成果/Result
- LuxO controls extracellular protease, haemolytic activities and siderophore production in fish pathogen Vibrio alginolyticus被引量：66收藏
- 作者：Wang, Q. Liu, Q. Ma, Y. Rui, H. Zhang, Y.
- 机构：E China Univ Sci & Technol
- 来源：JOURNAL OF APPLIED MICROBIOLOGY 2007
- 关键词：haemolytic activity LuxO protease quorum sensing rpoN siderophore Vibrio alginolyticus
- Roles of LuxR in regulating extracellular alkaline serine protease A, extracellular polysaccharide and mobility of Vibrio alginolyticus被引量：63收藏
- 作者：Rui, Haopeng Liu, Qin Ma, Yue Wang, Qiyao Zhang, Yuanxing
- 机构：E China Univ Sci & Technol
- 来源：FEMS MICROBIOLOGY LETTERS 2008
- 关键词：Vibrio alginolyticus quorum sensing LuxR(val) ProA collagenase extracellular protease
- Role of Alkaline Serine Protease, Asp, in Vibrio alginolyticus Virulence and Regulation of Its Expression by LuxO-LuxR Regulatory System被引量：60收藏
- 作者：Rui Haopeng Liu, Qin Wang, Qiyao Ma, Yue Liu, Huan Shi, Cunbin Zhang, Yuanxing
- 机构：E China Univ Sci & Technol;Chinese Acad Fishery Sci
- 来源：JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY 2009
- 关键词：Alkaline serine protease asp quorum sensing Vibrio alginolyticus
- Regulation of Vibrio alginolyticus virulence by the LuxS quorum-sensing system被引量：59收藏
- 作者：Ye, J. Ma, Y. Liu, Q. Zhao, D. L. Wang, Q. Y. Zhang, Y. X.
- 机构：E China Univ Sci & Technol
- 来源：JOURNAL OF FISH DISEASES 2008
- 关键词：autoinducer AI-2 luxS quorum sensing Vibrio alginolyticus virulence
- Critical role for a promoter discriminator in RpoS control of virulence in Edwardsiella piscicida被引量：51收藏
- 作者：Yin, Kaiyu Guan, Yunpeng Ma, Ruiqing Wei, Lifan Liu, Bing Liu, Xiaohong Zhou, Xiangshan Ma, Yue Zhang, Yuanxing Waldor, Matthew K. Wang, Qiyao
- 机构：East China Univ Sci & Technol;Qingdao Natl Lab Marine Sci & Technol;East China Univ Sci & Technol;Univ Autonoma Barcelona;Brigham & Womens Hosp
- 来源：PLOS PATHOGENS 2018
- Involvement of LuxS in the regulation of motility and flagella biogenesis in Vibrio alginolyticus被引量：51收藏
- 作者：Tian, Yang Wang, Qiyao Liu, Qin Ma, Yue Cao, Xiaodan Guan, Lingyu Zhang, Yuanxing
- 机构： State Key Laboratory of Bioreactor Engineering
- 来源：Bioscience, Biotechnology and Biochemistry 2008
- 关键词：Bacteria - Bioassay - Gene expression - Real time control
- Role of RpoS in stress survival, synthesis of extracellular autoinducer 2, and virulence in Vibrio alginolyticus被引量：44收藏
- 作者：Tian, Yang Wang, Qiyao Liu, Qin Ma, Yue Cao, Xiaodan Zhang, Yuanxing
- 机构：E China Univ Sci & Technol
- 来源：ARCHIVES OF MICROBIOLOGY 2008
- 关键词：RpoS Vibrio alginolyticus stress AI-2 synthesis ECP
- Involvement of LuxS in the regulation of motility and flagella biogenesis in Vibrio alginolyticus被引量：42收藏
- 作者：Tian, Yang Wang, Qiyao Liu, Qin Ma, Yue Cao, Xiaodan Guan, Lingyu Zhang, Yuanxing
- 机构：E China Univ Sci & Technol
- 来源：BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY 2008
- 关键词：flagella LuxS motility quorum sensing Vibrio alginolyticus
- LuxO controls extracellular protease, haemolytic activities and siderophore production in fish pathogen Vibrio alginolyticus被引量：38收藏
- 作者：Wang, Q. Liu, Q. Ma, Y. Rui, H. Zhang, Y.
- 机构： State Key Laboratory of Bioreactor Engineering; State Key Laboratory of Bioreactor Engineering
- 来源：Journal of Applied Microbiology 2007
- 关键词：Cloning - Fish - Physiology
- A Bacterial Pathogen Senses Host Mannose to Coordinate Virulence被引量：31收藏
- 作者：Wei, Lifan Qiao, Haoxian Sit, Brandon Yin, Kaiyu Yang, Guanhua Ma, Ruiqing Ma, Jiabao Yang, Chun Yao, Jun Ma, Yue Xiao, Jingfan Liu, Xiaohong Zhang, Yuanxing Waldor, Matthew K. Wang, Qiyao
- 机构：East China Univ Sci & Technol;Qingdao Natl Lab Marine Sci & Technol;Shanghai Engn Res Ctr Maricultured Anim Vaccines;Brigham & Womens Hosp;Harvard Med Sch
- 来源：ISCIENCE 2019
- Complete sequence of virulence plasmid pEIB1 from the marine fish pathogen Vibrio anguillarum strain MVM425 and location of its replication region被引量：28收藏
- 作者：Wu, H Ma, Y Zhang, Y Zhang, H
- 机构：E China Univ Sci & Technol
- 来源：JOURNAL OF APPLIED MICROBIOLOGY 2004
- 关键词：genetic organization pEIB1 plasmid replication region Vibrio anguillarum
- Secretory delivery of heterologous proteins in attenuated Vibrio anguillarum for potential use in vaccine design被引量：28收藏
- 作者：Zhou, Lingyun Liu, Qin Wang, Qiyao Ma, Yue Xu, Yuzhou Yang, Zhao Zhao, Yan Zhang, Yuanxing
- 机构： State Key Laboratory of Bioreactor Engineering
- 来源：Applied Microbiology and Biotechnology 2008
- 关键词：Escherichia coli - Antigens - Peptides - Blood - Fluorescence
- Serine/threonine kinase PpkA coordinates the interplay between T6SS2 activation and quorum sensing in the marine pathogen Vibrio alginolyticus被引量：28收藏
- 作者：Yang, Zhen Zhou, Xiaohui Ma, Yue Zhou, Mian Waldor, Matthew K. Zhang, Yuanxing Wang, Qiyao
- 机构：East China Univ Sci & Technol;Qingdao Natl Lab Marine Sci & Technol;Shanghai Engn Res Ctr Maricultured Anim Vaccines;Univ Connecticut;Harvard Med Sch
- 来源：ENVIRONMENTAL MICROBIOLOGY 2018
- Biosynthesis and uptake of glycine betaine as cold-stress response to low temperature in fish pathogen Vibrio anguillarum被引量：26收藏
- 作者：Ma, Yue Wang, Qiyao Gao, Xiating Zhang, Yuanxing
- 机构：East China Univ Sci & Technol;Shanghai Engn Res Ctr Maricultured Anim Vaccines;Shanghai Collaborat Innovat Ctr Biomfg
- 来源：JOURNAL OF MICROBIOLOGY 2017
- 关键词：compatible solute glycine betaine protectant cold-stress Vibrio anguillarum
- Isolation, sequencing and characterization of cluster genes involved in the biosynthesis and utilization of the siderophore of marine fish pathogen Vibrio alginolyticus被引量：26收藏
- 作者：Wang, Qiyao Liu, Qin Ma, Yue Zhou, Lingyun Zhang, Yuanxing
- 机构：E China Univ Sci & Technol
- 来源：ARCHIVES OF MICROBIOLOGY 2007
- 关键词：Vibrio alginolyticus siderophore biosynthesis uptake cluster gene plasposon
- VqsA, a Novel LysR-Type Transcriptional Regulator, Coordinates Quorum Sensing (QS) and Is Controlled by QS To Regulate Virulence in the Pathogen Vibrio alginolyticus被引量：25收藏
- 作者：Gao, Xiating Wang, Xuetong Mao, Qiaoqiao Xu, Rongjing Zhou, Xiaohui Ma, Yue Liu, Qin Zhang, Yuanxing Wang, Qiyao
- 机构：East China Univ Sci & Technol;Shanghai Engn Res Ctr Maricultured Anim Vaccines;Univ Connecticut;Yangzhou Univ;Yantai Tianyuan Aquat Co Ltd
- 来源：APPLIED AND ENVIRONMENTAL MICROBIOLOGY 2018
- 关键词：Vibrio alginolyticus quorum sensing LuxR AphA VqsA virulence bacterial one-hybrid assay MQSR
- Stationary phase-dependent accumulation of ectoine is an efficient adaptation strategy in Vibrio anguillarum against cold stress被引量：24收藏
- 作者：Ma, Yue Wang, Qiyao Xu, Wensheng Liu, Xiaohong Gao, Xiating Zhang, Yuanxing
- 机构：East China Univ Sci & Technol;Shanghai Engn Res Ctr Maricultured Anim Vaccines;Shanghai Collaborat Innovat Ctr Biomfg;Beijing Univ Agr
- 来源：MICROBIOLOGICAL RESEARCH 2017
- 关键词：Vibrio anguillarum Compatible solutes Ectoine ectABC proVWX Cold adaptation
- A live attenuated Vibrio anguillarum vaccine induces efficient immunoprotection in Tiger puffer (Takifugu rubripes)被引量：24收藏
- 作者：Liu, Xiaohong Jiao, Chenglong Ma, Yue Wang, Qiyao Zhang, Yuanxing
- 机构：East China Univ Sci & Technol;Shanghai Engn Res Ctr Maricultured Anim Vaccines;Shanghai Collaborat Innovat Ctr Biomfg
- 来源：VACCINE 2018
- 关键词：Live attenuated Vibrio anguillarum Tiger puffer Vibriosis Efficient immunoprotection
- Roles of virulence regulator ToxR in viable but non-culturable formation by controlling reactive oxygen species resistance in pathogen Vibrio alginolyticus被引量：24收藏
- 作者：Zhou, Mengqing Huang, Yuping Zhang, Yuanxing Wang, Qiyao Ma, Yue Shao, Shuai
- 机构：East China Univ Sci & Technol;Southern Marine Sci & Engn Guangdong Lab Zhuhai;Shanghai Engn Res Ctr Maricultured Anim Vaccines
- 来源：MICROBIOLOGICAL RESEARCH 2022
- 关键词：VBNC Vibrio alginolyticus ToxR Virulence ROS
- Alternative Sigma Factor RpoX Is a Part of the RpoE Regulon and Plays Distinct Roles in Stress Responses, Motility, Biofilm Formation, and Hemolytic Activities in the Marine Pathogen Vibrio alginolyticus被引量：23收藏
- 作者：Gu, Dan Zhang, Jun Hao, Yuan Xu, Rongjing Zhang, Yuanxing Ma, Yue Wang, Qiyao
- 机构：East China Univ Sci & Technol;Shanghai Engn Res Ctr Maricultured Anim Vaccines;Yangzhou Univ;Yantai Tianyuan Aquat Co & Td
- 来源：APPLIED AND ENVIRONMENTAL MICROBIOLOGY 2019
- 关键词：ChIP-seq RNA-seq RpoE RpoX Vibrio alginolyticus virulence
- Binding site profiles and N-terminal minor groove interactions of the master quorum-sensing regulator LuxR enable flexible control of gene activation and repression被引量：22收藏
- 作者：Zhang, Jun Liu, Bing Gu, Dan Hao, Yuan Chen, Mo Ma, Yue Zhou, Xiaohui Reverter, David Zhang, Yuanxing Wang, Qiyao
- 机构：East China Univ Sci & Technol;Qingdao Natl Lab Marine Sci & Technol;Southern Marine Sci & Engn Guangdong Lab Zhuhai;Shanghai Engn Res Ctr Maricultured Anim Vaccines;Univ Autonoma Barcelona
- 来源：NUCLEIC ACIDS RESEARCH 2021
- 利用Berthelot颜色法测定发酵液中铵离子的干扰排除被引量：19收藏
- 作者：马悦 朱贻华 赵东玲 张元兴
- 机构：华东理工大学生物反应器工程国家重点实验室
- 来源：《华东理工大学学报（自然科学版）》 2006
- 关键词：Berthelot颜色反应 亚硫酸钠 次氯酸钠 铵离子测定
- 摘要：在利用Berthelot反应测定微生物发酵中铵离子浓度时,培养液中的亚硫酸钠严重干扰了测定结果。预先加入适量的次氯酸钠溶液处理样品能有效地排除这一干扰。对次氯酸钠的加入量、处理时间和待测样品的pH进行优化,结果表明:当次...
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- MviN mediates the regulation of environmental osmotic pressure on esrB to control the virulence in the marine fish pathogen Edwardsiella piscicida被引量：19收藏
- 作者：Yin, Kaiyu Zhang, Jin Ma, Jiabao Jin, Peng Ma, Yue Zhang, Yuanxing Liu, Xiaohong Wang, Qiyao
- 机构：East China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol;Shanghai Engn Res Ctr Maricultured Anim Vaccines
- 来源：MICROBIOLOGICAL RESEARCH 2020
- 关键词：Edwardsiella piscicida EsrB Lipid II flippase Osmotic pressure In vivo colonization
- Gene cloning, expression and functional characterization of a phosphopantetheinyl transferase from Vibrio anguillarum serotype O1被引量：18收藏
- 作者：Liu, Q Ma, Y Zhou, LY Zhang, YX
- 机构：E China Univ Sci & Technol
- 来源：ARCHIVES OF MICROBIOLOGY 2005
- 关键词：Vibrio anguillarrum angD gene phosphopantetheinyl transferase carrier protein post-translational modification
- PepA binds to and negatively regulates esrB to control virulence in the fish pathogen Edwardsiella piscicida被引量：17收藏
- 作者：Yin, Kaiyu Peng, Yue Ahmed, Moamer A. H. Ma, Jiabao Xu, Rongjing Zhang, Yuanxing Ma, Yue Wang, Qiyao
- 机构：East China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol;Shanghai Engn Res Ctr Maricultured Anim Vaccines;Yantai Tianyuan Aquat Co Ltd
- 来源：MICROBIOLOGICAL RESEARCH 2020
- 关键词：Edwardsiella piscicida Pull-down EsrB Leucyl aminopeptidase In vivo colonization
- Freeze-drying of live attenuated Vibrio anguillarum mutant for vaccine preparation被引量：16收藏
- 作者：Yang, Lu Ma, Yue Zhang, Yuanxing
- 机构：E China Univ Sci & Technol
- 来源：BIOLOGICALS 2007
- 关键词：freeze-drying Vibrio anguillarum protectant viability vaccine
- Cloning, identification and expression of an entE homologue angE from Vibrio anguillarum serotype O1被引量：15收藏
- 作者：Liu, Q Ma, Y Wu, HZ Shao, MF Liu, HF Zhang, YX
- 机构：E China Univ Sci & Technol
- 来源：ARCHIVES OF MICROBIOLOGY 2004
- 关键词：Vibrio anguillarrum pJM1-like plasmid iron uptake system angE 2,3-DHBA-AMP ligase Anguibactin biosynthesis gene expression
- Complete genome sequence of the marine fish pathogen Vibrio anguillarum and genome-wide transposon mutagenesis analysis of genes essential for in vivo infection被引量：15收藏
- 作者：Yang Guanhua Wang, Cheng Wang, Xuetong Ma, Ruiqing Zheng, Huajun Liu, Qin Zhang, Yuanxing Ma, Yue Wang, Qiyao
- 机构：East China Univ Sci & Technol;Qingdao Natl Lab Marine Sci & Technol;Shanghai Engn Res Ctr Maricultured Anim Vaccines;Chinese Natl Human Genome Ctr Shanghai
- 来源：MICROBIOLOGICAL RESEARCH 2018
- 关键词：Genome sequence Tn-seq Vibrio anguillarum In vivo fitness Conditionally essential genes
- 鳗弧菌减毒活疫苗对牙鲆免疫效果的研究被引量：13收藏
- 作者：潘燕华 马悦 赵东玲 孙修勤 王启要 吴海珍 张元兴
- 机构：华东理工大学生物反应器工程国家重点实验室;国家海洋局第一海洋研究所
- 来源：《食品与药品》 2009
- 关键词：免疫 减毒活疫苗 鳗弧菌 牙鲆
- 摘要：目的研究鳗弧菌减毒活疫苗对牙鲆的免疫保护作用。方法以鳗弧菌野生菌全细胞灭活疫苗为对照,用肌内注射和浸泡免疫方式分析鳗弧菌减毒活疫苗对牙鲆的免疫保护作用。结果不同疫苗和免疫方式的受免鱼各免疫指标均有明显变化,以注射减毒活疫...
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- 海洋鱼病疫苗开发与生物反应器大规模生产被引量：13收藏
- 作者：张元兴 马悦 孙修勤
- 机构：华东理工大学生物反应器工程国家重点实验室;国家海洋局第一海洋研究所
- 来源：《高技术通讯》 2000
- 关键词：海水养殖 鱼病 疫苗开发 生物反应器
- 摘要：鉴于海水养殖鱼类的经济特点和基因工程菌环境安全性的潜在风险,以现代生物反应器高密度培养技术和非基因工程手段代谢调控为技术特征的海洋鱼类疫苗研究开发将成为目前鱼病控制的及时、有效和安全的发展策略。本文就最新国内外发展动态进...
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