成果/Result
- Strategies to engineer various nanocarrier-based hybrid catalysts for enhanced chemodynamic cancer therapy被引量：117收藏
- 作者：Hao, Ji-Na Ge, Kaiming Chen, Guoli Dai, Bin Li, Yongsheng
- 机构：East China Univ Sci & Technol;Shihezi Univ
- 来源：CHEMICAL SOCIETY REVIEWS 2023
- 关键词：Cancer cells - Nanocatalysts - Nanosystems - Oxidation - Tumors
- A "Valve-Closing" Starvation Strategy for Amplification of Tumor-Specific Chemotherapy被引量：62收藏
- 作者：Li, Xianglong Jiang, Cong Wang, Qinghua Yang, Shaobo Cao, Yuanyuan Hao, Ji-Na Niu, Dechao Chen, Yan Han, Bo Jia, Xin Zhang, Peng Li, Yongsheng
- 机构：East China Univ Sci & Technol;Tongji Univ;Shihezi Univ;Shihezi Univ
- 来源：ADVANCED SCIENCE 2022
- 关键词：differential stress sensitization glucose metabolism GLUT1 inhibition stability-controllable nanomedicines starvation-sensitized chemotherapy
- Concurrent Modulation of Competitive Mechanisms to Design Stimuli-Responsive Ln-MOFs: A Light-Operated Dual-Mode Assay for Oxidative DNA Damage被引量：55收藏
- 作者：Hao, Ji-Na Li, Yongsheng
- 机构：East China Univ Sci & Technol
- 来源：ADVANCED FUNCTIONAL MATERIALS 2019
- 关键词：8-oxo-2'-deoxyguanosine competitive dual-mode assay luminescent metal-organic frameworks oxidative DNA damage
- Structure Engineering of a Lanthanide-Based Metal-Organic Framework for the Regulation of Dynamic Ranges and Sensitivities for Pheochromocytoma Diagnosis被引量：44收藏
- 作者：Hao, Ji-Na Niu, Dechao Gu, Jinlou Lin, Shaoliang Li, Yongsheng Shi, Jianlin
- 机构：East China Univ Sci & Technol;Chinese Acad Sci
- 来源：ADVANCED MATERIALS 2020
- 关键词：metal-organic frameworks pheochromocytoma diagnosis tailorable structures tunable biosensors vanillylmandelic acid
- GSH-Responsive Organosilica Hybrid Nanosystem as a Cascade Promoter for Enhanced Starvation and Chemodynamic Therapy被引量：42收藏
- 作者：Wu, Huan Li, Xianglong Liu, Shi Wang, Qinghua Cao, Yuanyuan Hao, Ji-Na Li, Yongsheng
- 机构：East China Univ Sci & Technol
- 来源：ADVANCED HEALTHCARE MATERIALS 2023
- 关键词：cascade reaction chemodynamic therapy GSH-responsive degradability hybrid nanoparticles starvation therapy
- Sensitive and Real-Time Assessment of DNA Methylation Degree by a Luminescent Lanthanide-Functionalized Mof Probe被引量：38收藏
- 作者：Chen, Guoli Hao, Ji-Na Li, Yongsheng
- 机构： Lab of Low-Dimensional Materials Chemistry; School of Chemistry and Chemical Engineering
- 来源：SSRN 2025
- 关键词：Alkylation - Body fluids - Europium alloys - Europium compounds - Metal-Organic Frameworks
- Synthesis of a Pillar[5]arene-Based Polyrotaxane for Enhancing the Drug Loading Capacity of PCL-Based Supramolecular Amphiphile as an Excellent Drug Delivery Platform被引量：37收藏
- 作者：He, Jianping Chen, Jianzhuang Lin, Shaoliang Niu, Dechao Hao, Jina Jia, Xiaobo Li, Nan Gu, Jinlou Li, Yongsheng Shi, Jianlin
- 机构：East China Univ Sci & Technol;Chinese Acad Sci
- 来源：BIOMACROMOLECULES 2018
- 关键词：Targeted drug delivery - Aromatic hydrocarbons - Crystallinity - Drug interactions - Controlled drug delivery
- Facile synthesis of organosilica-capped mesoporous silica nanocarriers with selective redox-triggered drug release properties for safe tumor chemotherapy被引量：35收藏
- 作者：Shen, Luying Pan, Shan Niu, Dechao He, Jianping Jia, Xiaobo Hao, Jina Gu, Jinlou Zhao, Wenru Li, Pei Li, Yongsheng
- 机构：East China Univ Sci & Technol;Hong Kong Polytech Univ
- 来源：BIOMATERIALS SCIENCE 2019
- 关键词：Mesoporous materials - Targeted drug delivery - Cytotoxicity - Silica nanoparticles - Sulfur compounds - Biocompatibility - Chemotherapy - Coupling agents - Biodegradation - Controlled drug delivery
- Biomimic Binding Affinity Gradients Triggered GSH-Response of Core-Shell Nanoparticles for Cascade Chemo/Chemodynamic Therapy被引量：34收藏
- 作者：Wang, Qinghua Li, Xianglong Mao, Jiayi Qin, Xing Yang, Shaobo Hao, Jina Guan, Mengjia Cao, Yuanyuan Li, Yongsheng
- 机构：East China Univ Sci & Technol;Shihezi Univ
- 来源：ADVANCED HEALTHCARE MATERIALS 2022
- 关键词：biomimic chemodynamic therapy glutathione response intracellular copper trafficking polydopamine
- Biodegradable organosilica magnetic micelles for magnetically targeted MRI and GSH-triggered tumor chemotherapy被引量：31收藏
- 作者：Yang, Tiangang Niu, Dechao Chen, Jianzhuang He, Jianping Yang, Shaobo Jia, Xiaobo Hao, Jina Zhao, Wenru Li, Yongsheng
- 机构：East China Univ Sci & Technol
- 来源：BIOMATERIALS SCIENCE 2019
- 关键词：Silica - Amino acids - Micelles - Medical applications - Tumors - Block copolymers - Targeted drug delivery - Biodegradability - Controlled drug delivery - Magnetite - Magnetic resonance imaging - Self assembly
- Tissue Engineering of JAK Inhibitor-Loaded Hierarchically Biomimetic Nanostructural Scaffold Targeting Cellular Senescence for Aged Bone Defect Repair and Bone Remolding被引量：26收藏
- 作者：Liu, Shi Jia, Xinlin Hao, Jina Zhang, Dapeng Yang, Shengchao Dai, Bin Mao, Yuanqing Li, Yongsheng
- 机构：East China Univ Sci & Technol;Shanghai Jiao Tong Univ;Shihezi Univ
- 来源：ADVANCED HEALTHCARE MATERIALS 2023
- 关键词：age-related bone repair JAK inhibitor osteoblast activity SASP senescence
- A smart luminescent metal-organic framework-based logic system for simultaneous analysis of copper ions and hydrogen sulfide被引量：25收藏
- 作者：Shu, Yufang Hao, Ji-Na Niu, Dechao Li, Yongsheng
- 机构：East China Univ Sci & Technol
- 来源：JOURNAL OF MATERIALS CHEMISTRY C 2020
- 关键词：Computer circuits - Hydrogen sulfide - Luminescence - Zirconium compounds - Copper compounds - Crystalline materials - Metal analysis - Metals - Organometallics - Metal ions
- Leap-Type Response of Redox/Photo-active Lanthanide-Based Metal-Organic Frameworks for Early and accurate Screening of Prostate Cancer被引量：19收藏
- 作者：Ge, Kaiming Chen, Guoli Zhang, Dapeng Hao, Ji-Na Li, Yongsheng
- 机构：East China Univ Sci & Technol;Shihezi Univ
- 来源：ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 2024
- 关键词：Luminescent Biosensors Lanthanide Metal-Organic Frameworks Defects Leap-Type Response Tumor Markers
- Multivalued Logic Assay of the Disease Marker of α-Ketoglutaric acid by a Luminescent MOF-Based Biosensor被引量：18收藏
- 作者：Dai, Xu Hao, Ji-Na Gu, Jinlou Li, Yongsheng
- 机构：East China Univ Sci & Technol
- 来源：ACS APPLIED BIO MATERIALS 2020
- 关键词：luminescent MOF biosensor multivalued logic assay disease marker alpha-ketoglutaric acid
- GSH/pH dual-responsive supramolecular hybrid vesicles for synergistic enzymatic/chemo-tumor therapy被引量：18收藏
- 作者：He, Jianping Chen, Jianzhuang Niu, Dechao Jia, Xiaobo Wang, Qinghua Hao, Jina Gu, Jinlou Li, Yongsheng Shi, Jianlin
- 机构：East China Univ Sci & Technol;Chinese Acad Sci
- 来源：APPLIED MATERIALS TODAY 2020
- 关键词：Dual-responsiveness Supramolecular hybrid vesicle Enzymatic/chemo-Synergistic therapy
- Dual "Unlocking" Strategy to Overcome Inefficient Nanomedicine Delivery and Tumor Hypoxia for Enhanced Photodynamic-Immunotherapy被引量：17收藏
- 作者：Li, Xianglong Jiang, Cong Jia, Xinlin Cao, Yuanyuan Mao, Yuanqing Hao, Ji-Na Yang, Yang Zhang, Peng Li, Yongsheng
- 机构：East China Univ Sci & Technol;Tongji Univ;Shanghai Jiao Tong Univ
- 来源：ADVANCED HEALTHCARE MATERIALS 2023
- 关键词：anti-programmed death-ligand 1 immunotherapy nanomedicine delivery photodynamic therapy tumor micro-vessel density modulation
- One-pot fabrication of a polydopamine-based nanoplatform for GSH triggered trimodal ROS-amplification for cancer therapy被引量：13收藏
- 作者：Wang, Qinghua Jia, Xinlin Li, Xianglong He, Miao Hao, Ji-Na Guan, Mengjia Mao, Yuanqing Cao, Yuanyuan Bin Dai Li, Yongsheng
- 机构：East China Univ Sci & Technol;Shanghai Jiao Tong Univ;Shihezi Univ
- 来源：BIOMATERIALS SCIENCE 2022
- 关键词：Antioxidants - Cell death - Controlled drug delivery - Copper - Diseases - Fabrication - Heavy ions - Medical nanotechnology - Metal ions - Oxidation - Targeted drug delivery
- Engineered Organosilica Hybrid Micelles for Photothermal-enhanced Starvation Cancer Therapy被引量：8收藏
- 作者：Li, Xianglong Wu, Huan Jiang, Cong Zou, Jinglin Wang, Qinghua Guan, Mengjia Hao, Ji-Na Cao, Yuanyuan Li, Yongsheng
- 机构：East China Univ Sci & Technol;Tongji Univ;Shihezi Univ
- 来源：CHEMISTRY-AN ASIAN JOURNAL 2022
- 关键词：organosilica hybrid micelles glucose oxidase starvation therapy photothermal effect
- Extraction-Induced Fabrication of Yolk-Shell-Structured Nanoparticles with Deformable Micellar Cores and Mesoporous Silica Shells for Multidrug Delivery被引量：7收藏
- 作者：Niu, Dechao Jiang, Yu He, Jianping Jia, Xiaobo Qin, Limei Hao, Jina Zhao, Wenru Dai, Bin Li, Yongsheng
- 机构：East China Univ Sci & Technol;Shihezi Univ
- 来源：ACS APPLIED BIO MATERIALS 2019
- 关键词：yolk-shell structure block copolymer mesoporous silica multidrug delivery tumor chemotherapy
- Luminescent metal-organic framework sensor for detection of biomarker 2-thiothiazolidine-4-carboxylic acid被引量：5收藏
- 作者：Ge, Kaiming Hao, Ji-Na Li, Yongsheng
- 机构：East China Univ Sci & Technol;Shihezi Univ
- 来源：CHINESE JOURNAL OF ANALYTICAL CHEMISTRY 2024
- 关键词：Optical biosensor Lanthanide metal-organic framework Biomarker 2-thiothiazolidine-4-carboxylic acid
- Quadruple functionalized copper-polydopamine nanoparticles for tumor-specific multimodal enhancing photodynamic therapy with low skin phototoxicity被引量：3收藏
- 作者：Zhong, Tianyu Wang, Qinghua Jiang, Cong Hao, Jina Guan, Mengjia Dai, Bin Jiang, Quan Zhang, Yong Cao, Yuanyuan Li, Yongsheng
- 机构：East China Univ Sci & Technol;Tongji Univ;Shihezi Univ;Fudan Univ
- 来源：APPLIED MATERIALS TODAY 2023
- 关键词：Stimulation-activated photodynamic therapy GSH response ROS amplification Polydopamine
- Sensitive and fast assessment of DNA methylation degree by a luminescent lanthanide-functionalized MOF probe被引量：3收藏
- 作者：Chen, Guoli Hao, Ji-Na Li, Yongsheng
- 机构：East China Univ Sci & Technol;Shihezi Univ
- 来源：MICROCHEMICAL JOURNAL 2025
- 关键词：Luminescent probes Lanthanides Metal-organic frameworks Biosensing DNA methylation
- Amplified and Inverted Circularly Polarized Luminescence with Color Evolution from Multiple-Constituent Coassemblies Directed by Diverse Noncovalent Forces被引量：2收藏
- 作者：Sang, Yunxiao Feng, Chen Liu, Min Hao, Ji-Na Zhou, Quan Lin, Shaoliang Zhang, Weihua Wang, Fang
- 机构：East China Univ Sci & Technol;Nanjing Agr Univ;East China Univ Sci & Technol
- 来源：ACS APPLIED MATERIALS & INTERFACES 2025
- 关键词：circularly polarized luminescence multiple-constituentcoassembly noncovalent forces chirality supramolecular chemistry
- Redox-responsive engineered hybrid nanomedicine for gallbladder cancer therapy via hyaluronic acid depletion被引量：2收藏
- 作者：Zou, Jinglin Jiang, Cong Li, Xianglong Zhong, Tianyu Wang, Shuqi Wang, Bo Zhang, Dapeng Hao, Ji-Na Cao, Yuanyuan Guan, Mengjia Zhang, Peng Dai, Bin Li, Yongsheng
- 机构：East China Univ Sci & Technol;Tongji Univ;Shihezi Univ;Shanghai Jiao Tong Univ
- 来源：APPLIED MATERIALS TODAY 2023
- 关键词：Gallbladder cancer Extracellular matrix Hyaluronidase Nanocarrier Redox-responsive
- Ordered-Pore-Structure Engineering of Dual-Emissive Lanthanide-Based Metal-Organic Frameworks for Boosting Sensing Performance of Tumor Marker被引量：2收藏
- 作者：Li, Wen Ge, Kaiming Hao, Ji-Na Li, Yongsheng
- 机构：East China Univ Sci & Technol
- 来源：ANALYTICAL CHEMISTRY 2025
- 关键词：Crystalline materials - Diagnosis - Diseases - Mesopores - Micropores - Microporosity - Organometallics - Pore structure - Probes - Reliability analysis - Screening
- A highly luminescent lanthanide-functionalized covalent organic framework for rapid and specific detection of 7-methylguanine for DNA methylation assessment被引量：1收藏
- 作者：Hu, Tao Hao, Ji-Na Li, Yongsheng
- 机构：East China Univ Sci & Technol;Shihezi Univ
- 来源：BIOMATERIALS SCIENCE 2024
- 关键词：Alkylation - Biomarkers - Body fluids - Methylation
- 双激发驱动的全组分响应镧系金属-有机骨架用于多 元疾病标志物的双模式检测被引量：1收藏
- 作者：Chen, Guoli Dai, Bin Hao, Ji-Na Li, Yongsheng
- 机构：East China Univ Sci & Technol;Shihezi Univ
- 来源：[1]East China Univ Sci & Technol, Minist Educ,Frontier Sci Ctr Mat Biol & Dynam Chem, Shanghai Engn Res Ctr Hierarch Nanomat, Sch Mat Sci & Engn,Lab Low Dimens Mat Chem,Key Lab, Shanghai 200237, Peoples R China;[2]Shihezi Univ, Sch Chem & Chem Engn, State Key Lab Incubat Base Green Proc Chem Engn, Shihezi 832003, Peoples R China 2025
- Controllable construction of imine-linked covalent organic frameworks with regular morphologies by a stepwise feeding-engineered uniform polymerization strategy被引量：0收藏
- 作者：Yao, Xing Li, Wen Hao, Ji-Na Li, Yongsheng
- 机构：East China Univ Sci & Technol;Shihezi Univ
- 来源：APPLIED MATERIALS TODAY 2025
- 关键词：Covalent organic framework Controllable synthesis Morphology modulation Stepwise feeding process Diverse structures
- Machine Learning-guided Prediction of Ionizable Amphiphilic Janus Dendrimers for mRNA Nanomedicine被引量：0收藏
- 作者：Cheng, Wan-Ting Zheng, Heng-Li Zhu, Peng-Yu Hao, Ji-Na Zhang, Da-Peng Li, Yong-Sheng
- 机构：East China Univ Sci & Technol
- 来源：CHINESE JOURNAL OF POLYMER SCIENCE 2026
- 关键词：Janus dendrimer Machine learning mRNA delivery Molecular modeling
