- Predicting physical stability of solid dispersions by machine learning techniques被引量：128收藏
- 作者：Han, Run Xiong, Hui Ye, Zhuyifan Yang, Yilong Huang, Tianhe Jing, Qiufang Lu, Jiahong Pan, Hao Ren, Fuzheng Ouyang, Defang
- 机构：Univ Macau;East China Univ Sci & Technol;Liaoning Univ
- 来源：JOURNAL OF CONTROLLED RELEASE 2019
- 关键词：Solid dispersion Physical stability Machine learning Molecular modeling
- 质疑
- Characteristics of bicalutamide solid dispersions and improvement of the dissolution被引量：41收藏
- 作者：Ren, Fuzheng Jing, Qiufang Tang, Yanhui Shen, Yongjia Chen, Jialei Gao, Feng Cui, Jingbin
- 机构：E China Univ Sci & Technol
- 来源：DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY 2006
- 关键词：bicalutamide solid dispersion PVPK30 dissolution rate amorphous state
- 质疑
- Quantitative determination of puerarin in dog plasma by HPLC and study on the relative bioavailability of sustained release tablets被引量：38收藏
- 作者：Ren, Fuzheng Jing, Qiufang Shen, Yongjia Ma, Hongmei Cui, Jingbin
- 机构：E China Univ Sci & Technol
- 来源：JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS 2006
- 关键词：puerarin sustained release tablets Yufengningxin tablets bioavailability HPLC
- 质疑
- HPLC determination of anethole trithione and its application to pharmacokinetics in rabbits被引量：20收藏
- 作者：Jing, Qiufang Shen, Yongjia Ren, Fuzheng Chen, Jianming Jiang, Zhiting Peng, Baoliang Leng, Yixin Dong, Jing
- 机构：E China Univ Sci & Technol;Second Mil Med Univ
- 来源：JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS 2006
- 关键词：anetbole trithione tablets self-microemulsifying drug delivery system bioavailability HPLC
- 质疑
- Stabilizing Effect of Soluplus on Erlotinib Metastable Crystal Form in Microparticles and Amorphous Solid Dispersions被引量：18收藏
- 作者：Jia, Shuyu Ning, Shangqi Leng, Yuting Jing, Qiufang Xu, Zhongyu Ren, Fuzheng
- 机构：East China Univ Sci & Technol
- 来源：POLYMERS 2022
- 关键词：erlotinib soluplus microparticles solid dispersions stabilization
- 质疑
- Investigating molecular interactions of high-loaded glipizide-HPMCAS microparticles by integrated experimental and modeling techniques被引量：17收藏
- 作者：Li, Qiang Zhao, Qianqian Jing, Qiufang Ma, Xiaosi Chen, Ning Ren, Guobin Ouyang, Defang Ren, Fuzheng
- 机构：East China Univ Sci & Technol;Univ Macau
- 来源：EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES 2019
- 关键词：Glipizide Hydroxypropyl methylcellulose acetate succinate (HPMCAS) Molecular interaction Molecular dynamics simulation
- 质疑
- Determination of nelfinavir mesylate as bulk drug and in pharmaceutical dosage form by stability indicating HPLC被引量：14收藏
- 作者：Jing, Qiufang Shen, Yongjia Tang, Yanhui Ren, Fuzheng Yu, Xinhong Hou, Zhian
- 机构：E China Univ Sci & Technol
- 来源：JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS 2006
- 关键词：nelfinavir mesylate reversed-phase HPLC pharmaceutical preparations validation isocratic elution
- 质疑
- Improving the physicochemical properties of bicalutamide by complex formation with bovine serum albumin被引量：12收藏
- 作者：Yang, Congbin Di, Peiwen Fu, JinPing Xiong, Hui Jing, Qiufang Ren, Guobin Tang, Yun Zheng, Wenyun Liu, Guixia Ren, Fuzheng
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES 2017
- 关键词：Bovine serum albumin Bicalutamide Anti-solvent precipitation Interaction Molecular docking
- 质疑
- Complexes of Felodipine Nanoparticles With Zein Prepared Using a Dual Shift Technique被引量：11收藏
- 作者：Ren, Fuzheng Fu, Jinping Xiong, Hui Cui, Lin Ren, Guobin Guan, Haiying Jing, Qiufang
- 机构：East China Univ Sci & Technol;Shanghai SPH New Asia Pharmaceut Co Ltd
- 来源：JOURNAL OF PHARMACEUTICAL SCIENCES 2018
- 关键词：felodipine zein dual shift technique complexes hydrophobic interaction
- 质疑
- Modified rivaroxaban microparticles for solid state properties improvement based on drug-protein/polymer supramolecular interactions被引量：11收藏
- 作者：Chen, Ning Di, Peiwen Ning, Shangqi Jiang, Wenjun Jing, Qiufang Ren, Guobin Liu, Yan Tang, Yun Xu, Zhongyu Liu, Guixia Ren, Fuzheng
- 机构：East China Univ Sci & Technol
- 来源：POWDER TECHNOLOGY 2019
- 关键词：Bottom-up Dissolution Molecular docking Rivaroxaban Supramolecular interactions
- 质疑
- A mixed solvent system for preparation of spherically agglomerated crystals of ascorbic acid被引量：11收藏
- 作者：Ren, Fuzheng Zhou, Yaru Liu, Yan Fu, Jinping Jing, Qiufang Ren, Guobin
- 机构：East China Univ Sci & Technol
- 来源：PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY 2017
- 关键词：Ascorbic acid binary mixed solvent micromeritic properties spherical crystallization
- 质疑
- Immuno-Enhancing Effect of Ginsenoside Rh2 Liposomes on Foot-and-Mouth Disease Vaccine被引量：10收藏
- 作者：Miao, Saiya Jing, Qiufang Wang, Xuanyu Zheng, Wenyun Liu, Hui Tang, Liusiqi Wang, Xinzhu Ren, Fuzheng
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Shanghai Baoshan Ctr Dis Control & Prevent;East China Univ Sci & Technol
- 来源：MOLECULAR PHARMACEUTICS 2023
- 关键词：ginsenoside Rh2 liposomes W/O/W emulsion foot-and-mouth disease vaccine immune adjuvant
- 质疑
- Corosolic acid-modified lipid nanoparticles as delivery carriers for DNA vaccines against avian influenza被引量：10收藏
- 作者：Guo, Ziyan Jing, Qiufang Xu, Zhongyu Zhang, Dahe Zheng, Wenyun Ren, Fuzheng
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Suzhou Womei Biol Co Ltd;East China Univ Sci & Technol
- 来源：INTERNATIONAL JOURNAL OF PHARMACEUTICS 2023
- 关键词：Lipid nanoparticles Cholesterol Corosolic acid Avian influenza vaccine Immune responses
- 质疑
- Exploring the effect of PVP on the spherical agglomeration process and micromeritic properties of ascorbic acid被引量：10收藏
- 作者：Huang, Saixu Liu, Yan Zhou, Yaru Li, Qiang Ren, Guobin Jing, Qiufang Ren, Fuzheng
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：POWDER TECHNOLOGY 2019
- 关键词：Fourier transform infrared spectroscopy - Spheres - Hydrogen bonds - Nuclear magnetic resonance spectroscopy - Differential scanning calorimetry
- 质疑
- 应用多媒体进行工业药剂学教学实践的体会被引量：9收藏
- 作者：任福正 卓超 景秋芳 唐燕辉 崔景斌 沈永嘉
- 机构：华东理工大学药学院;华东理工大学化学与分子工程学院
- 来源：《化工高等教育》 2006
- 关键词：工业药剂学 多媒体 体会
- 摘要：工业药剂学作为我校精品课程进行建设的课程之一,进行了多媒体教学改革的尝试。我们扩充了教学的内容,提高了教学效率,收到了良好的教学效果。本文介绍了一些体会、摸索的方法和部分建议。
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- Screen for Inhibitors of Crystal Growth to Identify Desirable Carriers for Amorphous Solid Dispersions Containing Felodipine被引量：7收藏
- 作者：Fu, Jinping Cui, Lin Yang, Congbin Xiong, Hui Ren, Guobin Ma, Xingyuan Jing, Qiufang Ren, Fuzheng
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：AAPS PHARMSCITECH 2018
- 关键词：felodipine zein inhibitory effect on crystal growth solid dispersions intermolecular interactions
- 质疑
- 制药工程专业卓越工程师培养计划的制订与实践被引量：6收藏
- 作者：任福正 罗晓燕 唐赟 景秋芳 王越 赵建宏 宋恭华
- 机构：华东理工大学药学院制药工程系
- 来源：《化工高等教育》 2015
- 关键词：制药工程专业 卓越工程师教育培养计划 培养方案 制订
- 摘要：根据国家卓越工程师教育培养计划和综合改革试点建设的目标,在对我校的制药工程专业培养计划进行梳理的基础上,我们重新制订了制药工程专业卓越工程师培养计划。近三年的实践表明,新的培养计划已逐渐适应现代制药行业的发展需求。本文对...
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- Self-Nanoemulsifying Drug Delivery System (SNEDDS) of Anethole Trithione by Combined Use of Surfactants被引量：6收藏
- 作者：Ren, Fuzheng Jing, Qiufang Cui, Jingbin Chen, Jianming Shen, Yongjia
- 机构：E China Univ Sci & Technol;Second Mil Med Univ;E China Univ Sci & Technol
- 来源：JOURNAL OF DISPERSION SCIENCE AND TECHNOLOGY 2009
- 关键词：Anethole trithione dissolution self-nanoemulsifying drug delivery system surfactant
- 质疑
- Synthesis and Characterization of D--Tocopheryl Polyethylene Glycol 1000 Succinate-Block-Poly (ε-caprolactone) Copolymer Used as Carriers for Microparticles被引量：6收藏
- 作者：Ren, Fuzheng Jing, Qiufang Cui, Jingbin Shen, Yongjia
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol
- 来源：JOURNAL OF DISPERSION SCIENCE AND TECHNOLOGY 2009
- 关键词：Copolymer D--tocopheryl polyethylene glycol 1000 succinate microparticle poly (epsilon-caprolactone)
- 质疑
- Characterization of ibuprofen microparticle and improvement of the dissolution被引量：5收藏
- 作者：Ren, Fuzheng Su, Jianping Xiong, Hui Tian, Ying Ren, Guobin Jing, Qiufang
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY 2017
- 关键词：Cremophor RH40 dissolution ibuprofen microparticle Tween 80
- 质疑
- Antisolvent Recrystallization Strategy to Screen Appropriate Carriers to Stabilize Filgotinib Amorphous Solid Dispersions被引量：5收藏
- 作者：Ren, Fuzheng Sun, Hanjing Cui, Lin Si, Yike Chen, Ning Ren, Guobin Jing, Qiufang
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：JOURNAL OF PHARMACEUTICAL SCIENCES 2018
- 关键词：filgotinib polymers screening method amorphous solid dispersions interaction
- 质疑
- 对工业药剂学教学改革的探讨被引量：4收藏
- 作者：高峰 陈彦佐 任福正 翁伟宇 景秋芳 崔景斌
- 机构：华东理工大学药学院药剂学教研室
- 来源：《化工高等教育》 2014
- 关键词：工业药剂学 教学改革 教学方法
- 摘要：工业药剂学是一门实践性很强的学科,在药学相关专业中占有十分重要的地位。如何培养适应社会发展的高素质医药人才是许多教学工作者始终重视的问题。本文对工业药剂学的教学改革进行了全面的探讨。
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- 药物制剂专业实验的教学探讨被引量：3收藏
- 作者：高峰 陈彦佐 任福正 翁伟宇 景秋芳 崔景斌
- 机构：华东理工大学药学院药物制剂教研室
- 来源：《实验室研究与探索》 2014
- 关键词：药物制剂 实验教学 教学模式
- 摘要：药物制剂专业实验是注重培养学生对于药物的剂型设计、工艺优化、质量控制和合理应用的一门应用性和实践性课程。药物制剂教研室针对传统药物制剂实验教学现状的不足之处,从改善教学模式、提高实验课科研含量并培养学生科研设计能力、加强...
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- New self-nanoemulsifying drug delivery system (SNEDDS) with amphiphilic diblock copolymer methoxy poly (ethylene glycol)-block-poly (ε-caprolactone)被引量：3收藏
- 作者：Ren, Fuzheng Gao, Yuan Chen, Jialei Jing, Qiufang Yu, Yan
- 机构：E China Univ Sci & Technol;Shanghai Univ Tradit Chinese Med
- 来源：PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY 2013
- 关键词：MPEG-b-PCL nanoemulsion Coenzyme Q(10) emulsification
- 质疑
- Kollicoat SR 30D游离膜的拉伸性能和透湿性被引量：3收藏
- 作者：陈爱玲 任福正 龙园园 田海玲 景秋芳
- 机构：华东理工大学药学院上海市新药设计重点实验室
- 来源：《中国医药工业杂志》 2013
- 关键词：KollicoatSR30D 增塑剂 致孔剂 延伸率 透湿性
- 摘要：采用平面铸膜法制备Kollicoat SR 30D游离膜,以自制简易膜拉伸试验装置初步检测膜的机械性能,并考察增塑剂及致孔剂对膜延伸率和膜透湿性的影响。结果表明,增大增塑剂枸橼酸三乙酯(TEC)的用量可使膜延伸率和透湿性...
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- 2,4-二硝基氟苯柱前衍生化法测定普瑞巴林被引量：3收藏
- 作者：巫婷 景秋芳 叶波 沈永嘉
- 机构：华东理工大学精细化工研究所结构可控先进功能材料及其制备教育部重点实验室;华东理工大学药学院;浙江三门腾龙化工有限公司
- 来源：《高校化学工程学报》 2010
- 关键词：普瑞巴林 2,4-二硝基氟苯 高效液相色谱 柱前衍生化
- 摘要：利用2,4-二硝基氟苯为柱前衍生剂,建立了用高效液相色谱法测定普瑞巴林的方法。考察了光、反应温度、摩尔比和反应时间对衍生化反应的影响,确定了最佳衍生反应条件:在65℃水浴中避光反应75min。色谱柱为C18,流动相为50...
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- The Physicochemical Investigation of 17β-Estradiol Crystalline Prepared by In Situ pH-Dependent Solubility Technique with Polyvinylpyrrolidone被引量：2收藏
- 作者：Xiong, Hui Fu, Jinping Sun, Hanjing Wang, Enfu Ding, Yunhui Ren, Guobin Jing, Qiufang Ren, Fuzheng
- 机构：East China Univ Sci & Technol;Shanghai Zhongxi Sunve Pharmaceut Co Ltd
- 来源：AAPS PHARMSCITECH 2017
- 关键词：17 beta-estradiol crystalline pH-dependent solubility polyvinylpyrrolidone
- 质疑
- 工业药剂学教学实践中质量源于设计理念的应用探索被引量：2收藏
- 作者：任福正 郑斯骥 景秋芳 罗晓燕 高峰
- 机构：华东理工大学药学院制药工程系
- 来源：《化工高等教育》 2015
- 关键词：质量源于设计 工业药剂学 教学实践 应用探索
- 摘要：质量源于设计理念现已被制药行业接受,并用于保证药品质量。工业药剂学作为制药工程的专业课程,为适应现代制药行业发展需要,授课过程中融入了质量源于设计理念,授课大纲和授课内容适时进行了调整。同时引入基于质量源于设计理念的案例...
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