- Direct Asymmetric Synthesis of β-Bis-Aryl-α-Amino Acid Esters via Enantioselective Copper-Catalyzed Addition of p-Quinone Methides被引量：170收藏
- 作者：He, Fu-Sheng Jin, Jing-Hai Yang, Zhong-Tao Yu, Xingxin Fossey, John S. Deng, Wei-Ping
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol;Univ Birmingham
- 来源：ACS CATALYSIS 2016
- 关键词：unnatural alpha-amino acids asymmetric catalysis copper conjugate addition para-quinone methides
- 质疑
- Double carbometallation of alkynes: an efficient strategy for the construction of polycycles被引量：80收藏
- 作者：Luo, Yong Pan, Xiaolin Yu, Xingxin Wu, Jie
- 机构：Fudan Univ;E China Univ Sci & Technol;Chinese Acad Sci
- 来源：CHEMICAL SOCIETY REVIEWS 2014
- 质疑
- Highly Enantioselective Rhodium-Catalyzed Addition of Arylboroxines to Simple Aryl Ketones: Efficient Synthesis of Escitalopram被引量：78收藏
- 作者：Huang, Linwei Zhu, Jinbin Jiao, Guangjun Wang, Zheng Yu, Xingxin Deng, Wei-Ping Tang, Wenjun
- 机构：E China Inst Theoret Phys;Chinese Acad Sci;AstraZeneca Global R&D
- 来源：ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 2016
- 关键词：asymmetric catalysis enantioselectivity ligand design rhodium total synthesis
- 质疑
- The copper-catalyzed asymmetric construction of a dispiropyrrolidine skeleton via 1,3-dipolar cycloaddition of azomethine ylides to α-alkylidene succinimides被引量：70收藏
- 作者：Yang, Wu-Lin Liu, Yang-Zi Luo, Shuai Yu, Xingxin Fossey, John S. Deng, Wei-Ping
- 机构：E China Univ Sci & Technol;Univ Birmingham
- 来源：CHEMICAL COMMUNICATIONS 2015
- 质疑
- Cu(I)-Catalyzed Chemoselective and Stereoselective [3+3] Cycloaddition of Azomethine Ylides with 2-Indolylnitroethylenes: Facile Access to Highly Substituted Tetrahydro-γ-Carbolines被引量：66收藏
- 作者：Yang, Wu-Lin Li, Chun-Yan Qin, Wen-Jing Tang, Fei-Fei Yu, Xingxin Deng, Wei-Ping
- 机构：East China Univ Sci & Technol; East China Univ Sci & Technol
- 来源：ACS CATALYSIS 2016
- 关键词：asymmetric catalysis chemoselectivity cycloaddition azomethine ylide tetrahydro-gamma-carboline
- 质疑
- Asymmetric Construction of Spirocyclic Pyrrolidine-thia(oxa)zolidinediones via N,O-Ligand/Cu(I) Catalyzed 1,3-Dipolar Cycloaddition of Azomethine Ylides with 5-Alkylidene Thia(oxa)zolidine-2,4-diones被引量：56收藏
- 作者：Yang, Wu-Lin Tang, Fei-Fei He, Fu-Sheng Li, Chun-Yan Yu, Xingxin Deng, Wei-Ping
- 机构：E China Univ Sci & Technol; E China Univ Sci & Technol
- 来源：ORGANIC LETTERS 2015
- 质疑
- TBAI/TBHP catalyzed direct N-acylation of sulfoximines with aldehydes被引量：34收藏
- 作者：Qin, Wen-Jing Li, Yi Yu, Xingxin Deng, Wei-Ping
- 机构：E China Univ Sci & Technol; E China Univ Sci & Technol
- 来源：TETRAHEDRON 2015
- 关键词：N-Acylation C(sp(2))-H activation Metal-free catalyst TBAI/TBHP catalyzed
- 质疑
- Unexpected O-H Insertion of Rhodium-Azavinylcarbenes with N-Acylhydrazones: Divergent Synthesis of 3,6-Disubstituted- and 3,5 6-Trisubstituted-1,2,4-Triazines被引量：34收藏
- 作者：Meng, Jiang Wen, Min Zhang, Shiwei Pan, Peiwen Yu, Xingxin Deng, Wei-Ping
- 机构：East China Univ Sci & Technol; East China Univ Sci & Technol
- 来源：JOURNAL OF ORGANIC CHEMISTRY 2017
- 关键词：Cyclization - Ketones - Reaction intermediates
- 质疑
- Rhodium(II)-Catalyzed Reaction of 1-Tosyl-1,2,3-triazoles with Morita-Baylis-Hillman Adducts: Synthesis of 3,4-Fused Pyrroles被引量：30收藏
- 作者：Jia, Renmeng Meng, Jiang Leng, Jiaying Yu, Xingxin Deng, Wei-Ping
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：CHEMISTRY-AN ASIAN JOURNAL 2018
- 关键词：pyrroles rhodium catalyzed synthetic methods triazoles
- 质疑
- Chiral N,O-Ligand/[Cu(OAc)2]-Catalyzed Asymmetric Construction of 4-Aminopyrrolidine Derivatives by 1,3-Dipolar Cycloaddition of Azomethine Ylides with -Phthalimidoacrylates被引量：29收藏
- 作者：Wang, Zheng Yu, Xingxin Tian, Bo-Xue Payne, Daniel T. Yang, Wu-Lin Liu, Yang-Zi Fossey, John S. Deng, Wei-Ping
- 机构：East China Univ Sci & Technol;Univ Calif San Francisco;Univ Birmingham
- 来源：CHEMISTRY-A EUROPEAN JOURNAL 2015
- 关键词：asymmetric synthesis copper cycloaddition density functional calculations ligands
- 质疑
- Asymmetric Construction of 3,4-Diamino Pyrrolidines via Chiral N,O-Ligand/Cu(I) Catalyzed 1,3-Dipolar Cycloaddition of Azomethine Ylides with β-Phthalimidonitroethene被引量：29收藏
- 作者：He, Fu-Sheng Zhu, Han Wang, Zheng Gao, Ming Yu, Xingxin Deng, Wei-Ping
- 机构：E China Univ Sci & Technol; E China Univ Sci & Technol
- 来源：ORGANIC LETTERS 2015
- 质疑
- Highly Regio-, Diastereo-, and Enantioselective Assembly of Azepino[2,3-b]indoles via Palladium-Catalyzed [4+3] Cycloaddition被引量：28收藏
- 作者：Yang, Wu-Lin Huang, Zesheng Liu, Yang-Zi Yu, Xingxin Deng, Wei-Ping
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Zhejiang Normal Univ
- 来源：CHINESE JOURNAL OF CHEMISTRY 2020
- 关键词：Asymmetric catalysis Palladium [4+3] Cycloaddition Trimethylenemethane Azepino[2,3-b]indole Synthetic method
- 质疑
- Cu(OAc)2/FOXAP complex catalyzed construction of 2,5-dihydropyrrole derivatives via asymmetric 1,3-dipolar cycloaddition of azomethine ylides to ethynyl ketones被引量：28收藏
- 作者：Tang, Fei-Fei Yang, Wu-Lin Yu, Xingxin Deng, Wei-Ping
- 机构：E China Univ Sci & Technol
- 来源：CATALYSIS SCIENCE & TECHNOLOGY 2015
- 关键词：Catalysis - Ketones
- 质疑
- In silico prediction of hERG blockers using machine learning and deep learning approaches被引量：25收藏
- 作者：Chen, Yuanting Yu, Xinxin Li, Weihua Tang, Yun Liu, Guixia
- 机构：East China Univ Sci & Technol
- 来源：JOURNAL OF APPLIED TOXICOLOGY 2023
- 关键词：applicability domain GCN hERG blocker machine learning structural alerts
- 质疑
- Synthesis of 2,5-epoxy-1,4-benzoxazepines via rhodium(II)-catalyzed reaction of 1-tosyl-1,2,3-triazoles and salicylaldehydes被引量：24收藏
- 作者：Meng, Jiang Ding, Xiangfeng Yu, Xingxin Deng, Wei-Ping
- 机构：E China Univ Sci & Technol
- 来源：TETRAHEDRON 2016
- 关键词：1-Tosyl-1,2,3-triazoles alpha-Imino carbenes Zwitterionic intermediates Polycyclic ethers Azaheterocycles
- 质疑
- Ligand-controlled switch in diastereoselectivities: catalytic asymmetric construction of spirocyclic pyrrolidine-azetidine/oxe(thie)tane derivatives被引量：24收藏
- 作者：Deng, Hua Jia, Renmeng Yang, Wu-Lin Yu, Xingxin Deng, Wei-Ping
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：CHEMICAL COMMUNICATIONS 2019
- 质疑
- Carbon-Carbon Bond Formation by Reaction of Rhodium Azavinylcarbenes with Secondary Amides: Access to Indigo Analogues from Isatins被引量：16收藏
- 作者：Meng, Jiang Jia, Renmeng Leng, Jiaying Wen, Min Yu, Xingxin Deng, Wei-Ping
- 机构：East China Univ Sci & Technol; East China Univ Sci & Technol
- 来源：ORGANIC LETTERS 2017
- 质疑
- Unambiguous Identification of -Tubulin as the Direct Cellular Target Responsible for the Cytotoxicity of Chalcone by Photoaffinity Labeling被引量：15收藏
- 作者：Zhou, Bo Yu, Xingxin Zhuang, Chunlin Villalta, Peter Lin, Yong Lu, Junxuan Xing, Chengguo
- 机构：Univ Minnesota;East China Univ Sci & Technol;Second Mil Med Univ;Univ Minnesota;Lovelace Resp Res Inst
- 来源：CHEMMEDCHEM 2016
- 关键词：chalcones chemical probes cytotoxicity photoaffinity labeling tubulin
- 质疑
- XGraphCDS: An explainable deep learning model for predicting drug sensitivity from gene pathways and chemical structures被引量：15收藏
- 作者：Wang, Yimeng Yu, Xinxin Gu, Yaxin Li, Weihua Zhu, Keyun Chen, Long Tang, Yun Liu, Guixia
- 机构：East China Univ Sci & Technol
- 来源：COMPUTERS IN BIOLOGY AND MEDICINE 2024
- 关键词：Cancer drug sensitivity prediction Deep learning Gene pathways Chemical structures Interpretation
- 质疑
- Construction of 1H-pyrrol-2-ylphosphonates via [3+2] cycloaddition of phosphate azomethine ylides with ynones被引量：13收藏
- 作者：Meng, Jiang Wu, Di Shi, Ying Yu, Xingxin Deng, Wei-Ping
- 机构：E China Univ Sci & Technol
- 来源：TETRAHEDRON 2015
- 关键词：[3+2] Cycloaddition Pyrrole Phosphonate azomethine ylide Ynone 1H-Pyrrol-2-ylphosphonate
- 质疑
- Isolation, bioassay and 3D-QSAR analysis of 8-isopentenyl flavonoids from Epimedium sagittatum maxim. as PDE5A inhibitors被引量：13收藏
- 作者：Li, Juntao Wu, Yue Yu, Xinxin Zheng, Xinyu Xian, Jiechen Li, Senjie Shi, Wanyin Tang, Yun Chen, Zhe-Sheng Liu, Guixia Yao, Shen Xu, Jian Zheng, Xiangwei
- 机构：Shanghai Univ Tradit Chinese Med;Jing Brand Co Ltd;East China Univ Sci & Technol;Sanlin Community Hlth Serv Ctr Shanghai Pudong New;St Johns Univ
- 来源：CHINESE MEDICINE 2022
- 关键词：8-isopentenyl flavonoid The processed folium of Epimedium sagittatum Maxim Phosphodiesterase-5 inhibitor 3D-QSAR cGMP-PKG-Ca2+ signaling pathway
- 质疑
- Kinetic Resolution of α-Methylene-β-hydroxy Esters Catalyzed by Acyl Transfer Catalyst An-PIQ被引量：13收藏
- 作者：Jiang, Shan-Shan Xu, Qin-Chang Zhu, Ming-Yu Yu, Xingxin Deng, Wei-Ping
- 机构：E China Univ Sci & Technol
- 来源：JOURNAL OF ORGANIC CHEMISTRY 2015
- 关键词：Esters
- 质疑
- Fc-PIP Catalyzed Asymmetric Synthesis of cis-2,3-Dihydrobenzofurans被引量：12收藏
- 作者：Jiang, Shanshan Hu, Bin Yu, Xingxin Deng, Weiping
- 机构：E China Univ Sci & Technol
- 来源：CHINESE JOURNAL OF CHEMISTRY 2014
- 关键词：Michael addition-Lactonization dihydrobenzofuran Fc-PIP
- 质疑
- Enantioselective Rhodium-Catalyzed Addition of Arylboroxines to N-Unprotected Ketimines: Efficient Synthesis of Cipargamin被引量：12收藏
- 作者：Zhu, Jinbin Huang, Linwei Dong, Wei Li, Naikai Yu, Xingxin Deng, Wei-Ping Tang, Wenjun
- 机构：East China Univ Sci & Technol;Chinese Acad Sci
- 来源：ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 2019
- 关键词：asymmetric catalysis enantioselectivity ketimines Pligands rhodium
- 质疑
- Nonenzymatic kinetic resolution of α-aryl substituted allylic alcohols catalyzed by acyl transfer catalyst Np-PIQ被引量：11收藏
- 作者：Jiang, Shan-Shan Gu, Bo-Qi Zhu, Ming-Yu Yu, Xingxin Deng, Wei-Ping
- 机构：E China Univ Sci & Technol
- 来源：TETRAHEDRON 2015
- 关键词：Kinetic resolution Allylic alcohols Nucleophilic catalyst
- 质疑
- Silver(I) and Copper(I) Cocatalyzed Tandem Reaction of 2-Alkynylbenzaldoximes with Aldehydes or Alcohols: Approach to 4-Carboxylated Isoquinolines被引量：9收藏
- 作者：Wang, Xianbo Yu, Xingxin
- 机构：Nanchang Univ;E China Univ Sci & Technol
- 来源：JOURNAL OF ORGANIC CHEMISTRY 2014
- 关键词：Copper compounds - Silver compounds
- 质疑
- In silico prediction of ocular toxicity of compounds using explainable machine learning and deep learning approaches被引量：8收藏
- 作者：Zhou, Yiqing Wang, Ze Huang, Zejun Li, Weihua Chen, Yuanting Yu, Xinxin Tang, Yun Liu, Guixia
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：JOURNAL OF APPLIED TOXICOLOGY 2024
- 关键词：deep learning feature selection GCN machine learning model interpretability molecular descriptors ocular toxicity
- 质疑
- Promoting regular parental supervised toothbrushing: An additive intervention design adopting the Health Action Process Approach被引量：8收藏
- 作者：Chen, Yuanting Yu, Xinxin Li, Weihua Tang, Yun Liu, Guixia
- 机构：East China Univ Sci & Technol; Griffith Univ; Free Univ Berlin; SWPS Univ Social Psychol; Univ Calif
- 来源：APPLIED PSYCHOLOGY-HEALTH AND WELL BEING 2024
- 关键词：HAPA implementation intentions mental imagery parental supervised toothbrushing preschoolers
- 质疑
- ACtriplet: An improved deep learning model for activity cliffs prediction by in tegrating triplet loss and pre-training被引量：6收藏
- 作者：Yu, Xinxin Wang, Yimeng Chen, Long Li, Weihua Tang, Yun Liu, Guixia
- 机构：East China Univ Sci & Technol
- 来源：JOURNAL OF PHARMACEUTICAL ANALYSIS 2025
- 关键词：Activity cliff Triplet loss Deep learning Pre-training
- 质疑
- AptaDB: a comprehensive database integrating aptamer-target interactions被引量：6收藏
- 作者：Chen, Long Yu, Zhuohang Wu, Zengrui Zhou, Moran Wang, Yimeng Yu, Xinxin Li, Weihua Liu, Guixia Tang, Yun
- 机构：East China Univ Sci & Technol
- 来源：RNA 2024
- 关键词：aptamer-target interaction database annotation similar aptamers
- 质疑
