成果/Result
- Visualizing RNA dynamics in live cells with bright and stable fluorescent RNAs被引量：249收藏
- 作者：Chen, Xianjun Zhang, Dasheng Su, Ni Bao, Bingkun Xie, Xin Zuo, Fangting Yang, Lipeng Wang, Hui Jiang, Li Lin, Qiuning Fang, Mengyue Li, Ningfeng Hua, Xin Chen, Zhengda Bao, Chunyan Xu, Jinjin Du, Wenli Zhang, Lixin Zhao, Yuzheng Zhu, Linyong Loscalzo, Joseph Yang, Yi
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Chinese Acad Sci;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：NATURE BIOTECHNOLOGY 2019
- 关键词：Cells - Enzyme kinetics - Fluorescence - Mammals - Cytology
- An Artificial Molecular Shuttle Operates in Lipid Bilayers for Ion Transport被引量：182收藏
- 作者：Chen, Sujun Wang, Yichuan Nie, Ting Bao, Chunyan Wang, Chenxi Xu, Tianyi Lin, Qiuning Qu, Da-Hui Gong, Xueqing Yang, Yi Zhu, Linyong Tian, He
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 2018
- 关键词：Molecular electronics - Ion exchange - Ions - Stochastic systems
- Harnessing the intracellular triacylglycerols for titer improvement of polyketides in Streptomyces被引量：143收藏
- 作者：Wang, Weishan Li, Shanshan Li, Zilong Zhang, Jingyu Fan, Keqiang Tan, Gaoyi Ai, Guomin Lam, Sin Man Shui, Guanghou Yang, Zhiheng Lu, Hongzhong Jin, Pinjiao Li, Yihong Chen, Xiangyin Xia, Xuekui Liu, Xueting Dannelly, H. Kathleen Yang, Chen Yang, Yi Zhang, Siliang Alterovitz, Gil Xiang, Wensheng Zhang, Lixin
- 机构：Chinese Acad Sci;East China Univ Sci & Technol;Chinese Acad Agr Sci;Chinese Acad Sci;Qilu Univ Technol
- 来源：NATURE BIOTECHNOLOGY 2020
- 关键词：Ketones - Metabolism - Biochemistry - Bacteria - Metabolites - Glycerol
- Charge-Reversal APTES-Modified Mesoporous Silica Nanoparticles with High Drug Loading and Release Controllability被引量：121收藏
- 作者：Wang, Yifeng Sun, Yi Wang, Jine Yang, Yang Li, Yulin Yuan, Yuan Liu, Changsheng
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：ACS APPLIED MATERIALS & INTERFACES 2016
- 关键词：mesoporous silica nanocarriers charge reversal doxorubicin drug delivery pH responsive
- Selective and Ratiometric Fluorescent Trapping and Quantification of ProtEIn Vicinal Dithiols and in Situ Dynamic Tracing in Living Cells被引量：119收藏
- 作者：Huang, Chusen Jia, Ti Tang, Mengfang Yin, Qin Zhu, Weiping Zhang, Chao Yang, Yi Jia, Nengqin Xu, Yufang Qian, Xuhong
- 机构：E China Univ Sci & Technol;Shanghai Normal Univ;Shanghai Normal Univ
- 来源：JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 2014
- 关键词：Sulfur compounds - Cell membranes - Fluorescence imaging - Biosynthesis - Probes - Cytology
- Lighting Up Live-Cell and in Vivo Central Carbon Metabolism with Genetically Encoded Fluorescent Sensors被引量：98收藏
- 作者：Zhang, Zhuo Cheng, Xiawei Zhao, Yuzheng Yang, Yi
- 机构： Optogenetics and Synthetic Biology Interdisciplinary Research Center; Shanghai Key Laboratory of New Drug Design; CAS Center for Excellence in Brain Science
- 来源：Annual Review of Analytical Chemistry 2020
- 关键词：Metabolism - Cytology - Carbon - Fluorescence imaging - Biomolecules - Cells
- Highly Selective Fluorescent Probe for Vicinal-Dithiol-Containing ProtEIns and In Situ Imaging in Living Cells被引量：73收藏
- 作者：Huang, Chusen Yin, Qin Zhu, Weiping Yang, Yi Wang, Xin Qian, Xuhong Xu, Yufang
- 机构：E China Univ Sci & Technol
- 来源：ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 2011
- 关键词：fluorescent probes in situ imaging protEIn labeling redox proteomics vicinal dithiols
- A Light-Driven Molecular Machine Controls K+ Channel Transport and Induces Cancer Cell Apoptosis被引量：66收藏
- 作者：Yang, Huiting Yi, Jinhao Pang, Shihao Ye, Kai Ye, Zhicheng Duan, Qi Yan, Zexin Lian, Cheng Yang, Yi Zhu, Linyong Qu, Da-Hui Bao, Chunyan
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 2022
- 关键词：Apoptosis Ion Channels K+ Transport Light-Triggered Rotation Molecular Motor
- Optogenetic control of RNA function and metabolism using engineered light-switchable RNA-binding protEIns被引量：60收藏
- 作者：Liu, Renmei Yang, Jing Yao, Jing Zhao, Zhou He, Wei Su, Ni Zhang, Zeyi Zhang, Chenxia Zhang, Zhuo Cai, Haibo Zhu, Linyong Zhao, Yuzheng Quan, Shu Chen, Xianjun Yang, Yi
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;Chinese Acad Sci
- 来源：NATURE BIOTECHNOLOGY 2022
- 关键词：ProtEIns - Cell culture
- Construction and Characterization of a Novel Sustained-Release Delivery System for Hydrophobic Pesticides Using Biodegradable Polydopamine-Based Microcapsules被引量：50收藏
- 作者：Zou, Aihua Yang, Ying Cheng, Jiagao Garamus, Vasil M. Li, Na
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;Helmholtz Zentrum Geesthacht;Natl Ctr Prot Sci Shanghai
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2018
- 关键词：lambda-cyhalothrin pyrethroids microcapsule polydopamine self-polymerization sustained release
- Precise Construction of Cell-Instructive 3D Microenvironments by Photopatterning a Biodegradable Hydrogel被引量：50收藏
- 作者：Cai, Zhengwei Huang, Kaiping Bao, Chunyan Wang, Xuebin Sun, Xiangchao Xia, Hong Lin, Qiuning Yang, Yi Zhu, Linyong
- 机构：East China Univ Sci & Technol;Jilin Univ
- 来源：CHEMISTRY OF MATERIALS 2019
- 关键词：Biodegradation - Cells - Biomimetics - Cell culture
- Improving the thermostability of a GH11 xylanase by directed evolution and rational design guided by B-factor analysis被引量：47收藏
- 作者：Xing, Hongguan Zou, Gen Liu, Chunyan Chai, Shunxing Yan, Xing Li, Xinliang Liu, Rui Yang, Yi Zhou, Zhihua
- 机构：Chinese Acad Sci;East China Univ Sci & Technol;CJ Youtell Shanghai Biotech Co Ltd
- 来源：ENZYME AND MICROBIAL TECHNOLOGY 2021
- 关键词：Xylanase GH 11 Thermostability Directed evolution B-factors
- Oxidative phosphorylation enhances the leukemogenic capacity and resistance to chemotherapy of B cell acute lymphoblastic leukemia被引量：42收藏
- 作者：Chen, Chiqi Hao, Xiaoxin Lai, Xiaoyun Liu, Ligen Zhu, Jun Shao, Hongfang Huang, Dan Gu, Hao Zhang, Tinghua Yu, Zhuo Xie, Li Zhang, Xiaocui Yang, Yi Xu, Jun Zhao, Yuzheng Lu, Zhigang Zheng, Junke
- 机构：Shanghai Jiao Tong Univ;Shanghai Zhaxin Hosp;Shanghai Sixth Peoples Hosp;East China Univ Sci & Technol;Tongji Univ
- 来源：SCIENCE ADVANCES 2021
- 关键词：Diseases - Phosphorylation - Chemotherapy - Metabolism - Electric resistance - Cells - Cytology
- Micropatterned ProtEIn for Cell Adhesion through Phototriggered Charge Change in a Polyvinylpyrrolidone Hydrogel被引量：40收藏
- 作者：Ming, Zunzhen Ruan, Xing Bao, Chunyan Lin, Qiuning Yang, Yi Zhu, Linyong
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：ADVANCED FUNCTIONAL MATERIALS 2017
- 关键词：cell adhesion electrostatic interactions hydrogels photoregulation protEIn immobilization
- Moldable and Removable Wound Dressing Based on Dynamic Covalent Cross-Linking of Thiol-Aldehyde Addition被引量：39收藏
- 作者：Hua, Yujie Gan, Yibo Li, Pei Song, Lei Shi, Chunmeng Bao, Chunyan Yang, Yi Zhou, Qiang Lin, Qiuning Zhu, Linyong
- 机构：East China Univ Sci & Technol;Army Med Univ;Army Med Univ;Chongqing Med Univ
- 来源：ACS BIOMATERIALS SCIENCE & ENGINEERING 2019
- 关键词：dynamic covalent cross-linking thiol-aldehyde addition removable hydrogels wound dressing
- Adaptable to Mechanically Stable Hydrogels Based on the Dynamic Covalent Cross-Linking of Thiol-Aldehyde Addition被引量：38收藏
- 作者：Hua, Yujie Gan, Yibo Zhang, Yiqing Ouyang, Bin Tu, Bing Zhang, Chengmin Zhong, Xuepeng Bao, Chunyan Yang, Yi Lin, Qiuning Zhou, Qiang Zhu, Linyong
- 机构：East China Univ Sci & Technol;Army Med Univ;Army Med Univ
- 来源：ACS MACRO LETTERS 2019
- 关键词：Crosslinking - Addition reactions - pH - Aldehydes - Mechanical stability - Scaffolds
- Natural pyrethrins induce autophagy of HepG2 cells through the activation of AMPK/mTOR pathway被引量：38收藏
- 作者：Yang, Yun Gao, Jufang Zhang, Yang Xu, Wenping Hao, Youwu Xu, Zhiping Tao, Liming
- 机构：East China Univ Sci & Technol;Shanghai Normal Univ
- 来源：ENVIRONMENTAL POLLUTION 2018
- 关键词：Natural pyrethrins Autophagy HepG2 cells Oxidative stress AMPK/mTOR pathway
- Sequence analysis and heterologous expression of a new cytochrome P450 monooxygenase from Rhodococcus sp for asymmetric sulfoxidation被引量：38收藏
- 作者：Zhang, Jian-Dong Li, Ai-Tao Yang, Yi Xu, Jian-He
- 机构：E China Univ Sci & Technol
- 来源：APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 2010
- 关键词：Cytochrome P450 monooxygenase Rhodococcus sp Cloning Expression Asymmetric sulfoxidation
- Profiling metabolic states with genetically encoded fluorescent biosensors for NADH被引量：38收藏
- 作者：Zhao, Yuzheng Yang, Yi
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol
- 来源：CURRENT OPINION IN BIOTECHNOLOGY 2015
- 关键词：Metabolism
- Evaluation of the cytotoxic effects of glyphosate herbicides in human liver, lung, and nerve被引量：37收藏
- 作者：Hao, Youwu Zhang, Yang Ni, Hongfei Gao, Jufang Yang, Yun Xu, Wenping Tao, Liming
- 机构：East China Univ Sci & Technol;Shanghai Normal Univ
- 来源：JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART B-PESTICIDES FOOD CONTAMINANTS AND AGRICULTURAL WASTES 2019
- 关键词：Cytotoxicity ethoxylated formulant glyphosate herbicide human health pesticide
- Preparation of an Environmentally Friendly Formulation of the Insecticide Nicotine Hydrochloride through Encapsulation in Chitosan/Tripolyphosphate Nanoparticles被引量：37收藏
- 作者：Yang, Ying Cheng, Jiagao Garamus, Vasil M. Li, Na Zou, Aihua
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;Helmholtz Zentrum Geesthacht;Shanghai Inst Biochem & Cell Biol
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2018
- 关键词：nicotine chitosan tripolyphosphate ionic gelification monovalent salt effect environmentally safe formulations
- Glucose monitoring in living cells with single fluorescent protEIn-based sensors被引量：36收藏
- 作者：Hu, Hanyang Wei, Yufeng Wang, Daocheng Su, Ni Chen, Xianjun Zhao, Yuzheng Liu, Guixia Yang, Yi
- 机构：East China Univ Sci & Technol;Chinese Acad Sci;East China Univ Sci & Technol
- 来源：RSC ADVANCES 2018
- 关键词：ProtEIns - Escherichia coli - Cells - Cytology - Fluorescence - Metabolism - Glucose sensors
- Roundup? confers cytotoxicity through DNA damage and Mitochondria-Associated apoptosis induction被引量：32收藏
- 作者：Hao, Youwu Chen, Hui Xu, Wenping Gao, Jufang Yang, Yun Zhang, Yang Tao, Liming
- 机构：East China Univ Sci & Technol;Shanghai Normal Univ
- 来源：ENVIRONMENTAL POLLUTION 2019
- 关键词：Glyphosate-based herbicide Cytotoxicity DNA damage Mitochondria-associated apoptosis Human health risk
- Versatile Probes for the Selective Detection of Vicinal-Dithiol-Containing ProtEIns: Design, Synthesis, and Application in Living Cells被引量：31收藏
- 作者：Huang, Chusen Yin, Qin Meng, Jiangjiang Zhu, Weiping Yang, Yi Qian, Xuhong Xu, Yufang
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol
- 来源：CHEMISTRY-A EUROPEAN JOURNAL 2013
- 关键词：conjugation fluorescent probes imaging agents redox vicinal dithiols
- Advances in the role and mechanism of lactic acid bacteria in treating obesity被引量：30收藏
- 作者：Shen, Yi-Lin Zhang, Liu-Qing Yang, Ying Yin, Bin-Cheng Ye, Bang-Ce Zhou, Ying
- 机构：East China Univ Sci & Technol
- 来源：FOOD BIOENGINEERING 2022
- 关键词：antiobesity GABA lactic acid bacteria mechanism SCFAs
- Spatiotemporally controllable diphtheria toxin expression using a light-switchable transgene system combining multifunctional nanoparticle delivery system for targeted melanoma therapy被引量：28收藏
- 作者：He, Muye Wang, Yan Chen, Xianjun Zhao, Yuzheng Lou, Kaiyan Wang, Yujie Huang, Lei Hou, Xinyu Xu, Jiajun Cai, Xiaoran Cheng, Yi Lan, Minbo Yang, Yi Gao, Feng
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：JOURNAL OF CONTROLLED RELEASE 2020
- 关键词：Light-switchable gene expression Diphtheria toxin Melanoma Nanoparticle delivery system
- Exposure to environmental concentrations of natural pyrethrins induces hepatotoxicity: Assessment in HepG2 cell lines and zebrafish models被引量：25收藏
- 作者：Lu, Jian Yang, Yun Zhu, Lianhua Li, Meng Xu, Wenping Zhang, Cheng Cheng, Jiagao Tao, Liming Li, Zhong Zhang, Yang
- 机构：East China Univ Sci & Technol;UT Southwestern Med Ctr
- 来源：CHEMOSPHERE 2022
- 关键词：Natural pyrethrins Hepatotoxicity Oxidative stress DNA damage Repair HepG2 cells Zebrafish
- Unfolding and inactivation of abalone (Haliotis diversicolor) alkaline phosphatase during denaturation by guanidine hydrochloride被引量：25收藏
- 作者：Liao, Jin Hua Chen, Qing Xi Zhang, Qian Yang, Yi Shi, Yan
- 机构： Key Laboratory of Ministry of Education for Cell Biology and Tumor Cell Engineering; School of Pharmacy
- 来源：Applied Biochemistry and Biotechnology 2009
- 关键词：Conformations - Marine biology - Denaturation - Molecules - Alkalinity - Rate constants - Shellfish
- Ultrafast internal conversion dynamics of bilirubin bound to UnaG and its N57A mutant被引量：20收藏
- 作者：Cao, Xiaodan Zhang, Changcheng Gao, Ziheng Liu, Yangyi Zhao, Yuzheng Yang, Yi Chen, Jinquan Jimenez, Ralph Xu, Jianhua
- 机构：East China Normal Univ;NIST;Univ Colorado;Univ Colorado;East China Univ Sci & Technol
- 来源：PHYSICAL CHEMISTRY CHEMICAL PHYSICS 2019
- 关键词：Hydrogen bonds - Crystal structure - Chromophores - ProtEIns - Excited states
- Roundup-Induced AMPK/mTOR-Mediated Autophagy in Human A549 Cells被引量：18收藏
- 作者：Hao, Youwu Xu, Wenping Gao, Jufang Zhang, Yang Yang, Yun Tao, Liming
- 机构：East China Univ Sci & Technol;Shanghai Normal Univ
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2019
- 关键词：Roundup adjuvant POEA glyphosate isopropylamine salt A549 cells autophagy
