成果/Result
- Salt stress induced lipid accumulation in heterotrophic culture cells of Chlorella protothecoides: Mechanisms based on the multi-level analysis of oxidative response, key enzyme activity and biochemical alteration被引量：100收藏
- 作者：Wang, Tao Ge, Haiyan Liu, Tingting Tian, Xiwei Wang, Zejian Guo, Meijin Chu, Ju Zhuang, Yingping
- 机构：E China Univ Sci & Technol
- 来源：JOURNAL OF BIOTECHNOLOGY 2016
- 关键词：Chlorella protothecoides Heterotrophic culture Lipid Microalgae ROS Salt stress
- Antibiotic residue and toxicity assessment of wastewater during the pharmaceutical production processes被引量：79收藏
- 作者：Xue, JiaJia Lei, Dandan Zhao, Xiumei Hu, Yaru Yao, Shijie Lin, Kuangfei Wang, Zejian Cui, Changzheng
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Environm Protect Dept North China Pharmaceut Co L;East China Univ Sci & Technol
- 来源：CHEMOSPHERE 2022
- 关键词：Antibiotic production wastewater Antibiotic pollution Biological acute toxicity Vibrio fischeri Daphnia magna
- Multiple Propionyl Coenzyme A-Supplying Pathways for Production of the Bioplastic Poly(3-Hydroxybutyrate-co-3-Hydroxyvalerate) in Haloferax mediterranei被引量：76收藏
- 作者：Han, Jing Hou, Jing Zhang, Fan Ai, Guomin Li, Ming Cai, Shuangfeng Liu, Hailong Wang, Lei Wang, Zejian Zhang, Siliang Cai, Lei Zhao, Dahe Zhou, Jian Xiang, Hua
- 机构：Chinese Acad Sci;Univ Chinese Acad Sci;Chinese Acad Sci;E China Univ Sci & Technol
- 来源：APPLIED AND ENVIRONMENTAL MICROBIOLOGY 2013
- Improved vitamin B12 production by step-wise reduction of oxygen uptake rate under dissolved oxygen limiting level during fermentation process被引量：74收藏
- 作者：Wang, Ze-Jian Wang, Hui-Yuan Li, Yong-Liang Chu, Ju Huang, Ming-Zhi Zhuang, Ying-Ping Zhang, Si-Liang
- 机构：E China Univ Sci & Technol;Grp Hua Rong Pharmaceut Co Ltd
- 来源：BIORESOURCE TECHNOLOGY 2010
- 关键词：Vitamin B-12 Oxygen uptake rate Pseudomonas denitrificans Scale-up Oxygen supply strategy
- Characterization of the aroma-active compounds in black soybean sauce, a distinctive soy sauce被引量：66收藏
- 作者：Gao, Xianli Feng, Tuo Sheng, Mingjian Wang, Bo Wang, Zejian Shan, Pei Zhang, Yaqiong Ma, Haile
- 机构：Jiangsu Univ;Honworld Grp Ltd;East China Univ Sci & Technol
- 来源：FOOD CHEMISTRY 2021
- 关键词：Black soybean Black soybean sauce Soy sauce Aroma compound Aroma recombination
- Enhanced Biosynthesis of Chlorogenic Acid and Its Derivatives in Methyl-Jasmonate-Treated Gardenia jasminoides Cells: A Study on Metabolic and Transcriptional Responses of Cells被引量：63收藏
- 作者：Liu, Zebo Mohsin, Ali Wang, Zejian Zhu, Xiaofeng Zhuang, Yingping Cao, Liming Guo, Meijin Yin, Zhongping
- 机构： State Key Laboratory of Bioreactor Engineering; Jiangxi Key Laboratory of Natural Products and Functional Foods; Crop Breeding and Cultivation Research Institute
- 来源：Frontiers in Bioengineering and Biotechnology 2020
- 关键词：Biosynthesis - Plants (botany) - Signal transduction - Bacteriophages - Transcription
- Application of Euler-Lagrange CFD for quantitative evaluating the effect of shear force on Carthamus tinctorius L. cell in a stirred tank bioreactor被引量：49收藏
- 作者：Liu, Yu Wang, Ze-Jian Xia, Jian-Ye Haringa, Cees Liu, Ya-Ping Chu, Ju Zhuang, Ying-Ping Zhang, Si-Liang
- 机构：East China Univ Sci & Technol;Dalian Pract Biotechnol Co Ltd;Delft Univ Technol
- 来源：BIOCHEMICAL ENGINEERING JOURNAL 2016
- 关键词：Plant cell culture Fluid mechanics Agitation Power consumption C tinctorius L. cell Stress thresholds
- Multiple propionyl coenzyme a-supplying pathways for production of the bioplastic poly(3-Hydroxybutyrate-co-3-Hydroxyvalerate) in Haloferax mediterranei被引量：49收藏
- 作者：Han, Jing Hou, Jing Zhang, Fan Ai, Guomin Li, Ming Cai, Shuangfeng Liu, Hailong Wang, Lei Wang, Zejian Zhang, Siliang Cai, Lei Zhao, Dahe Zhou, Jian Xiang, Hua
- 机构： State Key Laboratory of Microbial Resources; University of Chinese Academy of Sciences; Beijing Institute of Genomics; State Key Laboratory of Bioreactor Engineering; University of Massachusetts
- 来源：Applied and Environmental Microbiology 2013
- 关键词：Biochemistry - Reinforced plastics - Coenzymes - Genes - Monomers
- Enhancing gluconic acid production by controlling the morphology of Aspergillus niger in submerged fermentation被引量：46收藏
- 作者：Lu, Fei Ping, Kangkang Wen, Ling Zhao, Wei Wang, Zejian Chu, Ju Zhuang, Yingping
- 机构：E China Univ Sci & Technol;Shan Dong Fuyang Biol Technol Co Ltd
- 来源：PROCESS BIOCHEMISTRY 2015
- 关键词：Gluconic acid Aspergillus niger Morphology Oxygen transfer rate Diffusion limitation
- A two-stage fed-batch heterotrophic culture of Chlorella protothecoides that combined nitrogen depletion with hyperosmotic stress strategy enhanced lipid yield and productivity被引量：45收藏
- 作者：Wang, Tao Tian, Xiwei Liu, Tingting Wang, Zejian Guan, Wenyan Guo, Meijin Chu, Ju Zhuang, Yingping
- 机构：East China Univ Sci & Technol
- 来源：PROCESS BIOCHEMISTRY 2017
- 关键词：Microalgae Lipid Glucose inhibition Hyperosmotic stress Two-stage fed-batch culture
- Degradation mechanism of PGNa by the immobilized degrading enzymes from magnetic fermentation residue biochar被引量：44收藏
- 作者：Zhang, Sinan Wang, Zejian Huang, Sheng Zhang, Jianmin Wu, Jiequn Wu, Shiyong
- 机构： Engineering Research Center of Resource Utilization of Carbon-containing Waste with Carbon Neutrality; State Key Laboratory of Coal Liquification; Department of Biotechnology; Hebei North China Pharmaceutical Huaheng Pharmaceutical Co.; Zhejiang University of Technology
- 来源：Science of the Total Environment 2025
- 关键词：Computer software reusability - Remediation - Reusability - Thermogravimetric analysis
- Kinetic analysis of curdlan production by Alcaligenes faecalis with maltose, sucrose, glucose and fructose as carbon sources被引量：42收藏
- 作者：Zhang, Qin Sun, Jingyun Wang, Zejian Hang, Haifeng Zhao, Wei Zhuang, Yingping Chu, Ju
- 机构： State Key Laboratory of Bioreactor Engineering; Shan Dong Fu Yang Biological Technology Co.
- 来源：Bioresource Technology 2018
- 关键词：Carbon - Rate constants - Fructose - Sugar (sucrose) - Biochemistry - Glucose - Growth kinetics - Fermentation - Maltose - Cell growth
- Improved vitamin B12 production by step-wise reduction of oxygen uptake rate under dissolved oxygen limiting level during fermentation process被引量：38收藏
- 作者：Wang, Ze-Jian Wang, Hui-Yuan Li, Yong-Liang Chu, Ju Huang, Ming-Zhi Zhuang, Ying-Ping Zhang, Si-Liang
- 机构： State Key Laboratory of Bioreactor Engineering; Shijiazhuang Pharma
- 来源：Bioresource Technology 2010
- 关键词：Fermentation - Bacteria - Biosynthesis - Cell growth - Process control - Oxygen supply - Biochemistry - Growth kinetics
- Dynamic Metabolism Mechanism of Halomonas Elongata Dsm 2581t Response to Nacl Shock Stress: An Effective Technology for Enhancing Ectoine Biosynthesis被引量：36收藏
- 作者：Yu, Junxiong Zhang, Yue Wang, Jing Liu, Yuxuan Mohisn, Ali Liu, Hao Zheng, Yanning Xing, Jianmin Zhuang, Yingping Guo, Meijin Wang, Zejian
- 机构： State Key Laboratory of Bioreactor Engineering; Department of Chemical Engineering for Energy Resources; State Key Laboratory of Microbial Resources; College of Chemical Engineering
- 来源：SSRN 2023
- 关键词：Biochemistry - Biosynthesis - Industrial research - Industrial water treatment - Metabolism - Metabolites - Wastewater treatment
- Kinetic analysis of curdlan production by Alcaligenes faecalis with maltose, sucrose, glucose and fructose as carbon sources被引量：33收藏
- 作者：Zhang, Qin Sun, Jingyun Wang, Zejian Hang, Haifeng Zhao, Wei Zhuang, Yingping Chu, Ju
- 机构：East China Univ Sci & Technol;Shan Dong Fu Yang Biol Technol Co Ltd
- 来源：BIORESOURCE TECHNOLOGY 2018
- 关键词：Alcaligenes faecalis Carbon sources Curdlan Kinetics
- Rationally optimized generation of integrated Escherichia coli with stable and high yield lycopene biosynthesis from heterologous mevalonate (MVA) and lycopene expression pathways被引量：32收藏
- 作者：Hussain, Muhammad Hammad Hong, Qi Zaman, Waqas Qamar Mohsin, Ali Wei, Yanlong Zhang, Ning Fang, Hongqing Wang, Zejian Hang, Haifeng Zhuang, Yingping Guo, Meijin
- 机构：East China Univ Sci & Technol;Natl Univ Sci & Technol NUST;Beijing Inst Biotechnol
- 来源：SYNTHETIC AND SYSTEMS BIOTECHNOLOGY 2021
- 关键词：Escherichia coli Lycopene biosynthesis Rational model of expression pathways Integrated MVA pathway Fermentation
- Efficient degradation of soybean protein B3 subunit in soy sauce by ultrasound-assisted prolyl endopeptidase and its primary mechanism被引量：30收藏
- 作者：Zhang, Zhankai Shan, Pei Zhang, Zhi-Hong He, Ronghai Xing, Limin Liu, Jianbin He, Degui Ma, Haile Wang, Zejian Gao, Xianli
- 机构：Jiangsu Univ;Honworld Grp Ltd;East China Univ Sci & Technol
- 来源：FOOD CHEMISTRY 2023
- 关键词：Soy sauce Ultrasound Prolyl endopeptidase Soybean protein Aspergillus oryzae Aspergillus niger
- Bioactive Indole Diketopiperazine Alkaloids from the Marine Endophytic Fungus Aspergillus sp. YJ191021被引量：29收藏
- 作者：Yang, Jin Gong, Lizhi Guo, Miaomiao Jiang, Yu Ding, Yi Wang, Zhijie Xin, Xiujuan An, Faliang
- 机构：East China Univ Sci & Technol;Beijing Technol & Business Univ
- 来源：MARINE DRUGS 2021
- 关键词：indole diketopiperazine alkaloids endophytic fungus Aspergillus sp antimicrobial
- Quantitative evaluation of the shear threshold on Carthamus tinctorius L. cell growth with computational fluid dynamics in shaken flask bioreactors被引量：26收藏
- 作者：Liu, Yu Wang, Ze-Jian Zhang, JianWen Xia, Jian-ye Chu, Ju Zhang, Si-Liang Zhuang, Ying-Ping
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Delft Univ Technol
- 来源：BIOCHEMICAL ENGINEERING JOURNAL 2016
- 关键词：Fluid mechanics Power consumption Aggregation Plant cell bioreactors C. tinctorius L. cell Stress thresholds
- Biodegradation of penicillin G sodium by Sphingobacterium sp. SQW1: Performance, degradation mechanism, and key enzymes被引量：26收藏
- 作者：Zhang, Sinan Liu, YuXuan Mohisn, Ali Zhang, Guohui Wang, Zejian Wu, Shiyong
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：JOURNAL OF HAZARDOUS MATERIALS 2024
- 关键词：Penicillin G sodium Biodegradation Degradation products Genomics
- Metabolic Dynamic Regulation Analysis of Ammonium Induced Efficient Nemadectin Biosynthesis of Streptomyces Cyaneogriseus被引量：25收藏
- 作者：Zhang, Zishu Song, Xiaoqing Zhang, Yun Xue, Jiayun Yu, Junxiong Wang, Zejian Moshin, Ali
- 机构： State Key Laboratory of Bioreactor Engineering
- 来源：SSRN 2025
- 关键词：Biosynthesis - Gene expression - Gene expression regulation - Metabolism - Metabolites
- Enhanced Biosynthesis of Chlorogenic Acid and Its Derivatives in Methyl-Jasmonate-Treated Gardenia jasminoides Cells: A Study on Metabolic and Transcriptional Responses of Cells被引量：23收藏
- 作者：Liu, Zebo Mohsin, Ali Wang, Zejian Zhu, Xiaofeng Zhuang, Yingping Cao, Liming Guo, Meijin Yin, Zhongping
- 机构：East China Univ Sci & Technol;Jiangxi Agr Univ;Shanghai Acad Agr Sci
- 来源：FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY 2021
- 关键词：Gardenia jasminoides Ellis cultured cells chlorogenic acids methyl jasmonate elicitation transcriptome transcription factors
- Controlling the feed rate of glucose and propanol for the enhancement of erythromycin production and exploration of propanol metabolism fate by quantitative metabolic flux analysis被引量：22收藏
- 作者：Chen, Yong Huang, Mingzhi Wang, Zejian Chu, Ju Zhuang, Yingping Zhang, Siliang
- 机构：E China Univ Sci & Technol;Qingdao Agr Univ
- 来源：BIOPROCESS AND BIOSYSTEMS ENGINEERING 2013
- 关键词：Erythromycin Propanol Metabolic flux analysis Feeding strategy
- Optimization of polyhydroxyalkanoates fermentations with on-line capacitance measurement被引量：22收藏
- 作者：Li, Lan Wang, Ze-Jian Chen, Xue-Jun Chu, Ju Zhuang, Ying-Ping Zhang, Si-Liang
- 机构：E China Univ Sci & Technol;Grp Tian An Pharmaceut Co Ltd
- 来源：BIORESOURCE TECHNOLOGY 2014
- 关键词：On-line capacitance measurement Viable biomass PHAs Optimization
- A rapid and accurate quantification method for real-time dynamic analysis of cellular lipids during microalgal fermentation processes in Chlorella protothecoides with low field nuclear magnetic resonance被引量：22收藏
- 作者：Wang, Tao Liu, Tingting Wang, Zejian Tian, Xiwei Yang, Yi Guo, Meijin Chu, Ju Zhuang, Yingping
- 机构：E China Univ Sci & Technol;Niumag Corp Ltd
- 来源：JOURNAL OF MICROBIOLOGICAL METHODS 2016
- 关键词：Chlorella protothecoides LF-NMR Lipid Microalgae cells On-line determination
- A simple novel approach for real-time monitoring of sodium gluconate production by on-line physiological parameters in batch fermentation by Aspergillus niger被引量：21收藏
- 作者：Lu, Fei Wang, Zejian Zhao, Wei Chu, Ju Zhuang, Yingping
- 机构：E China Univ Sci & Technol;Shan Dong Fuyang Biol Technol Co Ltd
- 来源：BIORESOURCE TECHNOLOGY 2016
- 关键词：Sodium gluconate Aspergillus niger On-line parameters Real-time monitoring Oxygen limited
- Metabolic flux analysis of the central carbon metabolism of the industrial vitamin B12 producing strain Pseudomonas denitrificans using 13C-labeled glucose被引量：20收藏
- 作者：Wang, Ze-Jian Wang, Ping Liu, Yu-Wei Zhang, Yi-Ming Chu, Ju Huang, Ming-zhi Zhuang, Ying-Ping Zhang, Si-Liang
- 机构： State Key Laboratory of Bioreactor Engineering; Microbiology Laboratory of Hebei Medical University; Department of Chemical and Biological Engineering
- 来源：Journal of the Taiwan Institute of Chemical Engineers 2012
- 关键词：Bacteria - Cultivation - Physiology - Carbon - Oxygen supply - Amino acids - Metabolism
- Effect of pH, glucoamylase, pullulanase and invertase addition on the degradation of residual sugar in L-lactic acid fermentation by Bacillus coagulans HL-5 with corn flour hydrolysate被引量：20收藏
- 作者：Lv, Xiangyun Yu, Bo Tian, Xiwei Chen, Yu Wang, Zejian Zhuang, Yingping Wang, Yonghong
- 机构：E China Univ Sci & Technol;Shanghai Inst Biomfg Technol & Collaborat Innovat
- 来源：JOURNAL OF THE TAIWAN INSTITUTE OF CHEMICAL ENGINEERS 2016
- 关键词：pH Hydrolases addition Residual sugar L-Lactic acid Bacillus coagulans Corn flour hydrolysate
- Temporal dynamics of stress response in Halomonas elongata to NaCl shock: physiological, metabolomic, and transcriptomic insights被引量：19收藏
- 作者：Yu, Junxiong Zhang, Yue Liu, Hao Liu, Yuxuan Mohsin, Ali Liu, Zebo Zheng, Yanning Xing, Jianmin Han, Jing Zhuang, Yingping Guo, Meijin Wang, Zejian
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Chinese Acad Sci;Chinese Acad Sci
- 来源：MICROBIAL CELL FACTORIES 2024
- 关键词：Halomonas elongata Ectoine NaCl shock Stress response Osmotic stress Oxidative stress
- Enhancing nemadectin production by Streptomyces cyaneogriseus ssp noncyanogenus through quantitative evaluation and optimization of dissolved oxygen and shear force被引量：18收藏
- 作者：Song, Xiaoqing Zhang, Yun Xue, Jiayun Li, Chao Wang, Zejian Wang, Yonghong
- 机构：East China Univ Sci & Technol
- 来源：BIORESOURCE TECHNOLOGY 2018
- 关键词：Nemadectin Oxygen supply Shear stress Impeller configuration Computational fluid dynamics
