成果/Result
- Chemo- and Regioselective Organo-Photoredox Catalyzed Hydroformylation of Styrenes via a Radical Pathway被引量：119收藏
- 作者：Huang, He Yu, Chenguang Zhang, Yueteng Zhang, Yongqiang Mariano, Patrick S. Wang, Wei
- 机构：Univ New Mexico;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 2017
- 关键词：Carboxylation - Catalysis - Regioselectivity - Hydroformylation - Free radicals - Styrene
- Direct Cα-heteroarylation of structurally diverse ethers via a mild N-hydroxysuccinimide mediated cross-dehydrogenative coupling reaction被引量：89收藏
- 作者：Liu, Shihui Liu, Aoxia Zhang, Yongqiang Wang, Wei
- 机构：East China Univ Sci & Technol;Univ New Mexico
- 来源：CHEMICAL SCIENCE 2017
- 关键词：Free radical reactions - Atoms
- Synthesis of Z-alkenes via visible light promoted photocatalytic E → Z isomerization under metal-free conditions被引量：76收藏
- 作者：Cai, Wenbin Fan, Huaqiang Ding, Dazhong Zhang, Yongqiang Wang, Wei
- 机构：East China Univ Sci & Technol;Qingdao Inst Food & Drug Control;Univ New Mexico
- 来源：CHEMICAL COMMUNICATIONS 2017
- Photocatalytic C-H silylation of heteroarenes by using trialkylhydrosilanes被引量：76收藏
- 作者：Liu, Shihui Pan, Peng Fan, Huaqiang Li, Hao Wang, Wei Zhang, Yongqiang
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Univ Arizona
- 来源：CHEMICAL SCIENCE 2019
- 关键词：Chemical stability
- Highly stereoselective synthesis of aryl/heteroaryl-C-nucleosides via the merger of photoredox and nickel catalysis被引量：69收藏
- 作者：Yingying Liu, Shihui Xi, Yifan Li, Hongrui Yang, Kai Cheng, Zhihao Wang, Wei Zhang, Yongqiang
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Jiaxing Univ;Univ Arizona;Univ Arizona
- 来源：CHEMICAL COMMUNICATIONS 2019
- Synthesis of β-Silyl α-Amino Acids via Visible-Light-Mediated Hydrosilylation被引量：51收藏
- 作者：Wan, Yi Zhu, Jiajie Yuan, Qiyang Wang, Wei Zhang, Yongqiang
- 机构：East China Univ Sci & Technol;Univ Arizona;Univ Arizona
- 来源：ORGANIC LETTERS 2021
- Synthesis of Aldehydes by Organocatalytic Formylation Reactions of Boronic Acids with Glyoxylic Acid被引量：49收藏
- 作者：Huang, He Yu, Chenguang Li, Xiangmin Zhang, Yongqiang Zhang, Yueteng Chen, Xiaobei Mariano, Patrick S. Xie, Hexin Wang, Wei
- 机构：Univ New Mexico;East China Univ Sci Technol;East China Univ Sci Technol
- 来源：ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 2017
- 关键词：arenes boron formylation organocatalysis synthetic methods
- Imaging the dynamics of messenger RNA with a bright and stable green fluorescent RNA被引量：42收藏
- 作者：Zuo, Fangting Jiang, Li Su, Ni Zhang, Yaqiang Bao, Bingkun Wang, Limei Shi, Yajie Yang, Huimin Huang, Xinyi Li, Ruilong Zeng, Qingmei Chen, Zhengda Lin, Qiuning Zhuang, Yingping Zhao, Yuzheng Chen, Xianjun Zhu, Linyong Yang, Yi
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Shanghai Jiao Tong Univ;East China Univ Sci & Technol;Chinese Acad Med Sci
- 来源：NATURE CHEMICAL BIOLOGY 2024
- Synthesis of 2-Quinolinones via a Hypervalent Iodine(III)-Mediated Intramolecular Decarboxylative Heck-Type Reaction at Room Temperature被引量：40收藏
- 作者：Fan, Huaqiang Pang, Peng Zhang, Yongqiang Wang, Wei
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Univ Arizona
- 来源：ORGANIC LETTERS 2018
- Structure-Based Optimization of Small-Molecule Inhibitors for the β-Catenin/B-Cell Lymphoma 9 Protein-Protein Interaction被引量：34收藏
- 作者：Zhang, Min Wang, Zhen Zhang, Yongqiang Guo, Wenxing Ji, Haitao
- 机构：H Lee Moffitt Canc Ctr & Res Inst;Univ S Florida;Univ S Florida;East China Univ Sci & Technol;Univ Utah
- 来源：JOURNAL OF MEDICINAL CHEMISTRY 2018
- Organophotocatalytic silyl transfer of silylboranes enabled by methanol association: a versatile strategy for C-Si bond construction被引量：31收藏
- 作者：Wan, Yi Zhao, Yumo Zhu, Jiajie Yuan, Qiyang Wang, Wei Zhang, Yongqiang
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Univ Arizona;Univ Arizona
- 来源：GREEN CHEMISTRY 2023
- Highly Stereoselective C-Glycosylation by Photocatalytic Decarboxylative Alkynylation on Anomeric Position: A Facile Access to Alkynyl C-Glycosides被引量：30收藏
- 作者：Lu, KaiLin Ma, Yingying Liu, Shihui Guo, Shixun Zhang, Yongqiang
- 机构：East China Univ Sci & Technol;Jiaxing Univ
- 来源：CHINESE JOURNAL OF CHEMISTRY 2022
- 关键词：Photocatalysis Anomeric position Decarboxylative alkynylation C-C coupling Glycosides
- A photoredox/nickel dual-catalytic strategy for benzylic C-H alkoxylation被引量：28收藏
- 作者：Dong, Min Jia, Yuqi Zhou, Wei Gao, Jinlai Lv, Xiaoqing Luo, Fan Zhang, Yongqiang Liu, Shihui
- 机构：Jiaxing Univ;East China Univ Sci & Technol
- 来源：ORGANIC CHEMISTRY FRONTIERS 2021
- 关键词：Synthesis (chemical) - Nickel compounds - Ethers
- Graphitic Carbon Nitride Polymer as a Recyclable Photoredox Catalyst for Decarboxylative Alkynylation of Carboxylic Acids被引量：27收藏
- 作者：Guo, Jiaqi Wang, Yating Li, Yuhang Lu, Kailin Liu, Shihui Wang, Wei Zhang, Yongqiang
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;Univ Arizona;Univ Arizona
- 来源：ADVANCED SYNTHESIS & CATALYSIS 2020
- 关键词：graphitic carbon nitride heterogeneous photoredox catalysis decarboxylative alkynylation sustainable synthesis
- Photocatalytic C-Si Bond Formations Using Pentacoordinate Silylsilicates as Silyl Radical Precursors: Synthetic Tricks Using Old Reagents被引量：22收藏
- 作者：Zhao, Yumo Wan, Yi Yuan, Qiyang Wei, Jinlian Zhang, Yongqiang
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：ORGANIC LETTERS 2023
- PIFA-Mediated Cross-Dehydrogenative Coupling of N-Heteroarenes with Cyclic Ethers: Ethanol as an Efficient Promoter被引量：20收藏
- 作者：Li, Xiang Liu, Chaoyang Guo, Shixun Wang, Wei Zhang, Yongqiang
- 机构：East China Univ Sci & Technol;Univ Arizona;Univ Arizona
- 来源：EUROPEAN JOURNAL OF ORGANIC CHEMISTRY 2021
- 关键词：Cross-dehydrogenative coupling Cyclic ethers Ethanol PIFA Visible Light
- New triazole derivatives containing substituted 1,2,3-triazole side chains: Design, synthesis and antifungal activity被引量：19收藏
- 作者：Chen, Hai-Jiang Jiang, Yan-Juan Zhang, Yong-Qiang Jing, Qi-Wei Liu, Na Wang, Yan Zhang, Wan-Nian Sheng, Chun-Quan
- 机构：Fujian Univ Tradit Chinese Med;Second Mil Med Univ;East China Univ Sci & Technol
- 来源：CHINESE CHEMICAL LETTERS 2017
- 关键词：Triazole derivatives Antifungal activities Click reaction Molecular docking CYP51
- Inhibition of mitochondrial complex III induces differentiation in acute myeloid leukemia被引量：15收藏
- 作者：Zhang, Youping Luo, Ting Ding, Xinyu Chang, YungTing Liu, Chuanxu Zhang, Yongqiang Hao, Siguo Yin, Qianqian Jiang, Biao
- 机构：Shanghai Jiao Tong Univ;East China Univ Sci & Technol;ShanghaiTech Univ;Shanghai Jiao Tong Univ;Chinese Acad Sci
- 来源：BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 2021
- 关键词：Acute myeloid leukemia Differentiation therapy Mitochondrial ETC complex III Pyrimidine biosynthesis
- Discovery and optimization of betulinic acid derivatives as novel potent CD73 inhibitors被引量：14收藏
- 作者：Zhang, Yanming Ye, Shuang Wang, Yuan Wang, Chuanhao Zhu, Yazhao Wu, Yuelin Zhang, Yongqiang Zhang, Huojun Miao, Zhenyuan
- 机构：Second Mil Med Univ;East China Univ Sci & Technol;Ningxia Med Univ;Shanghai Inst Technol;Second Mil Med Univ
- 来源：BIOORGANIC & MEDICINAL CHEMISTRY 2022
- 关键词：Drug discovery CD73 Betulinic acid Immuno-oncology
- A cascade approach to 3D cyclic carbamates via an ionic decarboxylative functionalization of olefinic oxamic acids被引量：14收藏
- 作者：Fan, Huaqiang Wan, Yi Pan, Peng Cai, Wenbin Liu, Shihui Liu, Chuanxu Zhang, Yongqiang
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Shanghai Jiao Tong Univ
- 来源：CHEMICAL COMMUNICATIONS 2020
- Synthesis of novel azabicyclo derivatives containing a thiazole moiety and their biological activity against pine-wood nematodes被引量：10收藏
- 作者：Li, Hui Lu, Aoyun Zhang, Yanqiu Peng, Yanqing Song, Gonghua
- 机构：East China Univ Sci & Technol
- 来源：PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS 2020
- 关键词：Azabicyclo PWNs nematicidal activity novel nematicide
- Photoredox/Nickel Dual-Catalytic Asymmetric Silylarylation of Alkenes被引量：8收藏
- 作者：Yuan, Qiyang Deng, Zhengrong Wan, Yi Zhang, Yongqiang
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：ORGANIC LETTERS 2025
- Spatiotemporal control of RNA metabolism and CRISPR-Cas functions using engineered photoswitchable RNA-binding proteins被引量：7收藏
- 作者：Liu, Renmei Yao, Jing Zhou, Siyu Yang, Jing Zhang, Yaqiang Yang, Xiaoyan Li, Leshi Zhang, Yunbin Zhuang, Yingping Yang, Yi Chen, Xianjun
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;Chinese Acad Sci
- 来源：NATURE PROTOCOLS 2024
- Targeting Bcl-xL is a potential therapeutic strategy for extranodal NK/T cell lymphoma被引量：6收藏
- 作者：Liu, Chuanxu Ding, Xinyu Li, Gaoyang Zhang, Youping Shao, Yubao Liu, Linyi Zhang, Wenhao Ma, Yujie Guan, Wenbin Wang, Lifeng Xu, Zhongli Chang, YungTing Zhang, Yongqiang Jiang, Biao Yin, Qianqian Tao, Rong
- 机构：Fudan Univ;ShanghaiTech Univ;Shanghai Jiao Tong Univ;Shanghai Jiao Tong Univ;Shanghai Jiao Tong Univ
- 来源：ISCIENCE 2023
- Tamsulosin ameliorates bone loss by inhibiting the release of Cl- through wedging into an allosteric site of TMEM16A被引量：6收藏
- 作者：Li, Shiliang Sun, Weijia Li, Shuang Zhu, Lili Guo, Shuai He, Jiaqi Li, Yuheng Tian, Chaoquan Zhao, Zhenjiang Yu, Tao Li, Jianwei Zhang, Yiqing Hai, Youlong Wang, Jiawen Zheng, Yongjun Wang, Rui Hu, Xiaoyong Ling, Shukuan Li, Honglin Li, Yingxian
- 机构：East China Normal Univ;East China Univ Sci & Technol;Fudan Univ;China Astronaut Res & Training Ctr;Beijing Inst Technol
- 来源：PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 2025
- 关键词：TMEM16A Tamsulosin allosteric site bone loss
- TfOH-Catalyzed Cascade Reaction: Metal-Free Access to 3,3-Disubstituted Phthalides from o-Alkynylbenzoic Acids被引量：6收藏
- 作者：Zhang, Yanqiu Zhang, Zhiliang Xia, Yunxin Wang, Jiayi Peng, Yanqing Song, Gonghua
- 机构：East China Univ Sci & Technol
- 来源：JOURNAL OF ORGANIC CHEMISTRY 2023
- 关键词：Cyclization - Regioselectivity
- A novel metal-free synthesis of thiazole-substituted α-hydroxy carbonyl compounds and 2-alkenylthiazoles from thiazole N-oxides and olefins被引量：6收藏
- 作者：Li, Hui Zhang, Juan Zhang, Yanqiu Wang, Jiayi Song, Gonghua
- 机构：East China Univ Sci & Technol
- 来源：TETRAHEDRON LETTERS 2019
- 关键词：Metal-free Thiazole N-oxide 1, 3-Dipolar cycloaddition Thiazole-substituted alpha-hydroxy carbonyl
- Radical-Chain Hydrosilylation of Alkenes Enabled by Triplet Energy Transfer被引量：6收藏
- 作者：Guo, Shixun Wang, Wei Zhang, Yongqiang
- 机构：Shanghai Frontiers Sci Ctr Optogenet Tech Cell Met;East China Univ Sci & Technol;Univ Arizona;Univ Arizona
- 来源：CHEMISTRY-A EUROPEAN JOURNAL 2024
- 关键词：Radical-chain reaction Hydrosilylation Alkenes Triplet energy transfer
- Discovery of a novel SHP2 allosteric inhibitor using virtual screening, FMO calculation, and molecular dynamic simulation被引量：5收藏
- 作者：Yuan, Zhen Zhang, Manzhan Chang, Longfeng Chen, Xingyu Ruan, Shanshan Shi, Shanshan Zhang, Yiqing Zhu, Lili Li, Honglin Li, Shiliang
- 机构：East China Univ Sci & Technol;East China Normal Univ;Lingang Lab
- 来源：JOURNAL OF MOLECULAR MODELING 2024
- 关键词：SHP2 Allosteric inhibitor Fragment molecular orbital method Virtual screening Molecular dynamics simulation
- Enantioselective organocatalytic Michael addition of isorhodanines to α,β-unsaturated aldehydes被引量：5收藏
- 作者：Wu, Shanchao Li, Yu Zhang, Yongqiang Fang, Kun Dong, Guoqiang Liu, Na Miao, Zhenyuan Yao, Jianzhong Wang, Wei Zhang, Wannian Sheng, Chunquan
- 机构：Second Mil Med Univ;E China Univ Sci & Technol;Univ New Mexico
- 来源：ORGANIC & BIOMOLECULAR CHEMISTRY 2016
- 关键词：Addition reactions - Aldehydes
