成果/Result
- Ivermectin induces cell cycle arrest and apoptosis of HeLa cells via mitochondrial pathway被引量：72收藏
- 作者：Zhang, Ping Zhang, Yang Liu, Kuikui Liu, Bin Xu, Wenping Gao, Jufang Ding, Lei Tao, Liming
- 机构：East China Univ Sci & Technol;Shandong Acad Pharmaceut Sci;Vegetable Tech Extens Stn Qingpu Dist Shanghai;Shanghai Normal Univ
- 来源：CELL PROLIFERATION 2019
- 关键词：antimigratory effects apoptosis cell cycle arrest cervical cancer ivermectin mitochondrial pathway
- Avermectin Confers Its Cytotoxic Effects by Inducing DNA Damage and Mitochondria-Associated Apoptosis被引量：56收藏
- 作者：Zhang, Yang Luo, Mingming Xu, Wenping Yang, Mingjun Wang, Bo Gao, Jufang Li, Yaxiao Tao, Liming
- 机构：East China Univ Sci & Technol;Shanghai Normal Univ;Univ Bath
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2016
- 关键词：avermectin cytotoxic effects DNA damage apoptosis mitochondrial pathway
- Characterization of glyphosate-induced cardiovascular toxicity and apoptosis in zebrafish被引量：55收藏
- 作者：Lu, Jian Wang, Weiguo Zhang, Cheng Xu, Wenping Chen, Weidong Tao, Liming Li, Zhong Cheng, Jiagao Zhang, Yang
- 机构：East China Univ Sci & Technol;UT southwestern Med Ctr
- 来源：SCIENCE OF THE TOTAL ENVIRONMENT 2022
- 关键词：Glyphosate Developmental toxicity Heart Vascular Apoptosis Zebra fish
- Cytotoxic effects of Avermectin on human HepG2 cells in vitro bioassays被引量：51收藏
- 作者：Zhang, Yang Wu, Jigang Xu, Wenping Gao, Jufang Cao, Haijing Yang, Mingjun Wang, Bo Hao, Youwu Tao, Liming
- 机构：East China Univ Sci & Technol;Shanghai Normal Univ
- 来源：ENVIRONMENTAL POLLUTION 2017
- 关键词：Environmental toxicity Pesticide Avermectin HepG2 cells Cytotoxic effects Mitochondrial-mediated apoptosis
- Spinosad induces programmed cell death involves mitochondrial dysfunction and cytochrome C release in Spodoptera frugiperda Sf9 cells被引量：51收藏
- 作者：Yang, Mingjun Wang, Bo Gao, Jufang Zhang, Yang Xu, Wenping Tao, Liming
- 机构：East China Univ Sci & Technol;Shanghai Normal Univ
- 来源：CHEMOSPHERE 2017
- 关键词：Spinosad Programmed cell death Mitochondrial dysfunction Cytochrome C release
- Natural pyrethrins induces apoptosis in human hepatocyte cells via Bax- and Bcl-2-mediated mitochondrial pathway被引量：48收藏
- 作者：Yang, Yun Zong, Mimi Xu, Wenping Zhang, Yang Wang, Bo Yang, Mingjun Tao, Liming
- 机构：East China Univ Sci & Technol
- 来源：CHEMICO-BIOLOGICAL INTERACTIONS 2017
- 关键词：Natural pyrethrins Cytotoxic effects Human hepatocyte cells Apoptosis The mitochondrial pathway
- Distinct immunosuppressive effect by Isodon serra extracts被引量：47收藏
- 作者：Zhang, Y Liu, JW Jia, W Zhao, AH Li, T
- 机构：E China Univ Sci & Technol;Shanghai Jiao Tong Univ
- 来源：INTERNATIONAL IMMUNOPHARMACOLOGY 2005
- 关键词：immunosuppression Concanavalin A flow cytometry analyses interleukin-2
- Induction of developmental toxicity and cardiotoxicity in zebrafish embryos by Emamectin benzoate through oxidative stress被引量：46收藏
- 作者：Lu, Jian Wang, Weiguo Xu, Wenping Zhang, Chenggong Zhang, Cheng Tao, Liming Li, Zhong Zhang, Yang
- 机构：East China Univ Sci & Technol;Shanghai Municipal Bur Publ Secur;UT Southwestern Med Ctr
- 来源：SCIENCE OF THE TOTAL ENVIRONMENT 2022
- 关键词：Emamectin benzoate Developmental toxicity Oxidative stress Cardiotoxicity Zebrafish
- Design and synthesis of small molecular dual inhibitor of falcipain-2 and dihydrofolate reductase as antimalarial agent被引量：43收藏
- 作者：Huang, Huang Lu, Weiqiang Li, Xi Cong, Xiaoli Ma, Hongmei Liu, Xiaofeng Zhang, Yu Che, Peng Ma, Ruoqun Li, Honglin Shen, Xu Jiang, Hualiang Huang, Jin Zhu, Jin
- 机构：E China Univ Sci & Technol;Minsheng Pharma;Chinese Acad Sci
- 来源：BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 2012
- 关键词：Falcipain-2 Dihydrofolate reductase Dual inhibitor Antimalarial drug SAR Molecular docking
- Difenoconazole induces oxidative DNA damage and mitochondria mediated apoptosis in SH-SY5Y cells被引量：42收藏
- 作者：Wang, Xin Ni, Hongfei Xu, Wenping Wu, Bing Xie, Te Zhang, Cheng Cheng, Jiagao Li, Zhong Tao, Liming Zhang, Yang
- 机构：East China Univ Sci & Technol;UT Southwestern Med Ctr
- 来源：CHEMOSPHERE 2021
- 关键词：Difenoconazole Cytotoxicity DNA damage Apoptosis Human neuroblastoma SH-SY5Y cells
- Natural pyrethrins induce autophagy of HepG2 cells through the activation of AMPK/mTOR pathway被引量：38收藏
- 作者：Yang, Yun Gao, Jufang Zhang, Yang Xu, Wenping Hao, Youwu Xu, Zhiping Tao, Liming
- 机构：East China Univ Sci & Technol;Shanghai Normal Univ
- 来源：ENVIRONMENTAL POLLUTION 2018
- 关键词：Natural pyrethrins Autophagy HepG2 cells Oxidative stress AMPK/mTOR pathway
- Evaluation of the cytotoxic effects of glyphosate herbicides in human liver, lung, and nerve被引量：37收藏
- 作者：Hao, Youwu Zhang, Yang Ni, Hongfei Gao, Jufang Yang, Yun Xu, Wenping Tao, Liming
- 机构：East China Univ Sci & Technol;Shanghai Normal Univ
- 来源：JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART B-PESTICIDES FOOD CONTAMINANTS AND AGRICULTURAL WASTES 2019
- 关键词：Cytotoxicity ethoxylated formulant glyphosate herbicide human health pesticide
- Roundup? confers cytotoxicity through DNA damage and Mitochondria-Associated apoptosis induction被引量：32收藏
- 作者：Hao, Youwu Chen, Hui Xu, Wenping Gao, Jufang Yang, Yun Zhang, Yang Tao, Liming
- 机构：East China Univ Sci & Technol;Shanghai Normal Univ
- 来源：ENVIRONMENTAL POLLUTION 2019
- 关键词：Glyphosate-based herbicide Cytotoxicity DNA damage Mitochondria-associated apoptosis Human health risk
- Reversible Regulation of Succinate Dehydrogenase by Tools of Photopharmacology被引量：28收藏
- 作者：Fu, Wen Shao, Zhongli Sun, Xujuan Zhou, Cong Xu, Zhiping Zhang, Yang Cheng, Jiagao Li, Zhong Shao, Xusheng
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2022
- 关键词：regulation SDH photochromic ligands azobenzene optical control
- Synthesis of CF3-Containing Linear Nitriles from α-(Trifluoromethyl)styrenes被引量：26收藏
- 作者：Xu, Sixue Deng, Yupian He, Jingjing Zeng, Qanding Liu, Chuan Zhang, Yi Zhu, Bin Cao, Song
- 机构：East China Univ Sci & Technol ECUST
- 来源：ORGANIC LETTERS 2021
- Azo-incorporating Increases Inhibitory Activity of Succinate Dehydrogenase被引量：26收藏
- 作者：Fu, Wen Hu, Xinyue Yuan, Qinglong Sun, Xujuan Xu, Zhiping Zhang, Yang Cheng, Jiagao Ye, Yonghao Li, Zhong Shao, Xusheng
- 机构：East China Univ Sci & Technol;Nanjing Agr Univ;East China Univ Sci & Technol
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2021
- 关键词：azobenzene activity fungicide succinate dehydrogenase
- DBN-Mediated Addition Reaction of α-(Trifluoromethyl)styrenes with Diazoles, Triazoles, Tetrazoles, and Primary, Secondary, and Secondary Cyclic Amines被引量：26收藏
- 作者：He, Jingjing Liu, Chuan Deng, Yupian Zeng, Qianding Zhang, Yi Liu, Ying Zheng, Pai Cao, Song
- 机构：East China Univ Sci & Technol ECUST
- 来源：ORGANIC LETTERS 2022
- Avermectin induced DNA damage to the apoptosis and autophagy in human lung epithelial A549 cells被引量：26收藏
- 作者：Diao, Lin Tang, Ning Zhang, Cheng Cheng, Jiagao Zhang, Zhenhai Wang, Siyu Wu, Can Zhang, Lutong Tao, Liming Li, Zhong Zhang, Yang
- 机构：East China Univ Sci & Technol;UT Southwestern Med Ctr
- 来源：ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY 2021
- 关键词：Avermectin Cytotoxicity DNA damage Programmed cell death Human A549 cells
- Discovery of a Novel CCR5 Antagonist Lead Compound Through Fragment Assembly被引量：26收藏
- 作者：Liu, Yanqing Zhou, Enkun Yu, Kunqian Zhu, Jin Zhang, Yu Xie, Xin Li, Jian Jiang, Hualiang
- 机构：Chinese Acad Sci;E China Univ Sci & Technol;Southwest Univ;Chinese Acad Sci
- 来源：MOLECULES 2008
- 关键词：CCR5 antagonist fragment assembly HIV-1 molecular modeling
- Exposure to environmental concentrations of natural pyrethrins induces hepatotoxicity: Assessment in HepG2 cell lines and zebrafish models被引量：25收藏
- 作者：Lu, Jian Yang, Yun Zhu, Lianhua Li, Meng Xu, Wenping Zhang, Cheng Cheng, Jiagao Tao, Liming Li, Zhong Zhang, Yang
- 机构：East China Univ Sci & Technol;UT Southwestern Med Ctr
- 来源：CHEMOSPHERE 2022
- 关键词：Natural pyrethrins Hepatotoxicity Oxidative stress DNA damage Repair HepG2 cells Zebrafish
- Carboxyl-functional ionic liquids as scavengers: Case studies on benzyl chloride, amines, and methanesulfonyl chloride被引量：23收藏
- 作者：Cai, Yueqin Zhang, Ying Peng, Yanqing Lu, Feng Huang, Xinglong Song, Gonghua
- 机构：E China Univ Sci & Technol
- 来源：JOURNAL OF COMBINATORIAL CHEMISTRY 2006
- Spinetoram confers its cytotoxic effects by inducing AMPK/mTOR-mediated autophagy and oxidative DNA damage被引量：21收藏
- 作者：Zhang, Yang Guo, Wei Chen, Hui Gao, Jufang Xu, Zhiping Tao, Liming Li, Zhong Xu, Wenping
- 机构：East China Univ Sci & Technol;China Crop Protect Ind Assoc;Shanghai Normal Univ
- 来源：ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY 2019
- 关键词：Spinetoram Cytotoxic effects Mitochondrial dysfunction AMPK/mTOR-mediated autophagy Oxidative DNA damage
- The insecticide spinosad induces DNA damage and apoptosis in HEK293 and HepG2 cells被引量：21收藏
- 作者：Yang, Mingjun Xiang, Guanggang Li, Diqiu Zhang, Yang Xu, Wenping Tao, Liming
- 机构：East China Univ Sci & Technol
- 来源：MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS 2016
- 关键词：Spinosad DNA damage Comet assay H2AX foci Apoptosis Cytotoxic
- Pyrethrum-extract induced autophagy in insect cells: A new target?被引量：21收藏
- 作者：Xu, Zhiping Lu, Miaoqing Yang, Mingjun Xu, Wenping Gao, Jufang Zhang, Yang Yang, Yun Tao, Liming
- 机构：East China Univ Sci & Technol;Shanghai Normal Univ
- 来源：PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY 2017
- 关键词：Insecticide Pyrethrum-extract Sf9 cells Cytotoxicity Autophagy
- Staurosporine shows insecticidal activity against Mythimna separata Walker (Lepidoptera: Noctuidae) potentially via induction of apoptosis被引量：21收藏
- 作者：Zhang, Yang Liu, Songlin Yang, Xing Yang, Mingjun Xu, Wenping Li, Yaxiao Tao, Liming
- 机构：E China Univ Sci & Technol;Shanghai Pesticide Res Inst;Univ Bath
- 来源：PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY 2016
- 关键词：Insecticidal activity Staurosporine Mythimna separata Walker Apoptosis Sf9 cells The mitochondrial pathway
- Spinosad induces autophagy of Spodoptera frugiperda Sf9 cells and the activation of AMPK/mTOR signaling pathway被引量：21收藏
- 作者：Yang, Mingjun Hao, Youwu Gao, Jufang Zhang, Yang Xu, Wenping Tao, Liming
- 机构：East China Univ Sci & Technol;Shanghai Normal Univ
- 来源：COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY 2017
- 关键词：Spinosad Sf9 cells Autophagy AMPK mTOR
- Tebufenozide induces G1/S cell cycle arrest and apoptosis in human cells被引量：20收藏
- 作者：Xu, Wenping Wang, Bo Yang, Mingjun Zhang, Yang Xu, Zhiping Yang, Yun Cao, Haijing Tao, Liming
- 机构：East China Univ Sci & Technol
- 来源：ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY 2017
- 关键词：Pesticide Tebufenozide Cytotoxic effects DNA damage Cell cycle arrest Apoptosis
- Ivermectin confers its cytotoxic effects by inducing AMPK/mTOR-mediated autophagy and DNA damage被引量：20收藏
- 作者：Zhang, Ping Ni, Hongfei Zhang, Yang Xu, Wenping Gao, Jufang Cheng, Jiagao Tao, Liming
- 机构：East China Univ Sci & Technol;Shanghai Normal Univ
- 来源：CHEMOSPHERE 2020
- 关键词：Ivermectin Accumulated toxicity Cytotoxicity DNA damage Autophagy
- Systematic Analysis of the Multiple Bioactivities of Green Tea through a Network Pharmacology Approach被引量：20收藏
- 作者：Zhang, Shoude Shan, Lei Li, Qiao Wang, Xia Li, Shiliang Zhang, Yuan Fu, Jianjun Liu, Xiaofeng Li, Honglin Zhang, Weidong
- 机构：E China Univ Sci & Technol;Second Mil Med Univ
- 来源：EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE 2014
- Rice-fish co-culture promotes multiple ecosystem services supporting increased yields被引量：19收藏
- 作者：Li, Shuang-Xi Jiang, Jian Lv, Wei-Guang Siemann, Evan Woodcock, Ben A. Wang, Yu-Quan Cavalieri, Andrea Bai, Na-Ling Zhang, Juan-Qin Zheng, Xian-Qing Zhang, Han-Lin Zhang, Hai-Yun Zhang, Yue Wan, Nian-Feng
- 机构：East China Univ Sci & Technol;Shanghai Engn Res Ctr Low Carbon Agr;Fengxian Dist Agrotechnol Extens Ctr;Rice Univ;UK Ctr Ecol & Hydrol
- 来源：AGRICULTURE ECOSYSTEMS & ENVIRONMENT 2025
- 关键词：Biodiversity Distance effect Herbivore Migration hypothesis Predator Trophic cascade
