成果/Result
- Notable mucosal immune responses induced in the intestine of zebrafish (Danio rerio) bath-vaccinated with a live attenuated Vibrio anguillarum vaccine被引量：60收藏
- 作者：Liu, Xiaohong Wu, Haizhen Chang, Xinyue Tang, Yufei Liu, Qin Zhang, Yuanxing
- 机构：E China Univ Sci & Technol
- 来源：FISH & SHELLFISH IMMUNOLOGY 2014
- 关键词：Live attenuated Vibrio anguillarum Zebrafish bath-vaccination Mucosal immune responses
- Critical role for a promoter discriminator in RpoS control of virulence in Edwardsiella piscicida被引量：51收藏
- 作者：Yin, Kaiyu Guan, Yunpeng Ma, Ruiqing Wei, Lifan Liu, Bing Liu, Xiaohong Zhou, Xiangshan Ma, Yue Zhang, Yuanxing Waldor, Matthew K. Wang, Qiyao
- 机构：East China Univ Sci & Technol;Qingdao Natl Lab Marine Sci & Technol;East China Univ Sci & Technol;Univ Autonoma Barcelona;Brigham & Womens Hosp
- 来源：PLOS PATHOGENS 2018
- Role of intestinal inflammation in predisposition of Edwardsiella tarda infection in zebrafish (Danio rerio)被引量：51收藏
- 作者：Liu, Xiaohong Chang, Xinyue Wu, Haizhen Xiao, Jingfan Gao, Yuan Zhang, Yuanxing
- 机构：E China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol
- 来源：FISH & SHELLFISH IMMUNOLOGY 2014
- 关键词：Edwardsiella tarda Intestinal inflammation Zebrafish Infection Antimicrobial response
- Efficacy of Montanide? ISA 763 A VG as aquatic adjuvant administrated with an inactivated Vibrio harveyi vaccine in turbot (Scophthalmus maximus L.)被引量：42收藏
- 作者：Xu, Wenting Jiao, Chenglong Bao, Pengcheng Liu, Qin Wang, Pengbo Zhang, Ruilin Liu, Xiaohong Zhang, Yuanxing
- 机构：East China Univ Sci & Technol;Shanghai Engn Res Ctr Maricultured Anim Vaccines;Shanghai Wei Sheng Marine Biotechnol Co Ltd;Fudan Univ
- 来源：FISH & SHELLFISH IMMUNOLOGY 2019
- 关键词：Vibrio harveyi Inactivated vaccine Adjuvant Efficient protection
- Flagellin enhances the immunoprotection of formalin-inactivated Edwardsiella tarda vaccine in turbot被引量：39收藏
- 作者：Liu, Xiaohong Zhang, Hua Jiao, Chenglong Liu, Qin Zhang, Yuanxing Xiao, Jingfan
- 机构：East China Univ Sci & Technol;Shanghai Engn Res Ctr Maricultured Anim Vaccines;Shanghai Collaborat Innovat Ctr Biomfg
- 来源：VACCINE 2017
- 关键词：Flagellin Vaccine Adjuvant Edwardsiella tarda Turbot
- Isolation of a Virulent Aeromonas salmonicida subsp. masoucida bacteriophage and Its Application in Phage Therapy in Turbot (Scophthalmus maximus)被引量：36收藏
- 作者：Xu, Zhenhe Jin, Peng Zhou, Xiangshan Zhang, Yuanxing Wang, Qiyao Liu, Xiaohong Shao, Shuai Liu, Qin
- 机构：East China Univ Sci & Technol;Southern Marine Sci & Engn Guangdong Lab Zhuhai;Shanghai Engn Res Ctr Maricultured Anim Vaccines
- 来源：APPLIED AND ENVIRONMENTAL MICROBIOLOGY 2021
- 关键词：Aeromonas salmonicida subsp. masoucida antibacterial aquaculture phage therapy turbot Scophthalmus maximus
- An oral vaccine based on chitosan/aluminum adjuvant induces both local and systemic immune responses in turbot (Scophthalmus maximus)被引量：34收藏
- 作者：Jin, Peng Sun, Fei Liu, Qin Wang, Qiyao Zhang, Yuanxing Liu, Xiaohong
- 机构：East China Univ Sci & Technol;Southern Marine Sci & Engn Guangdong Lab Zhuhai;Shanghai Engn Res Ctr Maricultured Anim Vaccines
- 来源：VACCINE 2021
- 关键词：Alum adjuvant Chitosan nanoparticles Oral vaccine Vibrio anguillarum
- Efficacy of chitosan oligosaccharide as aquatic adjuvant administrated with a formalin-inactivated Vibrio anguillarum vaccine被引量：34收藏
- 作者：Liu, Xiaohong Zhang, Hua Gao, Yuan Zhang, Yang Wu, Haizhen Zhang, Yuanxing
- 机构：E China Univ Sci & Technol;Shanghai Engn Res Ctr Maricultured Anim Vaccines;Shanghai Collaborat Innovat Ctr Biomfg Technol
- 来源：FISH & SHELLFISH IMMUNOLOGY 2015
- 关键词：Water-soluble adjuvant Chitosan oligosaccharide Formalin-inactivated vaccine Vibrio anguillarum
- Synergistic effect of a combined live Vibrio anguillarum and Edwardsiella piscicida vaccine in turbot被引量：32收藏
- 作者：Bao, Pengcheng Sun, Xiang Liu, Qin Zhang, Yuanxing Liu, Xiaohong
- 机构：East China Univ Sci & Technol;Shanghai Engn Res Ctr Maricultured Anim Vaccines
- 来源：FISH & SHELLFISH IMMUNOLOGY 2019
- 关键词：Combined-vaccination Vibrio anguillarum Edwardsiella piscicida Immune synergy
- A bacterial Pathogen Senses Host Mannose to Coordinate Virulence被引量：31收藏
- 作者：Wei, Lifan Qiao, Haoxian Sit, Brandon Yin, Kaiyu Yang, Guanhua Ma, Ruiqing Ma, Jiabao Yang, Chun Yao, Jun Ma, Yue Xiao, Jingfan Liu, Xiaohong Zhang, Yuanxing Waldor, Matthew K. Wang, Qiyao
- 机构：East China Univ Sci & Technol;Qingdao Natl Lab Marine Sci & Technol;Shanghai Engn Res Ctr Maricultured Anim Vaccines;Brigham & Womens Hosp;Harvard Med Sch
- 来源：ISCIENCE 2019
- Transposon insertion sequencing reveals T4SS as the major genetic trait for conjugation transfer of multi-drug resistance pEIB202 from Edwardsiella被引量：25收藏
- 作者：Liu, Yang Gao, Yanan Liu, Xiaohong Liu, Qin Zhang, Yuanxing Wang, Qiyao Xiao, Jingfan
- 机构：East China Univ Sci & Technol;Shanghai Engn Res Ctr Maricultured Anim Vaccines;Shanghai Collaborat Innovat Ctr Biomfg
- 来源：BMC MICROBIOLOGY 2017
- 关键词：Plasmid conjugation Edwardsiella Piscicida Tis T4SS RNA-seq EsrB
- balanced role of T3SS and T6SS in contribution to the full virulence of Edwardsiella piscicida被引量：24收藏
- 作者：Hu, Tianjian Chen, Ran Zhang, Lingzhi Wang, Zhuang Yang, Dahai Zhang, Yuanxing Liu, Xiaohong Liu, Qin
- 机构：East China Univ Sci & Technol;Shanghai Engn Res Ctr Maricultured Anim Vaccines;Shanghai Collaborat Innovat Ctr Biomfg
- 来源：FISH & SHELLFISH IMMUNOLOGY 2019
- 关键词：Edwardsiella piscicida Infection Live attenuated vaccine T3SS T6SS
- Stationary phase-dependent accumulation of ectoine is an efficient adaptation strategy in Vibrio anguillarum against cold stress被引量：24收藏
- 作者：Ma, Yue Wang, Qiyao Xu, Wensheng Liu, Xiaohong Gao, Xiating Zhang, Yuanxing
- 机构：East China Univ Sci & Technol;Shanghai Engn Res Ctr Maricultured Anim Vaccines;Shanghai Collaborat Innovat Ctr Biomfg;Beijing Univ Agr
- 来源：MICROBIOLOGICAL RESEARCH 2017
- 关键词：Vibrio anguillarum Compatible solutes Ectoine ectABC proVWX Cold adaptation
- A live attenuated Vibrio anguillarum vaccine induces efficient immunoprotection in Tiger puffer (Takifugu rubripes)被引量：24收藏
- 作者：Liu, Xiaohong Jiao, Chenglong Ma, Yue Wang, Qiyao Zhang, Yuanxing
- 机构：East China Univ Sci & Technol;Shanghai Engn Res Ctr Maricultured Anim Vaccines;Shanghai Collaborat Innovat Ctr Biomfg
- 来源：VACCINE 2018
- 关键词：Live attenuated Vibrio anguillarum Tiger puffer Vibriosis Efficient immunoprotection
- A CpG-riched plasmid as vaccine adjuvant reduce antigen dose of an inactivated Vibrio anguillarum vaccine in turbot (Scophthalmus maximus L.)被引量：22收藏
- 作者：Sun, Xiang Jin, Peng Liu, Qin Wang, Qiyao Zhang, Yuanxing Liu, Xiaohong
- 机构：East China Univ Sci & Technol;Southern Marine Sci & Engn Guangdong Lab Zhuhai;Shanghai Engn Res Ctr Maricultured Anim Vaccines
- 来源：FISH & SHELLFISH IMMUNOLOGY 2020
- 关键词：Adjuvant Inactivated vaccine pCpG Vibrio anguillarum
- Shelf-life prediction and storage stability of Aeromonas bacteriophage vB_AsM_ZHF被引量：19收藏
- 作者：Xu, Zhenhe Ding, Zihan Zhang, Yuanxing Liu, Xiaohong Wang, Qiyao Shao, Shuai Liu, Qin
- 机构：East China Univ Sci & Technol;Southern Marine Sci & Engn Guangdong Lab Zhuhai;Shanghai Engn Res Ctr Maricultured Anim Vaccines
- 来源：VIRUS RESEARCH 2023
- 关键词：Lyophilization Phage therapy Prediction model Shelf-life Storage
- The Edwardsiella piscicida thioredoxin-like protein inhibits ASK1-MAPKs signaling cascades to promote pathogenesis during infection被引量：19收藏
- 作者：Yang, Dahai Liu, Xiaohong Xu, Wenting Gu, Zhaoyan Yang, Cuiting Zhang, Lingzhi Tan, Jinchao Zheng, Xin Wang, Zhuang Quan, Shu Zhang, Yuanxing Liu, Qin
- 机构：East China Univ Sci & Technol;Shanghai Engn Res Ctr Maricultured Anim Vaccines;Qingdao Natl Lab Marine Sci & Technol
- 来源：PLOS PATHOGENS 2019
- Design and evaluation of an Edwardsiella tarda DNA vaccine co-encoding antigenic and adjuvant peptide被引量：19收藏
- 作者：Liu, Xiaohong Xu, Jinmei Zhang, Hua Liu, Qin Xiao, Jingfan Zhang, Yuanxing
- 机构：East China Univ Sci & Technol;Shanghai Engn Res Ctr Maricultured Anim Vaccines
- 来源：FISH & SHELLFISH IMMUNOLOGY 2016
- 关键词：Edwardsiella tarda DNA vaccine Co-encoding Bicistronic expression system
- MviN mediates the regulation of environmental osmotic pressure on esrB to control the virulence in the marine fish pathogen Edwardsiella piscicida被引量：19收藏
- 作者：Yin, Kaiyu Zhang, Jin Ma, Jiabao Jin, Peng Ma, Yue Zhang, Yuanxing Liu, Xiaohong Wang, Qiyao
- 机构：East China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol;Shanghai Engn Res Ctr Maricultured Anim Vaccines
- 来源：MICROBIOLOGICAL RESEARCH 2020
- 关键词：Edwardsiella piscicida EsrB Lipid II flippase Osmotic pressure In vivo colonization
- Skin-injured Zebrafish, Danio rerio, are more Susceptible to Vibrio anguillarum Infection被引量：19收藏
- 作者：Liu, Xiaohong Wu, Haizhen Liu, Qin Wang, Qiyao Xiao, Jingfan Zhang, Yuanxing
- 机构：E China Univ Sci & Technol
- 来源：JOURNAL OF THE WORLD AQUACULTURE SOCIETY 2015
- YebC controls virulence by activating T3SS gene expression in the pathogen Edwardsiella piscicida被引量：18收藏
- 作者：Wei, Lifan Wu, Yanyan Qiao, Haoxian Xu, Wensheng Zhang, Yuanxing Liu, Xiaohong Wang, Qiyao
- 机构：East China Univ Sci & Technol;Beijing Agr Univ;Shanghai Collaborat Innovat Ctr Biomfg T;Shanghai Engn Res Ctr Maricultured Anim Vaccines
- 来源：FEMS MICROBIOLOGY LETTERS 2018
- 关键词：Edwardsiella piscicida YebC T3SS QS Tn-seq
- Edwardsiella piscicida Enters Nonphagocytic Cells via a Macropinocytosis-Involved Hybrid Mechanism被引量：17收藏
- 作者：Hu, Tianjian Zhang, Lingzhi Wang, Wei Yang, Dahai Xiao, Jingfan Zhang, Yuanxing Liu, Xiaohong Liu, Qin
- 机构：East China Univ Sci & Technol;Shanghai Engn Res Ctr Maricultured Anim Vaccines;Shanghai Collaborat Innovat Ctr Biomfg Technol;Univ Michigan;Univ Michigan
- 来源：JOURNAL OF BACTERIOLOGY 2019
- 关键词：Edwardsiella piscicida endocytosis internalization macropinocytosis nonphagocytic cells
- Profiling immune response in zebrafish intestine, skin, spleen and kidney bath-vaccinated with a live attenuated Vibrio anguillarum vaccine被引量：16收藏
- 作者：Liu, Xiaohong Wu, Haizhen Liu, Qin Wang, Qiyao Xiao, Jingfan Chang, Xinyue Zhang, Yuanxing
- 机构：E China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol
- 来源：FISH & SHELLFISH IMMUNOLOGY 2015
- 关键词：Live attenuated vaccine Zebrafish Immune response
- Polyactin A and CpG enhance inactivated Pseudomonas plecoglossicida vaccine potency in large yellow croaker (Larimichthys crocea)被引量：16收藏
- 作者：Wang, Wenwen Wang, Wei Xu, Wenjun Liu, Qin Zhang, Yuanxing Liu, Xiaohong
- 机构：East China Univ Sci & Technol;Zhejiang Marine Aquat Res Inst;Shanghai Engn Res Ctr Maricultured Anim Vaccines
- 来源：FISH & SHELLFISH IMMUNOLOGY 2022
- 关键词：Inactivated vaccine pCpG Polyactin A Pseudomonas plecoglossicida Larimichthys crocea
- Therapeutic efficacies of two newly isolated Edwardsiella phages against Edwardsiella piscicida infection被引量：16收藏
- 作者：Xu, Zhenhe Shao, Shuai Ding, Zihan Zhang, Yuanxing Wang, Qiyao Liu, Xiaohong Liu, Qin
- 机构：East China Univ Sci & Technol;Southern Marine Sci & Engn Guangdong Lab Zhuhai;Shanghai Engn Res Ctr Maricultured Anim Vaccines
- 来源：MICROBIOLOGICAL RESEARCH 2022
- 关键词：Aquaculture Cocktail Edwardsiella piscicida Phage therapy Turbot Zebrafish
- A compound ginseng stem leaf saponins and aluminium adjuvant enhances the potency of inactivated Aeromonas salmonicida vaccine in turbot被引量：13收藏
- 作者：Sun, Fei Zhou, Jie Zhang, Yuanxing Liu, Qin Wang, Qiyao Liu, Xiaohong
- 机构：East China Univ Sci & Technol;Southern Marine Sci & Engn Guangdong Lab Zhuhai;Shanghai Collaborat Innovat Ctr Biomfg;Shanghai Engn Res Ctr Maricultured Anim Vaccines
- 来源：FISH & SHELLFISH IMMUNOLOGY 2022
- 关键词：Adjuvant Inactivated vaccine Turbot GSLS Aeromonas salmonicida
- Genome-Wide Identification of Fitness Factors in Seawater for Edwardsiella piscicida被引量：13收藏
- 作者：Wei, Lifan Wu, Yanyan Yang, Guanhua Xu, Rongjing Liu, Xiaohong Liu, Qin Zhang, Yuanxing Ma, Yue Wang, Qiyao
- 机构：East China Univ Sci & Technol;Shanghai Engn Res Ctr Maricultured Anim Vaccines;Shanghai Collaborat Innovat Ctr Biomfg;Yantai Tianyuan Aquat Co Ltd
- 来源：APPLIED AND ENVIRONMENTAL MICROBIOLOGY 2019
- 关键词：Edwardsiella piscicida T3SS transposon insertion sequencing TIS oxidative phosphorylation seawater temperature
- Edwardsiella piscicida Interferes with Classical Endocytic Trafficking and Replicates in a Specialized Replication-Permissive Niche in Nonphagocytic Cells被引量：12收藏
- 作者：Zhang, Lingzhi Jiang, Jiatiao Zhang, Jin Liu, Xiaohong Yang, Dahai Zhang, Yuanxing Liu, Qin
- 机构：East China Univ Sci & Technol;Shanghai Engn Res Ctr Maricultured Anim Vaccines;Shanghai Collaborat Innovat Ctr Biomfg Technol
- 来源：JOURNAL OF BACTERIOLOGY 2021
- 关键词：Edwardsiella piscicida T3SS effector intracellular trafficking
- Pattern analysis of conditional essentiality (PACE)-based heuristic identification of an in vivo colonization determinant as a novel target for the construction of a live attenuated vaccine against Edwardsiella piscicida被引量：12收藏
- 作者：Ma, Ruiqing Yang, Guanhua Xu, Rongjing Liu, Xiaohong Zhang, Yuanxing Ma, Yue Wang, Qiyao
- 机构：East China Univ Sci & Technol;Qingdao Natl Lab Marine Sci & Technol;Shanghai Engn Res Ctr Maricultured Anim Vaccines;Yantai Tianyuan Aquat Co Ltd
- 来源：FISH & SHELLFISH IMMUNOLOGY 2019
- 关键词：Edwardsiella piscicida In vivo colonization Live attenuated vaccine PACE
- EsrB negatively regulates expression of the glutamine sythetase GlnA in the fish pathogen Edwardsiella piscicida被引量：10收藏
- 作者：Guan, Yunpeng Yin, Kaiyu Zhou, Mian Yang, Minjun Zhang, Yuanxing Liu, Xiaohong Wang, Qiyao
- 机构：East China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol;Shanghai Engn Res Ctr Maricultured Anim Vaccines;Chinese Natl Human Genome Ctr Shanghai
- 来源：FEMS MICROBIOLOGY LETTERS 2018
- 关键词：comparative proteomics EsrB Edwardsiella piscicida glnA
