- 来源：JOURNAL OF IMMUNOLOGY 2020
- leSensing of cytosolic LPS through caspy2 pyrin domain mediates noncanonical inflammasome activation in zbrafish被引量：61收藏
- 作者：Yang, Dahai Zheng, Xin Chen, Shouwen Wang, Zhuang Xu, Wenting Tan, Jinchao Hu, Tianjian Hou, Mingyu Wang, Wenhui Gu, Zhaoyan Wang, Qiyao Zhang, Ruilin Zhang, Yuanxing Liu, Qin
- 机构：East China Univ Sci & Technol;Qingdao Natl Lab Marine Sci & Technol;Shanghai Engn Res Ctr Marine Cultured Anim Vaccin;Shanghai Collaborat Innovat Ctr Biomfg;Fudan Univ
- 来源：NATURE COMMUNICATIONS 2018
- A Water-Soluble, Green-Light Triggered, and Photo-Calibrated Nitric Oxide Donor for Biological Applications被引量：49收藏
- 作者：He, Haihong Xia, Yang Qi, Yingxue Wang, Hong-Yin Wang, Zhuang Bao, Jianming Zhang, Ziqian Wu, Fu-Gen Wang, Haolu Chen, Daijie Yang, Dahai Liang, Xiaowen Chen, Jinquan Zhou, Shengmin Liang, Xin Qian, Xuhong Yang, Youjun
- 机构：East China Univ Sci & Technol;Univ Queensland;East China Normal Univ;Shanghai Jiao Tong Univ;Southeast Univ
- 来源：BIOCONJUGATE CHEMISTRY 2018
- Enhancement of Recombinant Human EPO Production and Sialylation in Chinese Hamster Ovary Cells Through Bombyx mori 30Kc19 Gene Expression被引量：45收藏
- 作者：Wang, Zesong Park, Ju Hyun Park, Hee Ho Tan, Wensong Park, Tai Hyun
- 机构：Seoul Natl Univ;E China Univ Sci & Technol
- 来源：BIOTECHNOLOGY AND BIOENGINEERING 2011
- 关键词：CHO cell EPO 30Kc19 productivity sialylation mitochondrial membrane potential ATP sialyltransferase
- Pyroptosis Mediates Neutrophil Extracellular Trap Formation during Bacterial Infection in Zebrafish被引量：37收藏
- 作者：Chen, Weijie Zhao, Jingjing Mu, Di Wang, Zhuang Liu, Qin Zhang, Yuanxing Yang, Dahai
- 机构：East China Univ Sci & Technol;Qingdao Natl Lab Marine Sci & Technol;Shanghai Engn Res Ctr Maricultured Anim Vaccines
- 来源：JOURNAL OF IMMUNOLOGY 2021
- Neutrophil plays critical role during Edwardsiella piSCIcida immersion infection in zebrafish larvae被引量：34收藏
- 作者：Wang, Zhuang Lin, Lingyun Chen, Weijie Zheng, Xin Zhang, Yuanxing Liu, Qin Yang, Dahai
- 机构：East China Univ Sci & Technol;Zhejiang Inst Freshwater Fisheries;Shanghai Engn Res Ctr Marine Cultured Anim Vaccin
- 来源：FISH & SHELLFISH IMMUNOLOGY 2019
- 关键词：Edwardsiella piSCIcida Zebrafish larvae Neutrophil Bacterial clearance
- Inhibition of HDAC6 With CAY10603 Ameliorates Diabetic Kidney Disease by Suppressing NLRP3 Inflammasome被引量：33收藏
- 作者：Hou, Qing Kan, Shuyan Wang, Zhuang Shi, Jinsong Zeng, Caihong Yang, Dahai Jiang, Song Liu, Zhihong
- 机构：Southeast Univ Sch Med;Nanjing Univ Sch Med;East China Univ Sci & Technol
- 来源：FRONTIERS IN PHARMACOLOGY 2022
- 关键词：connectivity map diabetic nephropathy HDAC6 NLRP3 inflammasome tubular injury
- Identification and functional characterization of EseH, a new effector of the type III secretion system of Edwardsiella piSCIcida被引量：32收藏
- 作者：Hou, Mingyu Chen, Ran Yang, Dahai Nunez, Gabriel Wang, Zhuang Wang, Qiyao Zhang, Yuanxing Liu, Qin
- 机构：East China Univ Sci & Technol;Shanghai Engn Res Ctr Marine Cultured Anim Vaccin;Shanghai Collaborat Innovat Ctr Biomfg;Univ Michigan;Univ Michigan
- 来源：CELLULAR MICROBIOLOGY 2017
- Zebrafish gasdermin E cleavage-engaged pyroptosis by inflammatory and apoptotic caspases被引量：32收藏
- 作者：Chen, Hao Wu, Xiaomin Gu, Zhaoyan Chen, Shouwen Zhou, Xiangshan Zhang, Yuanxing Liu, Qin Wang, Zhuang Yang, Dahai
- 机构：East China Univ Sci & Technol;Southern Marine Sci & Engn Guangdong Lab Zhuhai;Shanghai Engn Res Ctr Maricultured Anim Vaccines
- 来源：DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY 2021
- 关键词：Zebrafish Gsdme Pyroptosis Inflammatory caspases Apoptotic caspases
- Single-Cell Transcriptomic Analysis Reveals Neutrophil as Orchestrator during b-Glucan-Induced Trained Immunity in a Teleost Fish被引量：28收藏
- 作者：Mu, Di Yang, Jin Jiang, Yu Wang, Zhuang Chen, Weijie Huang, Jianchang Zhang, Yuanxing Liu, Qin Yang, Dahai
- 机构：East China Univ Sci & Technol;Southern Marine Sci & Engn Guangdong Lab Zhuhai;Qingdao Natl Lab Marine Sci & Technol;Shanghai Engn Res Ctr Maricultured Anim Vaccines;East China Univ Sci & Technol
- 来源：JOURNAL OF IMMUNOLOGY 2022
- A Photo-triggered and photo-calibrated nitric oxide donor: Rational design, spectral characterizations, and biological applications被引量：27收藏
- 作者：He, Haihong Liu, Yuxin Zhou, Zhongneng Guo, Chunlei Wang, Hong-Yin Wang, Zhuang Wang, Xueli Zhang, Ziqian Wu, Fu-Gen Wang, Haolu Chen, Daijie Yang, Dahai Liang, Xiaowen Chen, Jinquan Zhou, Shengmin Liang, Xin Qian, Xuhong Yang, Youjun
- 机构：East China Univ Sci & Technol;Univ Queensland;East China Normal Univ;Shanghai Jiao Tong Univ;Southeast Univ
- 来源：FREE RADICAL BIOLOGY AND MEDICINE 2018
- 关键词：Nitrc oxide donors Photo-triggered Photo-calibrated Mesenchymal stem cell migration
- Enhancement of recombinant human EPO production and glycosylation in serum-free suspension culture of CHO cells through expression and supplementation of 30Kc19被引量：25收藏
- 作者：Park, Ju Hyun Wang, Zesong Jeong, Hee-Jin Park, Hee Ho Kim, Byung-Gee Tan, Wen-Song Choi, Shin Sik Park, Tai Hyun
- 机构：Seoul Natl Univ;E China Univ Sci & Technol;Myongji Univ
- 来源：APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 2012
- 关键词：CHO cells rHuEPO 30Kc19 protein Productivity Glycosylation
- Preparation of core-shell molecular imprinting polymer for lincomycin A and its application in chromatographic column被引量：25收藏
- 作者：Wang, Zi Cao, Xuejun
- 机构：E China Univ Sci & Technol
- 来源：PROCESS BIOCHEMISTRY 2015
- 关键词：Molecular imprinting Separation Core-shell Chromatography Purification Lincomycin
- Balanced role of T3SS and T6SS in contribution to the full virulence of Edwardsiella piSCIcida被引量：24收藏
- 作者：Hu, Tianjian Chen, Ran Zhang, Lingzhi Wang, Zhuang Yang, Dahai Zhang, Yuanxing Liu, Xiaohong Liu, Qin
- 机构：East China Univ Sci & Technol;Shanghai Engn Res Ctr Maricultured Anim Vaccines;Shanghai Collaborat Innovat Ctr Biomfg
- 来源：FISH & SHELLFISH IMMUNOLOGY 2019
- 关键词：Edwardsiella piSCIcida Infection Live attenuated vaccine T3SS T6SS
- Supramolecular ensembles modified by near-infrared dyes and their biological applications被引量：24收藏
- 作者：Jin, Tongxia Huang, Chusen Cui, Mengyu Yang, Yonghui Wang, Zhuo Zhu, Weiping Qian, Xuhong
- 机构：East China Univ Sci & Technol;Shanghai Normal Univ;Shanghai Normal Univ
- 来源：JOURNAL OF MATERIALS CHEMISTRY B 2020
- 关键词：Diagnosis - Photobleaching - Infrared devices - Supramolecular chemistry - Self assembly
- Application of semi-supervised convolutional neural network regression model based on data augmentation and process spectral labeling in Raman predictive modeling of cell culture processes被引量：22收藏
- 作者：Min, Rui Wang, Zhi Zhuang, Yingping Yi, Xiaoping
- 机构：East China Univ Sci & Technol
- 来源：BIOCHEMICAL ENGINEERING JOURNAL 2023
- 关键词：Semi -supervised learning Convolutional neural network regression Data augmentation Process spectra labeling
- EvpP inhibits neutrophils recruitment via Jnk-caspy inflammasome signaling in vivo被引量：19收藏
- 作者：Tan, Jinchao Yang, Dahai Wang, Zhuang Zheng, Xin Zhang, Yuanxing Liu, Qin
- 机构：East China Univ Sci & Technol;Qingdao Natl Lab Marine Sci & Technol;Shanghai Engn Res Ctr Maricultured Anim Vaccines
- 来源：FISH & SHELLFISH IMMUNOLOGY 2019
- 关键词：Edwardsiella piSCIcida T6SS effector Jnk-caspy inflammasome pathway Neutrophils recruitment
- The Edwardsiella piSCIcida thioredoxin-like protein inhibits ASK1-MAPKs signaling cascades to promote pathogenesis during infection被引量：19收藏
- 作者：Yang, Dahai Liu, Xiaohong Xu, Wenting Gu, Zhaoyan Yang, Cuiting Zhang, Lingzhi Tan, Jinchao Zheng, Xin Wang, Zhuang Quan, Shu Zhang, Yuanxing Liu, Qin
- 机构：East China Univ Sci & Technol;Shanghai Engn Res Ctr Maricultured Anim Vaccines;Qingdao Natl Lab Marine Sci & Technol
- 来源：PLOS PATHOGENS 2019
- Tissue-resident trained immunity in hepatocytes protects against septic liver injury in zebrafish被引量：18收藏
- 作者：Wang, Zhuang Liu, Yuanyuan Hu, Jing You, Xinwei Yang, Jin Zhang, Yuanxing Liu, Qin Yang, Dahai
- 机构：East China Univ Sci & Technol;Southern Marine Sci & Engn Guangdong Lab Zhuhai;Shanghai Engn Res Ctr Maricultured Anim Vaccines
- 来源：CELL REPORTS 2024
- Dysregulated haemolysin promotes bacterial outer membrane vesicles-induced pyroptotic-like cell death in zebrafish被引量：16收藏
- 作者：Wen, Ying Chen, Shouwen Jiang, Zhiwei Wang, Zhuang Tan, Jinchao Hu, Tianjian Wang, Qiyao Zhou, Xiangshan Zhang, Yuanxing Liu, Qin Yang, Dahai
- 机构：East China Univ Sci & Technol;Qingdao Natl Lab Marine Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg;Shanghai Engn Res Ctr Marine Cultured Anim Vaccin
- 来源：CELLULAR MICROBIOLOGY 2019
- 关键词：bacterial outer membrane vesicles Edwardsiella piSCIcida haemolysin pyroptotic-like cell death zebrafish intestinal infection
- Characterization of the inflammasome component SmASC in turbot (Scophthalmus maximus)被引量：13收藏
- 作者：Wang, Wenhui Tan, Jinchao Wang, Zhuang Zhang, Yuanxing Liu, Qin Yang, Dahai
- 机构：East China Univ Sci & Technol;Shanghai Engn Res Ctr Maricultured Anim Vaccines
- 来源：FISH & SHELLFISH IMMUNOLOGY 2020
- 关键词：Scophthalmus maximus SmASC Edwardsiella piSCIcida Immune responses
- Coevolution between marine Aeromonas and phages reveals temporal trade-off patterns of phage resistance and host population fitness被引量：12收藏
- 作者：Xu, Zhenhe Ding, Zihan Shi, Lijia Xie, Yuzhen Zhang, Yuanxing Wang, Zhuang Liu, Qin
- 机构：East China Univ Sci & Technol;Southern Marine Sci & Engn Guangdong Lab Zhuhai;Shanghai Engn Res Ctr Maricultured Anim Vaccines
- 来源：ISME JOURNAL 2023
- Progress and perspective of trained immunity in teleost fish被引量：12收藏
- 作者：You, Xinwei Yang, Jin Wang, Zhuang Wang, Qiyao Liu, Qin Zhang, Yuanxing Wiegertjes, Geert F. Yang, Dahai
- 机构：East China Univ Sci & Technol;Wageningen Univ & Res
- 来源：REVIEWS IN AQUACULTURE 2024
- 关键词：effector cell longer-term protection molecular mechanism teleost fish trained immunity
- Bacterial infection induces pyroptotic signaling-mediated neutrophil extracellular traps (NETs) formation in turbot (Scophthalmus maximus)被引量：9收藏
- 作者：Zhao, Jingjing Chen, Weijie Zhang, Yuanxing Liu, Qin Yang, Dahai Wang, Zhuang
- 机构：East China Univ Sci & Technol;Southern Marine Sci & Engn Guangdong Lab Zhuhai;Shanghai Engn Res Ctr Maricultured Anim Vaccines
- 来源：FISH & SHELLFISH IMMUNOLOGY 2022
- 关键词：Bacterial infection Neutrophil Neutrophils extracellular traps Pyroptosis Turbot
- Mannan-oligosaccharide induces trained immunity activation and alleviates pathological liver injury in turbot (Scophthalmus maximus)被引量：9收藏
- 作者：Wang, Zhuang Hu, Jing Mei, Zhengkang Zhang, Yuanxing Liu, Qin Yang, Dahai
- 机构：East China Univ Sci & Technol;Southern Marine Sci & Engn Guangdong Lab Zhuhai;Shanghai Engn Res Ctr Maricultured Anim Vaccines
- 来源：AQUACULTURE 2024
- 关键词：Mannan-oligosaccharide Trained immunity Liver injury Edwardsiella piSCIcida Turbot
- Dietary supplementation of propolis enhanced the innate immune response against Edwardsiella piSCIcida challenge in turbot (Scophthalmus maximus)被引量：8收藏
- 作者：Wang, Zhuang Mu, Di Jiang, Yu He, Jing Zhang, Yuanxing Yang, Dahai Liu, Qin
- 机构：East China Univ Sci & Technol;Southern Marine Sci & Engn Guangdong Lab Zhuhai;Shanghai Engn Res Ctr Maricultured Anim Vaccines
- 来源：FISH & SHELLFISH IMMUNOLOGY 2022
- 关键词：Propolis Innate immunity Turbot Edwardsiella piSCIcida
- Poly(I:C) induces anti-inflammatory response against secondary LPS challenge in zebrafish larvae被引量：6收藏
- 作者：Wang, Zhuang You, Xinwei Zhang, Yuanxing Liu, Qin Yang, Dahai
- 机构：East China Univ Sci & Technol;Southern Marine Sci & Engn Guangdong Lab Zhuhai;Shanghai Engn Res Ctr Maricultured Anim Vaccines;East China Univ Sci & Technol
- 来源：FISH & SHELLFISH IMMUNOLOGY 2024
- 关键词：Poly(I:C) Macrophages Anti -inflammation Septic shock Zebrafish larvae
- ScRNA-seq reveals trained immunity-engaged Th17 cell activation against Edwardsiella piSCIcida-induced intestinal inflammation in teleost被引量：5收藏
- 作者：Yang, Jin Cui, Shu Shao, Boning Zhao, Yanbo Wang, Zhuang Liu, Qin Zhang, Yuanxing Yang, Dahai
- 机构：East China Univ Sci & Technol;Qingdao Marine Sci & Technol Ctr;Southern Marine Sci & Engn Guangdong Lab Zhuhai;Shanghai Engn Res Ctr Maricultured Anim Vaccines
- 来源：MICROBIOLOGICAL RESEARCH 2024
- 关键词：Edwardsiella piSCIcida beta-Glucan Th17 cells Intestinal inflammation Teleost
- PurA facilitates Edwardsiella piSCIcida to escape NF-KB signaling activation被引量：5收藏
- 作者：Hu, Feizi Zhang, Yuanxing Liu, Qin Wang, Zhuang
- 机构：East China Univ Sci & Technol;Southern Marine Sci & Engn Guangdong Lab Zhuhai;Shanghai Engn Res Ctr Maricultured Anim Vaccines
- 来源：FISH & SHELLFISH IMMUNOLOGY 2022
- 关键词：Edwardsiella piSCIcida Adenylosuccinate synthase NF-KB singlaing Immuno-evasion
- TLR5b-mediated NF-KB activation promotes neutrophil recruitment to defense Edwardsiella piSCIcida infection in zebrafish被引量：5收藏
- 作者：Hu, Feizi Wang, Zhuang Zhang, Yuanxing Yang, Dahai Liu, Qin
- 机构：East China Univ Sci & Technol;Southern Marine Sci & Engn Guangdong Lab Zhuhai;Shanghai Engn Res Ctr Maricultured Anim Vaccines
- 来源：AQUACULTURE 2023
- 关键词：Edwardsiella piSCIcida NF-KB TLR5b Neutrophil Zebrafish
