成果/Result
- A Highly Sensitive and Selective OFF-ON Fluorescent Sensor for Cadmium in Aqueous Solution and Living Cell被引量：331收藏
- 作者：Cheng, Tanyu Xu, Yuifang Zhang, Shenyi Zhu, Weiping Qian, Xuhong Duan, Liping
- 机构：E China Univ Sci & Technol
- 来源：JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 2008
- FRET-Based Mito-Specific Fluorescent Probe for Ratiometric Detection and Imaging of Endogenous Peroxynitrite: Dyad of Cy3 and Cy5被引量：316收藏
- 作者：Jia, Xiaotong Chen, Qiangqiang Yang, Yingfang Tang, Yao Wang, Rui Xu, Yufang Zhu, Weiping Qian, Xuhong
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 2016
- 关键词：Fluorescence spectroscopy - Probes
- A Rhodamine-Based Hg2+ Sensor with High Selectivity and Sensitivity in Aqueous Solution: A NS2-Containing Receptor被引量：292收藏
- 作者：Huang, Junhai Xu, Yufang Qian, Xuhong
- 机构：E China Univ Sci & Technol
- 来源：JOURNAL OF ORGANIC CHEMISTRY 2009
- A highly selective fluorescent probe for fast detection of hydrogen sulfide in aqueous solution and living cells被引量：235收藏
- 作者：Xu, Zheng Xu, Lin Zhou, Ji Xu, Yufang Zhu, Weiping Qian, Xuhong
- 机构：E China Univ Sci & Technol
- 来源：CHEMICAL COMMUNICATIONS 2012
- A New Prodrug-Derived Ratiometric Fluorescent Probe for Hypoxia: High Selectivity of Nitroreductase and Imaging in Tumor Cell被引量：204收藏
- 作者：Cui, Lei Zhong, Ye Zhu, Weiping Xu, Yufang Du, Qingshan Wang, Xin Qian, Xuhong Xiao, Yi
- 机构：E China Univ Sci & Technol;Dalian Univ Technol DLUT
- 来源：ORGANIC LETTERS 2011
- Unique Tr-Output Optical Probe for Specific and Ultrasensitive Detection of Hydrazine被引量：161收藏
- 作者：Cui, Lei Ji, Chunfei Peng, Zhixing Zhong, Lin Zhou, Chaohui Yan, Luliang Qu, Song Zhang, Shuping Huang, Chusen Qian, Xuhong Xu, Yufang
- 机构：Shanghai Univ Sci & Technol;E China Univ Sci & Technol;Shanghai Normal Univ
- 来源：ANALYTICAL CHEMISTRY 2014
- Highly sensitive and selective Pd2+ sensor of naphthalimide derivative based on complexation with alkynes and thio-heterocycle被引量：155收藏
- 作者：Duan, Liping Xu, Yufang Qian, Xuhong
- 机构：E China Univ Sci & Technol; E China Univ Sci & Technol
- 来源：CHEMICAL COMMUNICATIONS 2008
- A New Class of Naphthalimide-Based Antitumor Agents That Inhibit Topoisomerase II and Induce Lysosomal Membrane Permeabilization and Apoptosis被引量：153收藏
- 作者：Chen, Zhuo Liang, Xin Zhang, Huanying Xie, Hua Liu, Jianwen Xu, Yufang Zhu, Weiping Wang, Yi Wang, Xin Tan, Shaoying Kuang, Dong Qian, Xuhong
- 机构：E China Univ Sci & Technol;Chinese Acad Sci
- 来源：JOURNAL OF MEDICINAL CHEMISTRY 2010
- Highly Selective and Sensitive Near-Infrared Fluorescent Sensors for Cadmium in Aqueous Solution被引量：127收藏
- 作者：Yang, Yangyang Cheng, Tanyu Zhu, Weiping Xu, Yufang Qian, Xuhong
- 机构：E China Univ Sci & Technol
- 来源：ORGANIC LETTERS 2011
- A highly sensitive long-wavelength fluorescence probe for nitroreductase and hypoxia: selective detection and quantification被引量：120收藏
- 作者：Guo, Ting Cui, Lei Shen, Jiaoning Zhu, Weiping Xu, Yufang Qian, Xuhong
- 机构：E China Univ Sci & Technol
- 来源：CHEMICAL COMMUNICATIONS 2013
- Selective and Ratiometric Fluorescent Trapping and Quantification of Protein Vicinal Dithiols and in Situ Dynamic Tracing in Living Cells被引量：119收藏
- 作者：Huang, Chusen Jia, Ti Tang, Mengfang Yin, Qin Zhu, Weiping Zhang, Chao Yang, Yi Jia, Nengqin Xu, Yufang Qian, Xuhong
- 机构：E China Univ Sci & Technol;Shanghai Normal Univ;Shanghai Normal Univ
- 来源：JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 2014
- 关键词：Sulfur compounds - Cell membranes - Fluorescence imaging - Biosynthesis - Probes - Cytology
- Red-Emission Fluorescent Probe Sensing Cadmium and Pyrophosphate Selectively in Aqueous Solution被引量：112收藏
- 作者：Cheng, Tanyu Wang, Tao Zhu, Weiping Chen, Xinlei Yang, Youjun Xu, Yufang Qin, Xuhong
- 机构：E China Univ Sci & Technol
- 来源：ORGANIC LETTERS 2011
- Engineering naphthalimide-cyanine integrated near-infrared dye into ROS-responsive nanohybrids for tumor PDT/PTT/chemotherapy被引量：109收藏
- 作者：Jin, Tongxia Cheng, Di Jiang, Guanyu Xing, Wenqian Liu, Peiwen Wang, Bin Zhu, Weiping Sun, Haitao Sun, Zhenrong Xu, Yufang Qian, Xuhong
- 机构：East China Univ Sci & Technol;East China Normal Univ;East China Univ Sci & Technol
- 来源：BIOACTIVE MATERIALS 2022
- 关键词：Near-infrared dye Integration strategy Phototherapy Combination therapy Drug delivery system
- A dual-emission and large Stokes shift fluorescence probe for real-time discrimination of ROS/RNS and imaging in live cells被引量：106收藏
- 作者：Guo, Ting Cui, Lei Shen, Jiaoning Wang, Rui Zhu, Weiping Xu, Yufang Qian, Xuhong
- 机构：E China Univ Sci & Technol
- 来源：CHEMICAL COMMUNICATIONS 2013
- A dual pH and temperature responsive polymeric fluorescent sensor and its imaging application in living cells被引量：102收藏
- 作者：Yin, Liyan He, Chunsheng Huang, Chusen Zhu, Weiping Wang, Xin Xu, Yufang Qian, Xuhong
- 机构：E China Univ Sci & Technol
- 来源：CHEMICAL COMMUNICATIONS 2012
- Versatile trifunctional chemosensor of rhodamine derivative for Zn2+, Cu2+ and His/Cys in aqueous solution and living cells被引量：90收藏
- 作者：Xu, Lin Xu, Yufang Zhu, Weiping Zeng, Bubing Yang, Chunmei Wu, Bin Qian, Xuhong
- 机构：E China Univ Sci & Technol
- 来源：ORGANIC & BIOMOLECULAR CHEMISTRY 2011
- A highly selective and sensitive fluorescence "turn-on" probe for Ag+ in aqueous solution and live cells被引量：87+ in aqueous solution and live cells')">收藏
- 作者：Xu, Lin Xu, Yufang Zhu, Weiping Yang, Chunmei Han, Le Qian, Xuhong
- 机构：E China Univ Sci & Technol
- 来源：DALTON TRANSACTIONS 2012
- Sulfur-substituted naphthalimides as photoactivatable anticancer agents: DNA interaction, fluorescence imaging, and phototoxic effects in cultured tumor cells被引量：76收藏
- 作者：Ott, Ingo Xu, Yufang Liu, Jianwen Kokoschka, Malte Harlos, Melanie Sheldrick, William S. Qian, Xuhong
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol;Free Univ Berlin;Ruhr Univ Bochum
- 来源：BIOORGANIC & MEDICINAL CHEMISTRY 2008
- 关键词：antitumor drugs naphthalimides phototoxicity photodynamic therapy photoinduced electron transfer (PET)
- Rhodamine-based fluorescent off-on sensor for Fe3+ - in aqueous solution and in living cells: 8-aminoquinoline receptor and 2: 1 binding被引量：74收藏
- 作者：Huang, Junhai Xu, Yufang Qian, Xuhong
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol;Shanghai Inst Pharmaceut Ind
- 来源：DALTON TRANSACTIONS 2014
- 关键词：Chromophores - Metals - Bioimaging - Fluorescence - Metal ions - Solutions - Nuclear magnetic resonance spectroscopy
- Highly Selective Fluorescent Probe for Vicinal-Dithiol-Containing Proteins and In Situ Imaging in Living Cells被引量：73收藏
- 作者：Huang, Chusen Yin, Qin Zhu, Weiping Yang, Yi Wang, Xin Qian, Xuhong Xu, Yufang
- 机构：E China Univ Sci & Technol
- 来源：ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 2011
- 关键词：fluorescent probes in situ imaging protein labeling redox proteomics vicinal dithiols
- SHAFTS: A Hybrid Approach for 3D Molecular Similarity Calculation. 2. Prospective Case Study in the Discovery of Diverse p90 Ribosomal S6 Protein Kinase 2 Inhibitors To Suppress Cell Migration被引量：71收藏
- 作者：Lu, Weiqiang Liu, Xiaofeng Cao, Xianwen Xue, Mengzhu Liu, Kangdong Zhao, Zhenjiang Shen, Xu Jiang, Hualiang Xu, Yufang Huang, Jin Li, Honglin
- 机构：Zhengzhou Univ;E China Univ Sci & Technol
- 来源：JOURNAL OF MEDICINAL CHEMISTRY 2011
- A small molecular fluorescent sensor functionalized silica microsphere for detection and removal of mercury, cadmium, and lead ions in aqueous solutions被引量：70收藏
- 作者：Ding, Yu Zhu, Weiping Xu, Yufang Qian, Xuhong
- 机构：E China Univ Sci & Technol
- 来源：SENSORS AND ACTUATORS B-CHEMICAL 2015
- 关键词：Fluorescent sensor Heavy metal ions Detection Removal Reusable
- Dual-responsive nanohybrid based on degradable silica-coated gold nanorods for triple-combination therapy for breast cancer被引量：68收藏
- 作者：Cheng, Di Ji, Yuejia Wang, Bin Wang, Yuyu Tang, Yao Fu, Yun Xu, Yufang Qian, Xuhong Zhu, Weiping
- 机构：East China Univ Sci & Technol
- 来源：ACTA BIOMATERIALIA 2021
- 关键词：Degradable organosilica Gold nanorod Multi-modal therapy Tumor ablation
- Fragment-Based Drug Design and Drug Repositioning Using Multiple Ligand Simultaneous Docking (MLSD): Identifying Celecoxib and Template Compounds as Novel Inhibitors of Signal Transducer and Activator of Transcription 3 (STAT3)被引量：68收藏
- 作者：Li, Huameng Liu, Aiguo Zhao, Zhenjiang Xu, Yufang Lin, Jiayuh Jou, David Li, Chenglong
- 机构：Ohio State Univ;Ohio State Univ;Nationwide Childrens Hosp;Huazhong Univ Sci & Technol;E China Univ Sci & Technol
- 来源：JOURNAL OF MEDICINAL CHEMISTRY 2011
- A novel ratiometric sensor for the fast detection of palladium species with large red-shift and high resolution both in aqueous solution and solid state被引量：65收藏
- 作者：Cui, Lei Zhu, Weiping Xu, Yufang Qian, Xuhong
- 机构：E China Univ Sci & Technol;Shanghai Univ Sci & Technol
- 来源：ANALYTICA CHIMICA ACTA 2013
- 关键词：Fluorescent probe Palladium Excited-state intramolecular proton transfer Paper strip Solid state fluorescence
- A highly selective and sensitive near-infrared fluorescence probe for arylamine N-acetyltransferase 2 in vitro and in vivo被引量：65收藏
- 作者：Wang, Xin Cui, Lei Zhou, Nannan Zhu, Weiping Wang, Rui Qian, Xuhong Xu, Yufang
- 机构：E China Univ Sci & Technol
- 来源：CHEMICAL SCIENCE 2013
- Discovery of Pteridin-7(8H)-one-Based Irreversible Inhibitors Targeting the Epidermal Growth Factor Receptor (EGFR) Kinase T790M/L858R Mutant被引量：63收藏
- 作者：Zhou, Wei Liu, Xiaofeng Tu, Zhengchao Zhang, Lianwen Ku, Xin Bai, Fang Zhao, Zhenjiang Xu, Yufang Ding, Ke Li, Honglin
- 机构：E China Univ Sci & Technol;Chinese Acad Sci;Chinese Acad Sci;Tech Univ Munich;Dalian Univ Technol
- 来源：JOURNAL OF MEDICINAL CHEMISTRY 2013
- Discovery of Potent and Noncovalent Reversible EGFR Kinase Inhibitors of EGFRL858R/T790M/C797S被引量：59收藏
- 作者：Li, Qiannan Zhang, Tao Li, Shiliang Tong, Linjiang Li, Junyu Su, Zhicheng Feng, Fang Sun, Deheng Tong, Yi Wang, Xia Zhao, Zhenjiang Zhu, Lili Ding, Jian Li, Honglin Xie, Hua Xu, Yufang
- 机构：East China Univ Sci & Technol;Chinese Acad Sci
- 来源：ACS MEDICINAL CHEMISTRY LETTERS 2019
- 关键词：EGFR mutant inhibitor C797S
- A dual channel chemodosimeter for Hg2+ and Ag+ using a 1,3-dithiane modified BODIPY被引量：57收藏
- 作者：Zhang, Xiaojun Xu, Yufang Guo, Peng Qian, Xuhong
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol
- 来源：NEW JOURNAL OF CHEMISTRY 2012
- 7b, a novel naphthalimide derivative, exhibited anti-inflammatory effects via targeted-inhibiting TAK1 following down-regulation of ERK1/2-and p38 MAPK-mediated activation of NF-κB in LPS-stimulated RAW264.7 macrophages被引量：57收藏
- 作者：Shao, Jin Li, Yiquan Wang, Ziyuan Xiao, Mengmeng Yin, Peihao Lu, Yanhua Qian, Xuhong Xu, Yufang Liu, Jianwen
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol;Shanghai Univ Tradit Chinese Med
- 来源：INTERNATIONAL IMMUNOPHARMACOLOGY 2013
- 关键词：7b Anti-inflammatory TAK1 MAPK NF-kappa B
