成果/Result
- Organocatalysis: asymmetric cascade reactions catalysed by chiral secondary amines被引量：482收藏
- 作者：Yu, Xinhong Wang, Wei
- 机构：Univ New Mexico;E China Univ Sci & Technol
- 来源：ORGANIC & BIOMOLECULAR CHEMISTRY 2008
- 关键词：Rate constants - Amines
- Fluorescent Probes for the Detection of Hydrogen Sulfide in Biological Systems被引量：269收藏
- 作者：Xuan, Weimin Sheng, Chunquan Cao, Yanting He, Wenhan Wang, Wei
- 机构：Second Mil Med Univ;Univ New Mexico;E China Univ Sci & Technol
- 来源：ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 2012
- 关键词：azides fluorescEIn fluorescent probes hydrogen sulfide rhodamines
- Dynamic Kinetic Resolution of Biaryl Lactones via a Chiral Bifunctional Amine Thiourea-Catalyzed Highly Atropoenantioselective Transesterification被引量：157收藏
- 作者：Yu, Chenguang Huang, He Li, Xiangmin Zhang, Yueteng Wang, Wei
- 机构：Univ New Mexico;E China Univ Sci & Technol;E China Univ Sci & Technol
- 来源：JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 2016
- 关键词：Enantioselectivity - Transesterification - Esters
- Potent Dual BET/HDAC Inhibitors for Efficient Treatment of Pancreatic Cancer被引量：129收藏
- 作者：He, Shipeng Dong, Guoqiang Li, Yu Wu, Shanchao Wang, Wei Sheng, Chunquan
- 机构：Second Mil Med Univ;East China Univ Sci & Technol;Shanghai Univ;Univ Arizona;Univ Arizona
- 来源：ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 2020
- 关键词：anticancer antitumor agents drug discovery heterocyles inhibitors
- Visible-Light-Promoted Nickel- and Organic-Dye-Cocatalyzed Formylation Reaction of Aryl Halides and Triflates and Vinyl Bromides with Diethoxyacetic Acid as a Formyl Equivalent被引量：126收藏
- 作者：Huang, He Li, Xiangmin Yu, Chenguang Zhang, Yueteng Mariano, Patrick S. Wang, Wei
- 机构：Univ New Mexico;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 2017
- 关键词：flow chemistry formylation nickel catalysis photoredox catalysis synthetic methods
- Bifunctional Cinchona Alkaloid Thiourea Catalyzed Highly Efficient, Enantioselective Aza-Henry Reaction of Cyclic Trifluoromethyl Ketimines: Synthesis of Anti-HIV Drug DPC 083被引量：122收藏
- 作者：Xie, Hexin Zhang, Yinan Zhang, Shilei Chen, Xiaobei Wang, Wei
- 机构：Univ New Mexico;E China Univ Sci & Technol
- 来源：ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 2011
- 关键词：alkaloids asymmetric synthesis aza-Henry reaction drug synthesis organocatalysis
- Chemo- and Regioselective Organo-Photoredox Catalyzed Hydroformylation of Styrenes via a Radical Pathway被引量：119收藏
- 作者：Huang, He Yu, Chenguang Zhang, Yueteng Zhang, Yongqiang Mariano, Patrick S. Wang, Wei
- 机构：Univ New Mexico;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 2017
- 关键词：Carboxylation - Catalysis - Regioselectivity - Hydroformylation - Free radicals - Styrene
- Catalytic enantioselective henry reactions of isatins: Application in the concise synthesis of (S)-(-)-spirobrassinin被引量：98收藏
- 作者：Liu, Lu Zhang, Shilei Xue, Fei Lou, Guangshun Zhang, Haoyi Ma, Shichao Duan, Wenhu Wang, Wei
- 机构： School of Pharmacy; Shanghai Institute of Materia Medica; Department of Chemistry and Chemical Biology
- 来源：Chemistry - A European Journal 2011
- 关键词：Chromatography - Catalysis
- Practical synthesis of C1 deuterated aldehydes enabled by NHC catalysis被引量：94收藏
- 作者：Geng, Huihui Chen, Xiaobei Gui, Jingjing Zhang, Yueteng Shen, Zuyuan Qian, Pengfei Chen, Junwei Zhang, Shilei Wang, Wei
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Soochow Univ;Soochow Univ;Univ Arizona
- 来源：NATURE CATALYSIS 2019
- 关键词：Reaction intermediates - Cost effectiveness - Condensation reactions - Deuterium - Catalysis
- Direct Cα-heteroarylation of structurally diverse ethers via a mild N-hydroxysuccinimide mediated cross-dehydrogenative coupling reaction被引量：89收藏
- 作者：Liu, Shihui Liu, Aoxia Zhang, Yongqiang Wang, Wei
- 机构：East China Univ Sci & Technol;Univ New Mexico
- 来源：CHEMICAL SCIENCE 2017
- 关键词：Free radical reactions - Atoms
- Direct, facile aldehyde and ketone α-selenenylation reactions promoted by L-prolinamide and pyrrolidine sulfonamide organocatalysts被引量：89收藏
- 作者：Wang, Jian Li, Hao Mei, Yujiang Lou, Bihshow Xu, Dingguo Xie, Daiqian Guo, Hua Wang, Wei
- 机构：Univ New Mexico;Nanjing Univ;E China Univ Sci & Technol
- 来源：JOURNAL OF ORGANIC CHEMISTRY 2005
- 关键词：Aldehydes - Amines - Hydrogen bonds - Ketones
- Organocatalytic Enantioselective Direct Additions of Aldehydes to 4-Vinylpyridines and Electron-Deficient Vinylarenes and ThEIr Synthetic Applications被引量：87收藏
- 作者：Wang, Sinan Li, Xiangmin Liu, Hongwei Xu, Li Zhuang, Jinchen Li, Jian Li, Hao Wang, Wei
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol;Univ New Mexico
- 来源：JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 2015
- 关键词：Ethers - Synthesis (chemical) - Catalysis - Enantioselectivity - Chemical activation - Pyridine
- Organocatalytic Enantioselective Cross-Aldol Reactions of Aldehydes with Isatins: Formation of Two Contiguous Quaternary Centered 3-Substituted 3-Hydroxyindol-2-ones被引量：81收藏
- 作者：Xue, Fei Zhang, Shilei Liu, Lu Duan, Wenhu Wang, Wei
- 机构：E China Univ Sci & Technol;Univ New Mexico
- 来源：CHEMISTRY-AN ASIAN JOURNAL 2009
- 关键词：aldehydes aldol isatins organocatalysis
- An Organocatalytic Cascade Approach toward Polysubstituted Quinolines and Chiral 1,4-Dihydroquinolines-Unanticipated Effect of N-Protecting Groups被引量：80收藏
- 作者：Zhang, Xinshuai Song, Xixi Li, Hao Zhang, Shilei Chen, Xiaobei Yu, Xinhong Wang, Wei
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol;Univ New Mexico
- 来源：ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 2012
- 关键词：1 4-dihydroquinolines cascade reactions divergent synthesis organocatalysis quinolines
- Enzymatic Cleavage and Subsequent Facile Intramolecular Transcyclization for in Situ Fluorescence Detection of γ-Glutamyltranspetidase Activities被引量：78收藏
- 作者：Tong, Hongjuan Zheng, Yongjun Zhou, Li Li, Xiangmin Qian, Rui Wang, Rui Zhao, Jianhong Lou, Kaiyan Wang, Wei
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Univ New Mexico
- 来源：ANALYTICAL CHEMISTRY 2016
- 关键词：Cancer cells - Cells - Diseases - Diagnosis - Cytology - Fluorescence spectroscopy - Probes - Enzymes - Product design
- Photocatalytic C-H silylation of heteroarenes by using trialkylhydrosilanes被引量：76收藏
- 作者：Liu, Shihui Pan, Peng Fan, Huaqiang Li, Hao Wang, Wei Zhang, Yongqiang
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Univ Arizona
- 来源：CHEMICAL SCIENCE 2019
- 关键词：Chemical stability
- Chiral amine-catalyzed enantioselective cascade aza-ene-type cyclization reactions被引量：76收藏
- 作者：Zu, Liansuo Xie, Hexin Li, Hao Wang, Jian Yu, Xinhong Wang, Wei
- 机构：E China Univ Sci & Technol;Univ New Mexico
- 来源：CHEMISTRY-A EUROPEAN JOURNAL 2008
- 关键词：aldehydes cascade reactions enamides organocatalysis
- Analyte Regeneration Fluorescent Probes for Formaldehyde Enabled by Regiospecific Formaldehyde-Induced Intramolecularity被引量：72收藏
- 作者：Xu, Hang Xu, Huan Ma, Shengnan Chen, Xiani Huang, Lixian Chen, Junwei Gao, Feng Wang, Rui Lou, Kaiyan Wang, Wei
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Univ Arizona;Univ Arizona
- 来源：JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 2018
- 关键词：Fluorescence spectroscopy - Fluorescence - Probes - Molecules
- Interplay of Direct Stereocontrol and Dynamic Kinetic Resolution in a Bifunctional Amine Thiourea Catalyzed Highly Enantioselective Cascade Michael-Michael Reaction被引量：69收藏
- 作者：Yu, Chenguang Zhang, Yinan Song, Aiguo Ji, Yafei Wang, Wei
- 机构：Univ New Mexico;Beijing Univ Chem Technol;E China Univ Sci & Technol;Chinese Acad Sci
- 来源：CHEMISTRY-A EUROPEAN JOURNAL 2011
- 关键词：amine thioureas cascade catalysis dynamic kinetic resolution organocatalysis tetrahydrothiophenes
- A Strategy Enabling Enantioselective Direct Conjugate Addition of Inert Aryl Methane Nucleophiles to Enals with a Chiral Amine Catalyst under Mild Conditions被引量：67收藏
- 作者：Li, Tengfei Zhu, Jin Wu, Deyan Li, Xiangmin Wang, Sinan Li, Hao Li, Jian Wang, Wei
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol;Univ New Mexico
- 来源：CHEMISTRY-A EUROPEAN JOURNAL 2013
- 关键词：aryl methane enals iminium catalysis Michael addition organocatalysis
- An enantioselective formal synthesis of (+)-(R)-α-lipoic acid by an L-proline-catalyzed aldol reaction被引量：64收藏
- 作者：Zhang, Shilei Chen, Xiaobei Zhang, Jiangang Wang, Wei Duan, Wenhu
- 机构： Department of Medicinal Chemistry; Shanghai Institute of Materia Medica; Department of Chemistry and Chemical Biology
- 来源：Synthesis 2008
- 关键词：Catalyst activity - Enantioselectivity - Synthesis (chemical)
- Asymmetric synthesis of isoquinolinonaphthyridines catalyzed by a chiral Br?nsted acid被引量：63收藏
- 作者：Li, Jianjun Fu, Yiwei Qin, Cong Yu, Yang Li, Hao Wang, Wei
- 机构： State Key Laboratory of Bioengineering Reactor; Department of Chemistry and Chemical Biology
- 来源：Organic and Biomolecular Chemistry 2017
- 关键词：Cyclization
- Diastereo- and Enantioselective Organocatalytic Direct Conjugate Addition of γ-Butenolide to Chalcones被引量：56收藏
- 作者：Zhang, Yinan Yu, Chenguang Ji, Yafei Wang, Wei
- 机构：E China Univ Sci & Technol;Univ New Mexico;Chinese Acad Sci
- 来源：CHEMISTRY-AN ASIAN JOURNAL 2010
- 关键词：enones lactones Michael addition organocatalysis thioureas
- Enantioselective Conjugate Addition of N-Heterocycles to α,β-Unsaturated Ketones Catalyzed by Chiral Primary Amines被引量：55收藏
- 作者：Luo, Guangshun Zhang, Shilei Duan, Wenhu Wang, Wei
- 机构：E China Univ Sci & Technol;Chinese Acad Sci;Univ New Mexico
- 来源：SYNTHESIS-STUTTGART 2009
- 关键词：primary amines N-heterocycles enones conjugate addition catalysis
- Synthesis of Aldehydes by Organocatalytic Formylation Reactions of Boronic Acids with Glyoxylic Acid被引量：49收藏
- 作者：Huang, He Yu, Chenguang Li, Xiangmin Zhang, Yongqiang Zhang, Yueteng Chen, Xiaobei Mariano, Patrick S. Xie, Hexin Wang, Wei
- 机构：Univ New Mexico;East China Univ Sci Technol;East China Univ Sci Technol
- 来源：ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 2017
- 关键词：arenes boron formylation organocatalysis synthetic methods
- Construction of Chiral Bridged Tricyclic Benzopyrans: Enantioselective Catalytic Diels-Alder Reaction and a One-Pot Reduction/Acid-Catalyzed Stereoselective Cyclization被引量：48收藏
- 作者：Song, Aiguo Zhang, Xinshuai Song, Xixi Chen, Xiaobei Yu, Chenguang Huang, He Li, Hao Wang, Wei
- 机构：Univ New Mexico;E China Univ Sci & Technol;E China Univ Sci & Technol
- 来源：ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 2014
- 关键词：cyclization decarboxylation heterocycles organocatalysis synthetic methods
- Ligand-free Cu-catalyzed [3+2] cyclization for the synthesis of pyrrolo[1,2-a]quinolines with ambient air as a terminal oxidant被引量：47收藏
- 作者：Yu, Yang Liu, Yuan Liu, Aoxia Xie, Hexin Li, Hao Wang, Wei
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Univ New Mexico
- 来源：ORGANIC & BIOMOLECULAR CHEMISTRY 2016
- 关键词：Catalysis - Chelation - Ligands - Oxidants
- FeCl3 promoted highly regioselective [3 + 2] cycloaddition of dimethyl 2-vinyl and aryl cyclopropane-1,1-dicarboxylates with aryl isothiocyanates被引量：46收藏
- 作者：Wang, Huina Yang, Wei Liu, Hong Wang, Wei Li, Hao
- 机构： Shanghai Institute of Materia Medica; School of Pharmacy
- 来源：Organic and Biomolecular Chemistry 2012
- 关键词：Chlorine compounds - Regioselectivity
- Pd-Catalyzed Debenzylation and Deallylation of Ethers and Esters with Sodium Hydride被引量：43收藏
- 作者：Mao, Yujian Liu, Ye Hu, Yanwei Wang, Liang Zhang, Shilei Wang, Wei
- 机构：Soochow Univ;Soochow Univ;Qingdao Agr Univ;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：ACS CATALYSIS 2018
- 关键词：sodium hydride palladium reduction debenzylation deallylation
- Rational Design of an Ultrasensitive and Highly Selective Chemodosimeter by a Dual Quenching Mechanism for CystEIne Based on a Facile Michael-Transcyclization Cascade Reaction被引量：37收藏
- 作者：Li, Xiangmin Zheng, Yongjun Tong, Hongjuan Qian, Rui Zhou, Lin Liu, Guixia Tang, Yun Li, Hao Lou, Kaiyan Wang, Wei
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Univ New Mexico
- 来源：CHEMISTRY-A EUROPEAN JOURNAL 2016
- 关键词：cascade reactions chemodosimeter click chemistry cystEIne fluorescent probes
