沈永嘉 收藏
(1993-03-01至2019-03-01 任职于 化学与分子工程学院精细化工研究所)
沈永嘉，男，1953年10月生于上海，1989年获博士学位，1990-1992年在德国Max-Planck-Institut fuer Polymerforschung进行博士后研究，1995年被华东理工大学聘为教授，1998年被聘为博士生导师。2005年度国家精品课程《制剂工程》负责人。 学术团体兼职 教育部化学及化工学科教学指导委员会副主任、制药工程专业教学指导分委员会主任；中国染料工业协会第5届理事；《华东理工大学学报》编委，《中国染料》编委； 四川大学四川省制药工程与... 详细>>
- Higher Order π-Conjugated Polycyclic Hydrocarbons with Open-Shell Singlet Ground State: Nonazethrene versus Nonacene被引量：128收藏
- 作者：Huang, Rui Phan, Hoa Herng, Tun Seng Hu, Pan Zeng, Wangdong Dong, Shao-qiang Das, Soumyajit Shen, Yongjia Ding, Jun Casanova, David Wu, Jishan
- 机构：Natl Univ Singapore;East China Univ Sci & Technol;Natl Univ Singapore;Euskal Herriko Unibertsitatea;Euskal Herriko Unibertsitatea
- 来源：JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 2016
- 关键词：Nuclear magnetic resonance - Shellfish - Ground state - Molecular orbitals - Molluscs - Energy gap - Sodium compounds - Calculations - Shells (structures)
- 质疑
- A highly selective naked-eye and fluorescent probe for fluoride ion based on 1,8-naphalimide and benzothizazole被引量：74收藏
- 作者：Chen, Xiaoxing Leng, Taohua Wang, Chengyun Shen, Yongjia Zhu, Weihong
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Shanghai Inst Qual Inspect & Tech Res
- 来源：DYES AND PIGMENTS 2017
- 关键词：Fluoride ion Fluorescent probe 1, 8-Napthalimide Benzothizazole
- 质疑
- AND-Logic Based Fluorescent Probe for Selective Detection of Lysosomal Bisulfite in Living Cells被引量：74收藏
- 作者：Li, Ji-Zhen Sun, Yi-Hang Wang, Cheng-Yun Guo, Zhi-Qan Shen, Yong-Jia Zhu, Wei-Hong
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：ANALYTICAL CHEMISTRY 2019
- 关键词：Probes - Sulfur dioxide - Biomarkers - Alkalinity - Computer circuits - Biocompatibility - Cytology - Fluorescence
- 质疑
- A novel colorimetric and fluorescent sensor for cyanide anions detection based on triphenylamine and benzothiadiazole被引量：71收藏
- 作者：Zhang, Qisong Zhang, Jian Zuo, Hujin Wang, Chengyun Shen, Yongjia
- 机构：E China Univ Sci & Technol; E China Univ Sci & Technol
- 来源：TETRAHEDRON 2016
- 关键词：Triphenylamine Benzothiadiazole Colorimetric Fluorescent Cyanide-sensing
- 质疑
- A coumarin-based fluorescent and colorimetric chemosensor for rapid detection of fluoride ion被引量：66收藏
- 作者：Ma, Liulei Leng, Taohua Wang, Kai Wang, Chengyun Shen, Yongjia Zhu, Weihong
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Shanghai Inst Qual Inspect & Tech Res
- 来源：TETRAHEDRON 2017
- 关键词：Coumarin Thiosemicarbazone Fluorescent probe Fluoride anion
- 质疑
- 葛根中有效成分的微波辅助萃取研究被引量：58收藏
- 作者：王娟 沈平孃 沈永嘉
- 机构：华东理工大学化学与制药学院;国家中药制药工程技术研究中心;国家中药制药工程技术研究中心
- 来源：《中国医药工业杂志》 2002
- 关键词：葛根素 总黄酮 微波辅助萃取 均匀设计
- 摘要：采用均匀设计法对微波辅助萃取葛根中有效成分的提取工艺进行考察 ,用紫外分光光度法和 HPL C法分别测定葛根中总黄酮和葛根素的含量。结果表明在采用 95 %乙醇作为溶剂时 ,优选出的最佳工艺条件为 :微波功率2 5 5 ...
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- Novel 2,1,3-benzothiadiazole derivatives used as selective fluorescent and colorimetric sensors for fluoride ion被引量：56收藏
- 作者：Wu, Jiefei Lai, Guoqiao Li, Zhifang Lu, Yunxiang Leng, Taohua Shen, Yongjia Wang, Chengyun
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol;Hangzhou Normal Univ;E China Univ Sci & Technol;E China Univ Sci & Technol
- 来源：DYES AND PIGMENTS 2016
- 关键词：Fluoride Fluorescent sensor Deprotonation 2,1,3-Benzothiadiazole Carbazole Phenothiazine
- 质疑
- Conjugated poly(aryleneethynylenesiloles) and their application in detecting explosives被引量：56收藏
- 作者：Shu, Weifu Guan, Changwei Guo, Wenhao Wang, Chengyun Shen, Yongjia
- 机构：E China Univ Sci & Technol; E China Univ Sci & Technol
- 来源：JOURNAL OF MATERIALS CHEMISTRY 2012
- 关键词：Explosives detection - Chemical reactions - Quenching
- 质疑
- 蛋白质二级结构的红外光谱被引量：53收藏
- 作者：周瑞明 沈永嘉
- 机构：温州师范学院化学系;华东理工大学精细化工研究所
- 来源：《华东理工大学学报（自然科学版）》 1997
- 关键词：蛋白质 红外光谱 多肽链 氢键 二级结构
- 摘要：蛋白质的多肽链组成了各种特定的三维空间构象，氢键在维系这种构造中起着十分重要的作用。本文通过红外光谱法研究了蛋白质的二级结构和氢键在维系这种构造中的作用，发现具有螺旋和折叠构象的多肽链主要以反式构象为特征排布。
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- A novel colorimetric and fluorescent probe for the highly selective and sensitive detection of palladium based on Pd(0) mediated reaction被引量：51收藏
- 作者：Wang, Kai Lai, Guoqiao Li, Zhifang Liu, Mengmeng Shen, Yongjia Wang, Chengyun
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol;Hangzhou Normal Univ
- 来源：TETRAHEDRON 2015
- 关键词：Fluorescent probe Palladium species Naked eye detection Coumarin dye
- 质疑
- Dual quenching strategy for sensitive detection of toxic thiolphenols based on a NIR-illuminant platform with a large Stokes shift被引量：48收藏
- 作者：Wang, Kai Zhao, Cheng-Xi Leng, Tao-Hua Wang, Cheng-Yun Lu, Yun-Xiang Shen, Yong-Jia Zhu, Wei-Hong
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Shanghai Inst Qual Inspect & Tech Res
- 来源：DYES AND PIGMENTS 2018
- 关键词：Isophorone-based dye Near-infrared fluorescence Large Stokes shift Thiophenol DFT calculations Fluorescent imaging
- 质疑
- 微波辅助萃取葛根中有效成份的研究被引量：45收藏
- 作者：王娟 沈永嘉 王娟 沈平孃
- 机构：华东理工大学化学与制药学院;国家中药制药工程技术研究中心
- 来源：《中国药科大学学报》 2002
- 关键词：总黄酮 葛根素 微波辅助萃取 葛根 工艺条件
- 摘要：目的 以总黄酮和葛根素的含量为指标,研究微波辅助革取葛根的提取工艺。方法 采用连续微波辐射方式进行微波萃取参数的单一因素考察。结果 微波功率、辐射时间、溶剂用量、原料粉碎度、原料含水量等工艺参数的选择对葛根中有效成分的提...
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- A colorimetric and turn-on NIR fluorescent probe based on xanthene system for sensitive detection of thiophenol and its application in bioimaging被引量：45收藏
- 作者：Guo, Shao-Hua Leng, Tao-Hua Wang, Kai Wang, Cheng-Yun Shen, Yong-Jia Zhu, Wei-Hong
- 机构： Shanghai Key Laboratory of Functional Materials Chemistry; National Food Quality Supervision and Inspection Center / Shanghai Institute of Quality Inspection and Technical Research
- 来源：Talanta 2018
- 关键词：Fluorescence - Colorimetry - Infrared devices - Xanthenes - Probes - Lanthanum compounds
- 质疑
- An ultrasensitive fluorescent probe for hydrazine detection and its application in water samples and living cells被引量：44收藏
- 作者：Guo, Shao-Hua Guo, Zhi-Qian Wang, Cheng-Yun Shen, Yongjia Zhu, Wei-Hong
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：TETRAHEDRON 2019
- 关键词：Ultrasensitive Hydrazine Real water Bioimaging
- 质疑
- A novel colorimetric and fluorometric fluoride ion probe based on photoinduced electron transfer signaling mechanism被引量：43收藏
- 作者：Yuan, Xiao Xu, Xiaojia Zhao, Chengxi Zhang, Fei Lu, Yunxiang Shen, Yongjia Wang, Chengyun
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：SENSORS AND ACTUATORS B-CHEMICAL 2017
- 关键词：Fluorescent probe Fluoride ion Deprotonation Photoinduced electron transfer
- 质疑
- Characteristics of bicalutamide solid dispersions and improvement of the dissolution被引量：41收藏
- 作者：Ren, Fuzheng Jing, Qiufang Tang, Yanhui Shen, Yongjia Chen, Jialei Gao, Feng Cui, Jingbin
- 机构：E China Univ Sci & Technol
- 来源：DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY 2006
- 关键词：bicalutamide solid dispersion PVPK30 dissolution rate amorphous state
- 质疑
- Quantitative determination of puerarin in dog plasma by HPLC and study on the relative bioavailability of sustained release tablets被引量：38收藏
- 作者：Ren, Fuzheng Jing, Qiufang Shen, Yongjia Ma, Hongmei Cui, Jingbin
- 机构：E China Univ Sci & Technol
- 来源：JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS 2006
- 关键词：puerarin sustained release tablets Yufengningxin tablets bioavailability HPLC
- 质疑
- A novel naphthalimide-based probe for highly sensitive and selective recognition of ?uoride ion被引量：37收藏
- 作者：Yuan, Xiao Zhao, Cheng-Xi Lu, Yun-Xiang Shen, Yong-Jia Wang, Cheng-Yun
- 机构： Shanghai Key Laboratory of Functional Materials Chemistry; Department of Chemistry
- 来源：Journal of Photochemistry and Photobiology A: Chemistry 2018
- 关键词：Color - Colorimetry - Fluorescence - Fluorine compounds - Hydrogen bonds - Ions - Quenching
- 质疑
- A coumarin-based near-infrared fluorescent probe with a large stokes shift for the sequential recognition of Ni2+ and CN- : Performance research and quantum calculation被引量：37收藏
- 作者：Wang, Kai Zhao, Chengxi Guo, Shaohua Lu, Yunxiang Shen, Yongjia Wang, Chengyun
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY 2019
- 关键词：Near-infrared fluorescence Large stokes shift Sequential recognition Quantum calculation
- 质疑
- A calorimetric and turn-on NIR fluorescent probe based on xanthene system for sensitive detection of thiophenol and its application in bioimaging被引量：36收藏
- 作者：Guo, Shao-Hua Leng, Tao-Hua Wang, Kai Wang, Cheng-Yun Shen, Yong-Jia Zhu, Wei-Hong
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Shanghai Inst Qual Inspect & Tech Res
- 来源：TALANTA 2018
- 关键词：Near-Infrared (NIR) fluorescence Probe Thiophenol Bioimaging
- 质疑
- Highly soluble perylene tetracarboxylic diimides and tetrathiafulvalene-perylene tetracarboxylic diimide-tetrathiafulvalene triads被引量：35收藏
- 作者：Zhang, Yu Xu, Zheng Cai, Liangzhen Lai, Guoqiao Qiu, Haixiao Shen, Yongjia
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol;Hangzhou Normal Univ;E China Univ Sci & Technol
- 来源：JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY 2008
- 关键词：Donor Acceptor Tetrathiafulvalene Perylene tetracarboxylic diimide Photoinduced electron transfer
- 质疑
- 均匀设计优选微波辅助萃取何首乌中有效成分的研究被引量：34收藏
- 作者：王娟 沈平孃 沈永嘉
- 机构：华东理工大学化学与制药学院;国家中药制药工程技术研究中心
- 来源：《中草药》 2003
- 关键词：均匀设计 优选 微波辅助萃取 何首乌 有效成分 研究
- 摘要：目的 研究微波辅助萃取何首乌的提取工艺。方法 以总蒽醌和 2 ,3,5 ,4′-四羟基二苯乙烯 - 2 - O-β- D -葡萄糖苷 (二苯乙烯苷 )的含量为指标 ,通过均匀设计的方法 ,采用连续微波辐射方法进行微波萃取...
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- 白藜芦醇类似物的合成被引量：30收藏
- 作者：朱玉松 罗世能 沈永嘉 俞惠新 陈波 张来国
- 机构：华东理工大学精细化工研究所;江苏省原子医学研究所无锡214063;江苏省原子医学研究所;江南大学化学与材料工程学院无锡214036;江南大学化学与材料工程学院
- 来源：《有机化学》 2006
- 关键词：白藜芦醇类似物 3,4’ 5-三羟基-反式-二苯乙烯 生理活性
- 摘要：3,5-二甲氧基苄溴(4)与NaCN反应生成3,5-二甲氧基苄腈(5),5经水解得到3,5-二甲氧基苯乙酸(6).5与苯甲醛或取代苯甲醛发生Knoevenagel反应生成化合物2a～2d,为Z式构型.6与苯甲醛或取代苯甲...
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- A large Stokes shift, sequential, colorimetric fluorescent probe for sensing Cu2+/S2+ and its applications被引量：29收藏
- 作者：Li, Ji-Zhen Leng, Tao-Hua Wang, Zhi-Qiang Zhou, Li Gong, Xue-Qing Shen, Yong-Jia Wang, Cheng-Yun
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Shanghai Inst Qual Inspect & Tech Res;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY 2019
- 关键词：Copper ions Sulfide Large Stokes shift Colorimetric Near-infrared DFT calculations
- 质疑
- A novel coumarin-based fluorescence enhancement and colorimetric probe for Cu2+ via selective hydrolysis reaction被引量：28收藏
- 作者：Tan, Wenbin Leng, Taohua Lai, Guoqiao Li, Zhifang Wang, Kai Shen, Yongjia Wang, Chengyun
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol;Shanghai Inst Qual Inspect & Tech Res;Hangzhou Normal Univ
- 来源：JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY 2016
- 关键词：Coumarin derivatives Copper ion Fluorescence enhancement Hydrolysis reaction
- 质疑
- A Redox Stimulation-Activated Amphiphile for Enhanced Photodynamic Therapy被引量：28收藏
- 作者：Xue, Yudong Tian, Jia Liu, Zhiyong Chen, Jianbo Wu, Mengsi Shen, Yongjia Zhang, Weian
- 机构：East China Univ Sci & Technol
- 来源：BIOMACROMOLECULES 2019
- 关键词：Micelles - Tumors - Gas generators - Fluorescence - Photodynamic therapy - Oxygen - Toxicity - Polyethylene glycols
- 质疑
- Synthesis of zincic phthalocyanine derivative functionalized with four peripheral tetrathiafulvalene units被引量：27收藏
- 作者：Hu, YY Shen, YJ
- 机构：E China Univ Sci & Technol
- 来源：JOURNAL OF HETEROCYCLIC CHEMISTRY 2002
- 质疑
- 当归中阿魏酸的提取和纯化研究被引量：25收藏
- 作者：刘芝兰 王娟 沈平 沈永嘉
- 机构：华东理工大学精细化工研究所结构可控先进功能材料及其制备教育部重点实验室;国家中药制药工程研究中心
- 来源：《高校化学工程学报》 2007
- 关键词：微波辅助提取 阿魏酸 当归 均匀设计 高速逆流色谱
- 摘要：以当归中主要活性物质阿魏酸的含量为指标,采用单因素及均匀设计实验的方法,确定了微波辅助提取当归中阿魏酸的最优工艺条件:乙醇浓度90%,微波功率850W,液固比6:1(mL:g),辐射时间9min,粒径大小为2mm,浸泡时...
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- A novel fluorescent probe with a large stokes shift for cysteine based on dicyanoisophorone被引量：24收藏
- 作者：Hou, Jiaqi Cai, Pengfei Wang, Chengyun Shen, Yongjia
- 机构：East China Univ Sci & Technol; East China Univ Sci & Technol
- 来源：TETRAHEDRON LETTERS 2018
- 关键词：Fluorescent probe Dicyanoisophorone Large stokes shift Cysteine Cell imaging
- 质疑
