成果/Result
- The transcription factor ACE3 controls cellulase activities and lactose metabolism via two additional regulators in the fungus Trichoderma reesei被引量：71收藏
- 作者：Zhang, Jiajia Chen, Yumeng Wu, Chuan Liu, Pei Wang, Wei Wei, Dongzhi
- 机构：East China Univ Sci & Technol
- 来源：JOURNAL OF BIOLOGICAL CHEMISTRY 2019
- 关键词：Trichoderma reesei transcription factor protein-protein interaction cellulase DNA binding protein protein-DNA interaction gene expression fungi Hypocrea jecorina gene knockout ace3 protein-protein interaction transcription factor Trichoderma reesei (Hypocrea jecorina) Zn(II)2Cys6 protein renewables gene regulation hydrolase transcriptomics
- Enhanced cellulase production by decreasing intercellular pH through H+-ATPase gene deletion in Trichoderma reesei RUT-C30被引量：58收藏
- 作者：Liu, Pei Zhang, Guoxiu Chen, Yumeng Zhao, Jian Wang, Wei Wei, Dongzhi
- 机构： State Key Lab of Bioreactor Engineering
- 来源：Biotechnology for Biofuels 2019
- 关键词：Ammonia - Lignocellulose - Calcium - Carbon - Genes - Industrial chemicals
- Engineering of Trichoderma reesei for enhanced degradation of lignocellulosic biomass by truncation of the cellulase activator ACE3被引量：50收藏
- 作者：Chen, Yumeng Wu, Chuan Fan, Xingjia Zhao, Xinqing Zhao, Xihua Shen, Tao Wei, Dongzhi Wang, Wei
- 机构：East China Univ Sci & Technol;Shanghai Jiao Tong Univ;Jiangxi Normal Univ;Sunson Ind Grp Co Ltd
- 来源：BIOTECHNOLOGY FOR BIOFUELS 2020
- 关键词：Trichoderma reesei Genetic engineering Truncated ACE3 Cellulase production Lignocellulosic biomass
- Mn2+ modulates the expression of cellulase genes in Trichoderma reesei Rut-C30 via calcium signaling被引量：39收藏
- 作者：Chen, Yumeng Shen, Yaling Wang, Wei Wei, Dongzhi
- 机构：East China Univ Sci & Technol
- 来源：BIOTECHNOLOGY FOR BIOFUELS 2018
- 关键词：Trichoderma reesei Mn2+ stimulation Cellulase Mn2+ transport Calcium signaling TPMR1
- Enhancement of cellulase production in Trichoderma reesei RUT-C30 by comparative genomic screening被引量：31收藏
- 作者：Liu, Pei Lin, Aibo Zhang, Guoxiu Zhang, Jiajia Chen, Yumeng Shen, Tao Zhao, Jian Wei, Dongzhi Wang, Wei
- 机构：East China Univ Sci & Technol;Sunson Ind Grp Co Ltd
- 来源：MICROBIAL CELL FACTORIES 2019
- 关键词：Trichoderma reesei RUT-C30 Genome sequencing Cellulase production tre108642 tre56839 Alcohol dehydrogenase CRE1
- N,N-dimethylformamide induces cellulase production in the filamentous fungus Trichoderma reesei被引量：25收藏
- 作者：Chen, Yumeng Wu, Chuan Shen, Yaling Ma, Yushu Wei, Dongzhi Wang, Wei
- 机构：East China Univ Sci & Technol
- 来源：BIOTECHNOLOGY FOR BIOFUELS 2019
- 关键词：Trichoderma reesei DMF induced Cellulase Calcium signaling Permeability Phospholipase C plc-e
- Trichoderma reesei ACE4, a Novel Transcriptional Activator Involved in the Regulation of Cellulase Genes during Growth on Cellulose被引量：24收藏
- 作者：Chen, Yumeng Lin, Aibo Liu, Pei Fan, Xingjia Wu, Chuan Li, Ni Wei, Liujing Wang, Wei Wei, Dongzhi
- 机构：East China Univ Sci & Technol
- 来源：APPLIED AND ENVIRONMENTAL MICROBIOLOGY 2021
- 关键词：Trichoderma reesei cellulase gene transcription factor Zn(II)(2)Cys(6) protein ACE4
- Metabolic Engineering of Trichoderma reesei for L-Malic Acid Production被引量：23收藏
- 作者：Chen, Yumeng Han, Ao Wang, Meng Wei, Dongzhi Wang, Wei
- 机构：East China Univ Sci & Technol
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2023
- 关键词：Trichoderma reesei cell factory L-malic acid C4-dicarboxylate transporter rTCA pathway
- cAMP activates calcium signalling via phospholipase C to regulate cellulase production in the filamentous fungus Trichoderma reesei被引量：20收藏
- 作者：Chen, Yumeng Fan, Xingjia Zhao, Xinqing Shen, Yaling Xu, Xiangyang Wei, Liujing Wang, Wei Wei, Dongzhi
- 机构：East China Univ Sci & Technol;Shanghai Jiao Tong Univ;Zaozhuang Jie Nuo Enzyme Co Ltd
- 来源：BIOTECHNOLOGY FOR BIOFUELS 2021
- 关键词：Trichoderma reesei Cellulase Adenylate cyclase Calcium signalling Cyclic AMP Mn2+ DMF stimulation Filamentous fungi
- A simple approach to mediate genome editing in the filamentous fungus Trichoderma reesei by CRISPR/Cas9-coupled in vivo gRNA transcription被引量：20收藏
- 作者：Wu, Chuan Chen, Yumeng Qiu, Yifei Niu, Xiao Zhu, Ningjian Chen, Jiehui Yao, Hong Wang, Wei Ma, Yushu
- 机构：East China Univ Sci & Technol;East China Normal Univ
- 来源：BIOTECHNOLOGY LETTERS 2020
- 关键词：Filamentous fungus Trichoderma reesei CRISPR Cas9 In vivo gRNA transcription Gene editing
- Simultaneous Production of Cellulase and ?-Carotene in the Filamentous Fungus Trichoderma reesei被引量：19收藏
- 作者：Li, Jing Chen, Yumeng Gao, Ao Wei, Liujing Wei, Dongzhi Wang, Wei
- 机构：East China Univ Sci & Technol
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2023
- 关键词：Trichoderma reesei carotenoid ig -carotene cellulase waste mycelium
- An efficient shortened genetic transformation strategy for filamentous fungus Trichoderma reesei被引量：16收藏
- 作者：Wu, Chuan Chen, Yumeng Huang, Xiaoxue Sun, Shishuai Luo, Jinnan Lu, Zhiwen Wang, Wei Ma, Yushu
- 机构：East China Univ Sci & Technol
- 来源：JOURNAL OF GENERAL AND APPLIED MICROBIOLOGY 2019
- 关键词：G418 optimized codons Trichoderma reesei two-Agrobacterium-mediated transformation
- Induction of cellulase production by Sr2+ in Trichoderma reesei via calcium signaling transduction被引量：16收藏
- 作者：Li, Ni Zeng, Yi Chen, Yumeng Shen, Yaling Wang, Wei
- 机构：East China Univ Sci & Technol
- 来源：BIORESOURCES AND BIOPROCESSING 2022
- 关键词：Trichoderma reesei Sr2+ Cellulase ROS Calcium signaling Signal transduction
- Mechanism of Zn2+ regulation of cellulase production in Trichoderma reesei Rut-C30被引量：15收藏
- 作者：Li, Ni Li, Jing Chen, Yumeng Shen, Yaling Wei, Dongzhi Wang, Wei
- 机构：East China Univ Sci & Technol
- 来源：BIOTECHNOLOGY FOR BIOFUELS AND BIOPRODUCTS 2023
- 关键词：Trichoderma reesei Filamentous fungi Zn2+ stimulation Cellulase Plc-e zafA
- The novel repressor Rce2 competes with Ace3 to regulate cellulase gene expression in the filamentous fungus Trichoderma reesei被引量：15收藏
- 作者：Chen, Yumeng Wang, Wei Liu, Pei Lin, Aibo Fan, Xingjia Wu, Chuan Li, Ni Wei, Liujing Wei, Dongzhi
- 机构：East China Univ Sci & Technol
- 来源：MOLECULAR MICROBIOLOGY 2021
- 关键词：cellulase gene regulation repressor transcription factor Trichoderma reesei
- A three-gene cluster in Trichoderma reesei reveals a potential role of dmm2 in DNA repair and cellulase production被引量：14收藏
- 作者：Cai, Wanchuan Chen, Yumeng Zhang, Lei Fang, Xu Wang, Wei
- 机构：East China Univ Sci & Technol;Shandong Univ
- 来源：BIOTECHNOLOGY FOR BIOFUELS AND BIOPRODUCTS 2022
- 关键词：Trichoderma reesei DNA methylation modulator-2 tku70 Hem8 dmm2 Ferrochelatase Cellulase
- The Ras small GTPase RSR1 regulates cellulase production in Trichoderma reesei被引量：10收藏
- 作者：Li, Ni Qiu, Zhouyuan Cai, Wanchuan Shen, Yaling Wei, Dongzhi Chen, Yumeng Wang, Wei
- 机构：East China Univ Sci & Technol;Jiangsu Yiming Biol Technol Co Ltd
- 来源：BIOTECHNOLOGY FOR BIOFUELS AND BIOPRODUCTS 2023
- 关键词：Ras small GTPase RSR1 Cyclic AMP PKA Filamentous fungi Trichoderma reesei Cellulase Signaling
- Copper-mediated on-off control of gene expression in filamentous fungus Trichoderma reesei被引量：8收藏
- 作者：Wang, Wei Chen, Yumeng Wei, Dong-Zhi
- 机构：East China Univ Sci & Technol
- 来源：JOURNAL OF MICROBIOLOGICAL METHODS 2017
- 关键词：Trichoderma reesei Filamentous fungus Copper responsive promoter On-off control Unmarked genetic modification Marker rescue Gene expression Cre/loxP
- Enhanced cellulase production by decreasing intercellular pH through H+-ATPase gene deletion in Trichoderma reesei RUT-C30被引量：7收藏
- 作者：Liu, Pei Zhang, Guoxiu Chen, Yumeng Zhao, Jian Wang, Wei Wei, Dongzhi
- 机构：East China Univ Sci & Technol
- 来源：BIOTECHNOLOGY FOR BIOFUELS 2019
- 关键词：Trichoderma reesei Glucose H+-ATPase Intercellular pH Ca2+ channels Calcium signaling
- Roles of PKAc1 and CRE1 in cellulose degradation, conidiation, and yellow pigment synthesis in Trichoderma reesei QM6a被引量：5收藏
- 作者：Li, Ni Chen, Yumeng Shen, Yaling Wang, Wei
- 机构：East China Univ Sci & Technol
- 来源：BIOTECHNOLOGY LETTERS 2022
- 关键词：Carbon catabolite repressor Cellulase Protein kinase A Secondary metabolism Trichoderma reesei
- 分子生物学全英文课程建设的探索与实践被引量：4收藏
- 作者：陈雨蒙 蔡孟浩 吴海珍 范立强 赵健 张惠展 范建华
- 机构：华东理工大学生物工程学院应用生物学系
- 来源：《中国生物化学与分子生物学报》 2024
- 关键词：全英文授课 分子生物学 课程建设 专业英语
- 摘要：“分子生物学”是普通高等院校生物类相关专业的核心课。随着“双一流”建设、一流本科建设等政策的推进,全英文课程建设面对机遇与挑战。华东理工大学2019年首次开设《分子生物学全英文》课程,对课程建设进行了改革和实践,包括形象...
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- Metabolic Engineering of Filamentous Fungus Trichoderma reesei for Itaconic Acid Production被引量：3收藏
- 作者：Chen, Yumeng Wang, Ziwei Chen, Cangcang Xiao, Sheng Lv, Jia Lin, Ling Liu, Jiayu Li, Xinrui Wang, Wei Wei, Dongzhi
- 机构：East China Univ Sci & Technol
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2025
- 关键词：
Trichoderma reesei itaconic acid (IA) metabolic engineering cell factory
- Metformin regulates cellulase production in Trichoderma reesei via calcium signaling and mitochondrial function被引量：3收藏
- 作者：Wang, Jiajia Chen, Yumeng Cong, Jiawei Wang, Wei
- 机构：East China Univ Sci & Technol
- 来源：MICROBIAL CELL FACTORIES 2024
- 关键词：
Trichoderma reesei Metformin Cellulase Calcium signaling ROS Mitochondria
- Metabolic Engineering for the Comprehensive Utilization of N,N-Dimethylformamide-Containing Wastewater被引量：3收藏
- 作者：Chen, Yumeng Wang, Meng Wang, Wei Zeng, Yi Fan, Xingjia Tu, Maobing Ma, Yushu Wei, Dongzhi
- 机构：East China Univ Sci & Technol;Univ Cincinnati;Jiangsu YIMING Biol Technol CO LTD
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2022
- 关键词：cellulase N N-dimethylformamide separate enzymatic hydrolysis and fermentation succinate succinic acid cellulosic sugar
- Electrochemical Enzyme-Free Dopamine Sensor Based on Prussian Blue Analogues Oxides and MWCNTs被引量：2收藏
- 作者：Xu, Weixin Chen, Yumeng Liu, Yueling
- 机构：Affiliated Shanghai Univ Med & Hlth Sci;East China Univ Sci & Technol
- 来源：CHEMISTRYSELECT 2024
- 关键词：Enzyme-free Electrochemical sensors Prussian blue analogues oxides Multi-walled carbon nanotubes Dopamine
- Primers and copper responsive promoter design and data of real-time RT-PCR assay in filamentous fungus Trichoderma reesei被引量：0收藏
- 作者：Wang, Wei Chen, Yumeng Wei, Dong-Zhi
- 机构：East China Univ Sci & Technol
- 来源：DATA IN BRIEF 2018
- 关键词：Trichoderma reesei Filamentous fungus Copper responsive promoter Quantitative real-time PCR Plasmid construction Gene expression
- 基于丝状真菌里氏木霉构建L-苹果酸合成的细胞工厂被引量：0收藏
- 作者：陈雨蒙 王蒙 王玮 魏东芝
- 机构：生物反应器工程国家重点实验室华东理工大学
- 来源：《中国菌物学会2023年学术年会》 2023
- 关键词：丝状真菌 里氏木霉 四碳二元羧酸转运蛋白 L-苹果酸 过表达
- 摘要：L-苹果酸是一种重要的平台化学品,具有广泛的工业用途,市场需求巨大。丝状真菌里氏木霉(Trichoderma reesei)是美国食药监局定义的安全微生物,距今已有七十多年的研究历史。本研究以里氏木霉原始菌株QM6a作为...
- Computational-assisted protein engineering to develop thermostable and highly active catalase for industrial and biocatalytic applications被引量：0收藏
- 作者：Xu, Shuai Chen, Ya-min Meng, Xiang-yu Pan, Ru Yan, Ao-xuan Li, Zhi-min Li, Zong-lin
- 机构：East China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol
- 来源：BIORESOURCE TECHNOLOGY 2025
- 关键词：Deep learning Stability-activity tradeoff MD simulation Glycerol biotransformation
- Role of Trichoderma reesei Heterotrimeric G Protein Signaling in Growth and Cellulose Degradation被引量：0收藏
- 作者：Li, Ni Yang, Xinyu Cai, Wanchuan Chen, Yumeng Zhou, Zhihua Wang, Wei
- 机构：East China Univ Sci & Technol;Chinese Acad Sci;Nanjing Agr Univ;Chinese Acad Sci
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2026
- 关键词：G proteins Trichoderma reesei ACY1-cAMP-PKA pathway cellulase production
- Induction of cellulase production by Sr2? in Trichoderma reesei via calcium signaling transduction被引量：0收藏
- 作者：Ni Li Yi Zeng Yumeng Chen Yaling Shen Wei Wang
- 机构：The State Key Laboratory of Bioreactor Engineering
- 来源：生物资源与生物加工(英文) 2022
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