成果/Result
- Eu(OTf)3-Catalyzed Formal Dipolar [4π+2σ] Cycloaddition of Bicyclo-[1.1.0]butanes with Nitrones: Access to Polysubstituted 2-Oxa-3-azabicyclo[3.1.1]heptanes被引量：113收藏
- 作者：Zhang, Jian Su, Jia-Yi Zheng, Hanliang Li, Hao Deng, Wei-Ping
- 机构：Zhejiang Normal Univ;East China Univ Sci & Technol
- 来源：ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 2024
- 关键词：Bicyclic Compounds Bioisosteres Dipolar Cycloaddition Bicyclo[1.1.0]butanes Strained Molecules
- Organocatalytic Enantioselective Direct Additions of Aldehydes to 4-Vinylpyridines and Electron-Deficient Vinylarenes and ThEIr Synthetic Applications被引量：87收藏
- 作者：Wang, Sinan Li, Xiangmin Liu, Hongwei Xu, Li Zhuang, Jinchen Li, Jian Li, Hao Wang, Wei
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol;Univ New Mexico
- 来源：JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 2015
- 关键词：Ethers - Synthesis (chemical) - Catalysis - Enantioselectivity - Chemical activation - Pyridine
- An Organocatalytic Cascade Approach toward Polysubstituted Quinolines and Chiral 1,4-Dihydroquinolines-Unanticipated Effect of N-Protecting Groups被引量：80收藏
- 作者：Zhang, Xinshuai Song, Xixi Li, Hao Zhang, Shilei Chen, Xiaobei Yu, Xinhong Wang, Wei
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol;Univ New Mexico
- 来源：ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 2012
- 关键词：1 4-dihydroquinolines cascade reactions divergent synthesis organocatalysis quinolines
- Photocatalytic C-H silylation of heteroarenes by using trialkylhydrosilanes被引量：76收藏
- 作者：Liu, Shihui Pan, Peng Fan, Huaqiang Li, Hao Wang, Wei Zhang, Yongqiang
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Univ Arizona
- 来源：CHEMICAL SCIENCE 2019
- 关键词：Chemical stability
- Cycloaddition of trifluoromethyl ketimines with 2-alkenyl azaarenes through selective C-F bond cleavage of CF3被引量：74收藏
- 作者：Fu, Yiwei Qin, Cong Zhang, Zhiqiang Shi, Haoyu Zhao, Jianbo Gong, Xueqing Shi, Lei Li, Hao
- 机构： State Key Laboratory of Bioreactor Engineering; Key Laboratory for Advanced Materials; Huabao Flavours and Fragrances Co. Ltd.
- 来源：Organic Chemistry Frontiers 2021
- 关键词：Chemical bonds
- A Strategy Enabling Enantioselective Direct Conjugate Addition of Inert Aryl Methane Nucleophiles to Enals with a Chiral Amine Catalyst under Mild Conditions被引量：67收藏
- 作者：Li, Tengfei Zhu, Jin Wu, Deyan Li, Xiangmin Wang, Sinan Li, Hao Li, Jian Wang, Wei
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol;Univ New Mexico
- 来源：CHEMISTRY-A EUROPEAN JOURNAL 2013
- 关键词：aryl methane enals iminium catalysis Michael addition organocatalysis
- Asymmetric synthesis of isoquinolinonaphthyridines catalyzed by a chiral Br?nsted acid被引量：63收藏
- 作者：Li, Jianjun Fu, Yiwei Qin, Cong Yu, Yang Li, Hao Wang, Wei
- 机构： State Key Laboratory of Bioengineering Reactor; Department of Chemistry and Chemical Biology
- 来源：Organic and Biomolecular Chemistry 2017
- 关键词：Cyclization
- Access to spiro-bicyclo[2.1.1]hexanes via BF3·Et2O-catalyzed formal [2π + 2σ] cycloaddition of bicyclo[1.1.0]butanes with benzofuran-derived oxa(aza)dienes被引量：55收藏
- 作者：Su, Jia-Yi Zhang, Jian Xin, Zhi-Yun Li, Hao Zheng, Hanliang Deng, Wei-Ping
- 机构： State Key Laboratory of Bioreactor Engineering; Key Laboratory of the Ministry of Education for Advanced Catalysis Materials
- 来源：Organic Chemistry Frontiers 2024
- 关键词：Butane - Catalysis - Olefins
- Construction of Chiral Bridged Tricyclic Benzopyrans: Enantioselective Catalytic Diels-Alder Reaction and a One-Pot Reduction/Acid-Catalyzed Stereoselective Cyclization被引量：48收藏
- 作者：Song, Aiguo Zhang, Xinshuai Song, Xixi Chen, Xiaobei Yu, Chenguang Huang, He Li, Hao Wang, Wei
- 机构：Univ New Mexico;E China Univ Sci & Technol;E China Univ Sci & Technol
- 来源：ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 2014
- 关键词：cyclization decarboxylation heterocycles organocatalysis synthetic methods
- Ligand-free Cu-catalyzed [3+2] cyclization for the synthesis of pyrrolo[1,2-a]quinolines with ambient air as a terminal oxidant被引量：47收藏
- 作者：Yu, Yang Liu, Yuan Liu, Aoxia Xie, Hexin Li, Hao Wang, Wei
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Univ New Mexico
- 来源：ORGANIC & BIOMOLECULAR CHEMISTRY 2016
- 关键词：Catalysis - Chelation - Ligands - Oxidants
- FeCl3 promoted highly regioselective [3 + 2] cycloaddition of dimethyl 2-vinyl and aryl cyclopropane-1,1-dicarboxylates with aryl isothiocyanates被引量：46收藏
- 作者：Wang, Huina Yang, Wei Liu, Hong Wang, Wei Li, Hao
- 机构： Shanghai Institute of Materia Medica; School of Pharmacy
- 来源：Organic and Biomolecular Chemistry 2012
- 关键词：Chlorine compounds - Regioselectivity
- In(OTf)3-Catalyzed (3+3) Dipolar Cyclization of Bicyclo[1.1.0]butanes with N-Nucleophilic 1,3-Dipoles: Access to 2,3-Diazabicyclo[3.1.1]heptanes, 2,3-Diazabicyclo[3.1.1]heptenes, and Enantiopure 2-Azabicyclo[3.1.1]heptanes被引量：40收藏
- 作者：Zhang, Jian Su, Jia-Yi Zheng, Hanliang Li, Hao Deng, Wei-Ping
- 机构：Zhejiang Normal Univ;East China Univ Sci & Technol
- 来源：ACS CATALYSIS 2024
- 关键词：bridged bicyclic scaffolds strained molecules dipolar cyclization bicyclo[1.1.0]butanes asymmetriccatalysis
- Rational Design of an Ultrasensitive and Highly Selective Chemodosimeter by a Dual Quenching Mechanism for CystEIne Based on a Facile Michael-Transcyclization Cascade Reaction被引量：37收藏
- 作者：Li, Xiangmin Zheng, Yongjun Tong, Hongjuan Qian, Rui Zhou, Lin Liu, Guixia Tang, Yun Li, Hao Lou, Kaiyan Wang, Wei
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Univ New Mexico
- 来源：CHEMISTRY-A EUROPEAN JOURNAL 2016
- 关键词：cascade reactions chemodosimeter click chemistry cystEIne fluorescent probes
- Total Synthesis of Polyene Natural Product Dihydroxerulin by Mild Organocatalyzed Dehydrogenation of Alcohols被引量：29收藏
- 作者：Xie, Hexin Zhang, Shilei Li, Hao Zhang, Xinshuai Zhao, Sihan Xu, Zian Song, Xixi Yu, Xinhong Wang, Wei
- 机构：Univ New Mexico;E Univ Sci & Technol
- 来源：CHEMISTRY-A EUROPEAN JOURNAL 2012
- 关键词：dehydrogenation dihydroxerulin enals organocatalysis oxidative enamine catalysis polyenes
- Cocrystals of Oxymatrine: Reducing Hygroscopicity and Affecting the Dissolution Rate被引量：25收藏
- 作者：Qi, Ming-Hui Li, Heng Zhu, Bin Hong, Minghuang Ren, Guo-Bin
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：CRYSTAL GROWTH & DESIGN 2021
- 关键词：Dissolution - Hydrogen bonds - Metabolism
- Transition-metal-free synthesis of indolizines via [3+2]-annulation from α-bromoenals and 2-substituted azaarenes被引量：20收藏
- 作者：Liu, Yuan Yu, Yang Fu, Yiwei Liu, Yonghai Shi, Lei Li, Hao Wang, Wei
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Firmenich Aromat China Co Ltd;Univ New Mexico
- 来源：ORGANIC CHEMISTRY FRONTIERS 2017
- 关键词：Addition reactions
- Continuous Flow Process for the Synthesis of Betahistine via Aza-Michael-Type Reaction in Water被引量：16收藏
- 作者：Sun, Maolin Yang, Jingxin Fu, Youtian Liang, Chaoming Li, Hong Yan, Guoming Yin, Chao Yu, Wei Ma, Yueyue Cheng, Ruihua Ye, Jinxing
- 机构：East China Univ Sci & Technol;Guangdong Univ Technol;Shanghai Zhongxi Sunve Pharmaceut Co Ltd;East China Univ Sci & Technol
- 来源：ORGANIC PROCESS RESEARCH & DEVELOPMENT 2021
- 关键词：betahistine continuous flow process intensification energy-efficient environmentally friendly
- Alkenylazaarenes as dipolarophiles in 1,3-dipolar cycloaddition of nitrones: regioselectivity-switchable and highly diastereoselective synthesis of multisubstituted isoxazolidines被引量：16收藏
- 作者：Tong, Mengchao Zhang, Yong Qin, Cong Fu, Yiwei Liu, Yonghai Li, Hao Wang, Wei
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Univ New Mexico
- 来源：ORGANIC CHEMISTRY FRONTIERS 2018
- 关键词：Microwave irradiation - Stereoselectivity
- Fragrance-containing microcapsules based on interfacial thiol-ene polymerization被引量：14收藏
- 作者：Liao, Ziyang Xue, Daquan Li, Hao Shi, Lei
- 机构：East China Univ Sci & Technol;Shanghai Yilian Chem & Hitech Co Ltd;Firmenich Aromat China Co Ltd
- 来源：JOURNAL OF APPLIED POLYMER SCIENCE 2016
- 关键词：applications kinetics membranes
- A general strategy for construction of a difluoromethyl compound library and its application in synthesis of pseudopeptides bearing a terminal difluoromethyl group被引量：12收藏
- 作者：Wu, Jingjing Cao, Song Liu, Nianjin Shen, Li Yu, Jinlong Zhang, Jian Li, Hui Qian, Xuhong
- 机构：E China Univ Sci & Technol
- 来源：ORGANIC & BIOMOLECULAR CHEMISTRY 2010
- Direct Transformation of Simple Enals to 3,4-Disubstituted Benzaldehydes under Mild Reaction Conditions via an Organocatalytic Regio- and Chemoselective Dimerization Cascade被引量：11收藏
- 作者：Song, Xixi Zhang, Xinshuai Zhang, Shilei Li, Hao Wang, Wei
- 机构：E China Univ Sci & Technol;Univ New Mexico
- 来源：CHEMISTRY-A EUROPEAN JOURNAL 2012
- 关键词：arenes aromatization cascade reactions dimerization organocatalysis
- Copper Promoted Aerobic Oxidative C(sp3)-C(sp3) Bond Cleavage of N-(2-(Pyridin-2-yl)-ethyl)anilines被引量：9收藏
- 作者：Yu, Yang Zhang, Yong Sun, Chengyu Shi, Lei Wang, Wei Li, Hao
- 机构：East China Univ Sci & Technol;Univ Arizona;Firmenich Aromat China Co Ltd
- 来源：JOURNAL OF ORGANIC CHEMISTRY 2020
- 关键词：Copper - Stem cells
- Transition-metal-free access to benzyl ethers via aerobic cross-dehydrogenative coupling of benzylic C(sp3)-H bonds with alcohols被引量：8收藏
- 作者：Zhang, Xiao Li, Wenjie Yu, Yang Luo, Min Bai, Hua Shi, Lei Li, Hao
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Dohler Food & Beverage Ingredients Shanghai Co Ltd
- 来源：GREEN CHEMISTRY 2024
- 关键词：Ethers - Molecular oxygen - Oxidants - Potassium hydroxide
- An Unconventional Redox Cross Claisen Condensation-Aromatization of 4-Hydroxyprolines with Ketones被引量：8收藏
- 作者：Tang, Mi Sun, Rengwei Li, Hao Yu, Xinhong Wang, Wei
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Univ New Mexico
- 来源：JOURNAL OF ORGANIC CHEMISTRY 2017
- 关键词：Propionic acid - Cyclization - Condensation - Reaction intermediates - Synthesis (chemical) - Condensation reactions - Carboxylation - Esters - Redox reactions
- An efficient three-component domino synthesis of difluoromethyl-containing 1,4-dihydropyridines under solvent and catalyst free conditions被引量：8收藏
- 作者：Li Hui Yu JinLong Cao Song Shen Li Wu MingXi Cheng JianHang Qian XuHong
- 机构：E China Univ Sci & Technol
- 来源：SCIENCE CHINA-CHEMISTRY 2010
- 关键词：three-component difluoromethyl 1,4-dihydropyridines ethyl difluoroacetoacetate
- Transition-metal-free decarbonylative alkylation towards N-aryl α-hydroxy amides via triple C-C bond cleavages and thEIr selective deuteration被引量：6收藏
- 作者：Sun, Chengyu Yu, Yang Zhang, Xiao Liu, Yonghai Sun, Chengtao Kai, Guoyin Shi, Lei Li, Hao
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Zhejiang Chinese Med Univ;Huabao Flavours & Fragrances Co Ltd
- 来源：ORGANIC CHEMISTRY FRONTIERS 2021
- 关键词：Transition metals - Deuterium - Amides
- Access to α-Hydroxy Amides via a Practical Metal-Free "One-Pot" Tandem Reaction Involving Aerobic C(sp3)-H Hydroxylation and C(sp2)-C(sp3) Cleavage被引量：6收藏
- 作者：Zhang, Xiao Yu, Yang Li, Wenjie Shi, Lei Li, Hao
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Dohler Food & Beverage Ingredients Shanghai Co Ltd
- 来源：JOURNAL OF ORGANIC CHEMISTRY 2022
- 关键词：Amides
- Primary amine catalyzed diastereo- and enantioselective Michael reaction of thiazolones and α,β-unsaturated ketones被引量：6收藏
- 作者：Lu, Min Li, Hong Zou, Chuncheng Li, Jianchang Liu, Chengyu Sun, Maolin Ma, Yueyue Cheng, Ruihua Ye, Jinxing
- 机构：East China Univ Sci & Technol
- 来源：ORGANIC & BIOMOLECULAR CHEMISTRY 2019
- 关键词：Addition reactions - Additives - Amines - Enantioselectivity - Ketones - Catalysis
- Palladium-catalyzed allylic alkylation enabled by ketone umpolung via Pudovik addition/[1,2]-phospha-Brook rearrangement被引量：5收藏
- 作者：Zhang, Jian Su, Jia-Yi Liu, Yang-Zi Li, Hao Wang, Quannan Deng, Wei-Ping
- 机构：Zhejiang Normal Univ;East China Univ Sci & Technol
- 来源：SCIENCE CHINA-CHEMISTRY 2023
- 关键词：palladium umpolung allylic alkylation Pudovik addition [1,2]-phospha-Brook rearrangement
- Design, synthesis, and biological antitumor evaluation of tetrahydroisoquinoline derivatives被引量：4收藏
- 作者：Pang, Can Zhao, Jianbo Zhang, Shuai Chen, Jiayu Zeng, Xiu Li, Hao
- 机构：East China Univ Sci & Technol; East China Univ Sci & Technol
- 来源：BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 2024
- 关键词：Antitumor In vitro Quaternary ammonium salt Synthesis Tetrahydroisoquinoline
