成果/Result
- Smart plant-wearable biosensor for in-situ pesticide analysis被引量：195收藏
- 作者：Zhao, Fengnian He, Jianwei Li, Xunjia Bai, Yunpeng Ying, Yibin Ping, Jianfeng
- 机构：Zhejiang Univ;East China Univ Sci & Technol;Zhejiang A&F Univ
- 来源：BIOSENSORS & BIOELECTRONICS 2020
- 关键词：Wearable biosensor Graphene In-situ analysis Pesticide residue Precision agriculture
- Preparation of Structurally Diverse Chiral Alcohols by Engineering Ketoreductase CgKR1被引量：82收藏
- 作者：Zheng, Gao-Wei Liu, Yuan-Yang Chen, Qi Huang, Lei Yu, Hui-Lei Lou, Wen-Yong Li, Chun-Xiu Bai, Yun-Peng Li, Ai-Tao Xu, Jian-He
- 机构：East China Univ Sci & Technol;South China Univ Technol;Max Planck Inst Kohlenforsch
- 来源：ACS CATALYSIS 2017
- 关键词：asymmetric reduction ketoreductase chiral alcohol protein engineering substrate specificity biocatalysis
- Biodegradation of Structurally Diverse Phthalate Esters by a Newly Identified Esterase with Catalytic Activity toward Di(2-ethylhexyl) Phthalate被引量：75收藏
- 作者：Huang, Han Zhang, Xiao-Yan Chen, Tian-Lei Zhao, Yu-Lian Xu, Dian-Sheng Bai, Yun-Peng
- 机构：East China Univ Sci & Technol
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2019
- 关键词：Gordonia polyisoprenivorans esterase bis(2-ethylhexyl) phthalate phthalate esters biodegradation
- Bioremediation of phenolic pollutants by algae-current status and challenges被引量：60收藏
- 作者：Wu, Ping Zhang, Zhaofei Luo, Yeling Bai, Yunpeng Fan, Jianhua
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：BIORESOURCE TECHNOLOGY 2022
- 关键词：Algae Phenolic pollutants Removal mechanisms Industrial value
- Improved synthesis of 2,5-bis(hydroxymethyl)furan from 5-hydroxymethylfurfural using acclimatized whole cells entrapped in calcium alginate被引量：54收藏
- 作者：Xu, Zhong-Hua Cheng, Ai-Di Xing, Xu-Pu Zong, Min-Hua Bai, Yun-Peng Li, Ning
- 机构：South China Univ Technol;East China Univ Sci & Technol
- 来源：BIORESOURCE TECHNOLOGY 2018
- 关键词：Biocatalysis Biobased platform chemicals Immobilization Reduction Whole cells
- Confining Enzyme Clusters in Bacteriophage P22 Enhances Cofactor Recycling and Stereoselectivity for Chiral Alcohol Synthesis被引量：40收藏
- 作者：Zhang, Yan-Qing Feng, Tao-Tao Cao, Yu-Fei Zhang, Xiao-Yan Wang, Tao Nina, Mario Roque Huanca Wang, Li-Cheng Yu, Hui-Lei Xu, Jian-He Ge, Jun Bai, Yun-Peng
- 机构：East China Univ Sci & Technol ECUST;Tsinghua Univ;Tsinghua Shenzhen Int Grad Sch;Shenzhen Bay Lab;Tsinghua Univ
- 来源：ACS CATALYSIS 2021
- 关键词：enzyme cluster enzymatic catalysis cofactor recycling confinement effects asymmetric reduction
- A novel D-mandelate dehydrogenase used in three-enzyme cascade reaction for highly efficient synthesis of non-natural chiral amino acids被引量：40收藏
- 作者：Fan, Chang-Wei Xu, Guo-Chao Ma, Bao-Di Bai, Yun-Peng Zhang, Jie Xu, Jian-He
- 机构：E China Univ Sci & Technol
- 来源：JOURNAL OF BIOTECHNOLOGY 2015
- 关键词：D-Mandelate dehydrogenase L-Phenylglycine Asymmetric synthesis Cascade reaction Process optimization
- Transcription Factor Engineering for High-Throughput Strain Evolution and Organic Acid Bioproduction: A Review被引量：37收藏
- 作者：Li, Jia-Wei Zhang, Xiao-Yan Wu, Hui Bai, Yun-Peng
- 机构：East China Univ Sci & Technol
- 来源：FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY 2020
- 关键词：transcription factor biosensor metabolic engineering synthetic biology organic acid high-throughput screening
- Microfluidic reactor with immobilized enzyme-from construction to applications: A review被引量：31收藏
- 作者：Zhang, Han Bai, Yunpeng Zhu, Ning Xu, Jianhe
- 机构：East China Univ Sci & Technol;Nanjing Tech Univ
- 来源：CHINESE JOURNAL OF CHEMICAL ENGINEERING 2021
- 关键词：Microfluidic immobilized enzyme reactor Immobilization strategies Biocatalysis Bioconversion Bioanalysis
- Flocculation of Chlamydomonas reinhardtii with Different Phenotypic Traits by Metal Cations and High pH被引量：31收藏
- 作者：Fan, Jianhua Zheng, Lvhong Bai, Yunpeng Saroussi, Shai Grossman, Arthur R.
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Carnegie Inst Sci
- 来源：FRONTIERS IN PLANT SCIENCE 2017
- 关键词：flocculation cell wall deficient Chlamydomonas multivalent metal ions microalgae pH algal biotechnology
- Efficient Stereoselective Synthesis of Structurally Diverse γ- and δ-Lactones Using an Engineered Carbonyl Reductase被引量：26收藏
- 作者：Chen, Meng Zhang, Xiao-Yan Xing, Chen-Guang Zhang, Chao Zheng, Yu-Cong Pan, Jiang Xu, Jian-He Bai, Yun-Peng
- 机构：East China Univ Sci & Technol;Xiamen Oamic Biotech Co Ltd
- 来源：CHEMCATCHEM 2019
- 关键词：Asymmetric reduction directed evolution chiral lactones carbonyl reductase biocatalysis
- An engineered quorum-sensing-based whole-cell biosensor for active degradation of organophosphates被引量：25收藏
- 作者：He, Jianwei Zhang, Xiaoyan Qian, Yuanyi Wang, Qiyao Bai, Yunpeng
- 机构：East China Univ Sci & Technol
- 来源：BIOSENSORS & BIOELECTRONICS 2022
- 关键词：Whole-cell biosensor Synthetic biology Genetic circuits Quorum sensing Degradation
- Combinatorial Evolution of Phosphotriesterase Toward a Robust Malathion Degrader by Hierarchical Iteration Mutagenesis被引量：25收藏
- 作者：Luo, Xiao-Jing Zhao, Jian Li, Chun-Xiu Bai, Yun-Peng Reetz, Manfred T. Yu, Hui-Lei Xu, Jian-He
- 机构：East China Univ Sci & Technol;Max Planck Inst Kohlenforsch;Philipps Univ Marburg
- 来源：BIOTECHNOLOGY AND BIOENGINEERING 2016
- 关键词：biocatalysis directed evolution DNA shuffling malathion phosphotriesterase
- Engineering Transcription Factor XylS for Sensing Phthalic Acid and Terephthalic Acid: An Application for Enzyme Evolution被引量：23收藏
- 作者：Li, Jiawei Nina, Mario Roque Huanca Zhang, Xiaoyan Bai, Yunpeng
- 机构：East China Univ Sci & Technol
- 来源：ACS SYNTHETIC BIOLOGY 2022
- 关键词：biosensor transcription factor engineering phthalic acid terephthalic acid enzyme evolution biodegradation
- Continuous-Flow Microreactor-Enhanced Clean NAD+ Regeneration for Biosynthesis of 7-Oxo-lithocholic Acid被引量：22收藏
- 作者：Li, Hai-Peng You, Zhi-Neng Liu, Yuan-Yang Zheng, Gao-Wei Gong, Heng Mo, Yiming Zhu, Ning Bai, Yun-Peng Xu, Jian-He
- 机构：East China Univ Sci & Technol;Zhejiang Univ;Nanjing Tech Univ
- 来源：ACS SUSTAINABLE CHEMISTRY & ENGINEERING 2022
- 关键词：Cofactor regeneration Continuous-flow microreactor NAD(P)H oxidases Oxygen transfer Space-time yield Enzyme consumption number Total turnover number
- Asymmetric bioreduction of keto groups of 4-and 5-Oxodecanoic acids/esters with a new carbonyl reductase被引量：19收藏
- 作者：Zhang, Chao Pan, Jiang Li, Chun-Xiu Bai, Yun-Peng Xu, Jian-He
- 机构：East China Univ Sci & Technol
- 来源：CATALYSIS COMMUNICATIONS 2017
- 关键词：4-Oxodecanoic acid 5-Oxodecanoic acid (R)-gamma-Decalactone (R)-delta-Decalactone Carbonyl reductase Asymmetric reduction
- Continuous-flow enzymatic synthesis of chiral lactones in a three-dimensional microfluidic reactor被引量：18收藏
- 作者：Deng, Xuelei Fan, Meng Wu, Miao Zhang, Xiaoyan Cheng, Ya Xia, Jianye Zhuang, Yingping Zhu, Weiping Qian, Xuhong Bai, Yunpeng
- 机构：East China Univ Sci & Technol;East China Normal Univ;Chinese Acad Sci
- 来源：CHINESE CHEMICAL LETTERS 2024
- 关键词：Continuous-flow Flow chemistry Microreactor Biocatalysis Carbonyl reductase Asymmetric reduction
- Efficient Degradation of Malathion in the Presence of Detergents Using an Engineered Organophosphorus Hydrolase Highly. Expressed by Pichia pastoris without Methanol Induction被引量：17收藏
- 作者：Bai, Yun-Peng Luo, Xiao-Jing Zhao, Yu-Lian Li, Chun-Xiu Xu, Dian-Sheng Xu, Jian-He
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2017
- 关键词：biodegradation Pichia pastoris organophosphorus hydrolase extracellular expression malathion
- Cross-linked enzyme-polymer conjugates with excellent stability and detergent-enhanced activity for efficient organophosphate degradation被引量：17收藏
- 作者：Cheng, Huan Zhao, Yu-Lian Luo, Xiao-Jing Xu, Dian-Sheng Cao, Xun Xu, Jian-He Dai, Qing Zhang, Xiao-Yan Ge, Jun Bai, Yun-Peng
- 机构：East China Univ Sci & Technol;Tsinghua Univ;Natl Ctr Nanosci & Technol
- 来源：BIORESOURCES AND BIOPROCESSING 2018
- 关键词：Organophosphate Organophosphate hydrolase Immobilization Biodegradation Enzyme-polymer conjugates Pluronic F127
- A novel dihydroxylated derivative of artemisinin from microbial transformation被引量：17收藏
- 作者：Zhan, Yulian Wu, Yunshan Xu, Fangfang Bai, Yunpeng Guan, Yezhi Williamson, John S. Liu, Bo
- 机构：Guilin Univ Elect Technol;East China Univ Sci & Technol;Guangzhou Univ Chinese Med;Univ Mississippi;Guangzhou Univ Chinese Med
- 来源：FITOTERAPIA 2017
- 关键词：Microbial transformation Artemisinin Cunninghamella elegans Antimalarial drugs
- Continuous-flow synthesis of polysubstituted γ -butyrolactones via enzymatic cascade catalysis被引量：16收藏
- 作者：Chu, Liliang Zhang, Xiaoyan Li, Jianing Deng, Xuelei Wu, Miao Cheng, Ya Zhu, Weiping Qian, Xuhong Bai, Yunpeng
- 机构：East China Univ Sci & Technol;East China Normal Univ
- 来源：CHINESE CHEMICAL LETTERS 2024
- 关键词：Enzyme catalysis Cascade catalysis Directed evolution Continuous-flow gamma -Butyrolactones
- Stereoselective synthesis of chiral δ-lactones via an engineered carbonyl reductase被引量：14收藏
- 作者：Wang, Tao Zhang, Xiao-Yan Zheng, Yu-Cong Bai, Yun-Peng
- 机构：East China Univ Sci & Technol
- 来源：CHEMICAL COMMUNICATIONS 2021
- 关键词：Stereoselectivity - Cost effectiveness - Substrates - Esters
- Direct Access to Medium-Chain α,ω-Dicarboxylic Acids by Using a Baeyer-Villiger Monooxygenase of Abnormal Regioselectivity被引量：14收藏
- 作者：Yu, Jia-Mei Liu, Yuan-Yang Zheng, Yu-Cong Li, Hao Zhang, Xiao-Yan Zheng, Gao-Wei Li, Chun-Xiu Bai, Yun-Peng Xu, Jian-He
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：CHEMBIOCHEM 2018
- 关键词：biocatalysis dicarboxylic acids oxidation regioselectivity renewable resources
- Micro/nano flow chemistry by Beyond Limits Manufacturing被引量：13收藏
- 作者：Liu, Peiwen Zhao, Fang Zhang, Jing Bai, Yunpeng Ye, Jinxing Bao, Bo Zhou, Xinggui Zhang, Li Zhou, Changlu Yu, Xinhai Zuo, Peng Xia, Jianye Cen, Lian Yang, Yangyang Shi, Guoyue Xu, Lin Zhu, Weiping Xu, Yufang Qian, Xuhong
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;Guangdong Univ Technol;East China Univ Sci & Technol
- 来源：CHINESE CHEMICAL LETTERS 2024
- 关键词：Beyond Limits Manufacturing Flow chemistry Pharmaceutical manufacturing Microreactor
- Enzyme-photo-coupled catalysis in gas-sprayed microdroplets被引量：13收藏
- 作者：Bai, Yunxiu Luan, Pengqian Bai, Yunpeng Zare, Richard N. Ge, Jun
- 机构：Tsinghua Univ;Shenzhen Bay Lab;East China Univ Sci & Technol ECUST;Stanford Univ;Tsinghua Shenzhen Int Grad Sch
- 来源：CHEMICAL SCIENCE 2022
- 关键词：Energy utilization - Enzyme activity - Large scale systems - Solar energy
- Paper-Based Enzymatic Colorimetric Assay for Rapid Malathion Detection被引量：13收藏
- 作者：Li, Jian-Hui Deng, Xue-Lei Zhao, Yu-Lian Zhang, Xiao-Yan Bai, Yun-Peng
- 机构：Ocean Univ China;East China Univ Sci & Technol
- 来源：APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY 2021
- 关键词：Enzyme immobilization Paper-based biosensor Malathion detection Polymer– enzyme conjugate Organophosphate hydrolase
- Reshaping the active pocket of promiscuous lactonases for degrading bulky organophosphate flame retardants被引量：12收藏
- 作者：Zhang, Yuanyuan Zhang, Xiaoyan Cheng, Huan Nina, Mario Roque Huanca Ge, Jun Bai, Yunpeng
- 机构：East China Univ Sci & Technol;Tsinghua Univ
- 来源：CHEMICAL COMMUNICATIONS 2021
- 关键词：Flame retardants
- Using algae cells to drive cofactor regeneration and asymmetric reduction for the synthesis of chiral chemicals被引量：11收藏
- 作者：Zheng, Lvhong Zhang, Xiaoyan Bai, Yunpeng Fan, Jianhua
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS 2018
- 关键词：Algae biocatalyst Chiral alcohols Biocatalysis Cell factory Microalgae Artificial modification
- Coimmobilized Dual Enzymes in a Continuous Flow Reactor for the Efficient Synthesis of Optically Pure γ/δ-Lactones被引量：10收藏
- 作者：Yuan, Pengyu Wang, Qing Deng, Xuelei Zhang, Xiaoyan Fan, Daidi Bai, Yunpeng
- 机构：East China Univ Sci & Technol;Northwest Univ
- 来源：ACS APPLIED MATERIALS & INTERFACES 2024
- 关键词：enzyme catalysis enzyme immobilization cofactorrecycling continuous-flow microreactor
- Improved efficiency of a novel methyl parathion hydrolase using consensus approach被引量：10收藏
- 作者：Liu, Xu-Yun Chen, Fei-Fei Li, Chun-Xiu Luo, Xiao-Jing Chen, Qi Bai, Yun-Peng Xu, Jian-He
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Natl Engn Res Ctr Miniaturized Detect Syst
- 来源：ENZYME AND MICROBIAL TECHNOLOGY 2016
- 关键词：Biodegradation Organophosphorus pesticides Methyl parathion hydrolase Consensus approach Site-directed mutagenesis Catalytic efficiency
