成果/Result
- Novel 1,3,4-Oxadiazole-2-carbohydrazides as Prospective Agricultural Antifungal Agents Potentially Targeting Succinate Dehydrogenase被引量：105收藏
- 作者：Wu, Yuan-Yuan Shao, Wu-Bin Zhu, Jian-Jun Long, Zhou-Qing Liu, Li-Wei Wang, Pei-Yi Li, Zhong Yang, Song
- 机构：Guizhou Univ;East China Univ Sci & Technol
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2019
- 关键词：1,3,4-oxadiazole carbohydrazide bioactivity succinate dehydrogenase inhibitor
- Rational Optimization and Action Mechanism of Novel Imidazole (or Imidazolium)-Labeled 1,3,4-Oxadiazole Thioethers as Promising Antibacterial Agents against Plant Bacterial Diseases被引量：75收藏
- 作者：Wang, Pei-Yi Wang, Ming-Wei Zeng, Dan Xiang, Meng Rao, Jia-Rui Liu, Qing-Qing Liu, Li -Wei Wu, Zhi-Bing Li, Zhong Song, Bao-An Yang, Song
- 机构：Guizhou Univ;East China Univ Sci & Technol
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2019
- 关键词：1,3,4-oxadiazole imidazole or imidazolium antibacterial action mechanism
- Antibacterial Functions and Proposed Modes of Action of Novel 1,2,3,4-Tetrahydro-β-carboline Derivatives that Possess an Attractive 1,3-Diaminopropan-2-ol Pattern against Rice Bacterial Blight, Kiwifruit Bacterial Canker, and Citrus Bacterial Canker被引量：68收藏
- 作者：Liu, Hong-Wu Ji, Qing-Tian Ren, Gang-Gang Wang, Fang Su, Fen Wang, Pei-Yi Zhou, Xiang Wu, Zhi-Bing Li, Zhong Yang, Song
- 机构：Guizhou Univ;East China Univ Sci & Technol
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2020
- 关键词：tetrahydro-beta-carboline derivatives antiphytopathogen in vitro and in vivo bioassays ROS apoptosis hypersensitive response
- Pyrrole- and Dihydropyrrole-Fused Neonicotinoids: Design, Synthesis, and Insecticidal Evaluation被引量：64收藏
- 作者：Ye, Zhenjun Shi, Lina Shao, Xusheng Xu, Xiaoyong Xu, Zhiping Li, Zhong
- 机构：E China Univ Sci & Technol
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2013
- 关键词：Pyrrole dihydropyrrole neonicotinoid nAChR
- Synthesis and In Vitro and In Vivo Biological Activity Evaluation and Quantitative Proteome Profiling of Oxadiazoles Bearing Flexible Heterocyclic Patterns被引量：63收藏
- 作者：Tao, Qing-Qing Liu, Li-Wei Wang, Pei-Yi Long, Qing-Su Zhao, Yong-Liang Jin, Lin-Hong Xu, Wei-Ming Chen, Yang Li, Zhong Yang, Song
- 机构：Guizhou Univ;East China Univ Sci & Technol
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2019
- 关键词：oxadiazoles heterocyclic patterns biological activity quantitative proteomics
- Identification of Racemic and Chiral Carbazole Derivatives Containing an Isopropanolamine Linker as Prospective Surrogates against Plant Pathogenic Bacteria: In Vitro and In Vivo Assays and Quantitative Proteomics被引量：62收藏
- 作者：Zhao, Yong-Lian Huang, Xing Liu, Li-Wei Wang, Pei-Yi Long, Qing-Su Tao, Qing-Qing Li, Zhong Yang, Song
- 机构：Guizhou Univ;East China Univ Sci & Technol
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2019
- 关键词：carbazole isopropanolamine antibacterial proteomics action mechanism
- Characterization of hepatotoxic effects induced by pyraclostrobin in human HepG2 cells and zebrafish larvae被引量：60收藏
- 作者：Wu, Mengqi Bian, Jinhao Han, Shuang Zhang, Cheng Xu, Wenping Tao, Liming Li, Zhong Zhang, Yang
- 机构： Shanghai Key Laboratory of Chemical Biology; Department of Pathology; State Key Laboratory of Bioreactor Engineering
- 来源：Chemosphere 2023
- 关键词：Activation analysis - Disease control - Mitochondria
- Synthesis of Thiazolium-Labeled 1,3,4-Oxadiazole Thioethers as Prospective Antimicrobials: In Vitro and in Vivo Bioactivity and Mechanism of Action被引量：59收藏
- 作者：Wang, Ming-Wei Zhu, Huai-He Wang, Pei-Yi Zeng, Dan Wu, Yuan-Yuan Liu, Li-Wei Wu, Zhi-Bing Li, Zhong Yang, Song
- 机构：Guizhou Univ;East China Univ Sci & Technol
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2019
- 关键词：1,3,4-oxadiazole thiazolium antimicrobial 3D-QSAR proteomics action mechanism
- Developmental toxicity and estrogenicity of glyphosate in zebrafish in vivo and in silico studies被引量：58收藏
- 作者：Lu, Jian Zhang, Cheng Xu, Wenping Chen, Weidong Tao, Liming Li, Zhong Cheng, Jiagao Zhang, Yang
- 机构： Shanghai Key Laboratory of Chemical Biology; Department of Pathology
- 来源：Chemosphere 2023
- 关键词：Animals - Deep learning - Endocrine disrupters - Herbicides
- Surface Morphology and the Action Mechanism of Macrophage Immuno-Stimulating Activity of Rosa Setate X Rosa Rugosa Polysaccharide Wsrp-1b被引量：57收藏
- 作者：Wu, Mengqi Xu, Jingying Li, Wei Han, Qifeng Xia, Wei Li, Zhong Zhang, Yang Zhang, Wenqing
- 机构： Shanghai Key Laboratory of Chemical Biology; Shanghai Key Laboratory of Functional Materials Chemistry; State Key Laboratory of Dairy Biotechnology
- 来源：SSRN 2023
- 关键词：Antigen-antibody reactions - Azo dyes - Disease control - Electrophoresis - Morphology - Nitric oxide - Scanning electron microscopy - Surface morphology
- Synthesis and Nematicidal Activities of 1,2,3-Benzotriazin-4-one Derivatives against Meloidogyne incognita被引量：57收藏
- 作者：Wang, Gaolei Chen, Xiulei Deng, Yayun Li, Zhong Xu, Xiaoyong
- 机构：E China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2015
- 关键词：1,2,3-benzotriazin-4-one 2-cyanoiminothiazolidin-4-one nematicide Meloidogyne incognita in vivo
- Characterization of glyphosate-induced cardiovascular toxicity and apoptosis in zebrafish被引量：55收藏
- 作者：Lu, Jian Wang, Weiguo Zhang, Cheng Xu, Wenping Chen, Weidong Tao, Liming Li, Zhong Cheng, Jiagao Zhang, Yang
- 机构：East China Univ Sci & Technol;UT southwestern Med Ctr
- 来源：SCIENCE OF THE TOTAL ENVIRONMENT 2022
- 关键词：Glyphosate Developmental toxicity Heart Vascular Apoptosis Zebra fish
- Specific Synergist for Neonicotinoid Insecticides: IPPA08, a cis-Neonicotinoid Compound with a Unique Oxabridged Substructure被引量：53收藏
- 作者：Bao, Haibo Shao, Xusheng Zhang, Yixi Deng, Yayun Xu, Xiaoyong Liu, Zewen Li, Zhong
- 机构：Nanjing Agr Univ;E China Univ Sci & Technol
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2016
- 关键词：neonicotinoid insecticide synergist detoxification enzyme nicotinic acetylcholine receptors
- Cis-configuration: A new tactic/rationale for neonicotinoid molecular design被引量：52收藏
- 作者：Shao, Xusheng Lee, Philip W. Liu, Zewen Xu, Xiaoyong Li, Zhong Qian, Xuhong
- 机构： Shanghai Key Laboratory of Chemical Biology; Key Laboratory of Monitoring and Management of Plant Disease and Insect
- 来源：Journal of Agricultural and Food Chemistry 2011
- 关键词：Organic compounds
- Simultaneous Quantification of Hg2+ and MeHg+ in Aqueous Media with a Single Fluorescent Probe by Multiplexing in the Time Domain被引量：51收藏
- 作者：Zhang, Ziqian Zhang, Baoyan Qian, Xuhong Li, Zhong Xu, Zhiping Yang, Youjun
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol
- 来源：ANALYTICAL CHEMISTRY 2014
- 关键词：Cost effectiveness - Time domain analysis
- Synthesis and Docking Study of N-(Cinnamoyl)-N′-(substituted)acryloyl Hydrazide Derivatives Containing Pyridinium Moieties as a Novel Class of Filamentous Temperature-Sensitive ProtEIn Z Inhibitors against the Intractable Xanthomonas oryzae pv. oryzae Infections in Rice被引量：50收藏
- 作者：Zhou, Xiang Feng, Yu-Mei Qi, Pu-Ying Shao, Wu-Bin Wu, Zhi-Bing Liu, Li-Wei Wang, Yi Ma, Hao-Dong Wang, Pei-Yi Li, Zhong Yang, Song
- 机构：Guizhou Univ;East China Univ Sci & Technol
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2020
- 关键词：rice bacterial blight diacylhydrazine derivatives FtsZ inhibitor antibacterial assay
- Characterization of Glyphosate-Induced Cardiovascular Toxicity and Apoptosis in Zebrafish Embryos被引量：49收藏
- 作者：Lu, Jian Wang, Weiguo Zhang, Cheng Xu, Wenping Tao, Liming Li, Zhong Cheng, Jiagao Zhang, Yang
- 机构： Shanghai Key Laboratory of Chemical Biology; Department of Pathology
- 来源：SSRN 2022
- 关键词：Cell death - Health hazards - Herbicides
- Induction of developmental toxicity and cardiotoxicity in zebrafish embryos by Emamectin benzoate through oxidative stress被引量：46收藏
- 作者：Lu, Jian Wang, Weiguo Xu, Wenping Zhang, Chenggong Zhang, Cheng Tao, Liming Li, Zhong Zhang, Yang
- 机构：East China Univ Sci & Technol;Shanghai Municipal Bur Publ Secur;UT Southwestern Med Ctr
- 来源：SCIENCE OF THE TOTAL ENVIRONMENT 2022
- 关键词：Emamectin benzoate Developmental toxicity Oxidative stress Cardiotoxicity Zebrafish
- Cardiotoxicity risk induced by sanitary insecticide Dimefluthrin被引量：45收藏
- 作者：Li, Ruirui Zhou, Ning Zhang, Cheng Wu, Mengqi Xu, Wenping Cheng, Jiagao Tao, Liming Li, Zhong Zhang, Yang
- 机构： Shanghai Key Laboratory of Chemical Biology; Department of Pathology
- 来源：Chemosphere 2024
- 关键词：Cell death - Health risks - Heart - Insecticides - Polymerase chain reaction - Risk management
- Binding Difference of Fipronil with GABAARs in Fruitfly and Zebrafish: Insights from Homology Modeling, Docking, and Molecular Dynamics Simulation Studies被引量：44收藏
- 作者：Zheng, Nan Cheng, Jiagao Zhang, Wei Li, Weihua Shao, Xusheng Xu, Zhiping Xu, Xiaoyong Li, Zhong
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2014
- 关键词：fipronil GABA(A) receptors homology modeling docking molecular dynamics simulation
- Quantitative aggregation-activity relationship (QAAR): Supermolecular view, dimer as the simplest aggregation state and monomolecule被引量：44收藏
- 作者：Fan, Feng Li, Zhong Xu, Xiaoyong Qian, Xuhong
- 机构： Shanghai Key Laboratory of Chemical Biology; School of Pharmacy; State Key Laboratory of Elemento-Organic Chemistry
- 来源：QSAR and Combinatorial Science 2007
- 关键词：Bioactivity - Computational chemistry - Crystal structure
- Rational Exploration of Novel SDHI Fungicide through an Amide-?-ketonitrile Bioisosteric Replacement Strategy被引量：42收藏
- 作者：Zhou, Cong Sun, Xujuan Fu, Wen Li, Zhong Cheng, Jiagao Maienfisch, Peter
- 机构：East China Univ Sci & Technol
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2023
- 关键词：?-ketonitriles succinate dehydrogenase inhibitors fungicidal activity bioisosteric replacement molecular docking 3D-QSAR
- Difenoconazole induces oxidative DNA damage and mitochondria mediated apoptosis in SH-SY5Y cells被引量：42收藏
- 作者：Wang, Xin Ni, Hongfei Xu, Wenping Wu, Bing Xie, Te Zhang, Cheng Cheng, Jiagao Li, Zhong Tao, Liming Zhang, Yang
- 机构：East China Univ Sci & Technol;UT Southwestern Med Ctr
- 来源：CHEMOSPHERE 2021
- 关键词：Difenoconazole Cytotoxicity DNA damage Apoptosis Human neuroblastoma SH-SY5Y cells
- Cation sitting in aromatic cages: Ab initio computational studies on tetramethylammonium-(benzene)n (n=3-4) complexes被引量：41收藏
- 作者：Cheng, Jiagao Gong, Zhen Zhu, Weiliang Tang, Yun Li, Weihua Li, Zhong Jiang, Hualiang
- 机构： School of Science; Drug Discovery and Design Center; School of Pharmacy
- 来源：Journal of Physical Organic Chemistry 2007
- 关键词：Binding energy - Bond strength (chemical) - Positive ions - Quantum chemistry
- Degradation of chiral neonicotinoid insecticide cycloxaprid in flooded and anoxic soil被引量：40收藏
- 作者：Liu, Xuanqi Xu, Xiaoyong Li, Chao Zhang, Hanxue Fu, Qiuguo Shao, Xusheng Ye, Qingfu Li, Zhong
- 机构：E China Univ Sci & Technol;Zhejiang Univ
- 来源：CHEMOSPHERE 2015
- 关键词：Cycloxaprid Chiral Isotope labeling Soil degradation Dynamic Pathway
- Design, Synthesis, Crystal Structures, and Insecticidal Activities of EIght-Membered Azabridge Neonicotinoid Analogues被引量：39收藏
- 作者：Xu, Renbo Xia, Rui Luo, Ming Xu, Xiaoyong Cheng, Jiagao Shao, Xusheng Li, Zhong
- 机构：E China Univ Sci & Technol
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2014
- 关键词：oxabridge azabridge neonicotinoids insecticide
- Tetrahydroindeno[1′,2′:4,5]pyrrolo[1,2-a]imidazol-5(1H)-ones as Novel Neonicotinoid Insecticides: Reaction Selectivity and Substituent Effects on the Activity Level被引量：37收藏
- 作者：Chen, Nanyang Meng, Xiaoqing Zhu, Fengjuan Cheng, Jiagao Shao, Xusheng Li, Zhong
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2015
- 关键词：tetrahydroindeno[1 ',2 ':4,5]pyrrolo[1,2-a]imidazol-S(1H)-one insecticide activity synthesis
- Induction of Developmental Toxicity and Cardiotoxicity in Zebrafish Embryos by Emamectin Be Nzoatethrough Oxidative Stress被引量：37收藏
- 作者：Lu, Jian Xu, Wenping Wang, Weiguo Zhang, Chenggong Zhang, Cheng Tao, Liming Li, Zhong Zhang, Yang
- 机构： Shanghai Key Laboratory of Chemical Biology; Institute of forensic science shanghai municipal public security bureau; Department of Pathology
- 来源：SSRN 2021
- 关键词：Blood - Cell death - Toxicity - Transcription
- The effects of Spinosad on zebrafish larvae and THP-1 cells: Associated with immune cell damage and NF-kappa B signaling pathway activation被引量：37收藏
- 作者：Wang, Wei-Guo Xiong, Shou-Qian Lu, Jin Zhu, Lian-Hua Zhang, Cheng Cheng, Jia-Gao Li, Zhong Xu, Wen-Ping Tao, Li-Ming Zhang, Yang
- 机构： Shanghai Key Laboratory of Chemical Biology; Department of Pathology; Frog Prince Baby&Child Care Product Co.
- 来源：Chemosphere 2023
- 关键词：Antigen-antibody reactions - Cell signaling - Cytology - Macrophages - Signaling
- Stereoisomeric Isolation and Stereoselective Fate of Insecticide Paichongding in Flooded Paddy Soils被引量：36收藏
- 作者：Li, Juying Zhang, Jianbo Li, Chao Wang, Wei Yang, Zhen Wang, Haiyan Gan, Jay Ye, Qingfu Xu, Xiaoyong Li, Zhong
- 机构：Zhejiang Univ;E China Univ Sci & Technol;Univ Calif Riverside
- 来源：ENVIRONMENTAL SCIENCE & TECHNOLOGY 2013
- 关键词：Mineralogy - Insecticides - Floods - Stereoselectivity - Soils
