成果/Result
- Recent Advances and Future Developments in the Preparation of Polypeptides via N-Carboxyanhydride (NCA) Ring-Opening Polymerization被引量：68收藏
- 作者：Wu, Yueming Chen, Kang Wang, Jiangzhou Chen, Minzhang Dai, Wenhui Liu, Runhui
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 2024
- Heterochiral β-Peptide Polymers Combating Multidrug-Resistant Cancers Effectively without Inducing Drug Resistance被引量：67收藏
- 作者：Shao, Ning Yuan, Ling Ma, Pengcheng Zhou, Min Xiao, Ximian Cong, Zihao Wu, Yueming Xiao, Guohui Fei, Jian Liu, Runhui
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Shanghai Jiao Tong Univ
- 来源：JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 2022
- 关键词：Diseases - Biocompatibility - Cancer cells - Tumors
- Water-Insensitive Synthesis of Poly-β-Peptides with Defined Architecture被引量：66收藏
- 作者：Zhou, Min Xiao, Ximian Cong, Zihao Wu, Yueming Zhang, Wenjing Ma, Pengcheng Chen, Sheng Zhang, Haodong Zhang, Danfeng Zhang, Donghui Luan, Xiangfeng Mai, Yiyong Liu, Runhui
- 机构：East China Univ Sci & Technol;Shanghai Jiao Tong Univ
- 来源：ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 2020
- 关键词：polymerization poly-beta-peptides secondary structure water-insensitive polymerization beta-NTA
- Single-Center Trifunctional Organocatalyst Enables Fast and Controlled Polymerization on N-Carboxyanhydride被引量：53收藏
- 作者：Chen, Kang Wu, Yueming Chen, Minzhang Wang, Jiangzhou Zhou, Min Chen, Xin Liu, Runhui
- 机构： State Key Laboratory of Bioreactor Engineering; Shanghai Frontiers Science Center of Optogenetic Techniques for Cell Metabolism; Department of Biomaterials and Stem Cells; Key Laboratory for Ultrafine Materials
- 来源：ACS Central Science 2025
- 关键词：Carboxylation - Cationic polymerization - Organocatalyst - Reaction intermediates - Reaction rates - Ring opening polymerization
- Antimicrobial Properties and Application of Polysaccharides and ThEIr Derivatives被引量：51收藏
- 作者：Xia, Gui-Xue Wu, Yue-Ming Bi, Yu-Fang Chen, Kang Zhang, Wei-Wei Liu, Shi-Qi Zhang, Wen-Jing Liu, Run-Hui
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：CHINESE JOURNAL OF POLYMER SCIENCE 2021
- 关键词：Antimicrobial Drug resistance Polysaccharides Polysaccharide derivatives Chitosan
- Peptide-Mimicking Poly(2-oxazoline)s Possessing Potent Antifungal Activity and BBB Penetrating Property to Treat Invasive Infections and Meningitis被引量：47收藏
- 作者：Jiang, Weinan Zhou, Min Chen, Sheng Xie, Jiayang Chen, Minzhang Zhang, Haodong Wu, Yueming Chen, Xin Liu, Runhui
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 2023
- 关键词：Antifungal agents - Drug interactions - Mammals - Peptides
- Peptide polymer displaying potent activity against clinically isolated multidrug resistant Pseudomonas aeruginosa in vitro and in vivo被引量：41收藏
- 作者：Jiang, Weinan Xiao, Ximian Wu, Yueming Zhang, Weiwei Cong, Zihao Liu, Jingjing Chen, Sheng Zhang, Haodong Xie, Jiayang Deng, Shuai Chen, Minzhang Wang, Yun Shao, Xiaoyan Dai, Yidong Sun, Yun Fei, Jian Liu, Runhui
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;Shanghai Ruijin Rehabil Hosp;Shanghai Jiao Tong Univ
- 来源：BIOMATERIALS SCIENCE 2020
- 关键词：Antimicrobial agents - Bacteria - Antibiotics - Lithium compounds - Network security
- Reversing Anticancer Drug Resistance by Synergistic Combination of Chemotherapeutics and Membranolytic Antitumor β-Peptide Polymer被引量：27收藏
- 作者：Shao, Ning Yuan, Ling Liu, Longqiang Cong, Zihao Wang, Jiangzhou Wu, Yueming Liu, Runhui
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 2024
- 关键词：Cancer cells - Cells - Chemotherapy - Diseases
- A Polymeric Strategy Empowering Vascular Cell Selectivity and Potential Application Superior to Extracellular Matrix Peptides被引量：26收藏
- 作者：Zhou, Ruiyi Wu, Yueming Chen, Kang Zhang, Deteng Chen, Qi Zhang, Donghui She, Yunrui Zhang, Wenjing Liu, Longqiang Zhu, Yueqi Gao, Changyou Liu, Runhui
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Zhejiang Univ;Shanghai Jiao Tong Univ Affiliated Peoples Hosp 6;Soochow Univ
- 来源：ADVANCED MATERIALS 2022
- 关键词：EC-selective biomaterials endothelialization polymeric strategies vascular stents beta-peptide polymers
- Statistic Copolymers Working as Growth Factor-Binding Mimics of Fibronectin被引量：23收藏
- 作者：Zhang, Wenjing Wu, Yueming Chen, Qi Zhang, Haodong Zhou, Min Chen, Kang Cao, Chuntao Guo, Han Xu, Jianrong Liu, Honglai Lin, Haodong Liu, Changsheng Liu, Runhui
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Chinese Acad Sci;Shanghai Univ Tradit Chinese Med;East China Univ Sci & Technol
- 来源：ADVANCED SCIENCE 2022
- 关键词：fibronectin mimicking growth factor binding statistic copolymers
- Host defense peptide-mimicking peptide polymer-based antibacterial hydrogel enables efficient healing of MRSA-infected wounds被引量：19收藏
- 作者：Qiao, Zhongqian Zhang, Wenjing Wu, Yueming Jiang, Weinan Shao, Ning Xie, Jiayang Xia, Guixue Chen, Qimeng Liu, Zhefeng Zou, Jingcheng Gu, Jiawei Luan, Shifang Lin, Haodong Liu, Runhui
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Shanghai Jiao Tong Univ;Chinese Acad Sci
- 来源：SCIENCE CHINA-CHEMISTRY 2023
- 关键词：peptide polymer wound healing MRSA drug-resistance host defense peptide
- Biodegradable peptide polymers as alternatives to antibiotics used in aquaculture被引量：19收藏
- 作者：Ma, Pengcheng Wu, Yueming Jiang, Weinan Shao, Ning Zhou, Min Chen, Yuan Xie, Jiayang Qiao, Zhongqian Liu, Runhui
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：BIOMATERIALS SCIENCE 2022
- 关键词：Antibiotics - Aquaculture - Bacteria - Biodegradable polymers - Disease control
- Efficient synthesis of amino acid polymers for protEIn stabilization被引量：17收藏
- 作者：Li, Bing Wu, Yueming Zhang, Wenjing Zhang, Si Shao, Ning Zhang, Weiwei Zhang, Lixin Fei, Jian Dai, Yidong Liu, Runhui
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;Shanghai Jiao Tong Univ;Shanghai Ruijin Rehabil Hosp
- 来源：BIOMATERIALS SCIENCE 2019
- 关键词：Biosynthesis - High resolution transmission electron microscopy - Ring opening polymerization - Stabilization - Lithium compounds - ProtEIns - Dynamic light scattering - Phase locked loops
- Peptide-mimicking poly(2-oxazoline) displaying potent antibacterial and antibiofilm activities against multidrug-resistant Gram-positive pathogenic bacteria被引量：12收藏
- 作者：Cong, Zihao Yan, Zi Xiao, Ximian Liu, Longqiang Luo, Zhengjie Zou, Jingcheng Chen, Minzhang Wu, Yueming Zhou, Min Liu, Runhui
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Chinese Acad Sci
- 来源：JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY 2025
- 关键词：Poly(2-oxazoline)s Host defense peptide Antibiofilm MRSA Drug-resistance
- Advance and Designing Strategies in Polymeric Antifungal Agents Inspired by Membrane-Active Peptides被引量：10收藏
- 作者：Jiang, Weinan Wu, Yueming Zhou, Min Song, Gonghua Liu, Runhui
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：CHEMISTRY-A EUROPEAN JOURNAL 2022
- 关键词：antifungal polymer cell-penetrating peptides drug resistance host defense peptides peptidomimetics
- Self-Assembled Poly(sarcosine) Functionalized Host Defense Peptide-Mimicking Poly-β-Peptides for Combating Drug-Resistant Fungal Infection被引量：7收藏
- 作者：Xie, Jiayang Liu, Zhefeng Zhou, Min Luo, Zhengjie Liu, Longqiang Xiao, Ximian Jiang, Weinan Hu, Weilong Wu, Yueming Liu, Runhui
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Chinese Acad Sci
- 来源：ADVANCED FUNCTIONAL MATERIALS 2025
- 关键词：antifungal host defense peptide mimic poly(sarcosine) functionalized poly-beta-peptides self-assembly
- Controlled copolymerization of α-NCAs and α-NNTAs for preparing peptide/peptoid hybrid polymers with adjustable proteolysis被引量：7收藏
- 作者：Zou, Jingcheng Zhou, Min Ji, Zhemin Xiao, Ximian Wu, Yueming Cui, Ruxin Deng, Shuai Liu, Runhui
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：POLYMER CHEMISTRY 2022
- 关键词：Amino acids - Biocompatibility - Copolymerization - Proteolysis - Synthesis (chemical)
- 基于HDP模拟聚合物与利福平协同组合的口服脂质体治疗水产养殖细菌感染被引量：4收藏
- 作者：Yu, Haowen Chen, Luhang Wu, Yueming Dai, Wenhui Chen, Minzhang Chen, Yuan Liu, Longqiang Wang, Jiangzhou Huang, Xinqi Chen, Kang Liu, Runhui
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Chinese Acad Sci
- 来源：[1]East China Univ Sci & Technol, State Key Lab Bioreactor Engn, Shanghai 200237, Peoples R China;[2]East China Univ Sci & Technol, Shanghai Frontiers Sci Ctr Optogenet Tech Cell Met, Frontiers Sci Ctr Materiobiol & Dynam Chem, Engn Res Ctr Biomed Mat,Minist Educ,Key Lab Ultraf, Shanghai 200237, Peoples R China;[3]Chinese Acad Sci, Suzhou Inst Biomed Engn & Technol, Dept Biomat & Stem Cells, Suzhou 215163, Peoples R China 2025
- Cationic-Catalyst Strategy Enabling Ultrafast and Controlled Polymerization and Efficient Depolymerization Toward a Circular Polymer Economy被引量：1收藏
- 作者：Chen, Kang Wu, Yueming Chen, Minzhang Huang, Xinqi Zou, Jingcheng Chen, Xin Liu, Runhui
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Chinese Acad Sci;East China Univ Sci & Technol;Fudan Univ
- 来源：ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 2025
- 关键词：Amino acid polymer Cationic-catalyst strategy Circular polymer economy NCA polymerization Ultrafast and controlled polymerization
- An effective approach to obtain functional poly-β-peptides for combating drug-resistant bacterial infections被引量：1收藏
- 作者：Chen, Sheng Luo, Zhengjie Zhou, Min Xiao, Ximian Cong, Zihao Xie, Jiayang Wu, Yueming Zhang, Haodong Zhao, Xuebin Song, Gonghua Liu, Runhui
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Chinese Acad Sci;East China Univ Sci & Technol;Shanghai Shyndec Pharmaceut Co Ltd
- 来源：JOURNAL OF MATERIALS CHEMISTRY B 2025
- 关键词：Chain length
- Effective combinatorial antifungal therapy using a host defense peptide mimic that self-assembles into delivery micelles被引量：0收藏
- 作者：Liu, Longqiang Zhou, Min Xiao, Ximian Cong, Zihao Wu, Yueming Xie, Jiayang Zhang, Qiang Zhang, Junyu Jiang, Weinan Liu, Runhui
- 机构：East China Univ Sci & Technol;Chinese Acad Sci;East China Univ Sci & Technol;Shanghai Jiao Tong Univ
- 来源：NATURE BIOTECHNOLOGY 2026
- 关键词：Antifungal agents - Controlled drug delivery - Diseases - Fungi - Fungicides - Peptides - Targeted drug delivery
- 模拟宿主防御肽的聚(2-噁唑啉)作为佐剂增强多粘菌素B的抗菌活性并拓展抗菌谱被引量：0收藏
- 作者：罗政杰 赵学斌 周敏 邹景橙 肖希勉 刘龙强 谢佳洋 武月铭 张雯静 刘润辉
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Shanghai Jiao Tong Univ
- 来源：《Science China Materials》 2024
- 关键词：poly(2-oxazoline)s ESKAPE bacteria polymyxin B broad-spectrum activity
- 摘要：临床上常用的广谱抗生素无法有效解决抗生素高度耐药ESKAPE菌感染的难题,ESKAPE耐药菌已经成为人类生命健康的重大威胁.抗生素与佐剂的联合治疗是解决抗生素耐药菌感染的重要途径,但是探索对所有ESKAPE耐药菌都具有广...
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- Poly(bis(guanidinium)-oxazoline)-Insulin Complex Exerting Long-Acting Glucose-Responsive Insulin Release in Mice and Minipigs被引量：0收藏
- 作者：Zhang, Haodong Liang, Qian Jiang, Weinan Chen, Qi Chen, Kang Cong, Zihao Liu, Guojian Shi, Jia Ji, Yanxiu Li, Wenxin Dou, Mengyue Wang, Yuwen Liu, Longqiang Chen, Luhang Zhang, Donghui Wu, Yueming Liu, Runhui
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Chinese Acad Sci
- 来源：JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 2025
- 关键词：Electrostatics - Glucose - Insulin - Mammals
