成果/Result
- Metabolic engineering of oleaginous yeast Yarrowia lipolytica for limonene overproduction被引量：134收藏
- 作者：Cao, Xuan Lv, Yu-Bei Chen, Jun Imanaka, Tadayuki Wei, Liu-Jing Hua, Qiang
- 机构：East China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol
- 来源：BIOTECHNOLOGY FOR BIOFUELS 2016
- 关键词：Limonene Yarrowia lipolytica Neryl diphosphate synthase 1 Limonene synthase
- Enhanced squalene biosynthesis in Yarrowia lipolytica based on metabolically engineered acetyl-CoA metabolism被引量：82收藏
- 作者：Huang, Yu-Ying Jian, Xing-Xing Lv, Yu-Bei Nian, Ke-Qing Gao, Qi Chen, Jun Wei, Liu-Jing Hua, Qiang
- 机构：East China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol
- 来源：JOURNAL OF BIOTECHNOLOGY 2018
- 关键词：Yarrowia lipolytica Acetyl-CoA Squalene Metabolic network model Terpenoid
- Metabolic engineering of β-carotene biosynthesis in Yarrowia lipolytica被引量：72收藏
- 作者：Zhang, Xin-Kai Wang, Dan-Ni Chen, Jun Liu, Zhi-Jie Wei, Liu-Jing Hua, Qiang
- 机构：East China Univ Sci & Technol;Hubei Univ Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol
- 来源：BIOTECHNOLOGY LETTERS 2020
- 关键词：Yarrowia lipolytica beta-carotene CRISPR Cas9 system Metabolic engineering Fermenter cultivation
- Elevating Limonene Production in Oleaginous Yeast Yarrowia lipolytica via Genetic Engineering of Limonene Biosynthesis Pathway and Optimization of Medium Composition被引量：59收藏
- 作者：Cheng, Bo-Qian Wei, Liu-Jing Lv, Yu-Bei Chen, Jun Hua, Qiang
- 机构：East China Univ Sci & Technol;SCICBT
- 来源：BIOTECHNOLOGY AND BIOPROCESS ENGINEERING 2019
- 关键词：limonene Yarrowia lipolytica carbon source fed-batch fermentation
- Multicopy integrants of crt genes and co-expression of AMP deaminase improve lycopene production in Yarrowia lipolytica被引量：58收藏
- 作者：Zhang, Xin-Kai Nie, Ming-Yue Chen, Jun Wei, Liu-Jing Hua, Qiang
- 机构：East China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol
- 来源：JOURNAL OF BIOTECHNOLOGY 2019
- 关键词：Lycopene Yarrowia lipolytica Multicopy integration AMP deaminase overexpression Fermenter cultivation
- Combining adaptive laboratory evolution and metabolic engineering for efficient erythritol production from crude glycerol by Yarrowia lipolytica被引量：55收藏
- 作者：Zhao, Ling-Xuan Li, Jiawei Wang, Ya-Ting Zhu, Qin-Yi Chen, Jun Liu, Zhi-Jie Liu, Feng Hua, Qiang
- 机构： State Key Laboratory of Bioreactor Engineering; State Key Laboratory of Microbial Metabolism; Key Laboratory of Fermentation Engineering
- 来源：Journal of Biotechnology 2026
- 关键词：Biochemistry - Fermentation - Food additives - Glycerol - Metabolic engineering
- Anaerobic Degradation of Paraffins by Thermophilic Actinobacteria under Methanogenic Conditions被引量：45收藏
- 作者：Liu, Yi-Fan Chen, Jing Liu, Zhong-Lin Shou, Li-Bin Lin, Dan-Dan Zhou, Lei Yang, Shi-Zhong Liu, Jin-Feng Li, Wei Gu, Ji-Dong Mu, Bo-Zhong
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;Shanghai Inst Pollut Control & Ecol Secur;East China Univ Sci & Technol
- 来源：ENVIRONMENTAL SCIENCE & TECHNOLOGY 2020
- 关键词：Petroleum reservoirs - Petroleum reservoir engineering - Addition reactions - Carbon dioxide - Methane
- Enhancement of VEGF-Mediated Angiogenesis by 2-N,6-O-Sulfated Chitosan-Coated Hierarchical PLGA Scaffolds被引量：41收藏
- 作者：Yu, Yuanman Chen, Jie Chen, Rui Cao, Lingyan Tang, Wei Lin, Dan Wang, Jing Liu, Changsheng
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol;E China Univ Sci & Technol
- 来源：ACS APPLIED MATERIALS & INTERFACES 2015
- 关键词：Scaffold poly(lactic-co-glycolic acid) sulfated chitosan vascular endothelial growth factor angiogenesis
- Metabolome analysis and pathway abundance profiling of Yarrowia lipolytica cultivated on different carbon sources被引量：40收藏
- 作者：Zhao, Chen Gu, Deqing Nambou, Komi Wei, Liujing Chen, Jun Imanaka, Tadayuki Hua, Qiang
- 机构：E China Univ Sci & Technol;SCICBT
- 来源：JOURNAL OF BIOTECHNOLOGY 2015
- 关键词：Yarrowia lipolytica Metabolomics Pathway abundance Carbon sources Lipid production
- Designing of a "cheap to run'' fermentation platform for an enhanced production of single cell oil from Yarrowia lipolytica DSM3286 as a potential feedstock for biodiesel被引量：39收藏
- 作者：Nambou, Komi Zhao, Chen Wei, Liujing Chen, Jun Imanaka, Tadayuki Hua, Qiang
- 机构：E China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol
- 来源：BIORESOURCE TECHNOLOGY 2014
- 关键词：Biodiesel Fermentation Lipids Phosphate limitation Yarrowia lipolytica
- Analysis of metabolic fluxes for better understanding of mechanisms related to lipid accumulation in oleaginous yeast Trichosporon cutaneum被引量：35收藏
- 作者：Liu, Zhijie Gao, Yang Chen, Jun Imanaka, Tadayuki Bao, Jie Hua, Qiang
- 机构： State Key Laboratory of Bioreactor Engineering; Department of Biotechnology
- 来源：Bioresource Technology 2013
- 关键词：Yeast - Biodiesel - Metabolism - Sulfur compounds - Nitrogen compounds - Enzymes
- Enhancement of BMP-2-mediated angiogenesis and osteogenesis by 2-N,6-O-sulfated chitosan in bone regeneration被引量：32收藏
- 作者：Pan, Yuanzhong Chen, Jie Yu, Yuanman Dai, Kai Wang, Jing Liu, Changsheng
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：BIOMATERIALS SCIENCE 2018
- 关键词：Biosynthesis - Bone - ProtEIns - Sulfur compounds
- Methanogenic Degradation of Long n-Alkanes Requires Fumarate-Dependent Activation被引量：28收藏
- 作者：Ji, Jia-Heng Liu, Yi-Fan Zhou, Lei Mbadinga, Serge Maurice Pan, Pan Chen, Jing Liu, Jin-Feng Yang, Shi-Zhong Sand, Wolfgang Gu, Ji-Dong Mu, Bo-Zhong
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Donghua Univ;Freiberg Univ Min & Technol;Univ Duisburg Essen
- 来源：APPLIED AND ENVIRONMENTAL MICROBIOLOGY 2019
- 关键词：(1-methylalkyl)succinate biodegradation fumarate addition hydrocarbon long n-alkanes methanogenesis
- Multiple gene integration to promote erythritol production on glycerol in Yarrowia lipolytica被引量：27收藏
- 作者：Zhang, Ling Nie, Ming-Yue Liu, Feng Chen, Jun Wei, Liu-Jing Hua, Qiang
- 机构：East China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol
- 来源：BIOTECHNOLOGY LETTERS 2021
- 关键词：Erythritol Glycerol utilization Multiple gene integration Ribose 5-phosphate isomerase Yarrowia lipolytica
- Enhancing Trans-Nerolidol Productivity in Yarrowia lipolytica by Improving Precursor Supply and Optimizing Nerolidol Synthase Activity被引量：23收藏
- 作者：Liu, Feng Liu, Shun-Cheng Qi, Yi-Ke Liu, Zhijie Chen, Jun Wei, Liu-Jing Hua, Qiang
- 机构：East China Univ Sci & Technol;North China Univ Sci & Technol;Hubei Univ Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2022
- 关键词：trans-nerolidol protEIn engineering peroxisomal acetyl-CoA pool pathway compartmentation Yarrowia lipolytica
- Process optimization with alternative carbon sources and modulation of secondary metabolism for enhanced ansamitocin P-3 production in Actinosynnema pretiosum被引量：22收藏
- 作者：Fan, Yuxiang Gao, Yang Zhou, Jie Wei, Liujing Chen, Jun Hua, Qiang
- 机构：E China Univ Sci & Technol;SCICBT
- 来源：JOURNAL OF BIOTECHNOLOGY 2014
- 关键词：Actinosynnema pretiosum Ansamitocin P-3 Fructose Medium optimization Transcription analysis
- Methanogenic degradation of branched alkanes in enrichment cultures of production water from a high-temperature petroleum reservoir被引量：21收藏
- 作者：Chen, Jing Liu, Yi-Fan Zhou, Lei Mbadinga, Serge Maurice Yang, Tao Zhou, Jing Liu, Jin-Feng Yang, Shi-Zhong Gu, Ji-Dong Mu, Bo-Zhong
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Univ Hong Kong;East China Univ Sci & Technol
- 来源：APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 2019
- 关键词：Alkylsuccinate iso-Alkanes or branched alkanes High-temperature petroleum reservoir Methanogenic degradation assA gene
- Metabolic profiling and flux distributions reveal a key role of acetyl-CoA in sophorolipid synthesis by Candida bombicola被引量：21收藏
- 作者：Yang, Linbing Li, Youyuan Zhang, Xinkai Liu, Ting Chen, Jun Wei, Liujing Hua, Qiang
- 机构：East China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol
- 来源：BIOCHEMICAL ENGINEERING JOURNAL 2019
- 关键词：Sophorolipid Metabolic flux Metabolic profile Acetyl-CoA Candida bombicola Biosurfactant
- Recovery of dilute aqueous butanol by membrane vapor extraction with dodecane or mesitylene被引量：21收藏
- 作者：Chen, J. Razdan, N. Field, T. Liu, D. E. Wolski, P. Cao, X. Prausnitz, J. M. Radke, C. J.
- 机构：Univ Calif Berkeley;East China Univ Sci & Technol
- 来源：JOURNAL OF MEMBRANE SCIENCE 2017
- 关键词：Membrane vapor extraction Mass-transfer resistance Butanol or furfural recovery Recirculation flow cell Dodecane Mesitylene
- Evaluation of metabolome sample preparation methods regarding leakage reduction for the oleaginous yeast Yarrowia lipolytica被引量：20收藏
- 作者：Zhao, Chen Nambou, Komi Wei, Liujing Chen, Jun Imanaka, Tadayuki Hua, Qiang
- 机构：E China Univ Sci & Technol
- 来源：BIOCHEMICAL ENGINEERING JOURNAL 2014
- 关键词：Yeast Metabolomics Separation Optimisation Amino acids DMSO quenching
- Reconstruction of genome-scale metabolic model of Yarrowia lipolytica and its application in overproduction of triacylglycerol被引量：19收藏
- 作者：Wei, Songsong Jian, Xingxing Chen, Jun Zhang, Cheng Hua, Qiang
- 机构：East China Univ Sci & Technol;KTH Royal Inst Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol
- 来源：BIORESOURCES AND BIOPROCESSING 2017
- 关键词：Yarrowia lipolytica Genome-scale metabolic model iYL_2.0 Triacylglycerol Gene-level prediction targets
- Development of an economical fermentation platform for enhanced ansamitocin P-3 production in Actinosynnema pretiosum被引量：18收藏
- 作者：Liu, Ting Bessembayeya, Lyailya Chen, Jun Wei, Liu-Jing Hua, Qiang
- 机构：East China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol
- 来源：BIORESOURCES AND BIOPROCESSING 2019
- 关键词：Ansamitocin P-3 Cane molasses Soybean powder Medium optimization
- Long-Term Cultivation and Meta-Omics Reveal Methylotrophic Methanogenesis in Hydrocarbon-Impacted Habitats被引量：17收藏
- 作者：Liu, Yi-Fan Chen, Jing Liu, Zhong-Lin Hou, Zhao-Wei Liang, Bo Wang, Li-Ying Zhou, Lei Shou, Li-Bin Lin, Dan-Dan Yang, Shi-Zhong Liu, Jin-Feng Wu, Xiao-Lin Gu, Ji-Dong Mu, Bo-Zhong
- 机构：East China Univ Sci & Technol;Daqing Oilfield Co Ltd;Guangdong Technion Israel Inst Technol;Shanghai Inst Pollut Control & Ecol Secur;East China Univ Sci & Technol
- 来源：ENGINEERING 2023
- 关键词：Methanogenic hydrocarbon degradation Oily sludge Bioremediation Alkanes
- Metabolomic changes and metabolic responses to expression of heterologous biosynthetic genes for lycopene production in Yarrowia lipolytica被引量：17收藏
- 作者：Zhao, Chen Gao, Qi Chen, Jun Wei, Liujing Imanaka, Tadayuki Hua, Qiang
- 机构：East China Univ Sci & Technol;Northwest A&F Univ;Shanghai Collaborat Innovat Ctr Biomfg Technol
- 来源：JOURNAL OF BIOTECHNOLOGY 2017
- 关键词：Yarrowia lipolytica Metabolomics Pathway abundance Lipid Lycopene
- Production optimization and expression of pectin releasing enzyme from Aspergillus oryzae PO被引量：14收藏
- 作者：Chen, Jia Yang, Rujian Chen, Min Wang, Shaohua Li, Peng Xia, Yuelan Zhou, Li Xie, Jingli Wei, Dongzhi
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol
- 来源：CARBOHYDRATE POLYMERS 2014
- 关键词：Aspergillus oryzae Protopectinase Response surface methodology Endo-polygalacturonase
- Methanogenic biodegradation of C13 and C14 n-alkanes activated by addition to fumarate被引量：12收藏
- 作者：Ji, Jia-Heng Liu, Yi-Fan Zhou, Lei Irfan, Muhammad Mbadinga, Serge Maurice Pan, Pan Chen, Jing Liu, Jin-Feng Yang, Shi-Zhong Sand, Wolfgang Gu, Ji-Dong Mu, Bo-Zhong
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Univ Engn & Technol;Donghua Univ;Freiberg Univ Min & Technol
- 来源：INTERNATIONAL BIODETERIORATION & BIODEGRADATION 2020
- 关键词：1-methylalkyl succinate Alkane Fumarate addition Methanogenesis Smithella
- Establishment of a Fingerprint of Raspberries by LC被引量：11收藏
- 作者：Chen, Juan Lu, Yan-Hua Wei, Dong-Zhi Zhou, Xiao-Li
- 机构：E China Univ Chem Technol;Shanghai Inst Technol
- 来源：CHROMATOGRAPHIA 2009
- 关键词：Column liquid chromatography Raspberries Hyperoside Tiliroside Fingerprint Quality control
- Iterative gene integration mediated by 26S rDNA and non-homologous end joining for the efficient production of lycopene in Yarrowia lipolytica被引量：10收藏
- 作者：Luo, Zhen Shi, Jiang-Ting Chen, Xin-Liang Chen, Jun Liu, Feng Wei, Liu-Jing Hua, Qiang
- 机构：East China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol
- 来源：BIORESOURCES AND BIOPROCESSING 2023
- 关键词：Yarrowia lipolytica Lycopene Iterative gene integration Lipid Fermentation
- Metabolomics analysis of Actinosynnema pretiosum with improved AP-3 production by enhancing UDP-glucose biosynthesis被引量：9收藏
- 作者：Liu, Ting Jin, Ziwen Wang, Ziwei Chen, Jun Wei, Liu-Jing Hua, Qiang
- 机构：East China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol
- 来源：JOURNAL OF BIOSCIENCE AND BIOENGINEERING 2020
- 关键词：Actinosynnema pretiosum Ansamitocin P-3 Metabolomics Gene transcription UDP-glucose supply
- Metabolic engineering of erythritol production from glycerol by Yarrowia lipolytica被引量：6收藏
- 作者：Wang, Ya-Ting Zhao, Ling-Xuan Wei, Liu-Jing Chen, Jun Liu, Zhijie Liu, Feng Hua, Qiang
- 机构：East China Univ Sci & Technol;Hubei Univ Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol
- 来源：BIOTECHNOLOGY AND BIOPROCESS ENGINEERING 2024
- 关键词：Erythritol By-products Yarrowia lipolytica Metabolic engineering
